Complete metabolic response as early predictor of long-term efficacy after adoptive T cell therapy using tumor-infiltrating lymphocytes by Rikke Andersen, Troels Holz Borch, Eva Ellebaek, Inge Marie Svane, Helle Westergren Hendel, Kasper Madsen

“…These patients might benefit from additional consolidating treatment before clinical progression, but thus far, it is not possible to identify this subgroup of patients prone to progress. …”
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Contralateral Posterior Chamber Phakic Intraocular Lens Implantation as Rehabilitation of Refractive Lens Exchange with a Monofocal Intraocular Lens in a Young, Nonpresbyopic, Bila... by Kepa Balparda, Claudia Marcela Vanegas-Ramírez, Laura Segura-Muñoz, Manuela Gómez-Londoño

“…RLE in young pre-presbyopic highly myopic patients may not be an advisable alternative in most cases, because of the high risks of retinal complications observed. In addition, eliminating accommodation will cause significant limitations, and multifocal IOLs currently available are far from the quality of vision that a young human crystalline lens yields. …”
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High-Intensity Interval Training Improves Physical Function, Prevents Muscle Loss, and Modulates Macrophage-Mediated Inflammation in Skeletal Muscle of Cerebral Ischemic Mice by Lu Luo, Meixi Liu, Hongyu Xie, Yunhui Fan, Jingjun Zhang, Li Liu, Yun Li, Qiqi Zhang, Junfa Wu, Congyu Jiang, Yi Wu

“…Furthermore, HIIT was superior to MOD in terms of reducing lipid accumulation, levels of IL-1β and IL-6 in paretic gastrocnemius, and improving peripheral blood CD4+/CD8+ T cell ratio, level of IL-10. Additionally, RNA-seq analysis revealed that the differentially expressed genes among HIIT, MOD, and MCAO groups were highly associated with signaling pathways involved in inflammatory response, more specifically the I-kappaB kinase/NF-kappaB signaling. …”
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Biomechanical simulation of bed turning post-acetabular fracture fixation by Haiyang Wu, Zaijie Sun, Qixiao Shen, Xuejian Wu, Cheng Li, Xianhua Cai

“…Group C demonstrated notably lower torsional stiffness (1.51 ± 0.20) relative to Group A (2.33 ± 0.25, P < 0.05) and Group B (2.21 ± 0.29, P < 0.05). Additionally, the medial displacement of the quadrilateral plate was significantly reduced in Group B compared to Group C at all measured time points (P < 0.05). …”
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Prospective cohort study of voice outcomes following secondary tracheoesophageal puncture in gastric pull-up reconstruction after total laryngopharyngoesophagectomy by Emily C. Deane, Harman Parhar, Linda Rammage, Amanda Hu, Donald W. Anderson

“…Speech intelligibility was assessed in a blinded fashion using a validated 7-point scale. Additionally, the Voice Handicap Index-10 was administered as a validated patient self-reporting tool. …”
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Genetic markers of children asthma: predisposition to disease course variants by M. V. Smolnikova, Ed. W. Kasparov, M. A. Malinchik, K. V. Kopylova

“…The AA genotype of IL17A rs2275913, the TT genotype of IFNG rs2069705 and allelic A variants of TNFA rs1800629 are associated with mild asthma, and the TT genotype of IFNG rs2069705 is additionally associated with controlled asthma. The results obtained will supplement information on the prevalence of polymorphic variants of the cytokine genes in the Russian population and in asthma patients with different disease courses, which is likely to be used in order to shape a plan for Public Health Authority to prevent the development of severe uncontrolled asthma and to optimize personalized therapy.…”
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The study of pubertal stage and age of menarche in girls in Isfahan province, Iran by Nafiseh Mozafarian, Mahin Hashemipour, Mohammad Reza Maracy, Masoumeh Pourrajab, Razieh Omidi, Roya Kelishadi

“…Trained physicians determined the breast development through both visual inspection and palpation, in addition, mothers assessed their daughter’s pubic hair growth using Tanner’s Sexual Maturation Scale (SMS) by comparison to standard pictures. …”
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Diagnostic accuracy of human papillomavirus testing on self-collected samples among women referred for colposcopy by ChunX Yan, Jiong Ma, Xia Zheng, Jing Shu, XiaoJ Wang, XiaoY Chen, Feng Gao, XiaoQ Li, ShanQ M, LongM Huang, XiaoT Yu, XueJ Chen

“…It may be an alternative option for cervical cancer screening. Additional studies are still required to substantiate this issue.…”
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Divergent values and perspectives drive three distinct viewpoints on grizzly bear reintroduction in Washington, the United States by Tara S. Easter, Anna R. Santo, Abigail H. Sage, Neil H. Carter, Kai M. A. Chan, Jason I. Ransom

“…Our analysis underscores the need to identify and attend to latent viewpoints that may be overlooked in the polarized public discourse as well as the multiple value systems and perceptions of risk that are integrated in perspectives on grizzly bear reintroduction. Additionally, our broadly defined identity groups were of very little utility in predicting viewpoints in this study, highlighting the importance of avoiding assumptions about people's views based on their identities and interests. …”
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Prediction models of iron level in beef muscle tissue toward ecological well-being by K. Narozhnykh

