A multigene phylogeny toward a new phylogenetic classification of Leotiomycetes by Peter R. Johnston, Luis Quijada, Christopher A. Smith, Hans-Otto Baral, Tsuyoshi Hosoya, Christiane Baschien, Kadri Pärtel, Wen-Ying Zhuang, Danny Haelewaters, Duckchul Park, Steffen Carl, Francesc López-Giráldez, Zheng Wang, Jeffrey P. Townsend

“…To test the statistical support for the deepest branches in the phylogeny, an additional phylogeny based on 3156 genes from 51 selected genomes is also presented. …”
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Acceptance of artificial intelligence clinical assistant decision support system to prevent and control venous thromboembolism among healthcare workers: an extend Unified Theory of... by Jingxian Wang, Yun Zhou, Yun Zhou, Kai Tan, Zhigang Yu, You Li

“…Social influence did not influence nurses’ behavioral intention (β = 0.06, p = 0.376), but negatively influenced clinicians’ behavioral intention in the model (β = −0.19, P < 0.001). …”
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Decoding MexB efflux pump genes: structural, molecular, and phylogenetic analysis of multidrug-resistant and extensively drug-resistant Pseudomonas aeruginosa by Muhammad Bilal Habib, Naseer Ali Shah, Afreenish Amir, Huda Ahmed Alghamdi, Muhammad Haseeb Tariq, Kiran Nisa, Mariam Ammoun

“…The presence of an active efflux-pump system was indicated by the MexB genes found in most of the resistant isolates (p<0.05). Following addition of efflux pump inhibitor carbonyl cyanide m-chlorophenyl hydrazone (CCCP), a significant decrease (p<0.05) in MIC was observed in resistance, that revealed the presence of active efflux pump system. …”
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Extracorporeal Hemadsorption versus Glucocorticoids during Cardiopulmonary Bypass: A Prospective, Randomized, Controlled Trial by Gordana Taleska Stupica, Maja Sostaric, Marija Bozhinovska, Lea Rupert, Zoran Bosnic, Ales Jerin, Alojz Ihan, Tomislav Klokocovnik, Matej Podbregar

“…Proinflammatory (TNF-α, IL-1β, IL-6, and IL-8) and anti-inflammatory (IL-10) cytokines which complement C5a, CD64, and CD163 expression by immune cells were analyzed within the first five postoperative days, in addition to hemodynamic and clinical outcome parameters. …”
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CH4-C3H8 mixed gas hydrates formation in marine mud and foraminifera-rich sand from the South China Sea: an experimental approach by Peixiao Mao, Peixiao Mao, Peixiao Mao, Judith M. Schicks, Mengdi Pan, Mengdi Pan, Nengyou Wu, Nengyou Wu

“…CH4-C3H8 mixed gas hydrates are widely distributed in deep-sea weakly-consolidated muddy sediments of the South China Sea, enriched with biological clastics like foraminifera-rich sand. …”
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The Gut Microbiota and Its Relevance to Peripheral Lymphocyte Subpopulations and Cytokines in Patients with Rheumatoid Arthritis by Yuan Li, Sheng-Xiao Zhang, Xu-Fang Yin, Ming-Xing Zhang, Jun Qiao, Xiao-Hong Xin, Min-Jing Chang, Chong Gao, Ya-Feng Li, Xiao-Feng Li

“…There was increased relative abundance of genus Clostridium_XlVa as well as genus Blautia, more abundance of Ruminococcus2 in patients with lower levels of T, B, CD4+T, and Tregs. In addition, the relative abundances of Pelagibacterium, Oxalobacter, ClostridiumXlVb, and ClostridiumXVIII were correlated with cytokines. …”
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REDD1 mediates HDM-induced nuclear-cytoplasmic translocation and release of IL-33 in airway epithelial cells by downregulating Nrf2 by Tian Luo, Wentao Ji, Yuxin Gong, Lichang Chen, Chao Liu, Dandan Zhang, Xi Li, Yanhua Lv

“…In vitro, 24-hour exposure to HDM induced a notable nuclear-to-cytoplasmic translocation of IL-33 and increased its levels in the culture medium of 16HBE cells. In addition, HDM treatment significantly upregulated the expression of both REDD1 and Nrf2. …”
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Salicylic acid confers cadmium tolerance in wheat by regulating photosynthesis, yield and ionic homeostasis by Umer Hayat, Kaleem ul din, Muhammad Ahmad, Usman Zulfiqar, Maryium Sajjad, Muhammad Faisal Maqsood, Walid Soufan, P. V. Vara Prasad, Ivica Djalovic

“…However, the foliar applications of SA in Cd-stressed plants significantly improved the plant growth and yield attributes, relative water content, gas exchange attributes, and chlorophyll content in both wheat varieties as compared to control-no SA applied. In addition, chlorophyll fluorescence and nutrient uptake were also improved under SA applications as compared to control. …”
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The relationship between vision status and its influencing factors among primary and secondary school students: The masking effect of physical activity level and the moderating eff... by Jiyan Xu, Yanjun Li, Siyuan Ma, Shimeng Dai, Weiwei Xu, Mengjiao Sang, Kaijie Feng

“…Parents should avoid having excessive expectations and additional academic burdens on their children and encourage them to actively participate in sports; schools should fully implement the ‘’Double Reduction’’ policy, making myopia prevention and control an important part of health education; communities should carry out publicity work for myopia prevention and control, raising adolescents’ awareness of eye health.…”
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Silver-based plasmonic nanoparticles for biosensor organophosphate pesticides using a single film containing acetylcholinesterase/choline oxidase by D. Hermanto, N. Ismillayli, H. Muliasari, R. Wirawan, S.R. Kamali

