Akkermansia muciniphila and its metabolite propionic acid maintains neuronal mitochondrial division and autophagy homeostasis during Alzheimer’s disease pathologic process via GPR4... by Zifan Wang, Cai Wang, Boyu Yuan, Li Liu, Haoming Zhang, Mingqiang Zhu, Hongxia Chai, Jie Peng, Yanhua Huang, Shuo Zhou, Juxiong Liu, Liyong Wu, Wei Wang

“…In recent years, multiple clinical and animal studies have shown that mitochondrial dysfunction may be involved in the pathogenesis of AD. In addition, short-chain fatty acids (SCFA) produced by intestinal microbiota metabolism have been considered to be important factors affecting central nervous system (CNS) homeostasis. …”
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Knowledge, attitudes and practices regarding pulmonary rehabilitation among patients with chronic respiratory diseases: a cross-sectional questionnaire-based study in a tertiary ho... by Xueli Bai, Yuan Chen, Xiansheng Liu, Lingling Wang, Xiaohong Zhang, Jie Ding, Lin Su, Ruiying Wang, Shuang Wei

“…SEM analysis showed that knowledge directly influenced attitudes (β=−0.538, p<0.001) and both knowledge (β=0.668, p<0.001) and attitudes (β=0.668, p<0.001) significantly influenced practices. Additionally, demographic factors, such as monthly household income, type of chronic respiratory disease, educational level and smoking status were significantly associated with variations in KAP scores (all p<0.05).Conclusions Patients demonstrated poor knowledge, generally positive attitudes, and moderate practices regarding pulmonary rehabilitation. …”
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H. pylori-Associated Gastritis, Gastritis after H. pylori Eradication and H. pylori-Negative Gastritis: Algorithm of Diagnosis and Treatment (Literature Review and Resolution of... by V. T. Ivashkin, I. V. Maev, T. L. Lapina, Yu. A. Kucheryavyy, S. R. Abdulkhakov, O. P. Alekseeva, S. A. Alekseenko, D. N. Andreev, I. G. Bakulin, N. V. Bakulina, D. S. Bordin, Z. M. Galeeva, N. N. Dekhnich, N. V. Korochanskaya, R. O. Kuvaev, M. A. Livzan, M. F. Osipenko, S. S. Pirogov, V. I. Simanenkov, O. A. Storonova, A. S. Tertychnyy, A. S. Trukhmanov, Yu. P. Uspenskiy, I. B. Khlynov, V. V. Tsukanov

“…Conventional triple therapy combined with bismuth tripotassium dicitrate allows for achieving optimal cure rates of H. pylori eradication. Addition of rebamipide to regimens of H. pylori eradication improves their efficiency. …”
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BPZ inhibits early mouse embryonic development by disrupting maternal-to-zygotic transition and mitochondrial function by Zhiming Ding, Huilei Chen, Huiru Cheng, Caiyun Wu, Hongzhen Ruan, Bingjing Zhu, Ping Zhou, Zuying Xu, Huifen Xiang

“…Moreover, BPZ exposure is associated with an increase in γ-H2A.X expression. Additionally, BPZ exposure alters the expression levels of histone modifications, including H3K27me2, H3K27me3, H3K9me3, and H3K27ac, in early embryos. …”
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A retrospective analysis on maternal and neonatal outcomes in pSS/AITD pregnancies by Miaoguan Peng, Taizhen Luo, Xiaoshi Weng, Yanmei Dong, Yijuan Xie, Siqi Huang, Naifeng Liang, Shiyun Wen, Yaojie Zhai, Yingjun Xie, Yuyi Chen

“…The average birth weight of newborns in the pSS with AITD group was significantly lower than in the pSS without AITD group (2587.70 ± 720.50 g vs. 2812.54 ± 495.30 g, P < 0.001). Additionally, the rate of low-birth-weight infants in the pSS with AITD group was higher than in the pSS without AITD group (39.0% vs. 19.7%, P = 0.032). …”
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Cobalt (II) phthalocyanine derived Co3O4@HCNFs as highly effective bifunctional electrocatalysts for iodide redox couple reduction (IRR) and oxygen reduction reaction (ORR) by Ziyu Guo, Wenyu Gong, Jianing Guo, Mingxing Wu

