Development of an easy non‐destructive particle isolation protocol for quality control of red blood cell concentrates by Marine Ghodsi, Anne‐Sophie Cloos, Anaïs Lotens, Marine De Bueger, Patrick Van Der Smissen, Patrick Henriet, Nicolas Cellier, Christophe E. Pierreux, Tomé Najdovski, Donatienne Tyteca

“…Abstract The extracellular vesicle release in red blood cell concentrates reflects progressive accumulation of storage lesions and could represent a new measure to be implemented routinely in blood centres in addition to haemolysis. Nevertheless, there is currently no standardized isolation protocol. …”
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Equalizer Design: HBOA-DE-trained radial basis function neural networks by Santosh Kumar Das, Satya Ranjan Pattanaik, Pradyumna Kumar Mohapatra, Saroja Kumar Rout, Abdulaziz S. Almazyad, Muhammed Basheer Jasser, Guojiang Xiong, Ali Wagdy Mohamed

“…The proposed algorithm is compared with well-known algorithms in terms of Mean Square Error (MSE) and Bit Error Rate (BER). Additionally, the algorithm has been tested against a situation in burst error and evaluated via bit error probability (BEP) to establish its robustness and performance. …”
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Classifying problematic gaming using a latent profile approach based on personality traits in Chinese young adolescent by Jingyue Hao, Zhenjiang Liao, Qiuping Huang, Xinxin Chen, Shuhong Lin, Yongyan Shi, Yifan Li, Yin Tang, Xuhao Wang, Hongxian Shen

“…Conclusion Traits such as low neuroticism and high conscientiousness serve as protective factors against gaming addiction, while being unmarried or an only child provides additional safeguards. Conversely, increased time and financial investment in gaming activities are associated with a heightened risk of addiction. …”
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Multiple patterns of EEG parameters and their role in the prediction of patients with prolonged disorders of consciousness by Hui Li, Hui Li, Hui Li, Linghui Dong, Linghui Dong, Linghui Dong, Wenlong Su, Wenlong Su, Ying Liu, Ying Liu, Zhiqing Tang, Zhiqing Tang, Xingxing Liao, Xingxing Liao, Junzi Long, Junzi Long, Xiaonian Zhang, Xinting Sun, Hao Zhang, Hao Zhang, Hao Zhang, Hao Zhang

“…A combination of machine learning and SHapley Additive exPlanations (SHAP) were used to develop predictive model and interpret the results.ResultsThe results indicated significant abnormalities in low-frequency spectral power, microstate parameters, and amplitudes of MMN and P3a in MCS and UWS. …”
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Transcriptome Analysis Reveals the Molecular Mechanism of PLIN1 in Goose Hierarchical and Pre-Hierarchical Follicle Granulosa Cells by Hua He, Yueyue Lin, Xi Zhang, Hengli Xie, Zhujun Wang, Shenqiang Hu, Liang Li, Hehe Liu, Chunchun Han, Lu Xia, Jiwei Hu, Jiwen Wang, Lin Liao, Xin Yuan

“…Based on these findings, we hypothesize that <i>PLIN1</i> overexpression may promote granulosa cell proliferation and apoptosis by activating the TGF-β signaling pathway in goose follicular GCs. Additionally, nine potential candidate genes were identified: <i>PPARγ</i>, <i>MGLL</i>, <i>PTEN</i>, <i>BAMBI</i>, <i>BMPR2</i>, <i>JUN</i>, <i>FST</i>, <i>ACSF3</i>, and <i>ACSL4</i>. …”
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Genomic characterization of Achromobacter genogroup 20 and identification of a potential species-specific marker by Mariana Papalia, Rocio Stucchi, Valeria Alexander, Liliana Clara, Mariángeles Visus, Gabriel Gutkind, Marcela Radice

“…In silico analysis found OXA-1238 variants in three additional Achromobacter spp. genomes, with 97% identity. …”
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ROR1 CAR-T cells and ferroptosis inducers orchestrate tumor ferroptosis via PC-PUFA2 by Dan Li, Wenjie Zhang, Ruiheng Wang, Shufeng Xie, Yixin Wang, Wanxin Guo, Zixuan Huang, Chaoqun Lu, Liang Shan, Han Liu, Lifang Ma, Xumin Hou, Zhenshu Xu, Jiayi Wang

