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49641
Smartphone postural sway and pronator drift tests as measures of neurological disability
Published 2025-02-01“…In conclusion, a simple 1-min postural sway test accurately measures body oscillations that increase with natural aging and differentiates them from abnormally increased body oscillations in people with neurological disabilities.…”
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49642
Polysaccharide Fraction Isolated from <i>Saccharina japonica</i> Exhibits Anti-Cancer Effects Through Immunostimulating Activities
Published 2025-01-01“…Consequently, this finding suggested that SJP from <i>S. japonica</i> possesses remarkable anti-cancer effects through the activation of various immunocytes. In addition, this finding indicates that the potent biological activity of SJP may be attributed to fucoidan.…”
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49643
High-density lipoprotein cholesterol as a prognostic marker for 90-day transplant-free mortality in hepatitis B virus-related acute-on-chronic liver failure
Published 2025-01-01“…The prognostic value of HDL-C (AUC at day 90: 0.732) was comparable to the model for end-stage liver disease score of 0.729. Additionally, HDL-C levels were inversely correlated with interleukin (IL)-4, IL-6, and tumor necrosis factor-α (all P<0.05). …”
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49644
Characteristics and Development Mechanisms of Northeast Cold Vortices
Published 2021-01-01“…Apart from the jets and circulation, the lower central potential height combined with the obvious cold-core and stronger ascending motions favor the NCV’s development. In addition, the dry intrusion has a strong promotion due to the stronger lower-level cold advection and downward intrusion of high potential vorticity. …”
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49645
INTERACTIVE WEB 2.0 TOOLS IN CONTENT AND LANGUAGE INTEGRATED LEARNING
Published 2017-02-01“…The authors have analyzed the experience of using CLIL in European universities and made the conclusion that the most challenging part of implementation the CLIL methodology is the development of bilingual educational materials. In addition, students and teachers working in a CLIL setting face with a lack of suitable learning materials in the target language for subjects. …”
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49646
Evaluation of Sharia-based Sustainability Reporting Framework Influenced by the Emergence of Metaverse Axes in Accounting
Published 2023-03-01“…By promoting jurisprudential values and Shariah standards, Islamic societies are always seeking to strengthen the level of adherence to morality, and this issue has caused many countries to consider Islamic rules in addition to international standards and laws to achieve greater legitimacy. …”
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49647
Cohort study evaluating pressure ulcer management in clinical practice in the UK following initial presentation in the community: costs and outcomes
Published 2018-07-01“…The mean NHS cost of wound care over 12 months ranged from £1400 for a category 1 ulcer to >£8500 for the other categories of ulcer. Additionally, the cost of managing an unhealed ulcer was 2.4 times more than that of managing a healed ulcer (mean of £5140 vs £12 300 per ulcer).Conclusion This study provides important insights into a number of aspects of PU management in clinical practice in the community that have been difficult to ascertain from other studies, and provides the best estimate available of NHS resource use and costs with which to inform policy and budgetary decisions.…”
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49648
Oncogenic RIT1 mutations confer ferroptosis vulnerability in lung adenocarcinoma
Published 2025-02-01“…Transcriptomic profiling indicated that oncogenic RIT1 mutant expression influenced common tumorigenic RAS/MAPK, PI3K/AKT, and E2F1 pathways, in addition to altered NFE2L2 target expression. Importantly, RIT1 mutants markedly sensitized cells to ferroptosis induction, and RIT1 knockdown suppressed ferroptotic cell death. …”
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49649
Integrating univariate and multivariate stability indices for breeding clime-resilient barley cultivars
Published 2025-01-01“…Spearman’s correlation analysis indicated significant positive correlations (P < 0.01) between GY and various stability parameters such as linear regression coefficients (bi), Perkins and Jinks’s stability parameters (Bi), environmental variance (Sxi 2) and Tai’s environmental effects (αi), among others, as univariate stability measures. Additionally, nonparametric measures such as Nassar and Huhn’s (SI 6 and SI 3) and Thennarasu’s (NP I (3) and NP I (4)), TOP-rank stability and the yield stability index (YSI), showed significant correlations with GY. …”
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49650
Unraveling the Beneficial Role of Resveratrol in Fructose-Induced Non-Alcoholic Steatohepatitis with a Focus on the AMPK/Nrf2 Signaling Axis
Published 2025-01-01“…<i>Materials and Methods</i>: Sixty male albino rats were allocated to three groups: group I, the normal control group; group II, the fructose-enriched diet group (FED), which was fed a 70% fructose diet for six weeks to induce NASH; and group III, the resveratrol–FED group (RES + FED), which was given the same FED diet plus an oral dose of 70 mg/kg resveratrol (RES) every day for an additional six weeks. We performed histological evaluations and assessed blood lipids and liver enzymes to study resveratrol’s impact on NASH. …”
