Diabetes control in public assistance recipients and free/low-cost medical care program beneficiaries in Japan: a retrospective cross-sectional study by Daisuke Nishioka, Mitsuhiko Funakoshi, Seiji Haruguchi, Sakae Yonemura, Takashi Takebe, Misato Nonaka, Sanae Iwashita

“…Among patients aged ˂65 years with HbA1c levels above 7%, the adjusted OR was significantly higher in FLCMC programme beneficiaries (OR=3.82, 95% CI: 1.65 to 10.43) than in PHI-only beneficiaries. Additionally, the adjusted OR was significantly higher in FLCMC programme beneficiaries aged ˂65 years (OR=2.57, 95% CI: 1.02 to 7.44) than in PARs.Conclusions This study highlights the predictive value of public assistance or the FLCMC programme for poor blood glucose control and suggests the inadequacy of current medical expense subsidies to eliminate health disparities in diabetes control.…”
Get full text

Asymptomatic malaria parasitaemia and seizure control in children with nodding syndrome; a cross-sectional study by Charles R J C Newton, Albert Ningwa, Kevin Marsh, Richard Idro, Rodney Ogwang, Ronald Anguzu, Pamela Akun, Edward Kayongo

“…The number of seizures in asymptomatic persons was 3.0 (IQR 2.0–7.3) and 6.0 (IQR 4.0–10.0) in symptomatic individuals, p=0.024. Additionally, in asymptomatic patients, a positive correlation was observed between the parasite density and number of seizures, r=0.33, p=0.002.Conclusion In patients with nodding syndrome, both asymptomatic and symptomatic malaria are associated with an increased risk of seizures and poorer seizure control. …”
Get full text

Quick sequential organ failure assessment score combined with other sepsis-related risk factors to predict in-hospital mortality: Post-hoc analysis of prospective multicenter study... by Ryo Ueno, Takateru Masubuchi, Atsushi Shiraishi, Satoshi Gando, Toshikazu Abe, Shigeki Kushimoto, Toshihiko Mayumi, Seitaro Fujishima, Akiyoshi Hagiwara, Toru Hifumi, Akira Endo, Takayuki Komatsu, Joji Kotani, Kohji Okamoto, Junichi Sasaki, Yasukazu Shiino, Yutaka Umemura

“…The AUC for predicting in-hospital mortality was 0.627 (95% confidence interval [CI]: 0.580-0.673) for the qSOFA-Only model. Addition of other variables only marginally improved the model's AUC; the model that included all potentially relevant variables yielded an AUC of only 0.730 (95% CI: 0.687-0.774). …”
Get full text

Img2Vocab: Explore Words Tied to Your Life With LLMs and Social Media Images by Kanta Yamaoka, Ko Watanabe, Koichi Kise, Andreas Dengel, Shoya Ishimaru

“…While our system prioritizes user privacy with opt-in data control and secure design, we explore additional ethical considerations. This paves the way for a future where personalized language learning, grounded in real-world experiences and generative AI, benefits learners.…”
Get full text

2′-O-Methylperlatolic Acid Enhances Insulin-Regulated Blood Glucose-Lowering Effect through Insulin Receptor Signaling Pathway by Wang Yinghao, Guan Qiaoli, Liu Guanfu, Wu Xiaoyun, Wang Xuanjun, Sheng Jun

“…In mice with streptozotocin-induced diabetes, 2-O-M significantly prolonged the blood glucose-lowering effect of insulin, significantly reduced the secretion of exogenous insulin, and reduced the blood glucose concentration in vivo. In addition, treatment with 2-O-M alone significantly enhanced the phosphorylation of AKT in muscle tissue, which enhanced glucose uptake in C2C12 myotubes. …”
Get full text

Short- to Medium-Term Weather Forecast Skill of the AI-Based Pangu-Weather Model Using Automatic Weather Stations in China by Siyi Xu, Yize Zhang, Junping Chen, Yunlong Zhang

