Propionate metabolism in a human pathogenic fungus: proteomic and biochemical analyses by Luiz Paulo Araújo Santos, Leandro do Prado Assunção, Patrícia de Souza Lima, Gabriel Brum Tristão, Matthias Brock, Clayton Luiz Borges, Mirelle Garcia Silva-Bailão, Célia Maria de Almeida Soares, Alexandre Melo Bailão

“…Propionyl-CoA is a toxic compound formed during the degradation of odd-chain fatty acids, branched chain amino acids and cholesterol. …”
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Ice speed of a Greenlandic tidewater glacier modulated by tide, melt, and rain by S. Sugiyama, S. Sugiyama, S. Tsutaki, S. Tsutaki, D. Sakakibara, D. Sakakibara, I. Asaji, K. Kondo, Y. Wang, E. Podolskiy, G. Jouvet, G. Jouvet, M. Funk

“…During the melt season, ice speed is controlled by atmospheric conditions through meltwater production and rain events, as is commonly observed in alpine glaciers, but additional complexity arises from tidal influence near the calving front.…”
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Adaptive anomaly detection disruption prediction starting from first discharge on tokamak by X.K. Ai, W. Zheng, M. Zhang, Y.H. Ding, D.L. Chen, Z.Y. Chen, B.H. Guo, C.S. Shen, N.C. Wang, Z.J. Yang, Z.P. Chen, Y. Pan, B. Shen, B.J. Xiao, J-TEXT team

“…By training the E-CAAD model on data from existing devices, the predictor can effectively distinguish between disruption precursor and non-disruption samples in new device, enabling disruption prediction from the first shot on the new device. Additionally, adaptive learning from scratch and alarm threshold adaptive adjustment strategies are proposed to enable model automatically adapt to changes in the discharge scenario. …”
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Impact of Collagenated and Non-Collagenated Deproteinized Bovine Bone Mineral on Schneiderian Membrane Integrity in Rabbits by Rihito Yamada, Samuel Porfirio Xavier, Yasushi Nakajima, Erick Ricardo Silva, Daniele Botticelli, Yuki Teranishi, Shunsuke Baba

“…<b>Conclusions</b>: The addition of 10% collagen to deproteinized bovine bone mineral initially provided protection against mucosal thinning and perforation after 2 weeks of healing. …”
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Sustainability index analysis of organic fertilizer production from paunch manure and rice straw waste by A.D. Santoso, F.D. Arianti, E.S. Rohaeni, B. Haryanto, M.D. Pertiwi, L.P. Panggabean, A. Prabowo, S. Sundari, S.P. Wijayanti, I.N. Djarot, F.D. Kurniawati, F.L. Sahwan, T. Prasetyo, A. Barkah, T.A. Adibroto, R. Ridlo, I. Febijanto, A.A. Wasil, S. Lusiana, R. Rosmeika, R.B. Heryanto

“…As a result, the o use of agricultural waste as a valuable addition to a perfect social, economical, and technological development system needs to be encouraged. …”
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Preoperative carcinoembryonic antigen to lymphocyte ratio serves as a prognostic predictor in elderly patients with colorectal cancer: a multicentre retrospective study by Lei Jiang, Ning Tan, Xiaonan Zhang, Jiayi Jiang, Xinyi Li, Gang Deng, Tao Liang, Haohan Ma, Weiping Deng, Lichang Guan, Kaijun Zhang, Xujie Cai, Lishu Xu

“…The carcinoembryonic antigen (CEA) to lymphocyte ratio (CLR) was derived from the derivation cohort and subsequently validated in two additional cohorts. The observed end point was all-cause death during the follow-up period postoperation.Results In the derivation cohort, CLR demonstrated an independent association with all-cause mortality. …”
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Heat Re-process approach and thermally integrated renewable energy system for power, compressed hydrogen, and freshwater production; ANN boosted optimization and techno-enviro-econ... by Zhaoyang Zuo, Junhua Wang, Mohammed A. Alghassab, Nashwan Adnan Othman, Ahmad Almadhor, Fahad M. Alhomayani, Hind Albalawi, Samah G. Babiker, Barno Abdullaeva, Aboulbaba Eladeb

