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49861
Liposomal Formulations: A Recent Update
Published 2024-12-01“…Surface modification methods like PEGylation and ligand conjugation can direct liposomes to disease regions, improving therapeutic efficacy and reducing off-target effects. In addition to drug loading, researchers have focused on spatiotemporal modulation of liposomal carrier medication release. …”
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49862
Professional and personal experiences of workplace violence among Italian mental health nurses: A qualitative study
Published 2024-12-01“…The aggressions resulted in a change in the nurses' work habits and performances; they were more careful after the aggression and modified their approach to the patient. Additionally, the nurses discussed developing skills and strategies to protect themselves and avoid aggression.ConclusionsAggression has a negative impact on the health and work performance of nurses. …”
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49863
Enhanced Bayesian model for multienvironmental selection of winter hybrids maize: assessing grain yield using ‘ProbBreed’
Published 2025-01-01“…Joint probability analysis identified RMH1899 super (0.23 & 8.3 tons/ha), followed by RMH 666 (0.15 & 8.4 tons/ha) and Uttam 121 (0.11 & 8.6 tons/ha), all of which accounted for overall environmental conditions. Additionally, over the years, DKC 9149, NK 6607(0.18 & 8.6 tons/ha), GK 3254(0.18 & 8.5 tons/ha), Shann 111(0.12 & 8.4 tons/ha), Sweety 1(0.13 & 8.4 tons/ha), and ADV 756(0.10 & 8.2 tons/ha) consistently demonstrated superior performance and stability. …”
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49864
Evaluation of the effectiveness of blood-drop agglutination test for chicken tuberculosis diagnosis
Published 2023-03-01“…The blood-drop agglutination test made it possible to additionally identify 311 adult chickens seropositive for tuberculosis in poultry farms. …”
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49865
Complement activation by in vivo neonatal and in vitro extracorporeal membrane oxygenation
Published 2002-01-01“…We investigated the relative importance of these mechanisms by measuring C3a, C5a and sC5b-9 before, during and after neonatal ECMO in six consecutive newborn patients using enzyme-linked immunoassay. In addition complement activation during in vitro ECMO with repeated flow of the same blood volume was measured using blood from healthy adult donors. …”
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49866
An Optimization Coverage Strategy for Wireless Sensor Network Nodes Based on Path Loss and False Alarm Probability
Published 2025-01-01“…., this may lead to a large gap between the expected effect of actual coverage and simulated coverage. Additionally, these models frequently neglect critical factors such as sensor failures and malfunctions, which can significantly affect signal detection. …”
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49867
Parental Evaluation of a Responsive Parenting Program for Infants with Hearing Loss
Published 2025-01-01“…Their infants (<i>N</i> = 45) had moderate to complete hearing loss, they were aged 2–20 months, and 40% of them had an additional disease, disorder, and/or developmental delay. …”
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49868
Concept, features and types of corruption
Published 2022-03-01“…On a territorial basis, a distinction should be made between domestic (national) and transnational corruption, depending on the form of corruption - bribery, fraud, extortion, embezzlement (misappropriation) of public funds, clientelism, lobbying, favoritism, nepotism, state capture. In addition to these types of corruption, based on the definition of this legal phenomenon, which gives the legislator in the Law of Ukraine “On Prevention of Corruption”, depending on the form of corruption, the following types should be distinguished: acceptance of illegal gain; acceptance of a promise / proposal of illegal benefit. …”
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49869
Abrasion resistant characteristics of UHPC based on high-speed underwater method: Efficiency, process, evaluation, and mechanisms
Published 2025-01-01“…The wear characteristics of UHPC under high-speed water flow conditions were investigated using a 3D visualization quantitative method. Additionally, the abrasion mechanism of UHPC was analyzed using nanoindentation testing, SEM, and MIP techniques. …”
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49870
Development and Evaluation of selective nitroxanthone Derivatives: A promising compound for Targeting MCF-7 breast cancer cells
Published 2025-01-01“…The half-maximal inhibitory concentration (IC50) of compound 1 was 7.00 ± 0.00 µM for MCF-7 cells, compared to 250.00 ± 70.71 µM for HaCaT and 800.00 ± 0.00 µM for RAW 264.7 cells, yielding selectivity indices (SI) of 35.71 and 114.29, respectively. Additionally, compound 1 exhibited mortality concentrations of 1736.58 µM and 3660.35 µM for zebrafish and brine shrimp embryos, with SI values of 522.91 and 248.08, respectively. …”
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49871
Identification of depressive symptoms in adolescents using machine learning combining childhood and adolescence features
Published 2025-01-01“…The performance of each model was evaluated using a test set, and SHapley Additive exPlanations (SHAP) were utilized to interpret the models’ prediction results. …”
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49872
A prospective model of the potential clinical and economic impact of cervical cancer screening supported by a mobile phone app.
