The association between folic acid supplementation, maternal folate during pregnancy and intelligence development in infants: a prospective cohort study by Shaokang Wang, Jie Wei, Di Wang, Li Hua, Da Pan, Lingmeng Fu, Jin Yang, Guiju Sun

“…Conclusion: In conclusion, folic acid supplementation in the pre-pregnancy supplementation group and the post-pregnancy supplementation group may be not associated with infant mental development. In addition, maternal folate and homocysteine may be related to the intellectual development of infants. …”
Get full text

Organizational readiness for change towards implementing a sepsis survivor hospital to home transition-in-care protocol by Elaine Sang, Elaine Sang, Ryan Quinn, Michael A. Stawnychy, Michael A. Stawnychy, Michael A. Stawnychy, Michael A. Stawnychy, Jiyoun Song, Jiyoun Song, Jiyoun Song, Karen B. Hirschman, Karen B. Hirschman, Karen B. Hirschman, Sang Bin You, Sang Bin You, Katherine S. Pitcher, Katherine S. Pitcher, Nancy A. Hodgson, Nancy A. Hodgson, Nancy A. Hodgson, Patrik Garren, Melissa O'Connor, Sungho Oh, Sungho Oh, Kathryn H. Bowles, Kathryn H. Bowles, Kathryn H. Bowles, Kathryn H. Bowles

“…Future research should confirm, expand, and examine underlying factors related to these findings with a larger and more diverse sample. Additional studies may assess the predictive validity of ORIC towards implementation success.…”
Get full text

Event-related theta synchronization over sensorimotor areas differs between younger and older adults and is related to bimanual motor control by Andreas Wulff-Abramsson, Ana Zvornik, Keenie Ayla Andersen, Yan Yang, Mikael Novén, Jesper Lundbye-Jensen, Leo Tomasevic, Anke Ninija Karabanov

“…Older adults also displayed lower theta ERS across conditions. Additionally, older adults were not able to modulate theta expression based on whether a force change was initiated to a novel target or back to baseline. …”
Get full text

Malva neglecta essential oil: A promising approach for bio-preserving mayonnaise and assessing variable correlations through principal component analysis and heat map by Amin Abbasi, Hedayat Hosseini, Hadi Pourjafar, Samaneh Moradi, Saeedeh Shojaee-Aliabadi

“…Consumers increasingly regard plant-derived biocompounds as a safe alternative to synthetic additives. To increase shelf life and enhance safety status, this study sought to determine how Malva neglecta essential oil (MNEO) might affect microbiological and chemical changes in mayonnaise samples at 4 °C. …”
Get full text

Second order slip micropolar MHD hybrid nanofluid flow over a stretching surface with uniform heat source and activation energy: Numerical computational approach by Syed Arshad Abas, Hakeem Ullah, Mehreen Fiza, Ali Akgul, Aasim Ullah Jan, Magda Abd El-Rahman, Seham M. Al-Mekhlafi

“…Findings: The results reveal that the inclusion of slip boundary conditions significantly influences the flow dynamics, reducing skin friction by 4.9 % and 10.4 % with increasing magnetic and material parameters, respectively, but enhancing it with a higher slip factor by 18.88 %. Additionally, an increased volume fraction of nanoparticles elevates the heat transfer rate by 6.3 % while diminishing the Sherwood number by 2.6 %, showcasing the thermal enhancement capabilities of the hybrid nanofluid. …”
Get full text

Corticomuscular Coupling Alterations During Elbow Isometric Contraction Correlated With Clinical Scores: An fNIRS-sEMG Study in Stroke Survivors by Xiaohan Wang, Weidong Li, Rong Song, Di Ao, Huijing Hu, Le Li

“…The effective connectivity from the ipsilateral motor cortex to the contralateral motor cortex during elbow movements in the affected group showed a meaningful positive association with the Fugl-Meyer Assessment (FMA) scale. Additionally, the transfer entropy from the contralateral motor cortex to the agonist muscle in the affected group demonstrated a significant positive correlation with the FMA scale at 70% MVC during elbow flexion. …”
Get full text

Clinical validation and optimization of machine learning models for early prediction of sepsis by Xi Liu, Meiyi Li, Xu Liu, Yuting Luo, Dong Yang, Hui Ouyang, Jiaoling He, Jinyu Xia, Fei Xiao, Fei Xiao, Fei Xiao