“…BACKGROUND AND OBJECTIVES: Elemental status is associated with the biochemical processes occurring in the body. Beef, consumed worldwide, is an excellent source of iron in terms of quantity and bioavailability, providing up to 18 percent of the daily requirement. …”
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Fluid flow in crustal fault zones with varying lengthwise thickness: application to the Margeride fault zone (French Massif Central) by Emmy Penhoët, Laurent Arbaret, Laurent Guillou-Frottier, Hugo Duwiquet, Charles Gumiaux, Mathieu Bellanger

“…Depending on the permeability value, an additional anomaly may develop but will migrate laterally towards the thinnest part of the fault zone. …”
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A tendency towards leaf rust resistance decrease in common wheat introgression lines with genetic material from Aegilops speltoides Tausch by L. Ya. Plotnikova, L. V. Meshkova, E. I. Gultyaeva, O. Р. Mitrofanova, I. F. Lapochkina

“…Presumably, the rest of samples possess additional not yet identified genes of Ae. speltoides. …”
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Differential Regulation of Methylation-Regulating Enzymes by Senescent Stromal Cells Drives Colorectal Cancer Cell Response to DNA-Demethylating Epi-Drugs by Khushboo Agrawal, Viswanath Das, Natálie Táborská, Ján Gurský, Petr Džubák, Marián Hajdúch

“…Similar to 2D cultures, senescent fibroblasts increased DNA demethylation of CRC cells in coculture spheroids, in addition to increasing the stemness of CRC cells. This study presents the first evidence of the effect of normal and senescent stromal cells and their conditioned medium on DNA demethylation by DAC. …”
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Genetic methods in honey bee breeding by M. D. Kaskinova, A. M. Salikhova, L. R. Gaifullina, E. S. Saltykova

“…Based on the data obtained, a scheme was developed for obtaining primary material for honey bee breeding, which can subsequently be subjected to selection according to economically useful traits. In addition, the annual assessment of the allelic diversity of the csd gene will shed light on the frequency of formation of new allelic variants and other issues related to the evolution of this gene.…”
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Improvement of engineering properties and environmental impact of fired clay bricks utilizing industry sludge waste by Amir Detho, Aeslina Abdul Kadir, Ahmad Shayuti, Bin Abdul Rahim, Nejib Ghazouani, Abdelkader Mabrouk, Ahmed Babeker Elhag, Hesham Hussein Rassem

“…Incorporating up to 30% of body mill sludge (BS) and polishing sludge (PS) into the brick mix significantly enhances physical and mechanical properties, resulting in reduced shrinkage, increased porosity, and improved compressive strength, reaching up to 25 N/mm². …”
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Anterior skull base reconstruction using nasoseptal flap: cadaveric feasibility study and clinical implication [SevEN-001] by Kyoung Su Sung, Jaejoon Lim, Minkyun Na, Sanghun Lee, Ju-Seong Kim, Je Beom Hong, Chang-Ki Hong, Ju Hyung Moon

“…When possible, by leaving some portion of the anterior sphenoid wall for supporting the PNSF, successful ASB reconstruction could be achieved in endoscopic resection of ASB tumors. Additional methods might be needed in some cases of large ASB lesions wherein the anterior sphenoid wall should be removed totally and the ASB defect is too large.…”
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Impact of fetal sex on neonatal outcomes in women with gestational diabetes mellitus: a systematic review and meta-analysis by Mahsa Maghalian, Zohreh Alizadeh-Dibazari, Mojgan Mirghafourvand

“…Sensitivity analyses were performed using the leave-one-out approach to evaluate the robustness of the pooled results. Additionally, a meta-regression analysis was conducted, considering maternal age, gestational weight gain, and BMI for both male and female infants. …”
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Prevalence of Pulmonary Embolism in COVID-19 Positive Critically Ill Children by Yudy Fonseca, MD, Alise Davies, PA, Stephanie Jarrin, MD, Liliana Simon, MD, Cortney Foster, DO, Sun Kai, Adnan Bhutta, MD

“…Our study indicates that COVID-positive patients are 4.8 times more likely to develop PE than COVID-negative patients. Additionally, the study highlights substantial racial disparities in the prevalence of PE, with Black or African American patients being disproportionately affected.…”
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Color, Structure, and Thermal Stability of Alginate Films with Raspberry and/or Black Currant Seed Oils by Jolanta Kowalonek, Bogna Łukomska, Aleksandra Szydłowska-Czerniak

“…The shape of the thermogravimetric curves did not depend on the oil type. The added oils reduced the efficiency of alginate decomposition in the first stage. …”
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Novel green synthesis of silver nanoparticles from empty fruit bunch waste: Biomedical applications and mechanistic insights by Bashirat Olamide Yusuf-Salihu, Shakirat Afodun Abdulmumini, Toheeb Taiye Bajepade, Halimah Adekunbi Durosinmi, Muinat Olanike Kazeem, Victoria Atinuke Ajayi, Agbaje Lateef

“…Furthermore, EFB-AgNPs prevented blood coagulation and dissolved blood clots. In addition, EFB-AgNPs inhibited α-amylase with 74.64 % at 100 µg/ml. …”
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