Esketamine at a Clinical Dose Attenuates Cerebral Ischemia/Reperfusion Injury by Inhibiting AKT Signaling Pathway to Facilitate Microglia M2 Polarization and Autophagy by Gao Y, Li L, Zhao F, Cheng Y, Jin M, Xue FS

“…Furthermore, the effects of esketamine were enhanced by addition of autophagy inducer rapamycin.Conclusion: Esketamine at a clinical dose attenuates cerebral I/R injury by inhibiting AKT signaling pathway to facilitate microglial M2 polarization and autophagy. …”
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Diagnosis of Schizophrenia and Its Subtypes Using MRI and Machine Learning by Hosna Tavakoli, Reza Rostami, Reza Shalbaf, Mohammad‐Reza Nazem‐Zadeh

“…We extracted volumetrics of 66 subcortical and thickness of 72 cortical regions. Additionally, we obtained four graph‐based measures for 116 intracranial regions from rsfMRI data, including degree, betweenness centrality, participation coefficient, and local efficiency. …”
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Pharmacodynamic Profiling of Amoxicillin: Targeting Multidrug-Resistant Gram-Positive Pathogens <i>Staphylococcus aureus</i> and <i>Staphylococcus pseudintermedius</i> in Canine Cl... by Syed Al Jawad Sayem, Ga-Yeong Lee, Muhammad Aleem Abbas, Seung-Chun Park, Seung-Jin Lee

“…<b>Methods</b>: Minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), and mutation prevention concentration (MPC) were assessed. Additionally, time-kill assays and post-antibiotic effect (PAE) assessments were performed. …”
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E. W. Godwin’s Month in Normandy: Travel Writing as Intertext by Richard W. Hayes

“…Godwin (1833‒86) embarked on a month-long trip through France’s Normandy region, accompanied by his partner, the actress Ellen Terry (1847‒1928), and their daughter Edy. A year later, Godwin published a series of articles on this excursion in a Victorian architectural periodical, The Building News. …”
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Green analysis of illicit drugs on banknote dust by Teresa Cecchi, Arianna Giuliani, Carlo Catini

“…Avoiding the processing of a large number of banknotes is an additional aim of Green Analytical Chemistry, since it entails waste prevention and an efficient use of resources.…”
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How does the concentration of spatial allocation of urban construction land across cities affect carbon emission intensity in China? by Hui Yang, Cheng Chen, Jingye Li, Min Li, Stefan Sieber, Kaisheng Long

“…The heterogeneity analysis showed that the impact of CSA on CEI followed a U-shaped pattern in both the developed and developing regions, as well as in the eastern, central and western regions. Additionally, the analysis revealed a similar pattern in both the resource- and non-resource-based cities. …”
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HyQ2:&#x2009;A&#x2009;Hybrid&#x2009;Quantum&#x2009;Neural&#x2009;Network for&#x2009;NextG&#x2009;Vulnerability&#x2009;Detection by Yifeng Peng, Xinyi Li, Zhiding Liang, Ying Wang

“…The results show that the prediction accuracy and receiver operating characteristic AUC value fluctuate around 0.2&#x0025;, indicating HyQ2&#x2019;s robustness in noisy quantum environments. In addition, the noise resilience and robustness of the HyQ2 algorithm were substantiated through experiments on the IBM quantum machine with only a 0.2&#x0025; decrease compared to the simulation results.…”
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Designing the behavioral model of stakeholders in the corporate governance of iran's social security organization and its affiliated companies by Sepahdar Ansarinik, Seyed Jamaledin Tabibi

“…The Akaike Information Criterion (AIC) was 1812, closer to the saturated model index (1404) compared to the independent model (5660), indicating a good fit of the model.Originality/Value: Overall, six stakeholder groups were identified in the corporate governance of companies affiliated with the Social Security Organization: institutional stakeholders, government, political stakeholders, social networks, economic stakeholders, and shareholders. Additionally, six common behavioral indicators were identified among stakeholder groups: conflict resolution, building trust in the board of directors, political bargaining, power-politics relationships, goal setting, and decision-making processes. …”
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Use of virtual reality in port implantation to reduce perioperative anxiety and pain: protocol for a randomised controlled pilot trial at a single German university hospital (VIP-t... by Christoph W Michalski, Felix J Hüttner, Colette Dörr-Harim, Sandra Graf, Hannah Feldmann, Lisa S Hunold, Kira C Steinkraus, Nadir Nasir

“…Previous studies suggested that VR hypnosedation may reduce the use of sedatives or general anaesthesia, and may offer additional benefits such as reducing postoperative pain and nausea, and promoting faster patient discharge.Methods and analysis The VIP trial is a randomised controlled pilot trial comparing the usage of VR during port implantation with the current standard of care (local anaesthesia and analgosedation if needed). …”
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Impact of pulmonary yoga module on lung capacity of COVID-19 adult survivors by Adarsh Tomar, Sudhanshu Verma

“…BACKGROUND: Although every organ has its own importance in the human body, the significance of the lungs is vital. Numerous complications can occur if lungs are compressed; cardiovascular and respiratory diseases are most common in such circumstances. …”
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Item-level measurement properties of the pediatric awareness and sensory motor assessment in children with medical complexity by Brooke Mulrenin, Bryant A. Seamon, Carrie Cormack, Kimberly Lane Kascak, Cynthia Dodds

