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51921
Care coordination across healthcare systems: development of a research agenda, implications for practice, and recommendations for policy based on a modified Delphi panel
Published 2023-05-01“…We introduced common care scenarios and differentiated recommendations for a large (main) healthcare organisation and external healthcare professionals that contribute additional care.Participants The panel composition included health service providers, decision makers, patients and care community, and researchers. …”
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51922
Enhanced penetration and biofilm eradication by sophorolipid micelles encapsulating Honokiol: a comprehensive solution for biofilm-associated lung infections
Published 2025-02-01“…HK-SL Ms eradicated 71.73% of biofilms by targeting extracellular polysaccharides, extracellular proteins, and viable cells within the biofilm. Additionally, 1.66 log10CFU/mL units of S. aureus within biofilms were killed. …”
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51923
Vegetation height estimation based on machine learning model driven by multi-source data in Eurasian temperate grassland
Published 2025-01-01“…This study utilized machine learning models such as Random Forest (RF), AdaBoost, BP-Neural Network (BPNN), and Stacking Ensemble, combining them with topographic and meteorological data, MODIS reflectance data, and grassland height measurement data. …”
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51924
Assessment of awareness of keratoconus and its relation to eye rubbing among Saudi Arabia population
Published 2025-02-01“…The group with acceptable awareness of KC was predominantly aged between 18 and 30 years and female, with a percentage of 30.4%.ConclusionThe study revealed that Saudi citizens are not knowledgeable about KC and the risks associated with eye rubbing. Additionally, the study identified several KC risk factors, including but not limited to eye rubbing, allergies, and family history. …”
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51925
Microbial dynamics of acute pancreatitis: integrating culture, sequencing, and bile impact on bacterial populations and gaseous metabolites
Published 2025-02-01“…The therapeutic intervention necessitated Hartmann's procedure, culminating in colostomy creation.AimsEmploying a thorough microbiological analysis we attempted to demonstrate whether the microflora isolated from the peripancreatic fluid exhibited a stronger correlation with the contents of the stoma or with the rectal swab. Additionally, we sought to determine the association between later onset of AP and diverticulitis.MethodsFollowing clinical materials from the patient in the initial phase of AP were collected: rectal swab, colostomy bag contents (in the publication referred to as stoma content/stool) and peripancreatic fluid. …”
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51926
Deciphering the generation of heterogeneity in esophageal squamous cell carcinoma metastasis via single-cell multiomics analysis
Published 2025-02-01“…Results Our study identified enhancer-specific activation within epithelial cells orchestrated by the three-dimensional structure of chromatin that regulates SERPINH1 transcription, and promotes the epithelial-mesenchymal transition (EMT) and metastasis of ESCC. Additionally, chromatin element activation facilitated the expression of TNFSF4 in CD8 + exhausted T cells, thereby activating Tregs. …”
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51927
Investigating the psychology of eating after exercise — a scoping review
Published 2025-01-01“…Individuals may consume additional food to refuel their energy stores after exercise (psychological compensatory eating), or consume unhealthy or energy dense foods to reward themselves after exercise, especially if exercise is experienced negatively (post-exercise licensing), however the population-level prevalence of these behaviours is unknown.…”
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51928
Assessment of ecological environment quality and their drivers in urban agglomeration based on a novel remote sensing ecological index
Published 2025-01-01“…This study utilizes the Google Earth Engine (GEE) platform, integrates MODIS imagery and NPP-VIIRS data to develop a Novel Remote Sensing Ecological Index (NRSEI). …”
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51929
Clinical efficacy of a virtual reality tool for the treatment of obesity: study protocol of a randomised controlled trial
Published 2022-06-01“…Readiness to change, BMI, eating habits and physical activity, psychological well-being, body image satisfaction, quality of life in relation to body image, and weight bias internalisation will be assessed at baseline, post intervention, 1-week and 4-week follow-up. …”
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51930
Analysis of the genome data of Acinetobacter baumannii UOL-KIMZ-24, exhibiting multiple drug resistance through efflux pumpsGenebANK/NCBI.
