The OXT rs6133010 variant modulates susceptibility to psychiatric symptoms during withdrawal in patients with alcohol dependence by Guanghui Shen, Wei Wang, Yuyu Wu, Xinguang Luo, Kexin Wang, Yu-Hsin Chen, Yimin Kang, Yanlong Liu, Fan Wang, Li Chen

“…These findings emphasize considering environmental factors when studying and utilizing oxytocin therapeutically. Additionally, OXT may not directly act as an anxiolytic but instead regulates anxiety by modulating hostility.…”
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Persistence and emergence of X4 virus in HIV infection by Ariel D. Weinberger, Alan S. Perelson

“…Approximately 50% of late-stage HIV patients develop CXCR4-tropic (X4) virus in addition to CCR5-tropic (R5) virus. X4 emergence occurs with a sharp decline in CD4+ T cell counts and accelerated time to AIDS. …”
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Explainable Machine Learning for Efficient Diabetes Prediction Using Hyperparameter Tuning, SHAP Analysis, Partial Dependency, and LIME by Md. Manowarul Islam, Habibur Rahman Rifat, Md. Shamim Bin Shahid, Arnisha Akhter, Md Ashraf Uddin, Khandaker Mohammad Mohi Uddin

“…What is more, to improve the comprehensibility of the proposed model, a variety of explainability methodologies such as SHapley Additive Explanations (SHAP), Partial Dependency, and Local Interpretable Model‐agnostic Explanations (LIME) have been implemented which are not often noticed in the previous works. …”
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Harmonizing the past: EEG-based brain network unveil modality-specific mechanisms of nostalgia by Hu Shuxiang, Hu Shuxiang, Liu Ying, Liu Ying, Yue Qizong, Yue Qizong, Zhao Huan, Zhao Huan, Zheng Maoping, Zheng Maoping

“…At the neural level, nostalgic stimuli enhanced the connection strength, global and local efficiency, and diminished eigenpath length of brain networks in the alpha and gamma bands. Additionally, nostalgia through the auditory channel induced higher activity intensity in the theta and gamma bands and increased brainwave amplitudes in the alpha bands. …”
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Single-cell transcriptomics identify a novel macrophage population associated with bone invasion in pituitary neuroendocrine tumors by Xinzhi Wu, Xueshuai Han, Haibo Zhu, Mingxuan Li, Lei Gong, Sicheng Jing, Weiyan Xie, Zhaoqi Liu, Chuzhong Li, Yazhuo Zhang

“…TNF-α+ TAMs, in turn, communicate with CD14 + monocytes to promote their differentiation into osteoclasts and leading to bone invasion. In addition, we defined a gene signature for TNF-α+ TAM to guide the clinical prognosis prediction of BI PitNETs. …”
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Association between obstructive sleep apnea hypopnea syndrome and arteriosclerosis in patients with type 2 diabetes mellitus: mediating effect of blood pressure by Xinshui Wang, Xiaolin Huang, Yuexian Xing, Xiaohong Jiang, Fei Hua

“…The relationship between the apnea-hypopnea index (AHI) and arteriosclerosis was analyzed using univariable and multivariable logistic regression models, while a generalized additive model (GAM) was applied for curve fitting. …”
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Comparison of the Applicability of Two Reanalysis Products in Estimating Tall Tower Wind Based on Multiple Linear Regression and Artificial Neural Network in South China by Xiangxiang Li, Xiaochen Qin, Jun Yang, Weiming Xu

“…For the wind direction, the two reanalysis datasets did not display distinct differences. Additionally, the misalignment of the wind direction between the reanalysis products and the TTOs was higher for the secondary predominant wind direction (SPWD) than for the predominant wind direction (PWD). …”
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Internet use and adolescent development in rural China: A scoping review protocol of research landscape and gaps. by Linxiao Zhang

“…It will advance the research agenda on this issue conceptually, theoretically, and empirically. In addition, it can provide contextual implications for designing prevention and intervention programs.…”
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Structural and functional changes of Post-Stroke Depression: A multimodal magnetic resonance imaging study by Qiuhong Lu, Shunzu Lu, Xue Wang, Yanlan Huang, Jie Liu, Zhijian Liang

“…This study investigated changes in gray matter volume (GMV), white matter microstructure, and spontaneous brain activity in post-stroke depression (PSD) using multiple MRI techniques, including neurite orientation dispersion and density imaging (NODDI). Changes in GMV, neurite density index (NDI), orientation dispersion index (ODI), fraction of isotropic water (ISO), diffusion tensor imaging (DTI) parameters, and the amplitude of frequency fluctuations (ALFF) were assessed between PSD (n = 20), post-stroke without depression (n = 20), and normal control (n = 20) groups. …”
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Labour Education and Vocational Training in Germany: A Brief Historical Review by E. Yu. Esenina, L. N. Kurteeva, S. A. Osadcheva, A. I. Satdykov, H Kress

