Polymorphisms in immunosuppression-related genes are associated with AML by Mingying Li, Mingying Li, Jingjing Ye, Jingjing Ye, Mengyuan Chang, Mengyuan Chang, Lei Feng, Lei Feng, Tingting Liu, Tingting Liu, Di Zhang, Di Zhang, Yuyan Wu, Yuyan Wu, Yuechan Ma, Yuechan Ma, Guangqiang Meng, Guangqiang Meng, Chunyan Ji, Chunyan Ji, Tao Sun, Tao Sun

“…We then analyzed the relationship between these SNPs and AML susceptibility, treatment response, and prognosis.ResultsOur findings indicated that rs4883263 in the CD163 gene is a protective factor for AML susceptibility and chromosomal karyotype abnormalities. Additionally, rs4883263 in CD163 was related to low PLT count at diagnosis, while rs2272022 in CD200 was protective against low PLT count. rs4780335 in CIITA was associated with high WBC count at diagnosis and worse OS. …”
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Effects of soil management strategies based on different principles on soil microbial communities and the outcomes for plant health by Xing Zhou, Qian Zhang, Yuanyuan Yan, Jisong Qu, Jun Zhou, Jun Zhao, Jinbo Zhang, Zucong Cai, Chuanchao Dai, Xinqi Huang

“…Taken together, our results reveal that physicochemical (CF and HE) and biological strategies (RSD) contribute to plant health via different mechanisms. In addition, this study provides empirical evidence for the significant impact of biological management on the manipulation of the core microbiome and its critical role in plant health.…”
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Long-term exposure to air pollution and lower respiratory infections in a large population-based adult cohort in Catalonia by Anna Alari, Otavio Ranzani, Carles Milà, Sergio Olmos, Xavier Basagaña, Payam Dadvand, Talita Duarte-Salles, Mark Nieuwenhuijsen, Cathryn Tonne

“…We assessed interaction between exposure and clinical and socio-economic factors on multiplicative and additive scales. Results: An interquartile range exposure increase was associated with an 8 % (95 % Confidence Interval: 5 %–11 %) for Nitrogen Dioxide, 10 % (95 % Confidence Interval: 8 %–13 %) for Particulate Matter with diameter equal to or smaller than 2.5 µm, 5 % (95 % Confidence Interval: 3 %–7%) for Particulate Matter with diameter equal to or smaller than 10 µm and 18 % (95 % Confidence Interval: 14 %–22%) for ozone (adjusted by Nitrogen Dioxide) increase in hospital admissions for respiratory infections. …”
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A Comparative Analysis between Ultrasound-Guided and Conventional Distal Transradial Access for Coronary Angiography and Intervention by Shinsuke Mori, Keisuke Hirano, Masahiro Yamawaki, Norihiro Kobayashi, Yasunari Sakamoto, Masakazu Tsutsumi, Yohsuke Honda, Kenji Makino, Shigemitsu Shirai, Yoshiaki Ito

“…However, the rate of PCI, puncture time, total fluoroscopy time, the volume of contrast medium, the rate of access-site ecchymosis, and incidence of nerve disorder were similar between the two groups. Additionally, radial artery occlusion after the procedure did not occur in this study. …”
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A multi-stage deep learning network toward multi-classification of polyps in colorectal images by Shilong Chang, Kun Yang, Yucheng Wang, Yufeng Sun, Chaoyi Qi, Wenlong Fan, Ying Zhang, Shuang Liu, Wenshan Gao, Jie Meng, Linyan Xue

“…Facing a significant class imbalance, particularly in the underrepresented categories of villous and serrated adenomas, we employed Generative Adversarial Network Augmentation (GAN-Aug) to synthesize additional images, thereby ensuring a more balanced dataset for training. …”
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The difference between young and older ducks: Amino acid, free fatty acid, nucleotide compositions and breast muscle proteome by Tiantian Gu, Mingcai Duan, Li Chen, Yong Tian, Wenwu Xu, Tao Zeng, Lizhi Lu

“…The results showed that the amino acid contents of breast muscle in D900 ducks, especially in Asp (umami) and Thr (sweet), were richer than those in D60 ducks. In addition, the levels of guanosine-5′-monophosphate (GMP), inosine-5′-monophosphate (IMP), monounsaturated fatty acid (MUFA; C18:1 t), and polyunsaturated fatty acid (PUFA; C18:2) in D900 ducks were higher than those in D60 ducks. …”
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Concordance of Australian state and territory government guidelines for classifying the healthiness of foods in public settings by Bettina Backman, Meg Adam, Jasmine Chan, Josephine Marshall, Emalie Rosewarne, Gary Sacks, Adrian J Cameron, Miranda R Blake

