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50421
Effect of Praziquantel on Preventing Delayed Infection of <i>Schistosoma japonicum</i> in Buffaloes and Goats
Published 2024-12-01“…In the present study, buffaloes and goats were pretreated with PZQ at various doses (7–25 mg/kg body weight), followed by infection with <i>S. japonicum</i> cercariae. …”
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50422
Rap1 and mTOR signaling pathways drive opposing immunotoxic effects of structurally similar aryl-OPFRs, TPHP and TOCP
Published 2025-01-01“…Aryl organophosphorus flame retardants (aryl-OPFRs), commonly used product additives with close ties to daily life, have been regrettably characterized by multiple well-defined toxicity risks. …”
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50423
Laser-induced breakdown spectroscopy applied to cattle compost for phosphorus quantification
Published 2022-09-01“…Samples were dried at 50°C for dry matter characterization. As a reference method to determine total P concentration, wet digestion and colorimetry were employed. …”
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50424
Development and characterization of a chicory extract fermented by Akkermansia muciniphila: An in vitro study on its potential to modulate obesity-related inflammation
Published 2025-01-01“…It also decreased leptin expression while increasing adiponectin and HSL expression levels in both adipocytes and co-cultures. In addition, C-Akm extract stimulated adiponectin secretion in the co-culture model. …”
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50425
Comparative anti-methanogenic ability of green algae (C. reinhardtii) with/without nanoparticles: in vitro gas and methane production
Published 2025-02-01“…To precisely ascertain the impact particular Rhodophyta on greenhouse gas emissions, additional investigation is needed.…”
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50426
Clonal hematopoiesis in patients with autoimmune thrombocytopenia: an international multicenter study
Published 2025-02-01“…Mutated patients were more frequently older males and showed a shorter time from first to second-line therapy, particularly with thrombopoietin receptor agonist (TPO-RA). Additionally, clonal hematopoiesis was associated with increased thrombotic risk (26% vs 8% in NGS-negative cases; P = .01), independently from TPO-RA exposure, though with an age effect. …”
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50427
Electronic and photophysical properties of copper (II) Complexes: Insights into solvatochromic Effects, Photoreduction, and fluorescence behavior
Published 2025-01-01“…Photolysis experiments underpin the complexes’ behavior under light irradiation, revealing reversible photoreduction processes and the formation of novel photoproducts. Notably, the addition of triethylamine influences photolysis kinetics, elucidating complex interactions. …”
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50428
Working experiences of remote interpreters in health care settings—insights from Austria and Germany
Published 2025-02-01“…We tested this hypothesis using a quantitative approach. Additionally, we analyzed qualitative data to uncover more enabling and hindering factors.MethodsA sample of 87 interpreters working in Austria and Germany was included in this multi-methods study. …”
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50429
Improving dexamethasone drug loading and efficacy in treating rheumatoid arthritis via liposome: Focusing on inflammation and molecular mechanisms
Published 2025-01-01“…The liposomal formulation also shows better hemocompatibility, fewer adverse effects on body weight and immune organ index, and a longer circulation time with higher bioavailability. …”
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50430
Culture-independent detection of Mycobacterium tuberculosis complex DNA using targeted next generation sequencing in African buffalo (Syncerus caffer) oronasal swabs in South Afric...
