Inverse relationship of oxidative balance score with hyperuricemia among Chinese adults: a population-based cross-sectional study by Hewei Peng, Ying Han, Jingru Huang, Wenxin Qiu, Huajing Chang, Jiangwang Fang, Xian-E Peng

“…An inverse association between OBS and hyperuricemia was observed and remained after adjusting for potential confounders. Each additional unit of OBS was associated with a 4% and 7% reduction in the risk of hyperuricemia in men [OR: 0.96(0.94,0.99)] and women [OR: 0.93(0.90,0.96)], respectively. …”
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Effects of chronic diseases on health related quality of life is mediated by sleep difficulty in middle aged and older adults by Yaoyao Wu, Zesheng Chen, Zongxue Cheng, Zhecong Yu, Kang Qin, Caixia Jiang, Jue Xu

“…After correcting for demographic and life characteristics, the mediation analysis results indicated that sleep difficulty mediated the relationship between chronic diseases and HRQoL (β=-0.0022, 95% Bca CI: -0.0034 -0.0014). Additionally, sleep difficulty influenced the association between chronic diseases and daily activities as well as pain (or discomfort) (β = 0.0083, 95% Bca CI: 0.0042–0.0111; β = 0.0162, 95% Bca CI: 0.0107–0.0225) in the analysis of the dimensions. …”
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HfC–HfO2 modified high/superhigh temperature thermal protection coating for superior hot corrosion resistance and antioxidation performance by Zhiyun Ye, Shuqi Wang, Shuang Yu, Xinrui Zhao, Yongchun Zou, Guoliang Chen, Lei Wen, Lina Zhao, Guangxi Zhang, Yaming Wang, Jiahu Ouyang, Dechang Jia, Yu Zhou

“…This improvement is attributed to the formation of a robust Hf-rich skeleton provided by the deposited HfC–HfO2 layer, which can accelerate the formation of a highly stable corroded layer/oxide scale. In addition, multiple stress release mechanisms of the composite coating at high temperatures also provide substantial contributions to long-term service. …”
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Neoandrographolide inhibits mature osteoclast differentiation to alleviate bone loss and treat osteoporosis by Kai Tang, Kai Tang, Kai Tang, Wei Deng, Wei Deng, Wei Deng, Wei Deng, Zhiying Huang, Zhiying Huang, Zhiying Huang, Simin Chen, Simin Chen, Simin Chen, Zilin Zhu, Zilin Zhu, Shukun Lin, Shukun Lin, Lubin Zhong, Lubin Zhong, Quanxin Zheng, Quanxin Zheng, Wenhua Zhao, Wenhua Zhao, Zhida Zhang, Zhida Zhang, Ling Mo, Ling Mo, Ling Mo

“…Western blot findings also indicate that NEO inhibits the phosphorylation of ERK, P38, JNK, and P65 but does not reverse the degradation of IκB-α. Additionally, NEO affects the phosphorylation of proteins in the PI3K/AKT, GSK3β, and PPARγ signaling pathways, demonstrating that NEO can inhibit OC formation through multiple pathways and targets. …”
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Clinical features of cystic neutrophil granulomatous mastitis in 62 cases by Mengjie Wang, Dongxiao Zhang, Na Fu, Min Liu, Hongkai Zhang, Shuo Feng, Yifei Zeng, Wenjie Zhao, Jianchun Cui, Khattak Mazher Mansoor

“…The primary clinical manifestations were characterized by pain and palpable masses, accompanied by redness, ulceration, nipple discharge, and nipple retraction. Additionally, systemic symptoms, such as fever, headache, erythema nodosum, and cough, were observed. …”
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Computerized QT and QTc Measurements From Bedside ICU Monitors Are Similar to Those Derived From a Standard 12‐Lead ECG by Arthur Murray, Karolina Ho, Thomas J. Hoffmann, Gopika K. Ganesh, Shelvin Prasad, Sarah Berger, Cass Sandoval, Amy Larsen, Hildy Schell‐Chaple, Michele M. Pelter

“…These pilot data are promising and suggest QT/QTc measurements from bedside monitors (four leads) may be an acceptable alternative to obtaining additional standard 12‐lead ECGs. Given that half of the ICU patients screened did not have a 12‐lead ECG recorded, bedside monitor QT/QTc's could identify at‐risk patients. …”
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Experimental study of thaw settlement and internal structural changes in frozen soil during the thawing process by Chunguang Xu, Ze Zhang, Yaojun Zhao, Doudou Jin, Qihao Yu, Xiangxi Meng