“…‘Vegetables’ (100%) and ‘sweet snacks and desserts’ (78%) had the highest concordance across guidelines while ‘cold ready-to-eat foods’ (0%) and ‘savoury snacks’ (23%) had the lowest concordance. In addition to differences in classification criteria, discrepancies between guidelines arose from different approaches to grouping of products. …”
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Nano-curcumin Effects on Ischemic Stroke clinical outcomes and Interleukin-6 Levels: Pilot Randomized Clinical Trial by Zeinab Ehtiatkar, Alia Saberi, Samaneh Ghorbani Shirkouhi, Mozaffar Hosseininezhad, Shahrokh Yousefzadeh-Chabok, Yaser Moadabi, Ashkan Karimi, Haniyeh Shadrou Gharani, Sasan Andalib

“…The cerebral infarct volume did not change significantly one week after the treatment with curcumin.  …”
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Spatiotemporal range dynamics and conservation optimization for endangered medicinal plants in the Himalaya by Fu-Lv Liu, Winnie Wanjiku Mambo, Jie Liu, Guang-Fu Zhu, Raees Khan, Abdullah, Shujaul Mulk Khan, Lu Lu

“…We propose establishing additional protected areas in the Himalaya particularly in the western Himalaya for better management and conservation of endangered medicinal plants.…”
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Environmental exposures related to gut microbiota among children with asthma: a pioneer study in Taiwan by Aji Kusumaning Asri, Tsunglin Liu, Hui-Ju Tsai, Jiu-Yao Wang, Chih-Da Wu

“…A generalized additive model was applied to examine associations. …”
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Species of Sulfur in Sour Gas Reservoir: Insights from In Situ Raman Spectroscopy of S–H2S–CH4–H2O System and Its Subsystems from 20 to 250°C by Yifan Yu, Wenxuan Hu, I-Ming Chou, Lei Jiang, Ye Wan, Yiqun Li, Yang Xin, Xiaolin Wang

“…During gas extraction, the decomposition of H2Sn will cause S deposition in pipelines. (3) In addition to S3−, H2Sn could be the intermediate valence S species involved in the TSR reaction.…”
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The Treatment Effect of Plantago Major on Lung Cancer Based on the Computed Tomography and Pathological Findings: A Case Report Study by Saade Abdalkareem Jasim, Bashar Mudhaffar Abdullah, Patricio Yánez-Moretta, Wesam R. Kadhum, Yasser Fakri Mustafa, Enas R. Alwaily, Munther Abosoda, Ali Alsalamy, Sada Ghalib Al-Musawi, Alaa A. Omran

“…Results: The volume of the tumor was reduced by about 62% (based on CT imaging findings) after the treatment with PM. In addition, the laboratory examinations illustrate that ESR and CRP levels reduced remarkably (from 97 mm/h to 24 mm/h for ESR; from 36.8 mg/L to 1.2 mg/L for CRP) after the treatment. …”
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Simultaneous determination of nirmatrelvir, ritonavir, and beta-D-N4-hydroxycytidine in human plasma and epithelial lining fluid using LC-MS/MS and its clinical application to comp... by Wenjing Zhang, Lin Xia, Zhilong Yuan, Mengdan Liu, Yang Jiao, Zhuo Wang

“…By setting target plasma concentrations of 292 ng/mL for nirmatrelvir and 1205 ng/mL for NHC, based on in vitro antiviral 90 % virus inhibitory concentrations (EC90), the drug's molecular weight and its binding to human plasma proteins, we observed that ritonavir-boosted nirmatrelvir had substantially greater rates of achieving target plasma concentrations. Additionally, we monitored epithelial lining fluid in 4 BALF samples from 4 patients and observed that NHC exhibited higher permeability in lung tissue (approximately 20 % higher than nirmatrelvir). …”
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Placement of an elastic, biohybrid patch in a model of right heart failure with pulmonary artery banding by Yasunari Hayashi, Yasunari Hayashi, Seungil Kim, Seungil Kim, Seungil Kim, Taro Fujii, Taro Fujii, Drake Dalton Pedersen, Drake Dalton Pedersen, Takahiro Ozeki, Takahiro Ozeki, Hongbin Jiang, Antonio D’Amore, Antonio D’Amore, Antonio D’Amore, Antonio D’Amore, Antonio D’Amore, William R. Wagner, William R. Wagner, William R. Wagner