“…The remarkable catalytic activity of Co3O4@HCNFs can be ascribed the introduced Co3O4, resulting in additional active sites of Co-N-C, and the synergistic effects between metals and carbon also accounts for the enhanced catalytic activity. …”
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Kaempferol protects against high-salt-induced hypertension and vascular endothelial injury by inhibiting ferroptosis through the ATF4/ACSL4 pathway by Qiuer Liang, Minghao Chen, Guangtian Chen, Pengli Xu, Lai Kwan Lam, Pengcheng Xie, Ting Xie, Wanqing Tu, Tianhao Liu, Xiaopeng Peng, Haoyao Yuan, Liguo Chen, Ya Xiao

“…Using an 8 % high-salt diet model, we evaluated the effects of Kae (200 mg/kg/day) in wild-type (WT) and activating transcription factor 4 (ATF4+/−) knockout mice. Additionally, human aortic endothelial cells (HAECs) cultured under high-salt conditions were used to assess Kae's protective effects, with ATF4 and acyl-CoA synthetase long-chain family member 4 (ACSL4) knocked down via siRNA transfection. …”
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Evaluation of the relatedness between the biofilm-associated genes and antimicrobial resistance among Acinetobacter baumannii isolates in the southwest Iran by Nafiseh Hosseinzadeh Shakib, Zahra Hashemizadeh, Abolfazl Rafati Zomorodi, Reza Khashei, Yeganeh Sadeghi, Abdollah Bazargani

“…Antimicrobial susceptibility testing (AST) was performed using the Kirby-Bauer disk diffusion method, and biofilm production potential was assessed through the tissue culture plate (TCP) method. Additionally, we investigated eleven biofilm-related genes (ompA, bap, csuE, epsA, blaper-1, bfmS, pgaB, csgA, fimH, ptk, and kpsMII) in all isolates using polymerase chain reaction (PCR). …”
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Biofilm Formation by Staphylococcus aureus Isolated from Food Contact Surfaces in the Dairy Industry of Jalisco, Mexico by María-Guadalupe Avila-Novoa, Maricarmen Iñíguez-Moreno, Oscar-Alberto Solís-Velázquez, Jean-Pierre González-Gómez, Pedro-Javier Guerrero-Medina, Melesio Gutiérrez-Lomelí

“…The biofilm production of the S. aureus strains SA-4E, SA-9, SA-13, and SA-19 on stainless-steel coupons was investigated at 25°C for 8 days, and the detected cell population density was approximately 7.15–7.82 log CFU cm−2. In addition to the ability of biofilm production, it is important to highlight that these strains are potential enterotoxin producers as se genes have been previously detected in their genomes. …”
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Deciphering the role of miRNA-mRNA interactions in cerebral vasospasm post intracranial hemorrhage by Xiang Chu, Xiang Chu, Xiyan Zhu, Honghao Xu, Wenbing Zhao, Debin Guo, Xing Chen, Jinze Wu, Lei Li, Hao Wang, Jun Fei

“…By employing the degree scores method for each gene, we identified the top 10 genes and developed a protein-protein interaction (PPI) network. Additionally, we discovered 19 DEMs associated with CVS and integrated them with mRNA dataset analysis to construct a miRNA-mRNA network, which comprised 8 functionally differentially expressed DEMs and 6 target mRNAs. …”
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The features of Tat protein of human immunodeficiency virus type 1 (Retroviridae: <i>Lentivirus: Lentivirus humimdef1</i>) non-A6 variants, characteristic for the Russian Federatio... by Anna I. Kuznetsova, Anastasiia A. Antonova, Aleksey V. Lebedev, Ekaterina N. Ozhmegova, Anastasia V. Shlykova, Ilya A. Lapovok, Oxana V. Galzitskaya

“…Tat protein is a trans-activator of HIV-1 genome transcription, with additional functions including the ability to induce the chronic inflammatory process. …”
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Challenges with achieving and maintaining oral cholera vaccine coverage: insights from serial cross-sectional representative surveys in a cholera-endemic community in the Democrati... by Oliver Cumming, Andrew S Azman, Espoir Bwenge Malembaka, Jackie Knee, Placide Okitayemba Welo, Aimé Cikomola, Aybüke Koyuncu, Patrick Musole Bugeme, Juan Dent, Chloe Hutchins, Hanmeng Xu, Karin Gallandat, Joseph Matundanya, Delphin Rukakiza, Merveille Nkombo, Jaime Saidi Mufitini, Baron Bashige Rumedeka, Laurent Akilimali, Elizabeth C Lee

“…Vaccine refusal was associated with a lack of confidence in the vaccine’s safety, and 29% of unvaccinated adults reported it was unlikely they would accept kOCVs if an additional mass vaccination campaign was conducted in their area. …”
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Optomechanical Gyroscope Based on Micro-Hemispherical Shell and Optical Ring Resonators by Jamal N. A. Hassan, Wenyi Huang, Maoyuan Wang, Senyu Zhang, Guangjun Wen, Yongjun Huang