“…The results indicated that there were variations in the packing density of the soil–ice mixtures according to the soil type. Additionally, the packing density exhibited a favourable correlation with the water content, and the following size relationship for the packing density of the different soil types at the same water content could be established: ST (sand) > HB (silty loam) > SL (sandy loam) > YC (silty clay). …”
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Antimicrobial Residues in Poultry Litter: Assessing the Association of Antimicrobial Persistence with Resistant <i>Escherichia coli</i> Strains by Paula Cortés, Ekaterina Pokrant, Karina Yévenes, Aldo Maddaleno, Andrés Flores, María Belén Vargas, Lina Trincado, Matías Maturana, Lisette Lapierre, Javiera Cornejo

“…<b>Methods</b>: Forty broiler chickens were raised under controlled conditions and divided into three experimental groups, each treated with a different antimicrobial, in addition to an untreated/control group. Litter samples were collected post treatment, analyzed by UPLC-MS/MS, and processed for the isolation of <i>E. coli</i>. …”
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Therapeutic benefit of the dual ALK/FAK inhibitor ESK440 in ALK-driven neuroblastoma by Seema Chugh, Jean C. Tien, Jennifer Hon, Carson Kenum, Rahul Mannan, Yunhui Cheng, Chi Chiang Li, Zainab I. Taher, Andrew D. Delekta, Pushpinder Singh Bawa, Ingrid J. Apel, Stephanie J. Miner, Xuhong Cao, Rohit Mehra, Saravana M. Dhanasekaran, Yuanyuan Qiao, Rajen Mody, Arul M. Chinnaiyan

“…Genomic studies have identified common driver aberrations in high-risk NB, such as MYCN amplification. In addition, a proportion of high-risk patients harbor amplification or activating mutations in anaplastic lymphoma kinase (ALK), and co-occurrence of ALK mutations and MYCN amplification have been associated with aggressive disease. …”
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Effects of Standardized Natural Citrus Extract on Growth, Gut Health, Carcass Quality, and Welfare of Broiler Chickens by Sekhou Cisse, Arkadiusz Matuszewski, Damian Bień, Patrycja Ciborowska, Anna Zalewska, Jakub Urban, Monika Michalczuk, Marta Mendel, Urszula Latek, Joanna Polak, Małgorzata Sobczak-Filipiak, Paweł Konieczka, Mohammed El Amine Benarbia

“…The carcass weight was also significantly higher in the SNCE group. In addition, the fat percentage was lower in the SNCE group. …”
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Beneficial Effect of Multidomain Cognitive Training on the Neuropsychological Performance of Patients with Early-Stage Alzheimer’s Disease by Anastasia Nousia, Vasileios Siokas, Eleni Aretouli, Lambros Messinis, Athina-Maria Aloizou, Maria Martzoukou, Maria Karala, Charalampos Koumpoulis, Grigorios Nasios, Efthimios Dardiotis

“…Considering the limited efficacy of current pharmacological therapies in AD, concurrent computer-based MCT may represent an additional enhancing treatment option in early-stage AD patients.…”
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Advancements and challenges in agriculture: a comprehensive review of machine learning and IoT applications in vertical farming and controlled environment agriculture by Binoy Sasmal, Gobinda Das, Preeti Mallick, Sneha Dey, Suman Ghorai, Subrata Jana, Chiranjibe Jana

“…According to the research, to feed 8 billion people, we would need an additional 109 hectares of land. That is the typical problem that the farmers will face because most of the hollandaise nowadays. …”
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MR Imaging of Prostate Cancer: Diffusion Weighted Imaging and (3D) Hydrogen 1 (1H) MR Spectroscopy in Comparison with Histology by J. Yamamura, G. Salomon, R. Buchert, A. Hohenstein, J. Graessner, H. Huland, M. Graefen, G. Adam, U. Wedegaetner

“…The results of our study showed that both DWI and MRS should be considered as an additional and complementary tool to the T2-weighted MRI for detecting prostate cancer.…”
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Waste ceramic powder for sustainable concrete production as supplementary cementitious material by Yasin Onuralp Özkılıç, Yasin Onuralp Özkılıç, Alireza Bahrami, Yusuf Güzel, Ali Sinan Soğancı, Memduh Karalar, Essam Althaqafi, Ali İhsan Çelik, Özer Zeybek, P. Jagadesh

