A tannic acid-based intumescent flame retardant for improving flame retardancy of epoxy composites by Xiaosui Chen, Yaoting Ma, Shuzheng Liu, Aiqing Zhang, Wei Liu, Shengchao Huang

“…More importantly, it reached a high LOI value of 30.3% and passed a V-0 rating in the UL-94 burning test. Additionally, its peak heat release rate (PHRR), total heat release (THR) and average mass loss rate (av-MLR) decreased by 23.2%, 15.5% and 30.2% respectively. …”
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Delta-Like-1 Changes the Immunomodulatory Property of OP9 Cells by Lei Zhang, Rui-Jie Dang, Yan-Mei Yang, Dian-Chao Cui, Ping Li, Yan-Li Ni, Tong Hao, Changyong Wang, Xiao-Xia Jiang, Nan-Zhu Fang

“…DL1 overexpression alone changed the properties of OP9 cells in addition to their role in early B cell development.…”
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Multiple pathways to evaluate the immunoprotective effect of Turkeys Herpesvirus recombinant vaccine expressing HA of H9N2 by Wenhao Yang, Jin Zhang, Jing Dai, Mengjiao Guo, Xiaolong Lu, Ruyi Gao, Kaituo Liu, Min Gu, Shunlin Hu, Xiufan Liu, Xiaoquan Wang, Xiaowen Liu

“…However, in-ovo injection of HVT-HA resulted in significantly higher neutralizing antibodies in the Harderian glands. In addition, it significantly inhibited viral shedding after intranasal exposure to H9N2. …”
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Prevalence, incidence and determinants of QuantiFERONTM positivity in South African schoolchildren by J. Stewart, N. Walker, K. Jennings, C. Delport, J Nuttall, A.K. Coussens, R Dyers, D.A. Jolliffe, J.C.Y. Tang, W.D. Fraser, R.J. Wilkinson, L.-G. Bekker, A.R. Martineau, K. Middelkoop

“…RESULTS: QuantiFERON-positivity at baseline (prevalence: 22.6%, 95% CI 20.9–24.4), was independently associated with increasing age (aOR 1.24 per additional year, 95% CI 1.15–1.34) and household exposure to TB during the participant’s lifetime (aOR 1.87, 95% CI 1.46–2.40). …”
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Intersection of rare pathogenic variants from TCGA in the All of Us Research Program v6 by Blaine A. Bates, Kylee E. Bates, Spencer A. Boris, Colin Wessman, David Stone, Justin Bryan, Mary F. Davis, Matthew H. Bailey

“…With the advent of combining medical records and genetic mutations, we also performed a phenome-wide association study (PheWAS) to assess the effect of pathogenic variants on additional phenotypes. This analysis again showed several associations between predisposition variants and cancer in EUR-like participants, but fewer in those of the other genetic similarity groups. …”
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A Secure and Robust Machine Learning Model for Intrusion Detection in Internet of Vehicles by Pradeep Kumar Tiwari, Shiv Prakash, Animesh Tripathi, Tiansheng Yang, Rajkumar Singh Rathore, Manish Aggarwal, Narendra Kumar Shukla

“…However, the other models achieved mean values ranging from 0.90 to 0.98 across these metrics. Additionally, the proposed model achieved an exceptionally low mean error rate of 0.00001, while the error rates of the other models ranged from 0.02 to 0.05. …”
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Three local plants adapt to ecological restoration of abandoned lead-zinc mines through assembly of rhizosphere bacterial communities by Wei Gao, Shuyi Chen, Xin Yu, Sumin Chen, Caijing Wan, Ying Wang, Peng Wu, Qiang Li

“…Following the planting of the three types of ecologically restored plants, the soil bacterial community structure partially recovered. In addition, different plants have been found to have different functions in the lead-zinc ecological restoration process, including iron complex transport system-permitting proteins and ATP binding cassettes.DiscussionThis study confirms for the first time that plants adapt to the remediation process of abandoned lead-zinc mines by non-randomly assembling rhizosphere bacterial communities and functions, providing a reference for screening microbial remediation bacterial resources and plant microbe joint bioremediation strategies for lead-zinc mines.…”
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RNA-Targeting CRISPR/CasRx system relieves disease symptoms in Huntington’s disease models by Yingqi Lin, Caijuan Li, Yizhi Chen, Jiale Gao, Jiawei Li, Chunhui Huang, Zhaoming Liu, Wei Wang, Xiao Zheng, Xichen Song, Jianhao Wu, Jiaxi Wu, Oscar Junhong Luo, Zhuchi Tu, Shihua Li, Xiao-Jiang Li, Liangxue Lai, Sen Yan