“…The results indicate that Pangu surpasses traditional NWP systems in temperature forecasting, while its performance in predicting wind direction, wind speed and pressure is comparable to them. Additionally, the forecast skill of Pangu diminishes as the lead time extends, but it tends to surpass traditional NWP systems with longer lead times. …”
Get full text

Pretreatment with AM1241 Enhances the Analgesic Effect of Intrathecally Administrated Mesenchymal Stem Cells by Junran Xie, Jinxuan Ren, Na Liu, Chengwei Wu, Dongju Xiao, Huanyu Luo, Jingxian Du

“…In untreated CCI mice, expression of TGF-β1 was increased, whereas pretreatment with AM1241-treated mesenchymal stem cells regulated the expression of TGF-β1 on 10 days and 19 days after surgery. In addition, i.t. injection of exogenous TGF-β1 slightly alleviated neuropathic pain whilst neutralization of TGF-β1 potently blocked the effect of AM1241-treated mesenchymal stem cells on thermal hyperalgesia and mechanical allodynia of CCI mice. …”
Get full text

Jackknife versus Lithotomy Position for Hemorrhoidectomy Surgery: A Randomized Controlled Trial by Sina Ghasemi, Behzad Imani, Alireza Jafarkhani, Ashkan Karimi, Ali Yamini

“…Conclusions: Performing hemorrhoidectomy surgery with the Jackknife position compared to the Lithotomy position can reduce the amount of bleeding in patients, shorten the duration of surgery, and provide a better field of view and exposure for the surgeon. Additionally, based on the findings, using either position does not significantly impact the level of local discomfort or postoperative pain.…”
Get full text

Comparative genomics of Botryosphaeria dothidea and B. kuwatsukai, causal agents of apple ring rot, reveals both species expansion of pathogenicity-related genes and variations in... by Bo Wang, Xiaofei Liang, Mark L. Gleason, Rong Zhang, Guangyu Sun

“…Both species encode a significant number of pathogenicity-related genes, e.g.carbohydrateactive enzymes (CAZYs), plant cell wall degrading enzymes (PCWDEs), secondary metabolites (SMs) biosynthetic enzymes, cytochrome P450 enzymes (CYPs), and secreted peptidases, in comparison to all additional sequenced fungal species involved in various life-styles. …”
Get full text

Severe subcutaneous infection with Clostridium septicum in a herd of native Icelandic horses by Charlotta Oddsdóttir, Ólöf G. Sigurðardóttir, Vala Friðriksdóttir, Vilhjálmur Svansson, Birkir Þór Bragason, Sigríður Björnsdóttir

“…The clinical signs included pyrexia, depression, swollen limbs, chest and neck, reluctance to move and dyspnoea, leading to the death or euthanasia of five horses. In addition, one horse was found dead with no previously noted clinical signs. …”
Get full text

Research on path planning for coal mine rescue robots by ZHU Hongbo, YIN Hongliang

“…Next, a correction factor is incorporated into the cost function of the Bidirectional A* algorithm to ensure that the forward and backward search paths intersect, preventing them from diverging. Additionally, a dynamic weighting factor is added to the estimated cost function to eliminate irrelevant expanded nodes during pathfinding, thus improving search efficiency. …”
Get full text

Dietary Histidine Supplementation Maintained Amino Acid Homeostasis and Reduced Hepatic Lipid Accumulation of Juvenile Largemouth Bass, Micropterus Salmoides by Hualiang Liang, Gangchun Xu, Pao Xu, Jian Zhu, Songlin Li, Mingchun Ren

“…In addition, increased dietary histidine levels decreased the lipid content of the whole body and the liver by upregulating the mRNA levels of core genes of the PPARα signaling pathways, including PPARα, CPT1, L-FABP, and PGC1α. …”
Get full text

Effect of regular thicknesses on the microstructural and quantitative analysis for a hypo-eutectic ductile iron alloyed with Ni and V by Colin-García E., Sánchez-Alvarado R.G., Cruz-Ramírez A., Suarez-Rosales M.A., Portuguez-Pardo L., Jiménez-Lugos J.C.