“…Methods RNA-seq data and immunofluorescence analysis of relapsed NSCLC patient samples were used to explore ROR1 expression. In addition, ROR1-targeting CAR-T cells were developed to assess cytotoxic activity against ROR1+ tumor cells, and the effect of cytokine stimulation on their efficacy was evaluated. …”
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N-Butyl-2-Cyanoacrylate Adhesive Versus Absorbable Tacks in Laparoscopic Groin Hernia Repair: A Multicenter Randomized Clinical Trial by Clayton C. Petro, MD, Benjamin K. Poulose, MD, Michael J. Rosen, MD, Alfredo M. Carbonell, II, DO, Adel G. El-Ghazzawy, MD, Jeremy A. Warren, MD, Emanuele Lo Menzo, MD, Ajita S. Prabhu, MD, David M. Krpata, MD, Samuel Szomstein, MD, Vimal Narula, MD, Crystal F. Totten, MD, Kelly R. Haisley, MD, Andrew C. Bernard, MD, Henrik O. Berdel, MD, Jessica K. Reynolds, MD, Zachary D. Warriner, MD, John S. Roth, MD

“…There were no differences in secondary outcomes including recurrence, successful use of each device to fixate the mesh and peritoneum, quality of life, and additional VAS pain scores. Rates of adverse and serious AEs were also comparable. …”
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Essential core competencies for scope of practice of paediatric oncology nurses in Latin America: a scoping review protocol by Luís Carlos Lopes-Júnior, Regina Aparecida Garcia Lima, Soad Fuentes-Alabi, Edmara Bazoni Soares Maia, Karina de Cássia Braga Ribeiro, Courtney E Sullivan, Monnie Abraham, Lorena Segovia Weber, Liliana Vásquez Ponce

“…MEDLINE/PubMed, Cochrane Library, Embase, CINAHL, Web of Science, Scopus, Science Direct and Latin American and Caribbean Health Sciences Literature, plus additional sources: The ProQuest Dissertation &amp; Theses Global, The British Library, Google Scholar, medRXiv, ClinicalTrials.gov and WHO-ICTRP will be searched. …”
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Breeding Performances of the European Blackbird (Turdus merula) in Morocco: Habitat Selection, Breeding Phenology, and Breeding Success by Abderahim El Hassani, Ismail Mansouri, Wafae Squalli, Abdelbari El Agy, Amine Assouguem, Kenza Bouayad, Abdellah Markou, Mohamed Mounir, Hamid Achiban, Mohamed Dakki, Lahsen El Ghadraoui

“…Blackbird nests were cup-shaped with medium size dimensions and built from twigs, including dry leaves, stems, and roots walled by the mud. …”
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Effect of electroacupuncture on vascular remodeling in rats with cerebral ischemia by regulating irisin based on VEGF/Akt/eNOS signaling pathway by Lu Cao, Wenchao Ding, Yashuo Feng, Chong Guan, Li Liu, Hongyu Xie, Kewei Yu, Dongyan Xu, Lijuan Zhao, Xuan Sha, Xiaoman Deng, Santian Wu, Yangrui Wang, Yi Wu, Tingting Zhang, Nianhong Wang

“…Results: The number of FNDC5-positive neurons, fluorescence intensity, and irisin expression reached their maximum increase after 7 days of EA treatment. In addition, the EA group exhibited a significant reduction in cerebral infarct volume and impairment of neurobehavioral function, an increase in cerebral blood flow and microvascular diameter on the ischemic side, and significantly higher expression levels of FNDC5, brain-derived neurotrophic factor (BDNF), vascular endothelial growth factor (VEGF), protein kinase B (Akt), and endothelial nitric oxide synthase (eNOS). …”
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Human soft tissue sarcomas harbor an intratumoral viral microbiome which is linked with natural killer cell infiltrate and prognosis by William J Murphy, Robert J Canter, Nikhil Joshi, Sean J Judge, Morgan A Darrow, Steve W Thorpe, Alicia A Gingrich, Lauren M Perry, Sylvia M Cruz, Kara T Kleber, Louis B Jones, Ugur N Basmaci, Matthew L Settles, Blythe P Durbin-Johnson, Arta Monir Monjazeb, Janai Carr-Ascher, Jonathan A Eisen

“…Our data suggest that the STS tumor microbiome has prognostic significance with viral relative abundance associated with NK infiltration and oncologic outcome. Additional studies are warranted to further assess the clinical impact of these findings.…”
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Purinergic Signaling Pathway in Human Olfactory Neuronal Precursor Cells by Héctor Solís-Chagoyán, Edgar Flores-Soto, Marcela Valdés-Tovar, Montserrat G. Cercós, Eduardo Calixto, Luis M. Montaño, Carlos Barajas-López, Bettina Sommer, Arnoldo Aquino-Gálvez, Citlali Trueta, Gloria A. Benítez-King

“…The clonal culture was enriched with SOX2 and OCT3/4 transcription factors; additionally, the proportion of nestin-immunopositive cells, the proliferation capability, and functionality of differentiated progeny remained unaltered through the long-term clonal culture. hONPC expressed P2X receptor subtypes 1, 3-5, and 7, as well as P2Y2, 4, 6, and 11; ATP induced both exocytosis and a transient [Ca2+]i increase predominantly by activation of metabotropic P2Y receptors. …”
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Arbovirus exposure and subclinical myocardial dysfunction in an Indigenous population in Northeast Brazil: a cross-sectional study by Jandir Mendonça Nicacio, Carlos Dornels Freire de Souza, Ricardo Khouri, Vanessa Cardoso Pereira, Rodrigo Feliciano do Carmo, Pedro Vinícius Amorim de Medeiros Patriota, Sávio Luiz Pereira Nunes, Jeová Cordeiro de Morais Júnior, Manoel Barral-Netto, João Augusto Costa Lima, Anderson da Costa Armstrong

