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49761
نحو برنامج تدریبى مقترح لتدریب طلاب قسم المکتبات والمعلومات بکلیة الآداب جامعة الاسکندریة فى مقرر التدریب العملى...
Published 2020-01-01“…Thereis no gap between the theoretical study and the actual reality, with the need tohold meetings between the professor of material and students before the trainingperiod, where the clarification of the training plan and explain everything relatedto the practical training program, in addition to coordination with the large anddiverse libraries for the training of students during the summer period, And tofocus on teaching the technological materials for students in a practical way andbring them all new in the field of specialization.The study also showed that the percentage of male students in the librarydepartment reached 2.6%, while the proportion of females reached 97.4%, whichindicates that there is an unclear reason for the reluctance of male students tojoin the department, and 63.3% of students said that the duration of training is insufficient, as explained 60% of the students were satisfied with the practicaltraining program. …”
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49762
Risk factors for postoperative mortality with intra-aortic balloon counterpulsation in the early period after coronary artery bypass surgery in elderly and geriatric patients
Published 2019-06-01“…During the course of the study, 320 CABG procedures with cardiopulmonary bypass (CPB) were performed, among them 13 (4.06 %) patients required weaning from CPB by using intra-aortic balloon counterpulsation, with one patient additionally requiring the use of extracorporeal membrane oxygenation. …”
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49763
The impact of export market orientation on SME market performance: Exploring the moderating effect of government policy and the mediating effect of information access
Published 2025-01-01“…The findings demonstrate that export market orientation significantly boosts SME market performance (path coefficient = 0.512, p < 0.001), highlighting its critical role in fostering customer-oriented practices and adaptive marketing strategies. Additionally, export market orientation positively influenced information access (path coefficient = 0.359, p < 0.001), facilitating timely market insights that support decision-making. …”
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49764
Augmented virtuality technology in education: taxonomy of augmented virtuality types
Published 2024-12-01“…Various approaches to the augmented virtuality implementation by its addition with real objects are identified. Methodology. …”
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49765
A multi-strain human skin microbiome model provides a testbed for disease modeling
Published 2025-02-01“…A remarkable feature of this model is the persistence of Cutibacterium acnes in an aerobic tissue culture environment, since C. acnes growth is typically demonstrated under anaerobic conditions, suggesting that the skin tissue model is conducive to more natural growth states of native skin strains. The addition of cytokines representative of atopic dermatitis elicited a marked decrease in tissue barrier by day 7 compared to healthy controls, irrespective of the microbiome presence. …”
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49766
The efficacy of chelated micronutrient fertilisers in tomato cultivation
Published 2024-12-01“…The practical significance of this study lies in identifying the effects of foliar fertilisation on tomato yield in protected soil conditions. Additionally, the study established optimal and scientifically justified rates and application timings for complex fertilisers with chelated micronutrients. …”
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49767
Quantum chemical study of molecular properties of small branched-chain amino acids in water
Published 2025-01-01“…Calculated molecular descriptors involve dipole moment, quadrupole moment, dipole polarizability, energy of zero-point vibration and total entropic term which enter the standard Gibbs energy. In addition, a set of collective electronic and thermodynamic properties associated with redox process were evaluated: ionization energy, electron affinity, chemical hardness, molecular electronegativity, electrophilicity index, absolute oxidation and reduction potentials. …”
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49768
NT5E (CD73) as a prognostic biomarker and therapeutic target associated with immune infiltration in lung adenocarcinoma
Published 2025-02-01“…A strong positive correlation was observed between NT5E expression and the presence of immune cells, including dendritic cells, macrophages, and CD4+ T cells, as well as the expression of various immune cell markers, suggesting that NT5E may influence the prognosis of LUAD patients by regulating immune cell infiltration. Additionally, drug sensitivity analysis highlights the potential of selumetinib and PD318088, both MEK1/2 inhibitors, to target NT5E in LUAD treatment, suggesting their use as single agents or in combination with other therapies. …”
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49769
In silico methods for immunogenicity risk assessment and human homology screening for therapeutic antibodies
Published 2024-12-01“…Although this perspective discusses the in-silico immunogenicity risk assessment for monoclonal antibodies, bi-specifics, multi-specifics, and antibody-drug conjugates, the analysis of additional therapeutic modalities such as enzyme replacement proteins, blood factor proteins, CAR-T, gene therapy products, and peptide drugs is also made available on the ISPRI platform.…”
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49770