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Intercropping of Saccharum spp. with Dictyophora indusiata: effects on microbial communities and metabolite profiles during bagasse degradation by Mingzheng Duan, Mingzheng Duan, Xiaojian Wu, Shengfeng Long, Hairong Huang, Xiang Li, Yijie Li, Changning Li, Bin Feng, Jiafu Chen, Defa Zhong, Zhendong Chen, Zeping Wang

“…Key metabolites, such as glucose, cellobiose, and D-mannose, were more abundant in DIBA samples. In addition, unique metabolites such as L-alanine, serine, and oxaloacetate were detected in the DIBA treatment, suggesting more efficient bagasse degradation compared with natural processes.ConclusionThe use of macrofungi such as D. indusiata can play a pivotal role in circular agriculture by transforming agricultural waste into valuable soil amendments. …”
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Bexarotene-induced hypothyroidism and dyslipidemia; a nation-wide study by Katsunori Manaka, Junichiro Sato, Yusuke Hikima, Hirofumi Horikoshi, Maho Taguchi, Akimichi Morita, Hiraku Suga, Hikari Boki, Taku Fujimura, Yoji Hirai, Takatoshi Shimauchi, Chiharu Tateishi, Eiji Kiyohara, Ikko Muto, Hideki Nakajima, Riichiro Abe, Kazuyasu Fujii, Chikako Nishigori, Eiji Nakano, Kentaro Yonekura, Takeru Funakoshi, Masahiro Amano, Tomomitsu Miyagaki, Reiko Yamashita, Makoto Sugaya, Toshihisa Hamada, Masaomi Nangaku, Taroh Iiri, Noriko Makita

“…Triglycerides (TG) increased in a bexarotene dose–dependent manner, and grade ≥3 AEs on hypertriglyceridemia was observed in 39% of the patients. Additionally, one-third of grade ≥3 AEs on hypertriglyceridemia occurred within 1 week. …”
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A Comparative Analysis of the Water Retention Properties of Hydrogels Prepared from Melon and Orange Peels in Soils by Shiwei Fang, Yuan Zhong, Jun Wu, Yufan Xie, Liqun Cai, Minjun Li, Jun Cao, Hejie Zhao, Bo Dong

“…The objective of this study was to conduct a comparative analysis of the performance of hydrogels prepared from two distinct raw materials and to identify the hydrogels with the optimal overall capacity for dry farming applications. Ten grafted polymer hydrogels were prepared from melon peel (MP) and orange peel (OP). …”
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Exploiting somatic oncogenic driver alterations in a patient with Li-Fraumeni syndrome– paving the path towards precision medicine: a case report by Carolin Seeling, Sonja Dahlum, Ralf Marienfeld, Vera Jan, Brigitte Rack, Uwe Gerstenmaier, Ambros J. Beer, Regine Mayer-Steinacker, Wolfgang Thaiss, Thomas F. E. Barth, Thomas Seufferlein, Nadine T. Gaisa, Stephan Stilgenbauer, Wolfgang Janni, Reiner Siebert, Hartmut Döhner, Verena I. Gaidzik

“…Conclusions In the era of accessible and comprehensive genetic and phenotypic tumor profiling, this case study of a patient with Li-Fraumeni syndrome underscores the success of precision oncology in harnessing additional somatic oncogenic driver alterations. Furthermore, it emphasizes the indispensable role of an interdisciplinary molecular tumor board, enhancing the awareness of molecular profiling and targeted therapies in patients with rare cancer susceptibility disorders.…”
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BTS1-knockout Saccharomyces cerevisiae with broad-spectrum antimicrobial activity through lactic acid accumulation by Liu Cong, Yuan Zhou, Yu Zhang, Shanshan Mao, Chaoqun Chen, Liying Wang, Xiao Li, Zuo Zhang, Zuobin Zhu, Ying Li

“…Our findings demonstrate its effective inhibition of pathogen growth as evidenced by Minimum inhibitory concentration (MIC) assays, growth curves, bacteriostatic spectrum analyses and co-culture experiments. Additionally, it significantly impedes Escherichia coli and Staphylococcus aureus biofilm formation. …”
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Failure Mechanism and Kinematics of the Deadly September 28th 2016 Sucun Landslide, Suichang, Zhejiang, China by Hai Tian, Jianjun Gan, Hui Jiang, Chun Tang, Changtai Luo, Chenghui Wan, Bin Xu, Faliang Gui, Chengyi Liu, Nian Liu

