Hepatocyte-derived liver progenitor-like cells attenuate liver cirrhosis via induction of apoptosis in hepatic stellate cells by Xu Zhou, Wen-Ming Liu, Han-Yong Sun, Yuan Peng, Ren-Jie Huang, Cai-Yang Chen, Hong-Dan Zhang, Shen-Ao Zhou, Hong-Ping Wu, Dan Tang, Wei-Jian Huang, Han Wu, Qi-Gen Li, Bo Zhai, Qiang Xia, Wei-Feng Yu, He-Xin Yan

“…In vitro experiments used HSCs to explore the antifibrotic properties of HepLPC-secretomes and their underlying molecular mechanisms. Additionally, proteomic analysis was conducted to characterize the protein composition of HepLPC-secretomes. …”
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Programmed cell death-related gene IL20RA facilitates tumor progression and remodels tumor microenvironment in thyroid cancer by Yuqi Wang, Yunlong Zhang, Min Liu, Yu Liu, Yu Zeng, Wei Zhang, Shuping Wu, Linfei Hu, Xianhui Ruan, Xiangqian Zheng, Ming Gao, Jingzhu Zhao

“…The function of IL20RA which could potentially provide a foundation for additional investigations into diagnostic markers and treatment targets for THCA.…”
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Impact of Different Metabolic Indicators on Ventricular Repolarization Indices in Obese Children: A Case Control Study by Asmaa A El Sehmawy, Rasha Abd El Samad Fawaz, Nadia Ahmed Agiba, Eman Aziz Elsherbiny, Nglaa Fathi Agaba, Doaa Sayed Mohammed, Haidy Mahmoud Nasr, Fatma Elzhraa AE Diab, Amal M Ahmed, Shorouk Issa Mahfouz, Heba T Okda, Doaa Sadek Ahmed

“…Additionally, no significant difference was revealed between obese children with and without metabolic syndrome regarding ventricular repolarization ECG parameters. …”
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Global and Local Infall in the ASHES Sample (GLASHES). I. Pilot Study in G337.541 by Kaho Morii, Patricio Sanhueza, Timea Csengeri, Fumitaka Nakamura, Sylvain Bontemps, Guido Garay, Qizhou Zhang

“…Using dense gas tracers such as N _2 H ^+ ( J  = 1–0) and HNC ( J  = 3–2), we find signs of infall from the position–velocity diagram and more directly from the blue asymmetry profile in addition to the clump-scale velocity gradient. We estimate infall velocities from intermediate and low-mass cores to be 0.28–1.45 km s ^−1 , and infall rates to be on the order of 10 ^−4 –10 ^−3 M _⊙ yr ^−1 , both are higher than those measured in low-mass star-forming regions by more than a factor of 5 and an order of magnitude, respectively. …”
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Overexpression of HIF-2α, TWIST, and CXCR4 Is Associated with Lymph Node Metastasis in Papillary Thyroid Carcinoma by Ni Wang, Hao-Jun Luo, Guo-Bing Yin, Chao-Ran Dong, Man Xu, George G. Chen, Zhi-Min Liu

“…Additionally, HIF-2α, TWIST, and CXCR4 mRNA expression were assessed in 30 PTCs, 10 nodular hyperplasia, and 10 normal thyroid tissue specimens using real-time RT-PCR. …”
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Assisted Parkinsonism Diagnosis Using Multimodal MRI—The Role of Clinical Insights by Tobias Meindl, Alexander Hapfelmeier, Tobias Mantel, Angela Jochim, Jonas Deppe, Silke Zwirner, Jan S. Kirschke, Yong Li, Bernhard Haslinger

“…Objective To assess whether the performance of classifiers based on imaging derived biomarkers is improved with the addition of basic clinical information and to provide a practical solution to address the insecurity of classification results due to the uncertain clinical diagnosis they are based on. …”
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Electrochemically-driven solid oxide tubular membrane reactor for efficient separation of oxygen and argon by Yuanhui Tang, Yutao Hu, Sisi Wen, Song Lei, Yakai Lin, Li Ding, Haihui Wang

