Effects of Nutritional Status During Sexual Maturation and Resource Availability on the Resource Allocation of Females in Burying Beetles by Wenxia Wang, Guojun Zhou, Wei Zhang, Kai Tian, Lunguang Yao

“…Finally, our findings suggest that poor‐fed females did not suffer a future cost in offspring performance. …”
Get full text

Treatment of inoperable pancreatic adenocarcinoma with focused ultrasound and microbubbles in patients receiving chemotherapy by Margrete Haram, Rune Hansen, Ola Finneng Myhre, Stian Solberg, Naseh Amini, Bjørn Atle Angelsen, Catharina de Lange Davies, Eva Hofsli

“…Results: Treatment with FUS and MB is safe with the used settings. No additional effects of FUS and MBs regarding tumor volume or resectability were observed. …”
Get full text

An Objective Pain Score for Chronic Pain Clinic Patients by Agnes K. Pace, Melanio Bruceta, John Donovan, Sonia J. Vaida, Jill M. Eckert

“…Meanwhile, objective pain scales utilize, for the most part, the patient’s behavioral component as observed by the provider in addition to the patient’s subjective perception of pain. …”
Get full text

TGFβ-specific T cells induced by a TGFβ-derived immune modulatory vaccine both directly and indirectly modulate the phenotype of tumor-associated macrophages and fibroblasts by Mads Hald Andersen, Inés Lecoq, Evelina Martinenaite, Maria Perez-Penco, Lucia Lara de la Torre

“…TAMs tend to have tumor-promoting functions, harbor an immunosuppressive phenotype and are linked to decreased overall survival in pancreatic cancer when they harbor an M2-like phenotype. In addition, myofibroblast-like CAFs create a stiff extracellular matrix that restricts T cell infiltration, impeding the effectiveness of immune therapies in desmoplastic tumors, such as pancreatic ductal adenocarcinoma. …”
Get full text

Evaluation of the Education Plan and Activities of Swiss Sport Integrity. A report of a science-practice co-operation. by Christoffer Klenk, Jonas Personeni

“…The questionnaires were conducted during the year as part of the SSI education courses, which are mandatory for all Swiss elite athletes. Additionally, internal data from SSI and Swiss Olympic were gathered. …”
Get full text

Astaxanthin-loaded brain-permeable liposomes for Parkinson’s disease treatment via antioxidant and anti-inflammatory responses by Thai-Duong Nguyen, Shristi Khanal, Eunhee Lee, Jinsol Choi, Ganesh Bohara, Nikesh Rimal, Dong-Young Choi, Soyeun Park

“…Lf-functionalized liposomes demonstrated enhanced cellular uptake and permeation in a Transwell® study, showing a 16.7-fold higher internalization in SH-SY5Y cells over 24 h than those without Lf conjugation. Additionally, Lf functionalization enhanced brain penetration ability, as demonstrated by a biodistribution study using nude mice, compared to LPs without Lf conjugation. …”
Get full text

Adherence to First-Line Intravesical Bacillus Calmette-Guérin Therapy in the Context of Guideline Recommendations for US Patients With High-Risk Non-muscle Invasive Bladder Cancer by Franklin D. Gaylis, Bruno Emond, Ameur M. Manceur, Anabelle Tardif-Samson, Laura Morrison, Dominic Pilon, Patrick Lefebvre, Lorie A. Ellis, Hiremagalur Balaji, Andrea Ireland

“…**Conclusions:** Results emphasize the need for additional treatment options for patients with NMIBC.…”
Get full text

Childhood socioeconomic background and elevated mortality among the young adult second generation in Sweden: a population-based cohort study by Lisa Harber-Aschan, Matthew Wallace, Ben Wilson, Eleonora Mussino, Siddartha Aradhya

“…Introduction The native-born children of migrants represent one of the fastest-growing and most diverse young populations in the world today. A growing body of research highlights an elevated young adult mortality risk in this ‘second generation’ (G2) relative to the majority population at the same ages. …”
Get full text