“…The landslide is controlled by the characteristics of the geological structure, including collapse, circular sliding, plane sliding, and debris flow. In addition, there are rock avalanches on the rear edge of the slope subjected to the combined action of rainfall and gravity. …”
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Non-stationarity analysis of flood extremes under climate change and human activities in the Yuan River Basin, China by Ting Wang, Dehua Mao, Meirong Deng, Chang Feng, Guangwei Hu, Jingya Zhang, Yang Zou

“…Temporal variations were detected and non-stationary models were developed by incorporating physically-based covariates under climate change and human activities using the Mann-Kendall test, Pettitt test, and the Generalized Additive Models for Location, Scale, and Shape (GAMLSS) framework. …”
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Impact of thoracic radiotherapy on first‐line treatment outcomes in ES‐SCLC patients by Xiaoli Mu, Yixin Zhou, Qing Liu, Jiantao Wang, Feng Xu, Feng Luo, Ke Wang, Lu Li, Panwen Tian, Yalun Li, Jiewei Liu, Yan Zhang, Jiyan Liu, Yan Li

“…Remarkably, patients who received tRTdemonstrated superior OS and PFS in comparison to those who did not (P < 0.05). Subgroup analysis further confirmed these findings. …”
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Soil Surface Roughness in Temperate Forest During SMAPVEX19-22 by Victoria A. Walker, Michael H. Cosh, William A. White, Andreas Colliander, Victoria R. Kelly, Paul Siqueira

“…Two experimental methods (handheld lidar and ultrasonic robot) were additionally tested at select sites. After removal of topographic slope, the forest floor was found to be relatively smooth with average rms heights of <inline-formula><tex-math notation="LaTeX">$9+-1 \,{\mathrm{mm}}$</tex-math></inline-formula> in the central Massachusetts domain and <inline-formula><tex-math notation="LaTeX">$6+-1 \,{\mathrm{mm}}$</tex-math></inline-formula> in the Millbrook, New York domain. …”
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Worldwide variations in the knowledge and use of fluoroscopy during percutaneous nephrolithotomy—should we do better? A survey by the European Association of Urology Section for Ur... by Otaš Durutovic, Guohua Zeng, Bhaskar Somani, Simon Choong, Giorgio Mazzon, Di Gu, Zeeshan Hameed, TP Rajeev, Bogomir Milojevic, Davide Brusa, Tiago Ribeiro Oliveira, Sergio Pereira, Nariman Gadzhiev, Ali Serdar Gozen, Evangelos Liatsikos, Panagiotis Kallidonis, Uros Bumbasirevic, Andreas Skolarikos

“…Precautions to reduce exposure appeared poorly followed as up to 25.4% of respondents used regularly continuous fluoroscopy, and up to 20.5% used regularly high-frequency setting and this trend was more obvious among senior specialists (6.2% of trainees used high-frequency settings vs. 21.3% of consultants, p<0.05). Additionally, only 24.9% of respondents would provide X-ray protection to patients too. …”
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A Review of the Health Impact of Nicotine Pouches by Radosław Chmiel, Daria Michałka, Natalie Papachristoforou, Zuzanna Gałuszka, Monika Makar, Tomasz Bartuś, Natalia Tekiela, Emilia Bąk, Justyna Głowacka, Aleksandra Kocjan

“…Snus has been associated with a modest increase in cardiovascular disease risk, although the risks are lower than smoking. Additionally, smokeless tobacco use is linked to an increased risk of oral squamous cell carcinoma, especially in women. …”
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Assessment of clinical prognosis in autoimmune encephalitis: Girona score by Gary Álvarez Bravo, Giuseppe Guglielmini, Ana Quiroga Varela, Almudena Boix Lago, Ariadna Gifreu Fraixinó, Daniele Urso, Daniele Urso, Daniele Urso, Daniele Urso, Giancarlo Logroscino, Giancarlo Logroscino, Giancarlo Logroscino, Giancarlo Logroscino, Lluís Ramió-Torrentà

“…We identified that the mean initial score was significantly higher in the group of patients who had higher mRS at 3 months compared to that in the group of patients who had a mild to moderate disability level (mRS ≤ 2) at 3 months (p = 0.023). In addition, autonomic symptoms and mental status impairment demonstrated to be independent risk factors to predict disability (p &lt; 0.05).ConclusionsThe ACPE-Gi score seems to be a reliable scale for comprehensively evaluating the severity of AE in the acute phase and predicting the risk of disability at 3 months. …”
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