Published 2025-01-01“…<h4>Results</h4>In a simulated cohort of women using the app-based intervention compared to conventional care, with 10,000 women in each arm, use of the app is projected to increase healthcare costs by $12.53 per enrolled woman during the trial period and to detect and treat an additional 247 women-229 with precancerous cervical lesions and 18 with cervical cancer. …”
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49873
Design of low-carbon planning model for vehicle path based on adaptive multi-strategy ant colony optimization algorithm
Published 2025-01-01“…This includes various vehicle types, such as electric and autonomous vehicles, each with specific needs. Additionally, varying speeds and operational requirements further complicate the process, demanding more sophisticated planning solutions. …”
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49874
INFORMACINIS GENOMAS, INDIVIDO IR POPULIACIJOS GENOMAI
Published 2002-01-01“…Information genome increases by addition of new information necessary for individual and population under impact of selection. …”
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49875
CGV-Net: Tunnel Lining Crack Segmentation Method Based on Graph Convolution Guided Transformer
Published 2025-01-01“…This approach effectively addresses the challenge of modeling contextual information in crack feature extraction. Additionally, the Detailed-Macro Feature Fusion (DMFF) module enables multi-scale feature integration by combining detailed and coarse-grained features, mitigating the significant feature loss encountered during the encoding and decoding stages, and further improving segmentation precision. …”
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49876
ENHANCING PRODUCTION EFFICIENCY IN A HOME-BASED TEMPE CHIPS INDUSTRY
Published 2024-12-01“…The impact of implementingproduction management on the development of this home industry is increasingprofits, increasing orders, achievingproduction targets thatcan meetmarket needs, aswell as the addition of networksthat work together with the Berkah Jaya Tempe Chips Home Industry. …”
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49877
Social isolation in the young and middle-aged patients with stroke: role of social support, family resilience and hope
Published 2025-02-01“…In the mediating effects model, social support could influence social isolation directly (95% CI -0.250, -0.061) or indirectly through family resilience (95% CI -0.136, -0.062) or patient hope level (95% CI -0.078, -0.017). In addition, Family resilience and hope had a significant chain mediating effect between social support and social isolation (95% CI -0.029, -0.006).ConclusionsSocial support can have both direct and indirect effects on social isolation through the mediating factors of family resilience and hope. …”
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49878
Can urban compactness improve ecosystem services: Evidence from Chinese urban agglomerations
Published 2025-01-01“…The results of the spatial regression analysis indicated that there was a negative association between urban compactness and ESs in both 2010 and 2020. Additionally, the negative impact of urban compactness on HQ increased, while the effect on CS diminished. …”
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49879
Pharmacological Inhibition of Glutaminase 1 Normalized the Metabolic State and CD4+ T Cell Response in Sjogren’s Syndrome
Published 2022-01-01“…Inhibiting Gls1 with BPTES significantly abolished the proliferation rate, as indicated by EdU, CFSE, and Western blot analyses. Additionally, BPTES downregulated the extracellular acidification rate (ECAR) and oxygen consumption rate (OCR) values of activated CD4+ T cells from SS mice. …”
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49880
Immuno-Inflammatory Characteristics in Low Severity COVID-19 Patients with Digestive Symptoms
Published 2020-01-01“…Patients with digestive symptoms were more likely to have slightly higher and later peak values of inflammatory cytokines during the subsequent course of disease (P<0.05). In addition, a significant correlation between IL-2 and TNF level was found in the first group which included patients with digestive symptoms only (P<0.05). …”
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