“…However, effective on-chip light coupling within a confined micro&#x002F;nano system under vacuum posed challenges for conventional angular velocity measurements in prior optomechanical gyroscopes. Additionally, A core challenge in resonant gyroscopes is directly measuring resonant frequency displacement, necessitating alternative angular velocity detection techniques. …”
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Optimizing Flammulina velutipes residue use: impact on health metrics and performance in three-yellow chickens by Yuanxiao Li, Yuanxiao Li, Dan Liu, Wang Li, Wang Li, Longmei Zhao, Pinghua Cao, Yanbo Ma, Yanbo Ma, Ke Ding, Cai Zhang, Cai Zhang, Ning Liu

“…Caecum contents were collected on day 48 to assess flora diversity.Results and discussionNo significant differences were observed in dry matter intake (DMI), average daily gain (ADG), or feed conversion ratio (FCR) between the 2% and 4% group and the CON. …”
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Discovery of the microbiota-gut-brain axis mechanisms of acupuncture for amnestic mild cognitive impairment based on multi-omics analyses: A pilot study by Zi-Han Yin, Qiong-Nan Bao, Ya-Qin Li, Yi-Wei Liu, Zi-Qi Wang, Fang Ye, Xia He, Xin-Yue Zhang, Wan-Qi Zhong, Ke-Xin Wu, Jin Yao, Zi-Wen Chen, Ling Zhao, Fan-Rong Liang

“…The primary outcome was the change in the Alzheimer’s Disease Assessment Scale-Cognitive Scale (ADAS-Cog) score. In addition, multi-omics was performed to detect changes in brain function, gut microbiota, and serum metabolites. …”
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Use of a wearable device to improve sleep quality by Susan L. Moore, Susan L. Moore, Evan P. Carey, Kristyna Finikiotis, Kelsey L. Ford, Richard D. Zane, Richard D. Zane, Katherine K. Green

“…Exploratory analysis through descriptive statistics was conducted for an additional 36 secondary outcomes.ResultsUse of the digital wellness device was associated with reduced SOL both objectively and subjectively. …”
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Targeting of the HER2/HER3 signaling axis overcomes ligand‐mediated resistance to trastuzumab in HER2‐positive breast cancer by Satomi Watanabe, Kimio Yonesaka, Junko Tanizaki, Yoshikane Nonagase, Naoki Takegawa, Koji Haratani, Hisato Kawakami, Hidetoshi Hayashi, Masayuki Takeda, Junji Tsurutani, Kazuhiko Nakagawa

“…Finally, in heregulin‐expressing BT474‐HRG and JIMT‐1 xenograft models, the addition of pertuzumab and patritumab to trastuzumab also enhanced antitumor efficacy leading to tumor regression. …”
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Bayesian reinforcement learning models reveal how great-tailed grackles improve their behavioral flexibility in serial reversal learning experiments by Lukas, Dieter, McCune, Kelsey, Blaisdell, Aaron, Johnson-Ulrich, Zoe, MacPherson, Maggie, Seitz, Benjamin, Sevchik, August, Logan, Corina

“…Here, we apply and expand newly developed Bayesian reinforcement learning models to gain additional insights into how individuals might dynamically modulate their behavioral flexibility if they experience serial reversals. …”
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3-methyl-4-nitrophenol disturbs the maternal-to-zygotic transition of early embryos by damaging mitochondrial function and histone modification by Fan Chen, An-Feng Luo, Kai-Xin Pan, Hao Gu, Chang-Fan Zhou, Wei Zeng, Song Liu, Adrian Molenaar, Hong-Yan Ren, Li-Jun Huo, Yan-Zhen Bi

“…Moreover, the study demonstrated that these gene expression changes were closely associated with mitochondrial dysfunction, evidenced by diminished mitochondrial membrane potential, reduced ATP production, aberrant expression of mitochondria-related genes, increased ROS accumulation, and heightened DNA damage in PNMC-treated embryos. Additionally, PNMC exposure induced defects in histone modification, as shown by altered levels of H3K9me3 and H3K27me3, H3K9ac and H3K27ac. …”
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The effect of electroslag remelting on the cleanliness of CrNiMoWMnV ultrahigh-strength steels by Ali M., Porter D., Kömi J., Heikkinen E.P., Eissa M., El Faramawy H., Mattar T.

“…Al2O3 inclusions were formed as a result of the addition of Al as a deoxidant to the ESR slag to prevent penetration of oxygen to the molten steel.…”
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