“…A key innovation is using waste heat from the SCO2-BC to power an organic Rankine cycle (ORC), which improves the performance and power generation capacity of the proposed system. Additionally, the machine learning optimization technique is employed to optimize the system, significantly reducing computational costs and runtime for the optimization process. …”
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Endogenous 17β-estradiol regulates sexually dimorphic anxiety responses in zebrafish via the HPI axis and 5-HT/DA pathways by Hong Tao, Hong Tao, Ying–Ying Zhang, Ying–Ying Zhang, Yan–Jun Shen, Yan–Jun Shen, Qi–Liang Chen, Qi–Liang Chen, Zhi–Hao Liu, Zhi–Hao Liu

“…Treatment with LET significantly decreased E2 levels in the plasma and brain of female zebrafish, which corresponded with reduced anxiety responses, lower plasma cortisol levels, and increased brain 5-HT and DA content. Additionally, the expression of genes associated with E2, cortisol, 5- HT, and DA pathways was relevantly altered. …”
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Serum IL-18 Is a Potential Biomarker for Predicting Severe Dengue Disease Progression by Josephine Diony Nanda, Chiau-Jing Jung, Rahmat Dani Satria, Ming-Kai Jhan, Ting-Jing Shen, Po-Chun Tseng, Yung-Ting Wang, Tzong-Shiann Ho, Chiou-Feng Lin

“…In addition, decreased platelets were significantly (P<0.05) associated with increased IL-18. …”
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Expression Analysis of Fibronectin Type III Domain-Containing (FNDC) Genes in Inflammatory Bowel Disease and Colorectal Cancer by Tilo Wuensch, Jonas Wizenty, Janina Quint, Wolfgang Spitz, Madeleen Bosma, Olaf Becker, Andreas Adler, Wilfried Veltzke-Schlieker, Martin Stockmann, Sascha Weiss, Matthias Biebl, Johann Pratschke, Felix Aigner

“…Gene expression was determined by quantitative real-time PCR. In addition, FNDC expression data from publicly available Gene Expression Omnibus (GEO) data sets (GDS4296, GDS4515, and GDS5232) were analyzed. …”
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Standardization and validation of a novel reverse transcriptase polymerase chain reaction method for detecting virulent strains of the infectious bursal disease virus by Vladimir Longa-Bobadilla, Phillip Ormeño-Vásquez, Manuel Criollo-Orozco, Luis Tataje-Lavanda, Katherine Huamán-Gutierrez, Ángela Montalván, Mirko Zimic, Manolo Fernández-Sanchez, Manolo Fernández-Díaz

“…Results: After determining the optimal RT-PCR conditions, the newly designed primers successfully amplified a 402-bp consensus sequence of the VP5 gene. In addition, these primers specifically amplified the VP5 sequence of the IBDV-positive samples, not the other samples previously confirmed to be positive for other common poultry pathogens. …”
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Exploring the Effects of <i>Gracilaria lemaneiformis</i> Polysaccharides on the Fecal Microbiota and Fecal Metabolites of Fattening Pigs Based on 16S rDNA and Metabolome Sequencing by Mingyang Jia, Qiang Ma, Hongjun Wang, Xiangzhou Yan, Lei Wang, Baosong Xing, Qingxia Lu, Jing Wang

“…These results indicate that dietary GLP supplementation can improve the antioxidant ability, anti-inflammatory ability, and immune level of fattening pigs by regulating fecal flora and metabolites and could be used as a functional feed additive.…”
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Associations between exposure to volatile organic compounds with obesity in adults by Runmiao Wu, Lei Jia, Xu Zhu, Gongchang Guan, Junkui Wang, Rutai Hui, Meijuan Ma, Zhao Zhao, Hui Pang, Ling Zhu

“…Linear regression and logistic regression models were employed to estimate β-coefficients or odds ratios (ORs) along with their corresponding 95 % confidence intervals (CIs). …”
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Identification and functional analysis of hub genes involved in deoxynivalenol-induced enterotoxicity in porcine (Sus scrofa) by Jinhua He, Geng Zhao, Mingxia Chen, Ximing Ren, Peizhi Zhu, Zhizhong Liu, Jiayi Zhou, Hanwei Chen, Chuqiao Xiao, Xiang-Guang Li

