Celastrol boosts fluconazole efficacy against vaginal candidiasis: in vitro and in vivo evidence by Fatma Al-zahraa A. Yehia, Hisham A Abbas, Tarek M. Ibrahim, Basem Mansour, Zuhier A. Awan, Mohammed W. Al-Rabia, Wesam H. Abdulaal, Mustafa Adnan Zeyadi, Solomon Z. Okbazghi, Tarek S. Ibrahim, Wael A. H. Hegazy, Salwa E. Gomaa

“…The rapid emergence of azole resistance in C. albicans, in addition to the limited available antifungal agents, complicates the treatment and emphasizes the urgent need for novel therapeutic options. …”
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Risk factors for moderate disturbance of consciousness in patients with unilateral chronic subdural hematoma by Adrian Liebert, Thomas Eibl, Thomas Bertsch, Hans-Herbert Steiner, Karl-Michael Schebesch, Leonard Ritter

“…In bivariate analysis, radiographic parameters, like greater mean midline shift (p < 0.001), homogenous hypodense type (p = 0.017), additional temporal (p < 0.001) and occipital (p < 0.001) location, “acute-to-chronic” (p = 0.002) and “acute-on-chronic” (p = 0.049) forms were more frequent in group 1. …”
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Overcoming breast cancer cell treatment resistance by optimizing sonodynamic therapy and radiation sensitizers on lncRNA PVT1 and miR-1204 expression by Ali Neshastehriz, Zeinab Hormozi-Moghaddam, Zahra Abedi Kichi, Seyedeh Mona Taheri, Seyed Mohammad Amini, Amir Aghaei

“…Several parameters were evaluated, including reactive oxygen species (ROS) generation and colonization. Additionally, the investigation included assessing the long non-coding RNA (lncRNA) PTV1 with miRNA1204 and related genes using Real-Time PCR. …”
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Thermal Response and Degressive Reaction Study of Oxo-Biodegradable Plastic Products Exposed to Various Degradation Media by S. M. Al-Salem, A. Y. Al-Nasser, M. H. Behbehani, H. H. Sultan, H. J. Karam, M. H. Al-Wadi, A. T. Al-Dhafeeri, Z. Rasheed, M. Al-Foudaree

“…The weight loss measured exceeded 58% after soil burial indicating deterioration under natural environmental stressors. In addition, the thermal characterization campaign executed with the aim of determining the product’s thermal response followed internationally recognised experimental protocols for the determination of thermal stability. …”
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Explore the evolution of winter wheat production and its response to climate change under varying precipitation years in the Loess Plateau of China by Donglin Wang, Yanbin Li, Binbin Zhang, Tengcong Jiang, Siyu Wu, Wenjie Wu, Yi Li, Jianqiang He, Deli Liu, Qinge Dong, Hao Feng

“…The predicted potential yield across three precipitation types showed that wet years exhibited the least fluctuation, while the highest fluctuation were observed in dry years. In particular, the potential winter wheat yield without irrigation in wet years and dry years was 19.84 % higher under SSP245 scenario and 25.22 % higher under SSP585 scenario compared with current conditions. …”
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Probiotic properties of Bacillus licheniformis HN318 and comparison of the effects of its bacterial cells and cultures on growth, immunity and disease resistance of hybrid grouper... by Zhenjie Cao, Qiaoli Yang, Aie Kang, Guotao Wang, Pengshuo Li, Guiping Qiu, Jinge Wang, Chunsheng Liu, Yun Sun, Yun Sun, Yun Sun

“…Hybrid grouper were fed with HN318 cultures and bacterial cells for 8 weeks, and their growth, feed utilization, immune responses, and survival rates upon challenge with Vibrio harveyi were evaluated. Additionally, the expression of immune-related genes was analyzed.ResultsHN318 exhibited high auto-aggregation and gastrointestinal stress resistance, and was found to be safe for use in aquaculture. …”
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Extraction of tree branch skeletons from terrestrial LiDAR point clouds by Jimiao Gao, Liyu Tang, Honglin Su, Jiwei Chen, Yuehui Yuan