“…The resulting membrane reactor was compact, defect-free, and capable of producing Ar with a purity of 99.99 %. Additionally, under a constant total current of 0.75 A and an operating temperature of 800 °C, the membrane reactor demonstrated stable performance for over 130 hours, maintaining a Faradaic efficiency exceeding 95 %. …”
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A multi‐tagged SAR ocean image dataset identifying atmospheric boundary layer structure in winter tradewind conditions by Chen Wang, Justin E. Stopa, Doug Vandemark, Ralph Foster, Alex Ayet, Alexis Mouche, Bertrand Chapron, Peter Sadowski

“…This strategy extends the TenGeoP‐SARwv by identifying coexisting phenomena within a single SAR image and by the addition of mixed roll/cell states and cold pools. …”
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Lipids in parenteral nutrition – expert consensus statements: Translating guidelines into clinical practice by Robert G. Martindale, Philip C. Calder, Sarah V. Cogle, David C. Evans, Leah Gramlich, Stephen A. McClave, Manpreet S. Mundi, Maurizio Muscaritoli, Reid Nishikawa, Jayshil Patel, Lorenzo Pradelli, Martin Rosenthal, Christian Stoppe, Kelly A. Tappenden, Malissa Warren, Dan Waitzberg, Paul E. Wischmeyer, Stanislaw Klek

“…Summary: Lipids are integral to parenteral nutrition (PN) in all settings where PN is required, serving as a source of energy and essential fatty acids. In addition, lipids modulate a variety of biological functions, including inflammatory and immune responses. …”
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Planned, ongoing and completed tuberculosis treatment trials in Brazil, Russia, India, China and South Africa: a 2019 cross-sectional descriptive analysis by Tamara Kredo, Duduzile Edith Ndwandwe, Lindi Mathebula, Lovemore Mapahla, Dilyara Nurkhametova, Liliya Eugenevna Ziganshina, Mikateko Mazinu, Esme Jordan

“…We included only registered clinical trials conducted wholly in BRICS countries or with at least one recruitment centre in one of the BRICS countries that were investigating TB treatment.Results The search of the WHO-ICTRP yielded 408 trials and additional 32 trials were identified from the Russian registry. …”
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Development of a model for detection and analysis of inclusions in tomographic images of iron castings using decision trees by Dorota Wilk-Kołodziejczyk, Aleksandra Nowotny, Izabela Krzak, Adam Tchórz, Krzysztof Jaśkowiec, Marcin Małysza, Adam Bitka, Mirosław Głowacki, Marzanna Książek, Łukasz Marcjan

“…It cannot be assumed that specific types of defects will occur in the tested object (e.g. only gas porosities), which requires additional analysis of the microstructure image.…”
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Is Everyone Beating Around the Bush?: A Qualitative Study Examining the Status of Shared Decision-Making Between Veterans Affairs Providers and Surgical Patients in the ICU by M. Andrew Millis, MD, MPH, C. Ann Vitous, MA, MPH, Cara Ferguson, BS, Maedeh Marzoughi, BS, Erin Kim, BS, Sarah E. Bradley, PhD, MPH, CPH, Ashley Duby, MS, Pasithorn A. Suwanabol, MD, MS

“…Providers use elements of SDM when caring for critically ill surgical patients. Additionally, this work identifies facilitators that can be leveraged and barriers that can be addressed to facilitate better communication and decision-making through SDM. …”
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Exploring the general practitioners’ perception of the inter-professional care of rheumatoid arthritis patients (GEPRA—II): a qualitative interview study by Anne-Laure Yailian, Audrey Janoly-Dumenil, Emmanuelle Vignot, Aurélie Fontana, Charline Estublier, Cyrille Confavreux, Roland Chapurlat, Claude Dussart, Humbert de Freminville

“…Regarding their perception of the community-hospital relationship, they sometimes considered it insufficient and expected more immediate interactions. Additionally, most interviewed GPs had no expectation regarding increased collaborations with community pharmacists (CPs) and several GPs were motivated to be more involved in a patient support programme. …”
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Correlation Analysis Between Multi-Drug Resistance Phenotype and Virulence Factor Expression of Clinical <i>Pseudomonas aeruginosa</i> by Wenli Xu, Runcheng Zhou, Jingwei Pan, Zhuangcong Liu, Xuyu Huang, Yueqiao Lin, Nan Li, Kecan Chen, Wenbo Sun, Yi Deng, Anping Yang, Xin Chen