“…We assessed the seroprevalence of dengue, chikungunya, and Zika viruses in the Fulni-ô Indigenous community, the less urbanized and most traditional group. Additionally, we explored the relationship between these viruses and subclinical heart disease, assessed by speckle-tracking echocardiography-derived GLS. …”
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Activity-based chemical proteomics reveals caffeic acid ameliorates pentylenetetrazol-induced seizures by covalently targeting aconitate decarboxylase 1 by Guanjun Li, Ling Huang, Di Gu, Peili Wang, Letai Yi, Wenhua Kuang, Ying Zhang, Junzhe Zhang, Dandan Liu, Qiaoli Shi, Huan Tang, Jichao Sun, Guohua Zeng, Xin Peng, Jigang Wang

“…Methods In this study, we established pentylenetetrazol-induced acute and kindling models of seizures. Additionally, a BV2 microglial cellular inflammation model was established by lipopolysaccharide stimulation. …”
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Laser Vaporization of Intracoronary Thrombus and Identifying Plaque Morphology in ST-Segment Elevation Myocardial Infarction as Assessed by Optical Coherence Tomography by Yuki Yamanaka, Yoshihisa Shimada, Daisuke Tonomura, Kazunori Terashita, Tatsuya Suzuki, Kentaro Yano, Satoshi Nishiura, Masataka Yoshida, Takao Tsuchida, Hitoshi Fukumoto

“…Plaque rupture was identified by OCT in only 22 cases (23.9%) after MT, but was distinguishable in 36 additional cases after ELCA (total: 58 cases; 63.0%). …”
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Cochlear implantation in vestibular schwannoma: A game changer? A narrative review by Luis Lassaletta, Miryam Calvino, Isabel Sánchez-Cuadrado, José Manuel Morales-Puebla, Javier Gavilán

“…The variability of the outcomes still precludes routine CI in VS with normal contralateral hearing. In addition to VS undergoing surgical resection and CI placement, some observed and irradiated VS cases also benefit from a CI. …”
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Relationship Between Perilesional Skin Condition and Survival in Terminally Ill Patients with Pressure Ulcers by María Isabel Pastor-Orduña, Federico Palomar-Llatas, David Palomar-Albert, María Teresa Murillo-Llorente, Ignacio Ventura, Francisco Tomás-Aguirre, Marcelino Pérez-Bermejo

“…These findings support the implementation of therapeutic interventions based on a structured perilesional tissue assessment to improve quality of life and prolong survival in terminally ill patients. In addition, a positive correlation was found between Barthel Score and survival, suggesting that patients with greater functional independence have a longer life expectancy. …”
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Factorial invariance of the generalized anxiety disorder scale (GAD-7) in Latin America and the Caribbean by Norman López, Norman López, Juan-Carlos Coronado, Daniela Ripoll-Córdoba, Nicole Caldichoury, César Quispe-Ayala, Breiner Morales-Asencio, Raúl Quincho-Apumayta, Cesar Castellanos, Juan Martínez, Juan Cárdenas-Valverde, Luis Mario Castellanos-Alvarenga, David Salazar, Irina Flores-Poma, Jorge Herrera-Pino, Wendy Bada, Yuliana Flórez, Karen Alcos-Flores, Boris Zurita-Cueva, Elsa Muñoz Romero, Cristian Romo, Regulo Antezana, Claudio Avila Saldaña, Pascual A. Gargiulo

“…The model fit indices were adequate (RMSEA = 0.062; CFI = 0.997; TLI = 0.995; SRMR = 0.017; p &lt; 0.001), and the factor loadings for each item were satisfactory (&gt; 0.70). Additionally, the factor structure showed measurement invariance between genders and countries, with adequate fit indices at all levels (configural, metric, scalar, and strict), suggesting that the measurements are equivalent in both contexts. …”
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Association between SPISE and NAFLD in patients with type 2 diabetes by Hongyan Zhao, Hongyan Zhao, Baolan Ji, Xin Wang, Shuwei Shi, Shuwei Shi, Jie Sheng, Jie Sheng, Xuan Ma, Xuan Ma, Bo Ban, Guanqi Gao

“…SPISE was calculated based on high density lipoprotein-cholesterol (HDL-c), triglycerides (TG), and body mass index (BMI). Participants were categorized into NAFLD and non-NAFLD groups based on the results of ultrasonographic diagnosis. …”
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