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52161
Downregulation of Long Noncoding RNA LINC00261 Attenuates Myocardial Infarction through the miR-522-3p/Trinucleotide Repeat-Containing Gene 6a (TNRC6A) Axis
Published 2021-01-01“…LINC00261 targets miR-522-3p in cardiomyocytes. In addition, miR-522-3p targets TNRC6A in cardiomyocytes. …”
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52162
Genomic scans for selection and runs of homozygosity in southern Italian turkey populations
Published 2025-02-01“…We identified 27 genomic regions that harbor 61 candidate genes in ROH islands in which single nucleotide polymorphisms (SNPs) occur in more than 90 % of individuals. In addition, we detected 608 genomic regions under positive selection using the iHS method being 104, 98, 130, 102, and 174 for BAS, APU_C, APU_M, APU_PN, and APU_PS, respectively. …”
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52163
Rare Taxa Are Key Links in Regional Antimicrobial Resistance Profiles in Dusts Across Diverse North American Regions
Published 2024-11-01“…ABSTRACT The role of bioaerosols in the dispersal of antimicrobial resistance genes (ARGs) and resistant microorganisms is poorly understood. In addition, bioaerosols are powerful composite samples representative of the surrounding environment and can be used as sentinels of many local habitats. …”
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52164
Allelopathic effects on vegetative propagation, physiological-biochemical characteristic of Alternanthera philoxeroides (Mart.) Griseb from Cinnamomum camphora (L.) Presl.
Published 2025-01-01“…The findings revealed that the leaves of C. camphora exhibited the capability to suppress the asexual reproduction of A. philoxeroides. The addition of C. camphora leaves resulted in inhibition of the fresh weight, stem length, and stem node number of A. philoxeroides new stems, with the strength of inhibition increasing in proportion to the quantity of C. camphora leaves added. …”
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52165
Preventing Severe COVID-19 with Tixagevimab-Cilgavimab in Hematological Patients Treated with Anti-CD20 Monoclonal Antibodies: An International Multicenter Study
Published 2024-12-01“…The study included 749 patients with HM treated with anti-CD20 between February 15 and June 30, 2022, comparing 215 who received T-C prophylaxis to 534 who did not. Results The study revealed a significant reduction in the risk of COVID-19 among patients who received T-C prophylaxis compared to those who did not (11.2% vs 23.4%, p < 0.001), with hazard ratio (HR) of 0.40 (95% CI 0.26–0.63), adjusted for age, sex, vaccination status, baseline HM malignancy and type of anti-CD-20. …”
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52166
Effect of Acetyl tributyl citrate on bone metabolism based on network toxicology and molecular docking technology
Published 2025-01-01“…Following rigorous refinement using the STRING platform and Cytoscape software, we pinpointed ten core targets, encompassing KDM1A, EP300, HDAC2, EHMT2, DNMT1, and several others. …”
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52167
Hemodynamic and Lesion Characteristics Associated with Discordance between the Instantaneous Wave-Free Ratio and Fractional Flow Reserve
Published 2019-01-01“…Even if iFR is functionally significant in intermediate stenosis, additional FFR evaluations should be considered for women, especially those with a high rate-pressure product, to avoid unnecessary percutaneous coronary intervention. …”
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52168
Does engaging in ESG practices improve banks’ performance in Jordan?