“…Adequate person reliability was observed (0.81), with 15% person misfit. Person misfit did not degrade item measures or model statistics. …”
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Soluble CD14 Enhances the Response of Periodontal Ligament Stem Cells to Toll-Like Receptor 2 Agonists by Christian Behm, Alice Blufstein, Johannes Gahn, Nazanin Noroozkhan, Andreas Moritz, Xiaohui Rausch-Fan, Oleh Andrukhov

“…Primary hPDLSCs were stimulated with synthetic lipopeptide Pam3CSK4 or lipoteichoic acid (LTA) in concentrations 1-1000 ng/ml in the presence/absence of sCD14 (250 ng/ml). Additionally, the effect of different sCD14 concentrations (2.5-250 ng/ml) on the TLR-2 response was determined in Pam3CSK4- or LTA-triggered hPDLSCs. …”
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Effects of Mycoplasma ovipneumoniae, abundance, and climate conditions on bighorn sheep lamb:ewe ratios in New Mexico by Colton J. Padilla, Caitlin Q. Ruhl, James W. Cain III, Matthew E. Gompper

“…Notably, population size was negatively related to Rocky Mountain juvenile:female ratios only after populations were exposed to M. ovipneumoniae. Additionally, climatic conditions in the previous lambing season and pre‐parturition time frame were associated with juvenile:female ratios for Rocky Mountain populations, while juvenile:female ratios of desert bighorn appeared to only be affected by pre‐parturition climatic conditions. …”
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Seleksi Fitur dengan Particle Swarm Optimization pada Klasifikasi Penyakit Parkinson Menggunakan XGBoost by Deni Kurnia, Muhammad Itqan Mazdadi, Dwi Kartini, Radityo Adi Nugroho, Friska Abadi

“…In this research, Particle Swarm Optimization is used as feature selection, while XGBoost will be used as a classification model. In addition, the model will also be applied SMOTE to overcome the problem of data class imbalance and hyperparameter tuning on XGBoost to get optimal hyperparameters. …”
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Synergistic fermentation of vitamin B2 (riboflavin) bio-enriched soy milk: optimization and techno-functional characterization of next generation functional vegan foods by Ananya Rana, Neetu Kumra Taneja, Anupama Singh, Tejpal Dhewa, Vikram Kumar, Ankur Kumar, Komal Chauhan, Vijay Juneja, Harinder Singh Oberoi

“…These conditions resulted in a threefold increase in B2 concentration (481 µg/L) while maintaining a probiotic count of 9 logs CFU/mL. Additionally, techno-functional characterization, including rheology and texture profile analysis, showed that enhanced protease activity of co-cultured LAB improved protein hydrolysis (6259 nm), positively impacting the water holding capacity (WHC) and overall acceptability of the fermented soymilk. …”
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Outdoor Massive MIMO Testbed With Directional Beams: Design, Implementation, and Validation by Spandan Bisoyi, Pasupuleti Muralimohan, Harish Kumar Dureppagari, Pavan Reddy Manne, Kiran Kuchi

“…To address this, we introduced a fair scheduling algorithm alongside user pairing, which reduces the simultaneous number of paired users to 7 with QPSK modulation within the 30&#x00B0; sector, ensuring equal pairing opportunities for all users. Additionally, to support higher modulation scheme we modified the correlation threshold and achieved a pairing of 4 users with 16QAM modulation, and 3 users with 64QAM modulation scheme. …”
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Knowledge, Attitude, and Associated Factors towards Nonpharmacological Pain Management among Nurses Working at Amhara Region Comprehensive Specialized Hospitals, Ethiopia by Esayas Alemshet Tekletsadik, Abebaw Alemayehu Desta, Belayneh Shetie Workneh

“…It is better to give attention to reviewing the nursing curriculum, achieving a standardized nurse-to-patient ratio, recruiting additional nurses, training, and upgrading nurses with continuing education.…”
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Effects of using different levels of dietary chitosan on some immune indices and antioxidant defense system in Vannamei shrimp, Litopenaeus vannamei by Saeed Dayani, Valiallah Jafari, Roghayeh Safari, Seyed Hossein Hoseinifar

“…For this purpose, diets supplemented with feed additives have won the interest of researchers who are concerned with the aquaculture field, the most important of which is chitosan, a cationic biopolymer, derived from the alkaline deacetylation of chitin; a natural polymer found in the exoskeletons of insects, crustaceans and fungal cell walls. …”
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A preoperative predictive model based on multi-modal features to predict pathological complete response after neoadjuvant chemoimmunotherapy in esophageal cancer patients by Yana Qi, Yanran Hu, Chengting Lin, Ge Song, Liting Shi, Hui Zhu

“…Shapley values were also utilized to explain the prediction model.ResultsThe predictive capability of the multi-modality model in predicting pCR yielded an area under the curve (AUC) of 0.89 (95% confidence interval [CI], 0.75-1.00), outperforming the radiomics model (AUC 0.70 [95% CI 0.54-0.85]), pathomics model (AUC 0.77 [95% CI 0.53-1.00]), and clinical model (AUC 0.63 [95% CI 0.46-0.80]). Additionally, both the calibration plot and DCA curves support the clinical utility of the integrated multi-modality model.ConclusionsThe combined multi-modality model we propose can better predict the pCR status of esophageal cancer and help inform clinical treatment decisions.…”
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Analysis of argument structure constructions in the large language model BERT by Pegah Ramezani, Pegah Ramezani, Achim Schilling, Achim Schilling, Patrick Krauss, Patrick Krauss

“…SUBJ, CLS, and SEP tokens did not show significant FDR scores. Our study underscores the complex, layered processing of linguistic constructions in BERT, revealing both similarities and differences compared to recurrent models like LSTMs. …”
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