“…The leading method was a comparative retrospective analysis, which allowed the authors to compare various scientific resources. In addition, the approaches of goal-setting and formalisation of expected results were applied. …”
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Production of novel theranostic nano-vector based on superparamagnetic iron oxide nanoparticles/miR-497 targeting colorectal cancer by Asmaa M. Elfiky, May M. Eid, May El-Manawaty, Zeinab A. Elshahid, Elham Mohamed Youssef, Khaled Mahmoud

“…This study aims to create new super paramagnetic iron oxide nano-carrier (SPION) that can effectively transport miRNA to specific CRC cell lines. In addition, evaluate the efficiency of this nano-formulation as a therapeutic candidate for CRC. …”
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Early Information About Bio-physical Quality of Seaweed Culture (Eucheuma cottonii) in Waworada Bay, Bima Regency by M. Sirajuddin

“…PCA analysis shows that the main parameters of growth seaweed culture was light penetration, water current, water deepness, pest, salinity, nitrate and Pb. As additional parameters were temperature, COD, DO, Phosphate, and pH. …”
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Analysis of the Concentration of Heavy Metals in Khat Grown in Meru County and the Assessment of Their Associated Health Risks by Albert M. Oyugi, Joshua K. Kibet, John O. Adongo

“…The mean heavy metal concentrations (mg/kg) in dry khat samples of six toxic heavy metals were Cd (7.81 ± 1.56), Cr (15.98 ± 2.22), Cu (15.81 ± 2.84), Fe (97.35 ± 32.67), Ni (0.37 ± 0.02), and Pb (32.36 ± 9.95). …”
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Concurrent Viewing of H&E and Multiplex Immunohistochemistry in Clinical Specimens by Larry E. Morrison, Tania M. Larrinaga, Brian D. Kelly, Mark R. Lefever, Rachel C. Beck, Daniel R. Bauer

“…<b>Results:</b> Application is made to several clinically relevant specimens, including breast cancer (HER2, ER, and PR), prostate cancer (PSMA, P504S, basal cell, and CD8), Hodgkin’s lymphoma (CD15 and CD30), and melanoma (LAG3). Additionally, invisible chromogenic IHC was combined with conventional DAB IHC to present a multiplex IHC assay with unobscured DAB staining, suitable for visual interrogation. …”
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Impact of fluoxetine exposure on Lymnaea stagnalis and its developing eggs: integrating untargeted lipidomics, targeted metabolomics, and classical risk assessment by Diana Ilyaskina, Yumi Nakadera, Yumi Nakadera, Marja H. Lamoree, Joris M. Koene, Pim E. G. Leonards

“…In the albumen gland, we detected a decrease of key lipid classes, including sphingomyelins and fatty acids, which can be linked with impaired egg quality. Additionally, a decrease in histamine in both the albumen gland and eggs suggested further disruption of egg development, potentially affecting metamorphosis success. …”
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Rutaecarpine alleviates hepatic ischemia‒reperfusion injury in liver transplantation by inhibiting inflammatory response and oxidative stress by Yan Liu, Yan Liu, Feng Qi, Lun-Jian Xiang, Zhu-Jun Yi, Sheng-Wei Li

“…The target was further validated by in silico, in vivo and in vitro experiments.ResultsRut significantly alleviated liver dysfunction, pathological injury, and apoptosis and improved the survival rate of the rats subjected to LT. In addition, Rut significantly inhibited inflammatory response and oxidative stress. …”
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Identification of Pyrrolizidine Alkaloids in Senecio Plants by Liquid Chromatography-Mass Spectrometry by An-Jing Lu, Yan-Liu Lu, Dao-Peng Tan, Lin Qin, Hua Ling, Chang-Hong Wang, Yu-Qi He

“…Finally, we classified these plants into five categories based on PAs which were identified in the present study; the result corresponded with the classification by morphology. In addition, we have found some constituents that have odd molecular weight number only in Senecio species but not in Ligularia species; the detailed structures of these non-PAs constituents need penetrating study. …”
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Artificial intelligence-based approaches for multi-station modelling of dissolve oxygen in river by G. Elkiran, V. Nourani, S.I. Abba, J. Abdullahi

“…The simulated results of dissolved oxygen at three stations indicated that, multi-linear regression is found not to be efficient for predicting dissolved oxygen. In addition, both artificial intelligence models were found to be more capable and satisfactory for the prediction. …”
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Active learning in undergraduate classroom dental education- a scoping review. by Arnaldo Perez, Jacqueline Green, Mohammad Moharrami, Silvia Gianoni-Capenakas, Maryam Kebbe, Seema Ganatra, Geoff Ball, Nazlee Sharmin

“…Only 4 studies (4.3%) reported faculty data in addition to student data. Flipped learning, group discussion, problem-based learning, and team-based learning were the active learning strategies most frequently evaluated (≥6 studies). …”
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TRANSFORMATION OF SOCIAL AND HUMANITARIAN SPHERE OF WORLD POLITICS: CHALLENGES FOR RUSSIA by M. M. Lebedeva, L. R. Rustamova

“…In turn, the disintegration of the bipolar system of interstate relations did not lead to the disappearance of the ideological factor, and the social and humanitarian issues became especially important in the interstate interaction. …”
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