“…CONCLUSION: Biosensor measurement outcome aligned with the gas chromatography-mass spectrometry result, which is the accepted standard method for detecting profenofos. Additionally, the proposed biosensor offers several advantages such as ease of use, fast, low-cost, and on-site analysis. …”
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Pirfenidone regulates seizures through the HMGB1/TLR4 axis to improve cognitive functions and modulate oxidative stress and neurotransmitters in PTZ-induced kindling in mice by Mansi Dahalia, Sparsh Gupta, Haya Majid, Divya Vohora, Nidhi

“…Histopathological analysis revealed that pirfenidone ameliorated cellular disintegration and neuronal damage in the hippocampus and cortex.ConclusionPirfenidone shows potential as an anticonvulsant, anti-inflammatory, hepatoprotective, and neuroprotective agent, with additional benefits in improving cognition and oxidative stress profiles in epilepsy treatment. …”
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The pattern of antibiotic utilisation among intensive care unit patients hospitalised in a Gauteng (South African) provincial tertiary hospital: Comparing findings before and durin... by L Spinickum, Z Booth, S Leigh-de Rapper

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The role of sport in research and development in Switzerland - An overview by Hippolyt Kempf, Gübeli Cornell, Christelle Ganné-Chedeville, Solange Emmenegger

“…Sport is negligible in these statistics. This is at odds with the pressure to innovate in competitive sport and the economic and social importance of sport. …”
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Profiles and predictors of access to human and veterinary healthcare in multispecies households by Jennifer W. Applebaum, Courtney Dunn, Shelby E. McDonald, Kaylinn Escobar, Erin K. King, Rosalie Corona, Megan K. Mueller

“…For example, the groups with better access were likely to have low financial fragility (Good access/unfair system OR = 4.61, p < 0.001), and those with poorer access were unlikely (Poor access OR = 0.14). Additionally, the groups with better access were less likely to experience discrimination (Good access/fair system OR = 0.58, p < 0.001) and those with poorer access were more likely (Moderate and Poor access both ORs = 1.37, p < 0.001). …”
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Large-Scale Neuronal Network Dysfunction in Diabetic Retinopathy by Xin Huang, Yan Tong, Chen-Xing Qi, Han-Dong Dan, Qin-Qin Deng, Yin Shen

“…Compared to the HC group, DR patients showed significant decreased intranetwork FCs within the basal ganglia network (BGN), visual network (VN), ventral default mode network (vDMN), right executive control network (rECN), salience network (SN), left executive control network (lECN), auditory network (AN), and dorsal default mode network (dDMN). In addition, FNC analysis showed increased VN-BGN, VN-vDMN, VN-dDMN, vDMN-lECN, SN-BGN, lECN-dDMN, and AN-BGN FNCs in the DR group, relative to the HC group. …”
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PC-YOLO11s: A Lightweight and Effective Feature Extraction Method for Small Target Image Detection by Zhou Wang, Yuting Su, Feng Kang, Lijin Wang, Yaohua Lin, Qingshou Wu, Huicheng Li, Zhiling Cai

“…At the same time, in order to reduce unnecessary calculations and lower the complexity of the model, we removed the P5 layer. In addition, we have introduced the coordinate spatial attention mechanism, which can help the network more accurately obtain the spatial and positional features required for small targets, thereby further improving detection accuracy. …”
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Major F plasmid clusters are linked with ColV and pUTI89-like marker genes in bloodstream isolates of Escherichia coli by Cameron J. Reid, Max L. Cummins, Steven P. Djordjevic

“…Plasmids associated with different lineages of ST131 formed additional major clusters, whilst F51:A-:B10 plasmids in ST73 were also common. …”
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Barriers and facilitators of integrated hepatitis B, C, and HIV screening among pregnant mothers and newborns attending maternal and newborn clinics in Koboko District, Uganda: a q... by John Bosco Alege, John Paul Oyore, Rose Clarke Nanyonga, Philippa Musoke, Alloys S. S. Orago

“…Strong team spirit, reducing patient waiting times, and enhancing the incorporation of HBV and HIV into the HMIS2 form are essential steps. Additionally, support from implementing partners like IDI, is pivotal. …”
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Assessment of healthcare providers’ knowledge, attitude, and practice toward medical research in southwest Saudi Arabia: a cross-sectional study by Hadi Al Sulayyim, Ali Alrashah, Ali Al Mansour, Fahad Al Sleem, Yahya Alfaifi, Mansour Alyami, Ali Alkhudeer, Hassan Al Hutaylah, Yousef Allajam, Abdullah Alkhurais, Noura Alfaifi, Mansour Majrshi, Abdullah Alsulayyim

“…Abstract Background Medical research plays a crucial role in advancing the treatment and prevention of diseases, in addition to enhancing public health. Objectives This study aims to assess knowledge, attitude, and practice (KAP) of healthcare providers (HCPs) in relation to medical research, identify motivating factors and barriers that prevent them from conducting research, and identify associated factors with good knowledge, practice and positive attitude. …”
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Pharmacokinetic Evaluation of Neutral Sphinghomyelinase2 (nSMase2) Inhibitor Prodrugs in Mice and Dogs by Arina Ranjit, Chae Bin Lee, Lukáš Tenora, Vijaya Saradhi Mettu, Arindom Pal, Jesse Alt, Barbara S. Slusher, Rana Rais

“…<b>Methods:</b> The scaleup of selected prodrugs was completed and two additional valine- ester based prodrugs were synthesized. …”
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