Repurposing the Antidiabetic Drugs Glyburide, Gliquidone, and Glipizide in Combination with Benznidazole for <i>Trypanosoma cruzi</i> Infection by Citlali Vázquez, Rusely Encalada, Isabel Jiménez-Galicia, Rogelio Gómez-Escobedo, Gildardo Rivera, Benjamín Nogueda-Torres, Emma Saavedra

“…Remarkably, the antidiabetic drugs in monotherapy decreased the infection in mice by 40–60% in a similar extent to BNZ (80%). In addition, the combination of BNZ plus antidiabetics perturbed the antioxidant metabolites in epimastigotes. …”
Get full text

Anthropological Dimension of the Philosophical "Literature-Centric" Model of Ukrainian Romanticism by Z. O. Yankovska, L. V. Sorochuk

“…Ukrainian writers, reflecting the philosophical ideas of Romanticism, saw in man a harmonious combination of "natural" and "social", through which he indirectly carries out his own national existence. In addition to the objective realities of the external world, in their works, Romantic writers appeal to the subjective, internal, spiritual, "ideal" world of the hero, who interacts with reality through his own system of values. …”
Get full text

Enhancing detection of STEC in the meat industry: insights into virulence of priority STEC by Mai-Lan Tran, Sabine Delannoy, Patrick Fach

“…Recently the updated MLG5C reference method introduced additional genetic markers (espK, espV) in the detection scheme to improve specificity and effectiveness of priority STEC detection in foodstuffs. …”
Get full text

Bone Density, Geometry, and Mass by Peripheral Quantitative Computed Tomography and Bone Turnover Markers in Children with Diabetes Mellitus Type 1 by Maciej Jaworski, Elżbieta Wierzbicka, Edyta Czekuć-Kryśkiewicz, Paweł Płudowski, Maria Kobylińska, Mieczysaw Szalecki

“…Studies on the lower leg in children with T1DM by pQCT have generated conflicting results, and most of the studies published so far focused only on a selected features of the bone. An additional information about growth, modelling, and remodelling processes can be gathered by the bone turnover marker measurement. …”
Get full text

Dietary DHA Regulated the Androgen Production in Male Chinese Tongue Sole Cynoglossus semilaevis by Jiahao Liu, Qiang Ma, Feiran Zhang, Qingyan Gao, Zhijun Zhang, Yuliang Wei, Mengqing Liang, Houguo Xu

“…A 58-day feeding experiment was conducted, and each diet was fed to triplicate tanks of fish. Additionally, an in vitro study with Leydig’s cells of this species was conducted to validate the in vivo results. …”
Get full text

An Effective Iterative Process Utilizing Transcendental Sine Functions for the Generation of Julia and Mandelbrot Sets by Khairul Habib Alam, Yumnam Rohen, Anita Tomar, Naeem Saleem, Maggie Aphane, Asima Razzaque

“…Moreover, we apply <i>s</i>-convexity to the iteration procedure to construct orbits under convexity conditions, and we present a theorem that determines the condition when a sequence diverges to infinity, known as the escape criterion, for the transcendental sine function <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mo form="prefix">sin</mo><mo>(</mo><msup><mi>u</mi><mi>m</mi></msup><mo>)</mo><mo>−</mo><mi>α</mi><mi>u</mi><mo>+</mo><mi>β</mi></mrow></semantics></math></inline-formula>, where <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>u</mi><mo>,</mo><mi>α</mi><mo>,</mo></mrow></semantics></math></inline-formula><inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>β</mi><mo>∈</mo><mi mathvariant="double-struck">C</mi></mrow></semantics></math></inline-formula> and <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>m</mi><mo>≥</mo><mn>2</mn></mrow></semantics></math></inline-formula>. Additionally, we generate chaotic fractals for this orbit, governed by escape criteria, with numerical examples implemented using MATHEMATICA software. …”
Get full text