“…Furthermore, taking into account our experimental research and previous studies on concrete produced utilizing WCP, straightforward equations were provided for practical use to predict CS, STS, and FS. In addition, scanning electron microscopy was done to validate the findings obtained from the experimental part of the study. …”
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Alleviating heat stress on broiler breeder hens: Effect of dietary antioxidant supplementation on reproductive performance, egg quality, offspring growth, and antioxidant capacity by Phocharapon Pasri, Chayanan Pukkung, Pascal Mermillod, Nadine Gérard, Orapin Jantasaeng, Merisa Sirisopapong, Supattra Okrathok, Thanatat Thiabching, Sitthipong Rakngam, Kanokwan Kamkajon, Yongcai Zhu, Sutisa Khempaka

“…Although the body weight of offspring from either antioxidant source was initially low on day 1, it subsequently increased until reaching levels comparable to those in the TN and HS without supplementation by 3 weeks of age (P > 0.05). …”
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Codon usage patterns and genomic variation analysis of chloroplast genomes provides new insights into the evolution of Aroideae by Xinbi Jia, Jiaqi Wei, Yuewen Chen, Chenghong Zeng, Chan Deng, Pengchen Zeng, Yufei Tang, Qinghong Zhou, Yingjin Huang, Qianglong Zhu

“…Thirteen to twenty optimal codons ending in A/T were identified in 61 Aroideae species. Additionally, the comparative analysis of CPGs revealed that two single copy regions and non-coding regions were variable in Aroideae. …”
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Mineralocorticoid axis activity and cardiac remodeling in patients with ACTH-dependent Cushing’s syndrome by Peter Wolf, Simon Travers, Oliver Domenig, Stephanie Baron, Anne Blanchard, Khaoula Bouazizi, Nadjia Kachenoura, Sylvie Salenave, Marko Poglitsch, Alban Redheuil, Severine Trabado, Jacques Young, Philippe Chanson, Peter Kamenický

“…Changes in the renin–angiotensin system and in the mineralocorticoid axis activity could be involved as potential mechanisms in their pathogenesis, in addition to cortisol excess. Methods: In this ancillary study of our previous study prospectively investigating patients with ACTH-dependent Cushing’s syndrome by cardiac magnetic resonance imaging (NCT02202902), 11 patients without any interfering medication were cross-sectionally compared to 20 control subjects matched for age, sex and body mass index. …”
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Identifying biomarkers for epilepsy after cerebral malaria in Zambian children: rationale and design of a prospective observational study by Bo Zhang, Archana A Patel, Gretchen L Birbeck, Maitreyi Mazumdar, Suzanna Mwanza, Rosemary Nyirongo, Dixon Berejena, Joseph Kasolo, Tina Mwale, Violet Nambeye, Kafula Lisa Nkole, Nfwama Kawatu, Alexander Rotenberg

“…We propose to study the sensitivity of quantitative and qualitative EEG metrics in predicting PME, and the potential increased sensitivity of this measure with additional clinical metrics. Our goal is to develop a predictive PME index composed of EEG and clinical history metrics that are highly feasible to obtain in low-resourced regions.Methods and analyses This prospective observational study being conducted in Eastern Zambia will recruit 250 children aged 6 months to 11 years presenting with acute CM and follow them for two years. …”
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Angiopoietin-2 and D-dimer add prognostic information to clinical risk in pulmonary arterial hypertension by Heather L. Clark, Daniel Lachant, Allison N. Light, Deborah Haight, Samia Lopia, Nigel Mackman, R. James White

“…Conclusions: Angiopoietin-2 and D-dimer are elevated in patients with PAH and may add prognostic information to routine clinical assessment.…”
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Targeting Cutaneous Leishmaniasis with Thiadiazine Thione Derivatives: An In Vivo Study of Its Anti-Inflammatory, Anti-Pyretic, Anti-Nociceptive, and Anti-Sedative Properties by Sarah Sarwar, Nadia Sarwar, Haleema Ali, Rafiullah, Rasool Khan, Ajaz Ahmad, Amin Ullah, Ho Soonmin, Nazif Ullah

“…In the antipyretic assay, C1 and C5 were able to reduce body temperature to a normal level within 1 h of treatment. …”
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