“…The low content of vanadium added to the ductile cast iron had a negligible effect on the solidification pattern, which was mainly due to the graphitizing impact of the nickel and silicon addition. The results of the microstructural characteristics are therefore primarily due to the cooling rate, which is determined by the casting thickness. …”
Get full text

FLT3 is associated with dendritic cell infiltration, tertiary lymphoid structure construction, and predict response to checkpoint inhibitors immunotherapy in solid cancers by Yongchang Tang, Hong Wang, Jiankun Zhang, Chunhui Yang, Fei Xu, Yan Song, Tianen Li, Qiangbo Zhang

“…We analyzed the frequency of FLT3 alterations, its mRNA expression levels, and its prognostic implications across multiple cancer types. Additionally, we explored genes co-expressed with FLT3 and performed gene ontology analysis to identify associated biological processes. …”
Get full text

Urban and Rural Differences in Cancer Treatment Disruption Among Patients With COVID‐19: An Analysis of the US ASCO COVID‐19 in Oncology Registry by Yu Chen Lin, Kea Turner, Oliver T. Nguyen, Emma Hume, Marlene Camacho‐Rivera, Jessica Y. Islam

“…Controlling for other factors, receiving care in a rural oncology practice was associated with cancer TDD (aPR: 1.25, 95% CI: 1.01–1.55). Differences in cancer TDD were not found across rurality of patient residence. …”
Get full text

Temporal and Spatial Characteristics and Influencing Factors of Carbon Storage in Black Soil Area Under Topographic Gradient by Zhaoxue Gai, Wenlu Zheng, Bonoua Faye, Hongyan Wang, Guoming Du

“…Carbon storage was dominant at elevation I (range is 0–200 m), slope I (range is 0–2°), and relief amplitude I (range is 0–30 m). Additionally, the carbon storage losses were severe at elevation II (range is 200–500 m), slope II (2–6°), and relief amplitude II (30–70 m). …”
Get full text

A descriptive analysis of a medical humanitarian aid initiative for quality perinatal management in war-torn Ukraine by Iryna Mogilevkina, Dmytro Dobryanskyy, Rhona MacDonald, Diane Watson, David Southall

“…After informed consent, mothers (n = 13735) who agreed to use in labour fetal self-monitoring in addition to standard intrapartum fetal health surveillance, monitored and recorded fetal heart rate changes on a “contraction-by-contraction” basis into a special form. …”
Get full text

Accommodative Exercises to Lower Intraocular Pressure by Thomas J. Stokkermans, Jeremy C. Reitinger, George Tye, Chiu-Yen Kao, Sangeetha Ragupathy, Huachun A. Wang, Carol B. Toris

“…Three different tests were performed in random order: (1) 10 minutes of nonaccommodation (gazing at the target through lenses that allowed clear vision without accommodating), (2) 10 minutes of accommodation (addition of a minus 3 diopter lens), and (3) 10 minutes of alternating between accommodation and nonaccommodation (1-minute intervals). …”
Get full text

Tamarind (<i>Tamarindus indica</i> L.) Components as a Sustainable Replacement for Pork Meat in Frankfurter Sausages by Rafael Sepúlveda F. Trevisan Passos, Camila Cristina A. de Sousa, Mauricio C. A. da Silva, Ana M. Herrero, Claudia Ruiz-Capillas, Carlos Pasqualin Cavalheiro

“…In terms of mineral composition, CT5 showed the highest (<i>p</i> < 0.05) calcium content. Additionally, ST5 and CT5 treatments demonstrated the lowest processing loss values. …”
Get full text

Development and Evaluation of a Deep Learning–Based Pulmonary Hypertension Screening Algorithm Using a Digital Stethoscope by Ling Guo, Nivedita Khobragade, Spencer Kieu, Suleman Ilyas, Preston N. Nicely, Emmanuel K. Asiedu, Fabio V. Lima, Caroline Currie, Emileigh Lastowski, Gaurav Choudhary

“…Each 15‐second PCG, recorded using a digital stethoscope, was processed to generate 5‐second mel‐spectrograms. An additional labeled data set of 196 patients was used for testing. …”
Get full text