“…Left ventricular ejection fraction in the patch group was higher than in the sham group (p < 0.001), right end-systolic pressure was lower (p = 0.045), and tricuspid annular plane systolic excursion improved in the patch group (p = 0.007). In addition, von Willebrand factor expression was significantly greater in the patch group (p = 0.007).ConclusionsThe placement of a degradable, biohybrid patch onto the RV in a right ventricular failure model with fixed afterload improved myocardial output, moderated pressure stress, and was associated with reduced right ventricular fibrosis.…”
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The potential of recycling wool residues as an amendment for enhancing the physical and hydraulic properties of a sandy loam soil by Ahmed Abdallah, Francesca Ugolini, Silvia Baronti, Anita Maienza, Francesca Camilli, Laura Bonora, Francesca Martelli, Jacopo Primicerio, Fabrizio Ungaro

“…Soil bulk density (BD), total porosity (TP), aggregates stability, aggregate size distribution, saturated hydraulic conductivity, and water retention properties were determined under rain conditions, in addition to rainwater balance (storage, percolation and runoff). …”
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Bacterial blood microbiome of Mastomys rodents: implications for disease spill-over at the animal-human interface within the Bushbuckridge-East community, South Africa by Agatha O. Kolo, Agatha O. Kolo, Kelly A. Brayton, Kelly A. Brayton, Nicola E. Collins, Armanda D. S. Bastos, Armanda D. S. Bastos, Armanda D. S. Bastos, Sonja Matthee, Cory A. Gall, Jeanette Wentzel, Jeanette Wentzel, Luis Neves, Luis Neves, Marinda C. Oosthuizen

“…Conventional PCR and sequencing validated the detection of Bartonella spp. with the first confirmation of Bartonella mastomydis infection in Mastomys in South Africa. Additionally, 317 mites, 90 fleas, 10 ticks and eight lice were collected from the rodents, providing evidence of possible vectors of the organisms detected. …”
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İKTİSADİ BÜYÜME OLGUSUNA EKONOMETRİK BİR YAKLAŞIM: “BRIMCH” ÜLKELERİ VE TÜRKİYE ÖRNEĞİ by Mustafa GÖMLEKSİZ, Mehmet ALAGÖZ

“…İktisadi ve sosyal sermayenin gelişimini ve sürdürülebilirliğini, insan kaynağını entelektüel sermayeye dönüştürme süreçleriyle alakalandıran kalkınma ekonomisi içerisinde, üretimin ve milli gelirin artması olarak tanımlanan iktisadi büyümenin de payı göz ardı edilemez. Bu kapsamda, büyüme kuramcıları sıklıkla iktisadi büyümeyi meydana getiren ekonomik faktörleri inceleme ihtiyacı içerisinde olmuşlardır. …”
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Effects of Tremella fuciformis -Derived Polysaccharides with Different Molecular Weight on D-Galactose-Induced Aging of Mice by Donghui Luo, Xiaofei Liu, Jingjing Guan, Guili Jang, Yanglin Hua, Xinfei Zhang, Xiaofei Xu

“…MM exhibited the best anti-aging effect among the TFPs. Additionally, TFPs partially restored the alterations in pH and the total content of short-chain fatty acids (SCFAs) in the colon but exhibited various impacts on the content of the individual SCFAs. …”
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Comparison of plasma start-up with high Z and low Z first wall in WEST by C. Guillemaut, K. Afonin, G. Bodner, J. Bucalossi, Y. Corre, P. Devynck, A. Diallo, M. Diez, N. Fedorczak, A. Gallo, B. Guillermin, V. Lapleigne, R. Lunsford, P. Maget, J. Morales, Ph. Moreau, the WEST Team, the EUROfusion Tokamak Exploitation Team

“…Although visible spectroscopy and bolometry measurements show respectively a strong weakening of the WI line intensity on the limiters and a reduction of radiated power after the changeover, a degradation occurs with the accumulation of plasma exposure. In addition, the different plasma facing elements of the main chamber do not influence equally the radiated power during start-up. …”
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Study protocol of the METAPANC trial - intensified treatment in patients with local operable but oligometastatic pancreatic cancer - multimodal surgical treatment versus chemothera... by Michael Ghadimi, Uwe Pelzer, Marc G. Besselink, Jens Siveke, Ralph Telgmann, Rickmer Braren, Hanneke Wilmink, Marie Crede, Alexander Koenig, Ute Koenig, Sven Thorsten Liffers, Kai Antweiler, Bas Uijterwijk, Hanna Seppanen, Arno Nordin, Pauli Puolakkainen, Olav F. Dajani, Knut Jørgen Labori, Mia Johansson, Svein Olav Bratlie, Tim Friede, Peter Jo

“…To identify patient subgroups that might benefit from multimodal surgical therapy, additional information on tumor genetics could supplement valid parameters. …”
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