“…The data of another cohort of 2,286 patients between October 1, 2020 and April 1, 2022 were used to validate the performance of the model performing best in the in the internal validation set. Shapley additive explanations (SHAP) method was applied to evaluate feature importance and explain the predictions of this model.ResultsOf the five machine learning models developed, the RF model demonstrated the best performance in terms of AUC (0.818), F1 value (0.38), and sensitivity (0.746). …”
Get full text

Impact of prior CAR T-cell therapy on mosunetuzumab efficacy in patients with relapsed or refractory B-cell lymphomas by Elise A. Chong, Elicia Penuel, Ellen B. Napier, Rachel K. Lundberg, Lihua E. Budde, Mazyar Shadman, Matthew J. Matasar, Nancy L. Bartlett, Ian W. Flinn, Francesc Bosch, Keith Fay, Andre Goy, Anita Kumar, Loretta J. Nastoupil, Michael C. Wei, Mei Wu, Shen Yin, Joseph A. Fraietta, Emeline R. Chong, Stephen J. Schuster

“…The median time from CAR-T to mosunetuzumab was significantly longer for responding than for nonresponding patients (P = .006, unadjusted for multiple comparisons). Most patients (20/30) did not receive intervening therapy between CAR-T administration and mosunetuzumab. …”
Get full text

Peptide P2 targeting Vibrio parahaemolyticus PirB toxins blocks the cytotoxic effects to shrimp Litopenaeus vannamei by Xin Zhang, Ting Chen, Chunhua Ren, Yanhong Wang, Xiao Jiang, Jiasheng Huang, Bo Ma, Boxiang Zhu, Jiayue Yin, Chaoqun Hu, Peng Luo

“…PirB is the main virulence factor of acute hepatopancreatic necrosis disease (AHPND) which induced the sloughing of hepatopancreatic cells and shrimp death. In addition, Litopenaeus vannamei aminopeptidase N (Lv-APN) is reported to be a functional receptor that mediates the pathogenicity by VpAHPND. …”
Get full text

Elevated Serum Levels of the Antiapoptotic Protein Decoy-Receptor 3 Are Associated with Advanced Liver Disease by Giorgos Bamias, Michalis Gizis, Ioanna Delladetsima, Eyfrosyni Laoudi, Spyros I. Siakavellas, Ioannis Koutsounas, Garyfallia Kaltsa, John Vlachogiannakos, Irene Vafiadis-Zouboulis, George L. Daikos, George V. Papatheodoridis, Spiros D. Ladas

“…Results. sDcR3 levels were significantly higher in patients with CVH than in controls (P<0.01). sDcR3 levels were elevated in DC and HCC, being significantly higher compared not only to controls (P<0.001 for both) but to CVH patients as well (P<0.001 for both). In addition, DcR3 protein was detected in large quantities in the ascitic fluid of cirrhotics. …”
Get full text

Liraglutide alleviates high-fat diet-induced kidney injury in mice by regulating the CaMKKβ/AMPK pathway by Yingli Xuan, Ting-ting Ding, Xiao-lei Mao, Shiqing Pang, Ruibin He, Li Qin, Jiang zi Yuan

“…Objective Liraglutide, a glucagon-like peptide-1 receptor agonist, has been shown to regulate blood sugar and control body weight, but its ability to treat obesity-related nephropathy has been poorly studied. …”
Get full text

Design, implementation and evaluation of OSPE exam to evaluate the competence of occupational health and safety engineering students by Samira Rahimnejad, Kamaladdin Abedi, Farough Mohammadian, Ebrahim Darvishi, Ebrahim Mohammadi, Farzaneh Zarei, Madjid Shafiiyan

“…Students' satisfaction with the exam was average. In addition, by examining the results of qualitative data, two classes and several subclasses were obtained. …”
Get full text

Dosimetry of automatic non-coplanar volumetric-modulated arc therapy for nasopharyngeal carcinoma by Kaiqiang Chen, Jihong Chen, Yanming Cheng, Danni Hong, Cairong Hu, Penggang Bai, Jinyong Lin, Yang Yang, Xiuchun Zhang

“…Moreover, the HA plans had better sparing, particularly for the optic chiasm, optic nerves, and parotid glands (P ​< ​0.05), while no statistically significant differences were observed for other critical structures such as the brainstem, spinal cord, and temporal lobes (P ​> ​0.05). Additionally, the average beam-on time for the HA plans (252 ​s) was shorter than that of the TOMO plans (326 ​s, P ​< ​0.05). …”
Get full text