“…The results show that the proposed method performs effectively, with overall wood–leaf separation accuracies ranging from 86% to 93%. Additionally, the extracted branch skeleton accurately reflects the natural geometric structure of the trees. …”
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The Sunburst Arc with JWST. III. An Abundance of Direct Chemical Abundances by Brian Welch, T. Emil Rivera-Thorsen, Jane R. Rigby, Taylor A. Hutchison, Grace M. Olivier, Danielle A. Berg, Keren Sharon, Håkon Dahle, M. Riley Owens, Matthew B. Bayliss, Gourav Khullar, John Chisholm, Matthew Hayes, Keunho J. Kim

“…This nitrogen abundance is consistent with enrichment from a population of Wolf–Rayet stars, additional signatures of which are reported in a companion paper. …”
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Comparison of the effectiveness of the helmet interface using flow meters versus the mechanical ventilator for non-invasive ventilation in patients with coronavirus disease 2019. C... by Fernanda dos Reis Ferreira, João Carlos Ferrari Correa, Eduardo Storopoli, Diego Restivo Faria, Karina Cassaro, Natália Feitosa da Hora, Raphael Ritti, Rafael Akira Becker, Simone Dal Corso, Ivan Peres Costa, Luciana Maria Malosá Sampaio

“…Results The study showed no significant difference in intubation rates between the mechanical ventilation (54.3%) and helmet interface with flow meter and positive end-expiratory pressure valve (46.8%) groups (p = 0.37). Additionally, the helmet group had a shorter average duration of use (3.4 ±1.6 days) compared to the mechanical ventilation group (4.0 ±1.9 days). …”
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Topographical mapping of metabolic abnormalities in multiple sclerosis using rapid echo-less 3D-MR spectroscopic imaging at 7T by Eva Niess, Assunta Dal-Bianco, Bernhard Strasser, Fabian Niess, Lukas Hingerl, Beata Bachrata, Stanislav Motyka, Paulus Rommer, Siegfried Trattnig, Wolfgang Bogner

“…Patients with sustained disability (EDSS≥2) showed additional reductions in the posterior parietal lobe. …”
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Real world study on combining local interventions with systemic therapy in unresectable hepatocellular carcinoma by Zhaosong Xue, Ming Yao, Kang Chen, Taiyun Huang, Jianjun Li, Jian Chen, Fei Huang, Yubin Huang, Xiaoyong Cai, Yihe Yan

“…Specifically, patients who exhibited a positive response to triple therapy and fulfilled the criteria for hepatectomy were selected for liver resection. Additionally, investigation assessed association between clinical factors and successful achievement of conversion resection, as well as postoperative recurrence. …”
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Seed Protein Content Estimation with Bench-Top Hyperspectral Imaging and Attentive Convolutional Neural Network Models by Imran Said, Vasit Sagan, Kyle T. Peterson, Haireti Alifu, Abuduwanli Maiwulanjiang, Abby Stylianou, Omar Al Akkad, Supria Sarkar, Noor Al Shakarji

“…Convolutional neural networks (CNNs) with attention mechanisms were proposed along with traditional machine learning models based on feature engineering including Random Forest (RF) and Support Vector Machine (SVM) regression for comparative analysis. Additionally, the CNN classification approach was used to estimate low, medium, and high protein concentrations because this type of classification is more applicable for breeding efforts. …”
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Cognitive Decline in Chronic Migraine with Nonsteroid Anti-inflammation Drug Overuse: A Cross-Sectional Study by Xiaoying Cai, Xiaotian Xu, Aiwu Zhang, Jianwen Lin, Xiaojuan Wang, Wen He, Yannan Fang