Published 2025-02-01“…The analysis of antibiotic-resistance genes (AMR) depicted 27 genes. where the genes encoding efflux pumps such as adeABC, adeRS, adeJK, and adeMN were the more prominent. In addition, sequence typing (ST) study showed that UOL-KIMZ-24 strain lies in ST2, six prophage sequences and 73 virulence factors were also identified in the studied UOL-KIMZ-24. …”
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51931
Joint Group and Multi Institutional Position Opinion: Cirrhotic Cardiomyopathy—From Fundamentals to Applied Tactics
Published 2024-12-01“…Autocrine and endocrine proinflammatory cytokines (TNF-alpha, IL-6), as well as systemic endotoxemia stemming from impaired intestinal permeability, contribute to myocardial remodeling and fibrosis, which further compromise the contractility and relaxation of the heart. Additionally, relative adrenal insufficiency is often present in cirrhosis, further potentiating cardiac dysfunction, ultimately leading to the development of CCM. …”
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51932
Dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI) in patients with chronic coronary artery disease (CAD) - current state of knowledge and perspective...
Published 2025-02-01“…Emerging options, such as vorapaxar, present additional potential, but also require further validation. …”
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51933
Seroprevalence, incidence estimates, and environmental risk factors for dengue, chikungunya, and Zika infection amongst children living in informal urban settlements in Indonesia a...
Published 2025-01-01“…Trash and flooding were additionally evaluated as dengue risk factors at the settlement level by univariate linear regression. …”
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51934
Molecular Characterization and Pathogenicity of <i>Colletotrichum</i> on Banana Fruits: Wound Effects on Virulence and Cross-Infection
Published 2024-12-01“…Among the banana cultivars, “prata” fruits were the most susceptible, regardless of wounding. Additionally, <i>Colletotrichum</i> isolates from dwarf bananas were pathogenic to mango, papaya, and apple fruits. …”
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51935
Comparative Metabolic Analysis of Different <i>Indica</i> Rice Varieties Associated with Seed Storability
Published 2025-01-01“…Notably, inhibition of the linolenic acid metabolic pathway could enhance seed storability. Additionally, increased accumulations of organic acids, such as succinic acid, D-malic acid, and methylmalonic acid, in the butanoate and propanoate metabolisms were identified as a beneficial factor for seed storage. …”
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51936
Bidirectional Mendelian Randomization Analysis of the Association Between Mitochondrial Proteins and Neurodegenerative Diseases
Published 2025-01-01“…Specifically, associations were found with Alzheimer's disease (AD) (three proteins), Parkinson's disease (PD) (four proteins), amyotrophic lateral sclerosis (ALS) (six proteins), multiple sclerosis (two proteins), and dementia with Lewy bodies (four proteins). Conversely, analyses indicated significant associations of neurodegenerative diseases with mitochondrial protein gene variants, notably with AD, dementia with Lewy bodies, and multiple sclerosis, affecting multiple mitochondrial protein levels. …”
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51937
The association between the dietary inflammatory index and multiple myeloma: a case–control study
Published 2025-01-01“…Abstract The dietary inflammatory index (DII) is a common grading system for diet inflammatory potential. …”
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51938
High quality genome assembly of the brown hare (Lepus europaeus) with chromosome-level scaffolding
Published 2024-03-01“…The brown hare genome is particularly interesting as this species readily hybridizes with the mountain hare (Lepus timidus L.) at the species contact zone in northern Eurasia, producing fertile offspring and resulting in gene flow between the two species. In addition to providing a useful comparison for population studies, the genome can offer insight into the chromosomal evolution among Glires in general and Lagomorpha in particular. …”
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51939
Biomass burning emission analysis based on MODIS aerosol optical depth and AeroCom multi-model simulations: implications for model constraints and emission inventories
Published 2025-02-01“…More generally, there is the need for additional efforts at constraining aerosol source strength and other model attributes with multi-platform observations.…”
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51940
ERRα promotes glycolytic metabolism and targets the NLRP3/caspase-1/GSDMD pathway to regulate pyroptosis in endometrial cancer
Published 2023-10-01“…The results of these experiments were further confirmed in endometrial cancer (EC)-derived organoids and nude mice. In addition, the expression of ERRα-related pyroptosis genes was analyzed using The Cancer Genome Atlas and Gene Expression Omnibus database. …”
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