Published 2025-02-01“…African buffaloes (Syncerus caffer) are wildlife maintenance hosts of Mycobacterium bovis (M. bovis), the causative agent of animal tuberculosis (aTB) in multiple ecosystems across South Africa. In addition to their role as keystone species, these animals are vital to South Africa’s economy as a highly valuable species. …”
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50431
A framework to comprehensively assess lake health from a perspective of ecosystem integrity and services
Published 2025-02-01“…Furthermore, the reference state was carefully selected and used to set the health level and health scores. In addition, a fuzzy binary comparison method was used to assign the optimum weights for each index. …”
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50432
MELK prevents radiofrequency ablation-induced immunogenic cell death and antitumor immune response by stabilizing FABP5 in hepatocellular malignancies
Published 2025-01-01“…Mechanically, MELK binds to fatty acid-binding protein 5 (FABP5), and affects its ubiquitination through the K48R pathway to increase its stability, thereby activating protein kinase B (Akt)/mammalian target of rapamycin (mTOR) signaling axis to weaken the RFA-mediated antitumor effect. In addition, the synthesis of arginylglycylaspartic acid (RGD)-lipid nanoparticles (LNPs) targeting tumor cell-intrinsic MELK enhanced RFA efficacy in HCC. …”
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50433
Identification of two new genetic loci for high-resolution genotyping of Enterocytozoon bieneusi
Published 2025-01-01“…In addition to the ribosomal internal transcribed spacer (ITS) locus, four loci (MS1, MS3, MS4, and MS7) have been identified to develop multilocus sequence typing tools for high-resolution genotyping of Enterocytozoon bieneusi in previous studies. …”
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50434
Adipocyte heterogeneity and tumor infiltration of adipose tissue in patients with metastatic breast cancer
Published 2025-02-01“…Results: Distant adipocyte size did not significantly differ across fat depots. …”
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50435
Investigating the Effect and Potential Mechanism of Rhamnetin 3-<i>O</i>-α-Rhamnoside on Acute Liver Injury In Vivo and In Vitro
Published 2025-01-01“…The hepatoprotective activity of ARR was evaluated by assessing liver morphology, liver function indices, oxidative stress, and the mRNA expression levels of inflammation-related genes in the zebrafish model. Additionally, the ROS level, inflammatory factors, and protein expression related to the IKKβ/NF-κB signaling pathway were measured to investigate a potential mechanism of ARR in HepG2 cells. …”
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50436
Phytochemical screening and neuro-pharmacological activity of Mimosa pudica flowers: Integrating in vitro, in silico and in vivo approaches
Published 2025-02-01“…The extract, given at doses of 200 mg/kg and 400 mg/kg body weight, showed notable effects on neurobehavioral parameters, similar to the conventional medications Diazepam and Escitalopram (1 mg/kg body weight). …”
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50437
Assessing recovery time of ecosystems in China: insights into flash drought impacts on gross primary productivity
Published 2025-02-01“…In this study, we investigate the recovery time patterns in a terrestrial ecosystem in China based on GPP using a random forest regression model and the SHapley Additive exPlanations (SHAP) method. A random forest regression model was developed to analyse the factors influencing recovery time and establish response functions through partial correlation for typical flash drought recovery periods. …”
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50438
Towards equitable carbon responsibility: Integrating trade-related emissions and carbon sinks in urban decarbonization
Published 2025-03-01“…The redistribution of outsourced emissions through supply chains alleviates the mitigation burden on producer cities by 20–30 %. Additionally, accounting for carbon sinks substantially influences CMR allocation, particularly in forest-rich cities, which may see their carbon budgets increase by up to 10 %. …”
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50439
Short path molecular distillation of the essential oil from Pinus roxburghii oleoresin affords volatile fractions with powerful antioxidant and antimicrobial activities comparable...
Published 2025-02-01“…The oil was subsequently separated by short path molecular distillation into fractions and sub-fractions whose antioxidant activity was determined by the DPPH scavenging assay, the inhibition of linoleic acid peroxidation test, the FRAP assay, and the H2O2 scavenging assays. In addition, the antimicrobial activity of the fractions and sub-fractions against the bacteria Pasteurella multocida, Staphylococcus aureus, Escherichia coli, and Bacillus subtilis, and the fungal strains Fusarium solani, Alternaria alternata, Aspergillus flavus, and Aspergillus niger, was measured by the agar well diffusion method, the microdilution broth assay and the resazurin microtiter plate test. …”
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50440
Factors affecting patient satisfaction during endoscopic procedures
Published 2024-01-01“…The study found that the most significant factors affecting patient satisfaction were waiting time to get an appointment (15.5 %), waiting time on the day of the procedure (17.0 %) and pain or discomfort during and after the procedure (15.6 %). Additionally, the personal manner of the physician and nurses, as well as comprehensive explanations before and after the procedure, were also significant factors. …”
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