“…In addition, biofilm formation was moderately associated with imipenem resistance. …”
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Single-cell sequencing uncovers the mechanistic role of DAPK1 in glioma and its diagnostic and prognostic implications by Tian-Hang Yu, Yan-Yu Ding, Yan-Yu Ding, Si-Guo Zhao, Jie-Hui Zhao, Yu Gu, Dong-Hui Chen, Fang Zhang, Wen-Ming Hong, Wen-Ming Hong

“…However, the precise role and underlying mechanisms of DAPK1 in gliomas remain inadequately understood.MethodsWe performed analyses on RNA-seq and microarray datasets from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO), in addition to single-cell RNA sequencing (scRNA-seq) data from glioma patients available in GEO. …”
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A transgenic cell line with inducible transcription for studying (CGG)n repeat expansion mechanisms by I. V. Grishchenko, A. A. Tulupov, Y. M. Rymareva, E. D. Petrovskiy, A. A. Savelov, A. M. Korostyshevskaya, Y. V. Maksimova, A. R. Shorina, E. M. Shitik, D. V. Yudkin

“…These experimental systems can serve for f inding the causes of instability and the development of therapeutic agents. In addition, a criterion was developed for the quantif ication of exogenous (CGG)n repeat instability in the transgenic cell lines’ genome.…”
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The Observed Phase Space of Mass-loss History from Massive Stars Based on Radio Observations of a Large Supernova Sample by Itai Sfaradi, Assaf Horesh, Rob Fender, Lauren Rhodes, Joe Bright, David Williams-Baldwin, Dave A. Green

“…Furthermore, we rule out mass-loss rates in the range of 2 × 10 ^−6 –10 ^−4 M _⊙ yr ^−1 for different epochs during the last 1000 yr before the explosion (assuming wind velocity of 10 km s ^−1 ) for the progenitors of ~80% of the Type II supernovae (SNe II) in our sample. In addition, we rule out the ranges of mass-loss rates suggested for red supergiants for ~50% of the progenitors of SNe II in our sample. …”
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Silencing hepatic PCSK9 via novel chimeric AAV8 mitigates the progression of atherosclerosis by inhibiting inflammation in ApoE−/− mice by Xiaocui Chen, Minghui Sun, Xiang Ma, Yitong Ma, Bangdang Chen

“…Moreover, it significantly lowered serum cholesterol and triglyceride levels while increasing LDL-R level without causing hepatotoxicity in wild-type mice. Additionally, it decreased PCSK9 expression and elevated low-density lipoprotein receptor expression in Apolipoprotein E-deficient mice, leading to early changes in lipid profiles but lacking a sustained impact on circulating lipids. …”
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Blood Transfusions in Total Hip and Knee Arthroplasty: An Analysis of Outcomes by Thomas Danninger, Rehana Rasul, Jashvant Poeran, Ottokar Stundner, Madhu Mazumdar, Peter M. Fleischut, Lazaros Poultsides, Stavros G. Memtsoudis

“…Patients requiring blood transfusion were significantly older and showed a higher comorbidity burden. In addition, these patients had significantly higher rates of major complications and a longer length of hospitalization. …”
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DR Loss-Free Dithering-Based Digital Background Linearity Calibration for SAR-Assisted Multi-Stage ADCs With Digital Input-Interference Cancellation by Lizhen Zhang, Bo Gao, Kun-Woo Park, Kent Edrian Lozada, Raymond Mabilangan, Hyeongjin Kim, Jianhui Wu, Seung-Tak Ryu

“…We also describe a capacitor-scanning dither method to accomplish simultaneous and independent identification of multiple bit weights. In addition, a digital-domain input-interference cancellation (IIC) technique is proposed to accelerate the convergence speed of the correlation-based calibration. …”
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