Dissecting macrophage heterogeneity and kaempferol in lung adenocarcinoma: a single-cell transcriptomic approach and network pharmacology
Published 2025-01-01“…Tumor-associated macrophages (TAMs) within the TME promote tumorigenesis and evasion of immune surveillance, though their heterogeneity poses challenges in understanding their roles and therapeutic targeting. Additionally, traditional Chinese medicine (TCM) offers potential anti-cancer agents that could modulate the immune landscape. …”
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49771
The effect of β-carotene supplementation above requirement on the production and reproduction performance of female sheep and goats - A mini review
Published 2024-05-01“…However, the supplementation of β-carotene above the requirements seems to not affect the production and reproduction parameters such as body weight, milk production, estrus parameters, conception rate, pregnancy rate, and litter size. …”
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49772
YTHDF1 Regulates RELA m6A Modification and Activates the NF‐Kappa B Signaling Pathway to Promote the Mechanism of Gastric Cancer
Published 2025-01-01“…YTHDF1 inhibits apoptosis while promoting the migration and proliferation of GC. Additionally, it stimulates the NF‐κB pathway and controls the translation of RELA.…”
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49773
Research on the Relationship between Dynamic Message Sign Control Strategies and Driving Safety in Freeway Work Zones
Published 2018-01-01“…The first occurrence of a decision sign that contains lane change content is key to the driver’s decision; in addition, the position of signage with such information should gradually be moved closer to work zones with increasing traffic flow.…”
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49774
Is preoperative imaging of sentinel lymph node in breast cancer necessary? A retrospective case control study
Published 2025-02-01“…Lymphoscintigraphy detected SLN in 407 of 428 (95.09 %) patients in group 2. Due to the additional SLN imaging in group 2, the time between radiotracer injection and start of surgery was significantly prolonged (p < 0.001). …”
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49775
IHSCR: Energy-efficient clustering and routing for wireless sensor networks based on harmony search algorithm
Published 2017-11-01“…Then, a new energy-efficient clustering algorithm is designed based on several improvements made to harmony search algorithm: (1) a discrete encoding scheme of a harmony for clustering is proposed; (2) a roulette wheel selection method is designed to choose a gateway for a regular sensor node to join, which is employed by two steps (i.e. initialization of harmony and improvisation of a new harmony); (3) the dynamically changed harmony memory considering rate is designed for improvisation of a new harmony; (4) a local search scheme is proposed to improve the best harmony within the harmony memory in iterations. In addition, the improved harmony search based energy-efficient routing algorithm that we proposed previously is employed to balance the energy consumption of gateways in the routing phase. …”
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49776
Appropriate Blood Pressure in Cerebral Aneurysm Clipping for Prevention of Delayed Ischemic Neurologic Deficits
Published 2020-01-01“…To prevent DNID, we recommend that optimal blood pressure should not be lower than 95 for SBP, 50 for DBP, and 61.7 mmHg for MAP. Additionally, we suggest that Δ SBP, Δ DBP, and Δ MAP should be less than 36, 27, and 32 mmHg, respectively.…”
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49777
Intranasal Immunization with DNA Vaccine HA-CCL19/Polyethylenimine/Chitosan Composite Provides Immune Protection Against H7N9 Infection
Published 2024-12-01“…Results: Our results revealed that the CCL19 molecular adjuvant exerts a substantial immunomodulatory enhancement effect on the H7N9-HA DNA vaccine, inducing more pronounced cellular and humoral immunity. Additionally, our results indicated that the composite formed by the HA-CCL19 DNA in combination with PEI and CS effectively activates local mucosal immunity as well as systemic humoral and cellular immunity, offering 100% protection against lethal doses of homologous virus challenges. …”
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49778
Quality of Life of Palestinian Patients on Hemodialysis: Cross-Sectional Observational Study
Published 2023-01-01“…There was a positive correlation between MCS and KDCS (r = 0.634, P-value <0.001), PCS and KDCS (r = 0.569, P-value <0.001), as well as MCS and PCS (r = 0.680, P-value <0.001). …”
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49779
Vagal nerve stimulation dynamically alters anxiety-like behavior in rats
Published 2025-03-01“…Anxiety-like behavior was assessed using the elevated plus maze, open field test, and novelty-suppressed feeding test. Additionally, a place preference assay determined whether VNS is rewarding or aversive. …”
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49780
An Efficient Herbal Approach for Treating Fungal Infection in Cervical Cancer Patients by Developing and Optimizing a Vaginal Suppository
Published 2021-01-01“…Combinations of PEG 1500 (10%–40%), PEG 6000 (40%–60%), and Poloxamer 407 (5%–30%) were entered as factors, and the responses evaluated were hardness, deformation time, and % drug release. In addition, the formulation was also evaluated for visual examination, weight variation, pH determination, drug content, hardness test, disintegration time, melting zone, deformation time, in vitro drug release, antifungal activity, and stability tests. …”
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