“…After adjusting, the risk of cognitive decline was higher in CM compared with control in ACE-R score and language fluency (P<0.05). In addition, CM-MOH sufferers were in higher risk of memory and executive dysfunction (P<0.05). …”
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Improvement of crop production in controlled environment agriculture through breeding by Krishna Bhattarai, Andrew B. Ogden, Sudeep Pandey, Germán V. Sandoya, Ainong Shi, Amol N. Nankar, Murukarthick Jayakodi, Heqiang Huo, Tao Jiang, Pasquale Tripodi, Chris Dardick

“…The expansion of CEA offers promise as a tool for increasing food production in and near urban systems as these systems do not rely on arable agricultural land. In addition, CEA offers resilience to climate instability by growing inside protective structures. …”
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A state of the art review on geotechnical reinforcement with end life tires by M. Shariati, M. Afrazi, H. Kamyab, S. Rouhanifar, E. Toghroli, M. Safa, Sh. Chelliapan, H. Afrazi

“…These insights pave the way for optimizing the performance of sand-rubber mixtures in engineering applications. Additionally, the article delves into modeling approaches that simulate the intricate behavior of these mixtures, facilitating better design and analysis. …”
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Integrative deep immune profiling of the elderly reveals systems-level signatures of aging, sex, smoking, and clinical traitsResearch in context by Lennart Riemann, Rodrigo Gutierrez, Ivan Odak, Joana Barros-Martins, Lennart M. Roesner, Ximena Leon Lara, Christine Falk, Thomas F. Schulz, Gesine Hansen, Thomas Werfel, Reinhold Förster, Berislav Bošnjak, Felix Jenniches, Norman Klopp, Till Robin Lesker, Martin Stangel

“…., HGF and CCL27). Additionally, we identified unique immune signatures associated with smoking, obesity, and diseases such as osteoporosis, heart failure, and gout. …”
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Injury characteristics, mechanisms, and game circumstances in junior community-level Australian football by Indianna L. Franke, Andrea B. Mosler, Brooke E. Patterson, Kay M. Crossley, Patrick Clifton, Steven McPhail, Mark J. Scholes, Matthew G. King

“…The next three most frequently reported body regions were the ankle (n ​= ​29, 8.2 ​%), knee (n ​= ​24, 6.8 ​%), and shoulder (n ​= ​20, 5.6 ​%). …”
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Thermal radiation effects of ternary hybrid nanofluid flow in the activation energy: Numerical computational approach by Hakeem Ullah, Syed Arshad Abas, Mehreen Fiza, Aasim Ullah Jan, Ali Akgul, Magda Abd El-Rahman, Seham M. Al-Mekhlafi

“…Findings: Graphs are used to explain the results in three different kinds of flows: hybrid fluid (Cu+Al2O3/H2O), nanofluid (Cu/H2O), and ternary hybrid fluid (Cu+Al2O3+Ag/H2O). Additionally, the outcomes of the variable parameters are presented and briefly discussed for different flow profiles. …”
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Pacific sailfish (Istiophorus platypterus) in the Eastern Pacific Ocean, association with ocean currents and seasonal effects of upwelling using real-time Argos locations by Chelsea E. Clyde-Brockway, Chelsea E. Clyde-Brockway, Samir Harshad Patel, Gabriela Blanco, Samuel J. Friederichk, Stephen Morreale, Frank V. Paladino, Frank V. Paladino

“…Further research is needed to understand the mechanisms underlying these behavioral adaptations and the ecological factors that contribute to sailfish resilience. Additionally, strengthened protection measures are critical to ensure the conservation of sailfish in Costa Rica, including elimination of all commercial sale.…”
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Ultrasound-guided vs. fluoroscopy-guided percutaneous leverage reduction for severely displaced radial neck fractures in children: a comparative analysis of clinical and radiologic... by Xing Wu, Jingdong Xia, Xiongtao Li, Xiaoliang Chen, Si Wang, Xiantao Shen

“…Reduction quality did not significantly differ between the groups according to the Metaizeau reduction classification (P = 0.130). …”
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