Investigating the impact of dioxins, furans, and coplanar polychlorinated biphenyls on mortality, inflammatory states, and chronic diseases: An integrative epidemiological analysis by Jiaxing Tan, Ying Gao, Yuanlin Xia, Peiyan Sun, Wei Qin

“…Moreover, these pollutants were linked to a higher incidence of chronic diseases, including hematological disorders, chronic kidney disease, hypertension, and diabetes (p < 0.05). Additionally, a robust correlation was observed between serum C-reactive protein (CRP) and neutrophil-to-lymphocyte ratio (NLR) concentrations and these substances, revealing their proinflammatory effects at specific concentrations. …”
Get full text

Muon spectroscopy of a 12-phosphatetraphene with extremely efficient radical trapping properties by Shigekazu Ito, Kohei Yasuda, Keisuke Ishihara, Victoria L. Karner, Kenji M. Kojima, Iain McKenzie

“…This muoniated radical was produced by the diffusion-controlled regioselective addition of muonium (Mu = [µ+e–]) to the sp2-hybridized phosphorus atom. …”
Get full text

Was Aristotle right about moral decision-making? Building a new empirical model of practical wisdom. by Shane McLoughlin, Stephen Thoma, Kristján Kristjánsson

“…Study 1b confirmed these findings in two additional nationally representative samples from the UK and the US. …”
Get full text

Can Digital Rectal Examination Identify the Subtype of Dyssynergic Disorders as Well as High Resolution Anorectal Manometry? by Philippe Onana Ndong, Karine Baumstarck, Véronique Vitton

“…Conclusion DRE demonstrates satisfactory performance in diagnosing the four subtypes of DD. Enhanced training in DRE, emphasizing functional information, has the potential to reduce reliance on additional tests, thereby mitigating economic and organizational impacts.…”
Get full text

Synergism of d-limonene and temozolomide on migratory and apoptotic behaviors of human glioblastoma cell lines by Megha Gautam, Reema Gabrani

“…Furthermore, the DL+TMZ combination induced apoptosis by upregulating the expression of Bax, and Caspase (CASP)-3, while reducing the expression of the Bcl-2 gene in GBM cells. In addition, the combined treatment of DL+TMZ significantly decreased the expression of matrix metalloproteinase (MMP)-2 and MMP-9, expression, indicating inhibition of cell migration in GBM cells. …”
Get full text

The effect of transcranial random noise stimulation on the movement time and components of noise, co-variation, and tolerance in a perceptual-motor task by Fatemeh Salehi, Mohammadreza Doustan, Esmaeel Saemi

“…Statistical analyses showed that training with tRNS has a significant effect on noise cost, co-variation, and movement tolerance (p ≤ 0.05). In addition, tRNS improved the function of the sensorimotor wave (p ≤ 0.05). …”
Get full text

Incidence of prostate adenocarcinoma in transurethral resection of the prostate patients by Yahia Ghazwani, Abdullah Alhaider, Rakan Aldharab, Faisal Aldumiaikhi, Nasser Albogami, Abdulaziz Alathel, Ali Alothman, Raghib Abusaris, Mosaad Alshahwan, Fahad Alhamad, Ziyad Aljaafri, Khalid Alduraibi

“…IPCa cases were identified through the pathology reports of the prostatic chips. In addition, cancer stage, Gleason score, treatment choices, and outcomes were documented for IPCa cases. …”
Get full text

Assessing food safety and hygiene practices in old age homes in Mangaung and Lejweleputswa regions, free state by Tshegofatso Nhabe, Ntsoaki J. Malebo

“…Data were collected using questionnaires (N = 80) to evaluate food handlers’ knowledge, attitudes, and behaviors. Additionally, a food safety checklist was used to assess compliance with hygiene and safety standards.ResultsThe study identified gaps in food safety practices and regulatory compliance. …”
Get full text

Gender-associated features in diabetic kidney disease by S.S. Safarova

“…Additionally, men were more likely to have adverse risk factors, including dyslipidemia, lower high-density lipoprotein cholesterol, and glomerular filtration rate, which are factors involved in the mechanisms of DKD. …”
Get full text

International Burden of Chronic Kidney Disease and Secondary Hyperparathyroidism: A Systematic Review of the Literature and Available Data by Elizabeth Hedgeman, Loren Lipworth, Kimberly Lowe, Rajiv Saran, Thy Do, Jon Fryzek

“…International societies of nephrology were contacted to seek additional information regarding available data. Estimates were abstracted from 35 sources reporting estimates of CKD in 25 countries. …”
Get full text

Neuroprotective Effects of Myrtle Berry By-Product Extracts on 6-OHDA-Induced Cytotoxicity in PC12 Cells by Debora Dessì, Giacomo Fais, Paolo Follesa, Giorgia Sarais

“…Using PC12 cells exposed to 6-hydroxydopamine (6-OHDA), we assessed cell viability via MTT assay and measured reactive oxygen species (ROS) production using DCFDA fluorescence. Additionally, we analyzed the expression of genes linked to oxidative stress and neuronal function, including AChE, PON2, Grin1, Gabrd, and c-fos, by RT-PCR. …”
Get full text