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49651
Long-chain chlorinated paraffins (LCCPs) exposure induces apoptosis in primary chicken embryo hepatocytes through oxidative stress
Published 2025-01-01“…Our findings indicate that the proliferation capacity of primary chicken embryo hepatocytes exposed to LCCPs at concentrations of 1, 10, and 100 μg/L was significantly diminished, with an observed arrest in the G0/G1 phase and a notable reduction in the proportion of cells in the G2/M phase. Additionally, we observed that LCCPs exposure markedly decreased the autophagy levels in primary chicken embryo hepatocytes while significantly increase the levels of apoptosis. …”
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49652
ERCP-Related Adverse Events in Primary Sclerosing Cholangitis: A Systematic Review and Meta-Analysis
Published 2022-01-01“…Additionally, accidental wire passage and biliary sphincterotomy increased the odds of PEP. …”
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49653
Giant Parotid Pleomorphic Adenoma with Atypical Histological Presentation and Long-Term Recurrence-Free Follow-Up after Surgery: A Case Report and Review of the Literature
Published 2020-01-01“…To the best of knowledge from indexed literature, giant parotid PA is rarely reported in Saudi Arabia. In addition to its rarity, this case is reported for its benign nature despite atypical histological presentation, successful surgical management without complications, and long-term recurrence-free follow-up. …”
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49654
CalciumZero: a toolbox for fluorescence calcium imaging on iPSC derived brain organoids
Published 2025-01-01“…It streamlines the entire analysis process, offering full automation with just one click after parameter optimization. In addition, it includes supplementary features to statistically evaluate the impact on disease etiology and the detection of drug candidate effects on calcium activities. …”
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49655
Effects of Different Solvents on the Total Phenol Content, Total Flavonoid Content, Antioxidant, and Antifungal Activities of Micromeria graeca L. from Middle Atlas of Morocco
Published 2024-01-01“…In addition, the strongest antioxidant activity measured by DPPH and FRAP assays was established in water extract with IC50 values of 0.33 ± 0.23 and 0.23 ± 0.12 mg/mL, respectively, while the methanol extract showed the best antioxidant activity as measured by TAC with an IC50 of 483 ± 17.6 mg GAEq/g dry weight plant. …”
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49656
The production process of spring wheat plants in the system of biological agriculture
Published 2025-01-01“…Analyzing photosynthetic processes in a plant makes it possible to opine on the rate of its growth and development. In addition to classical physiological techniques, an interest is currently growing in spectrometry, which provides a realtime opportunity, based in the values of vegetation indices, to find out whether a plant is under stress or not.Materials and methods. …”
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49657
Phenotypic Definition of the Progenitor Cells with Erythroid Differentiation Potential Present in Human Adult Blood
Published 2011-01-01“…These results confirm that the majority of HPC in AB express CD34 but identify additional CD34neg populations with erythroid differentiation potential which, based on differences in fold-increase and maturation times, may represent a hierarchy of HPC present in AB.…”
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49658
Rooftop Photovoltaic for Residential Electricity Self-Sufficiency: Assessing Potential Benefits in Major Japanese Cities
Published 2024-12-01“…These findings reveal that while RTPV has substantial potential to improve residential electricity self-sufficiency, additional efforts are necessary to accelerate adoption. …”
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49659
Development of Predictive Models for Progression from Diabetic Kidney Disease to End-Stage Renal Disease in Type 2 Diabetes Mellitus: A Retrospective Cohort Study
Published 2025-02-01“…The developed models offer improved accuracy over existing methods by incorporating renal pathology and novel inflammatory indices, making them more applicable in clinical settings.Conclusion: The predictive model proved to be effective in assessing the progression of DKD to ESRD. Additionally, the combined model of KFRE, IFTA, SII, and BMI demonstrates high predictive performance. …”
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49660
New epigenome players in the regulation of PCSK9-H3K4me3 and H3K9ac alterations by statin in hypercholesterolemia
Published 2025-01-01“…We observed that atorvastatin (ATS) increases the fold enrichment of H3K4me3 at the promoter of PCSK9 by elevating the expression of the SET1/COMPASS family of proteins like SET1b and MLL1 in HepG2. In addition, ATS also acetylates H3K9 by increasing the expression of acetyltransferases like CBP and PCAF. …”
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