Relationship between multiple morbidities and performance on the Timed Up and Go test in elderly patients: a cross-sectional study by Arsalan Tariq, Sayed Alireza Mousavi Zadeh, Muhammad Ammar, Nafisehsadat Mousavizadeh, Arash Hajary, Somayeh Mohamadi

“…All analyses were performed using SPSS software.Results A total of 160 participants (mean age: 67.2±6.9 years and body mass index (BMI): 28.7±4.9 kg/m²) were included. …”
Get full text

Association between early‐stage diabetic nephropathy and the delayed monophasic glucose peak during oral glucose tolerance test in type 2 diabetes mellitus by Han Zhang, Hanqing Tang, Yunjuan Gu, Zhuqi Tang, Xiaoqin Zhao, Ranran Zhou, Ping Huang, Rongping Zhang, Xinlei Wang

“…In logistic regression, ISSI‐2 was independently associated with the delay in glucose peak time in patients with T2DM (OR 0.839; 95% CI 0.776–0.907; P < 0.001). Additionally, 2‐h plasma glucose, OGIS, and AUCC‐peptide0–180 min were independently associated with delayed peak glucose time (all P < 0.001). …”
Get full text

Prevalence and immunopathologic characteristics of seropositive and seronegative hepatitis B virus-associated membranous nephropathy: a retrospective study of 420 biopsy-proven cas... by Haitao Lu, Qianqian Xu, Guming Zou, Hongmei Gao, Yue Yang, Wenge Li, Li Zhuo

“…The anti-PLA2R antibody-positive group displayed higher levels of urine protein (p < .05), serum cholesterol (p < .01), and IgG4 subtypes (p < .05) compared to the negative group. Additionally, the positive group had significantly lower levels of serum albumin and IgG than the negative group (p < .01).Conclusions This comprehensive study reveals a significantly higher prevalence of seronegative HBV-MN than previously thought. …”
Get full text

Effects of Whey Protein Concentrate on the Bioaccessibility and Microstructure of 5-Methyltetrahydrocalcium Folate in Simulated Digestive Environment in Vitro by Yusong ZHANG, Weiran CUI, Zhenyue TANG, Hongyu BAI, Meili SHAO

“…According to the findings, 5-MTHF could be securely wrapped, shielded by WPC throughout the stomach stage of digestion, and then moved to the small intestine for full release. Additionally, during the digestive process, the bioaccessibility of WPC-5-MTHF tended to rise in all groups. …”
Get full text

No microorganism was detected in amniotic fluid of healthy pregnancies from the second trimester to the delivery by Yu Liu, Jingmei Ma, Xiang Li, Haijuan Zhao, Qubo Ai, Lanying Zhang, Yulong Tong, Lingzhen Meng, Huixia Yang

“…Cohort 2 contained 22 women who experienced infection-related adverse pregnancy outcomes (including preterm birth, histological chorioamnionitis, and stillbirth), with only their second trimester AF samples (n = 24) examined. Additionally, multiple procedural negative controls and technical positive controls were applied to this study to remove potential contamination. …”
Get full text

Sign Language Recognition System for Deaf Patients: Protocol for a Systematic Review by Milena Soriano Marcolino, Lucca Fagundes Ramos Oliveira, Lucas Rocha Valle, Luiza Marinho Motta Santa Rosa, Zilma Silveira Nogueira Reis, Thiago Barbabela de Castro Soares, Elidéa Lúcia Almeida Bernardino, Raniere Alislan Almeida Cordeiro, Raquel Oliveira Prates, Mario Fernando Montenegro Campos

“…A PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analysis) flow diagram will be presented to visually summarize the screening process, ensuring clarity and transparency in presenting the results. Additionally, a comprehensive chart table will be constructed to consolidate essential data related to the key variables extracted from the studies. …”
Get full text