Published 2025-02-01“…Similarly, as the bank ages by one year, its performance improves, with the ROA and Tobin’s Q models showing increases of 0.216 and 0.116 units, respectively. Additionally, the financial development showed correlation coefficients of 0.108 and 0.045 for the ROA and Tobin’s Q models, respectively. …”
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52169
Trends in incidence, mortality, and DALYs of cystic echinococcosis in Central Asia from 1992 to 2021: an age-period-cohort analysis
Published 2025-01-01“…The joinpoint regression model was employed to calculate the annual percentage change (APC) and average APC (AAPC) to identify shifts in disease trends. Additionally, an age-period-cohort model was used to assess the impact of various age groups, periods, and birth cohorts on the disease burden.ResultsThe number of CE cases increased by 52.13% in Central Asia, while deaths decreased by 57.35%; DALYs decreased only slightly by 10.75%. …”
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52170
Transcription Factor E2F-1 Is Upregulated in Human Gastric Cancer Tissues and Its Overexpression Suppresses Gastric Tumor Cell Proliferation
Published 2007-01-01“…PCR-SSCP analysis demonstrated that mutations were not detected in any of the gastric cancer and normal tissue specimens. In addition, the results of an immunohistochemistry assay revealed higher expression rates of E2F-1 (P < 0.01) in gastric cancer tissues (72.5%) than in paratumor tissues (30.0%) of the same individuals and stomach mucosa from healthy individuals (22.5%). …”
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52171
Control of peritectic phase content and its effect on properties of CuSn20P1 alloy by semi-solid rheological forming
Published 2025-01-01“…Interestingly, the δ-phase content decreased significantly with the increase in mold temperature. In addition, the β are tightly bound to the α-Cu and exist semi-coherent interface matching in (101) β//(-1-10) α-Cu. …”
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52172
Perioperative SARS-CoV-2 Infection in Patients Undergoing Elective Surgery in Gynecology Clinic: Tertiary Center Experience
Published 2022-08-01“…Postoperative respiratory and other system complications did not occur in nine patients, previously diagnosed with COVID-19. …”
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52173
Compost quality optimization through Plackett-Burman’s design
Published 2024-10-01“…Leachate recirculation showed significant effect on compost humidity increase, which decreased its physical quality to not permitted values by Peruvian technical standards. In addition, leachate uses a reduced number of corn leaves, as well as its fresh and dry weight. …”
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52174
Novel N-quaternary coumarin-3-yl-imidazo[1,2-a]pyridines as fluorescent hybrids: Their synthesis and biological evaluation in cancer cells
Published 2025-01-01“…Furthermore, these same structures demonstrated substantial fluorescence emissions localized within the cytoplasm. Additionally, compounds decreased the G2/M phase of the cell cycle and increased the SubG1 phase. …”
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52175
Cervical cancer screening: Impact of collection technique on human papillomavirus detection and genotyping
Published 2025-02-01“…Our study defines the kappa agreement between self- and speculum-based collection techniques for 15 types of high-risk HPV. Additionally, we describe the sensitivity and specificity ratios for HPV testing using both collection methods. …”
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52176
Identification of key chromium resistance genes in Cellulomonas using transcriptomics
Published 2025-02-01“…Cytochrome c subunits encoding genes qcrA and qcrC were involved in the intracellular reduction of Cr(VI), and cytochrome c oxidase subunits encoding genes coxB and coxC were involved in extracellular electron secretion. Additionally, several unreported genes were found to be upregulated in C. fimi Clb-11 under Cr(VI) stress. …”
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52177
Mechanism of Threshold Voltage Instability in Double Gate α-IGZO Nanosheet TFT Under Bias and Temperature Stress
Published 2024-01-01“…The reported DG-IGZO-NSTFTs exhibit a negative side threshold voltage shift (<inline-formula> <tex-math notation="LaTeX">$\Delta$ </tex-math></inline-formula>Vth) accompanied by an increase in Ion/Ion(0) under negative bias temperature stress (NBTS) at elevated temperatures, which indicates the presence of additional charges. An anomalous negative side shifting of the Vth is observed under positive bias temperature stress (PBTS), where diffused hydrogen atoms are identified as introducing excess n-type carriers into the channel and causing the observed <inline-formula> <tex-math notation="LaTeX">$\Delta$ </tex-math></inline-formula>Vth. …”
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52178
Clinical Significance of Perioperative Minimal Residual Disease Detected by Circulating Tumor DNA in Patients With Lung Cancer With a Long Follow-up Data: An Exploratory Study
Published 2025-03-01“…Introduction: Molecular residual disease detected by circulating tumor DNA (ctDNA) has been reported to be predictive of patients’ outcomes in various types of cancers after curative intent treatment. Nevertheless, additional detailed information regarding the association of longitudinal ctDNA detection with long-term follow-up in lung cancer is needed. …”
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52179
Economic feasibility assessment and parameter sensitivity analysis of rainwater harvesting systems in different climatic zones of China
Published 2025-12-01“…The Particle Swarm Optimization (PSO) was employed to optimize the cistern volume by integrating Net Present Value (NPV) and Benefit Cost Ratio (BCR). Additionally, multiple nonlinear regression analyses were employed to quantify the relationship between various catchment subsurfaces and the optimal reservoir volume. …”
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52180
Unveiling Silent Atherosclerosis in Type 1 Diabetes: The Role of Glycoprotein and Lipoprotein Lipidomics, and Cardiac Autonomic Neuropathy
Published 2025-01-01“…<b>Introduction:</b> This study aimed to evaluate whether glycoprotein and lipoprotein lipidomics profiles could enhance a clinical predictive model for carotid subclinical atherosclerosis in patients with type 1 diabetes (T1D). Additionally, we assessed the influence of cardiac autonomic neuropathy (CAN) on these predictive models. …”
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