“…Further analysis revealed that the up-regulated DEGs were enriched in tumor necrosis factor, nuclear factor kappa-B, mitogen-activated protein kinases, and Janus kinase/signal transducer and activator of transcription-related signaling pathways. In addition, Weighted gene co-expression network analysis was performed to identify highly co-expressed modules. …”
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Progress in voluntary medical male circumcision for HIV prevention supported by the US President’s Emergency Plan for AIDS Relief through 2017: longitudinal and recent cross-sectio... by Carlos Toledo, Melissa Habel, Stephanie M Davis, Jonas Z Hines, Jonathan M Grund, Renee Ridzon, Brittney Baack, Jonathan Davitte, Anne Thomas, Valerian Kiggundu, Naomi Bock, Paran Pordell, Caroline Cooney, Irum Zaidi

“…The VMMC programme has achieved rapid scale-up but continues to face challenges, and new approaches may be needed to achieve the new Joint United Nations Programme on HIV/AIDS goal of 27 million additional circumcisions through 2020.…”
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Research note: Establishment of a multiplex PCR detection system for different infectious bronchitis virus strain genotypes in laying hens by Changjing Zhao, Cheng Yuan, Qingsen Zhao, Aihong Xia, Yaqing Dong, Shuying Xu, Shihan Chen, Yue Yuan, Yongjuan Wang

“…This study produced a method for the fast detection and identification of five strains of infectious bronchitis virus (IBV), including the currently prevalent wild-type QX and G Ⅵ-1 strains, in addition to the Mass, 4/91, and LDT3 strains that are used as vaccines. …”
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A novel multimodality anthropomorphic phantom enhances compliance with quality assurance guidelines for magnetic resonance imaging in radiotherapy by Meshal Alzahrani, David A Broadbent, Irvin Teh, Bashar Al-Qaisieh, Emily Johnstone, Richard Speight

“…For comprehensive QA, both ACR and anthropomorphic phantoms are required. Additionally, large field-of-view (FOV) phantoms are crucial for evaluating large FOV MRI distortions.…”
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Improving the integrity and reproducibility of research that uses antibodies: a technical, data sharing, behavioral and policy challenge by M. Biddle, P. Stylianou, M. Rekas, A. Wright, J. Sousa, D. Ruddy, M. I. Stefana, K. Kmiecik, A. Bandrowski, R.A. Kahn, C. Laflamme, E. M. Krockow, H.S. Virk

“…Yet many antibodies used in research do not recognize their intended target, or recognize additional molecules, compromising the integrity of research findings and leading to waste of resources, lack of reproducibility, failure of research projects, and delays in drug development. …”
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Revealing the core suppression effects of various Di (2-ethylhexyl) phthalate exposure on early meiosis progression in postnatal male mice via single-cell RNA sequencing by Baoquan Han, Lei Hua, Shuai Yu, Wei Ge, Cong Huang, Yu Tian, Chunxiao Li, Jiamao Yan, Tian Qiao, Jiachen Guo, Dongliang Lu, Bin Wang, Diya Cai, Yunqi Zhang, Shaolin Liang, Jianjuan Zhao, Qi Hou, Wei Shen, Zhongyi Sun

Subjects: “…Di (2-ethylhexyl) phthalate…”
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Axonal regeneration and innervation ratio following supercharged end-to-side nerve transfer by Leopold Harnoncourt, Martin Schmoll, Christopher Festin, Laurenz Pflaum, Markus Breuss, Johanna Klepetko, Dominik C. Dotzauer, Florian J. Jaklin, Udo Maierhofer, Philipp Tratnig-Frankl, Oskar C. Aszmann, Oskar C. Aszmann

“…In these cases, supercharged end-to-side (SETS) nerve transfers preserve the continuity of the original nerves while facilitating additional axonal support to mitigate muscle atrophy. …”
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