Theoretical Study of C2H5 + NCO Reaction: Mechanism and Kinetics by Nan-Nan Wu, Shun-li OuYang, Liang Li

“…The calculated results show that both the N and O atoms of the NCO radical can attack the C atom of C2H5 via a barrierless addition mechanism to form two energy-rich intermediates IM1 C2H5NCO (89.1 kcal/mol) and IM2 C2H5OCN (64.7 kcal/mol) on the singlet PES. …”
Get full text

Modulatory Action by the Serotonergic System: Behavior and Neurophysiology in Drosophila melanogaster by Zana R. Majeed, Esraa Abdeljaber, Robin Soveland, Kristin Cornwell, Aubrey Bankemper, Felicitas Koch, Robin L. Cooper

“…To determine which 5-HT receptor subtype modulates the evoked sensory-motor activity, pharmacological agents were used. In addition, the activity of 5-HT neurons was enhanced by expressing and activating TrpA1 channels or channelrhodopsin-2 while recording the evoked excitatory postsynaptic potentials (EPSPs) in muscle fibers. 5-HT2 receptor activation mediates a modulatory role in a sensory-motor circuit, and the activation of 5-HT neurons can suppress the neural circuit activity, while fluoxetine can significantly decrease the sensory-motor activity.…”
Get full text

Agreement on the termination of obligation by transferring indemnity: content and special features by V. V. Rasskazova

“…It has been emphasized that the function of the indemnity agreement is to record the parties’ agreement to terminate the principal obligation in this way, as well as explained the peculiarity of the indemnity agreement as a combination of the features of the law-establishing and law-terminating legal fact, since the agreement both gives rise to additional rights and obligations for the parties and serves to terminate the original obligation as a result of its execution i.e. transfer of the indemnity by the debtor to the creditor. …”
Get full text

Association between magnesium depletion score and prostate cancer by Hongyang Gong, Xiaomei Lin, Shaoqun Huang

“…After adjusting for all variables using multivariable logistic regression, each 1-unit increase in MDS was associated with a 26% higher prevalence of PCa (OR = 1.26, 95% CI: 1.05, 1.50). Additionally, compared to an MDS of 0, an MDS of 3 or higher was associated with a 3.04-fold increase in PCa prevalence (OR = 3.04, 95% CI: 1.53, 6.01). …”
Get full text

ISLAM AND NEO-MODERNISM IN INDONESIA: REVISITING NURCHOLISH MADJID AND ABDURRAHMAN WAHID’S THOUGHT ON CIVIL SOCIETY by Dito Alif Pratama

“…Adapting the concept of Barton (1997), both Madjid and Wahid are not only prominent public intellectuals but also can be considered intellectual ulama, scholars who combine the best of classical scholarship and intellectual leadership with modern secular and Islamic learning and participated alongside other public intellectuals in Indonesia's civil society forums. In addition, Greg Barton labels these personalities and characteristics of thought as Neo-Modernists or Neo-Modernist thinkers. …”
Get full text

Evaluation of efficacy of photodynamic disinfection against enterococcus faecalis and compare it with the effect of different endodontic irrigant activation techniques. by Amanda George Haskiyal, Dara Hamarashid Saeed

“…SEM results indicated that the FotoSan group (5.56±3.16) and Diode laser (5.56±3.57) had the lowest surviving colony mean number. Conclusion: As an additional method, photodynamic therapy may increase the disinfection capacity of traditional endodontic treatment against E. faecalis in the root canal. …”
Get full text

Incremental Cost Analysis of Training of Trainers and Helpers in Problem Management Plus (PM+) Using an Ensuring Quality in Psychological Support (EQUIP) Competency-based Approach... by Gloria A. Pedersen, Niko C. Gautam, Kriti Pudasaini, Nagendra P. Luitel, Michael W. Long, Alison Schafer, Brandon A. Kohrt

“…For PM+ trainers, a standard PM+ ToT costs NPR 63,800.06 (US$510.40), with additional training on EQUIP competency-based approaches and digital platform costing an incremental NPR 45,111.15 (US$360.89). …”
Get full text

Improved recommender system using Neural Network Collaborative Filtering (NNCF) for E-commerce cosmetic product by Subhan Subhan, Deny Lukman Syarif, Endah Widhihastuti, Senda Kartika Rakainsa, Muhammad Sam'an, Yahya Nur Ifriza

“…To validate the effectiveness of our proposed system, extensive experiments were conducted using real-world e-commerce cosmetic datasets "eCommerce Event History in Cosmetics Shop".   Additionally, we evaluate the system's performance using historical e-commerce event data in cosmetics stores, demonstrating the system's effectiveness with mean reciprocal ratings (MRR) and normalized discount cumulative gain (NDCG). …”
Get full text

Mechanistic relationship between obesity-induced inflammation triggering endothelial dysfunction and the initiation of atherosclerosis development by Richard L. Jayaraj, Elhadi H Aburawi

“…Endothelial dysfunction is the first step in the mechanisms underlying obesity-related complications, such as atherosclerosis, which is a major complication of obesity. A growing body of evidence suggests that obesity-related ED makes a significant contribution to the development of CVD and MD. …”
Get full text