LRP1 involvement in FHIT-regulated HER2 signaling in non-small cell lung cancer by Théophile Ponchel, Emma Loeffler, Julien Ancel, Audrey Brisebarre, Nathalie Lalun, Véronique Dalstein, Anne Durlach, Gaëtan Deslée, Stéphane Dedieu, Myriam Polette, Béatrice Nawrocki-Raby

“…In addition, we found that the induction of vimentin upon FHIT inactivation was counteracted by LRP1 silencing. …”
Get full text

Comparison of microstructures and magnetic properties of Tb-Pr-Cu-Al and Tb-Nd-Cu-Al grain boundary diffused Nd-Fe-B magnets by Zixiang Mo, Qingzheng Jiang, Mengping Kan, Jianming Li, Hang Wang

“…Low melting alloys containing heavy rare earth element Tb have been widely used for grain boundary diffusion (GBD) to increase the coercivity (Hcj) of sintered Nd-Fe-B magnets. The addition of Pr has been demonstrated to further enhance the coercivity for Tb-diffused magnets. …”
Get full text

Tumor CEMIP drives immune evasion of colorectal cancer via MHC-I internalization and degradation by Ying Zhu, Jiao Li, Tao Zhang, Lei Zhao, Min Jin, Jinghua Ren, Jing Tang, Haihong Wang, Zhenyu Lin, Qing Liang, Ruiqi Li, Biying Zhang, Qingling Hua, Guojie Xu, Jiayuan Chen, Lanqing Wang, Dejun Zhang, Dandan Yu

“…The intracellular trafficking of MHC-I was revealed by an immunofluorescent technique. In addition, the effect of CEMIP on tumor growth and the antitumor efficacy of targeting CEMIP in combination with ICB therapy were evaluated in murine models of colorectal cancer.Results We reported that CEMIP specifically downregulated the expression of MHC-I on the surface of murine and human colon cancer cells, hindering the cytotoxicity of CD8+ T cells. …”
Get full text

Long-term smoking contributes to aging frailty and inflammatory response by Huijin Hou, Yidi Chai, Ting Zhang, Yue Liang, Lan Huang, Xu Cao, Shufang Liang

“…Fifteen-month-old C57BL/6J mice were exposed to smoke from two burning cigarettes for 15 minutes in a whole-body chamber. This exposure occurred 4, 6, and 8 times daily for 30 days, representing low, medium, and high smoking dosages, respectively. …”
Get full text

Information Security and Artificial Intelligence&#x2013;Assisted Diagnosis in an Internet of Medical Thing System (IoMTS) by Pi-Yun Chen, Yu-Cheng Cheng, Zi-Heng Zhong, Feng-Zhou Zhang, Neng-Sheng Pai, Chien-Ming Li, Chia-Hung Lin

“…Here, a classifier based on a convolutional neural network (CNN) is used for AI- assisted breast tumor diagnosis. In addition, for biosignal infosecurity, raw data were collected from a radar millimeter-wave (mm-Wave) sensing firmware for detecting vital signs. …”
Get full text

HDL Particle Size and Functionality Comparison between Patients with and without Confirmed Acute Myocardial Infarction by Raissa de Miranda Teixeira, Nicole Cruz de Sá, Ana Paula Caires dos Santos, Vanessa Rocha Anjos e Silva, Elaine Christine de Magalhães Cabral Albuquerque, Luiz Claudio Lemos Correia, Ricardo David Couto

“…The study groups consisted of patients from both sexes, older than 35 years, presented to the Hospital São Rafael (HSR) initially with AMI clinical symptoms. In addition, 40 nonischemic control patients (CPs), without AMI symptomatology, and according to previous inclusion criteria, were selected for convenience in an outpatient care unit. …”
Get full text

Development and validation of a prognostic prediction model for elderly gastric cancer patients based on oxidative stress biochemical markers by Xing-Qi Zhang, Ze-Ning Huang, Ju Wu, Chang-Yue Zheng, Xiao-Dong Liu, Ying-Qi Huang, Qi-Yue Chen, Ping Li, Jian-Wei Xie, Chao-Hui Zheng, Jian-Xian Lin, Yan-Bing Zhou, Chang-Ming Huang

“…Predictive models for five-year overall survival (OS) were constructed using random forest (RF), decision tree (DT), and support vector machine (SVM) methods, and validated using area under the curve (AUC) and calibration plots. The SHapley Additive exPlanations (SHAP) method was used for model interpretation. …”
Get full text