Impact of visual presentation of atherosclerotic carotid plaque on cardiovascular risk profile using mHealth technologies by Greta Ullrich, Alexander Bäuerle, Lisa Maria Jahre, Katrin Paldán, Jana Rosemeyer, Chiara Kalaitzidis, Christos Rammos, Martin Teufel, Tienush Rassaf, Julia Lortz

“…The intervention group received the PreventiPlaque app during the 12-month study period in addition to standard care. The app contained daily tasks that promoted lifestyle modifications and adherence to prescribed medication. …”
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Nasal Adenocarcinoma in a Horse with Metastasis to Lung, Liver, and Bone and Review of Metastasis in Nine Horses with Sinonasal Tumors by Ashley Hanna, Susanne M. Stieger-Vanegas, Jerry R. Heidel, Melissa Esser, John Schlipf, Jacob Mecham

“…This case report describes the clinical and imaging findings of a horse with sinonasal neoplasia, which had metastasized to the lung, liver, and humerus. Additionally, the prevalence of sinonasal neoplasia and their incidence of distant metastasis among horses that presented to the Oregon State University Veterinary Teaching Hospital (OSU-VTH) were estimated. …”
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Application Strategies of Super-Enhancer RNA in Cardiovascular Diseases by Yi He, Yuwei Cai, Yanyan Cao, Yan Wang, Jing Wang, Hu Ding

“…The development of specific inhibitors or activators is expected to facilitate precise interventions for CVDs. In addition, the use of gene editing techniques to modify relevant eRNA introduces new possibilities for disease treatment. …”
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Weakened future surface warming in China due to national planned afforestation through biophysical feedback by Shuaifeng Song, Xiaodong Yan, Xuezhen Zhang, Zhibo Gao, Wenqiang Xie

“…The results show that afforestation induces a significant cooling effect over the period 2041–2060 under the SSP2-4.5 scenario, in particular in the cold season. The additional cooling effect offsets about 3.69% of the projected LST increase due to global warming and even overcompensates the LST increase in southwestern China. …”
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Pharmacogenomic screening identifies and repurposes leucovorin and dyclonine as pro-oligodendrogenic compounds in brain repair by Jean-Baptiste Huré, Louis Foucault, Litsa Maria Ghayad, Corentine Marie, Nicolas Vachoud, Lucas Baudouin, Rihab Azmani, Natalija Ivljanin, Alvaro Arevalo-Nuevo, Morgane Pigache, Lamia Bouslama-Oueghlani, Julie-Anne Chemelle, Marie-Aimée Dronne, Raphaël Terreux, Bassem Hassan, François Gueyffier, Olivier Raineteau, Carlos Parras

“…In an adult MS model of focal de/remyelination, they improve lesion repair by promoting OPC differentiation while preserving the OPC pool. Additionally, they shift microglia from a pro-inflammatory to a pro-regenerative profile and enhance myelin debris clearance. …”
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A thermodynamic bottleneck in the TCA cycle contributes to acetate overflow in Staphylococcus aureus by Nabia Shahreen, Jongsam Ahn, Adil Alsiyabi, Niaz Bahar Chowdhury, Dhananjay Shinde, Sujata S. Chaudhari, Kenneth W. Bayles, Vinai C. Thomas, Rajib Saha

“…This bottleneck reduces flux through the TCA cycle, making it more efficient for S. aureus to generate ATP via acetate overflow metabolism. Additionally, the protein allocation cost of maintaining ATP flux through the restricted TCA cycle is greater than that of acetate overflow metabolism. …”
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Muscle Satellite Cells: Exploring the Basic Biology to Rule Them by Camila F. Almeida, Stephanie A. Fernandes, Antonio F. Ribeiro Junior, Oswaldo Keith Okamoto, Mariz Vainzof

“…Satellite cells are maintained in a quiescent state and upon requirement are activated, proliferating, and fusing with other cells to form or repair myofibers. In addition, they are able to self-renew and replenish the stem pool. …”
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An Overview of Nanotechnology in Food Science: Preparative Methods, Practical Applications, and Safety by Hyunjong Yu, Jun-Young Park, Chang Woo Kwon, Sung-Chul Hong, Kyung-Min Park, Pahn-Shick Chang

“…Targeted delivery systems designed with nanoencapsulation can enhance bioavailability of bioactive compounds after oral administration. In addition, nanoencapsulation enables to control the release of flavors at the desired time and to protect the degradation of flavors during processing and storage. …”
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Clay Shoveler's Fracture: A Pain in the Neck by Marc Boutros, Maria R. Karam, Maria El Asmar, Emmanuelle Wakim, Labib Chebli, Pierre Maurice Doumit Bader Tarabay, Sami Roukoz

“…This fracture may occur as a consequence of a direct blow/trauma, a contraction of the shoulder muscles, and sudden extreme movements of the neck influenced by additional factors presented throughout the article. …”
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An Unusual Presentation of COVID-19 Associated Multisystem Inflammatory Syndrome in Adults (MIS-A) in a Pregnant Woman by Mohamed Rishard, Suren Perera, Kushan Jayasinghe, Amila Rubasinghe, Sanjaya Athapaththu, Malindu Edirisinghe, Prabhodana Ranaweera, Tushani Ranawaka, Athula Kaluarachchi, Priyankara Jayawardana, Zacky Haniffa

“…Consequences of coronavirus disease 2019 (COVID-19) in pregnancy have many implications in women’s lives other than unfavorable obstetric outcomes. In addition to managing acute respiratory illness and symptoms, caregivers should be equipped to detect and manage the short-term, intermediate, and long-term consequences of SARS-CoV-2 infection as well. …”
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Suppressive Activity of Vitamin D3 on Matrix Metalloproteinase Production From Cholesteatoma Keratinocytes In Vitro by Hitome Kobayashi, Kazuhito Asano, Ken-ichi Kanai, Harumi Suzaki

“…We also used ELISA to measure the levels of both TIMP (tissue inhibitor of metalloproteinase)-1 and TIMP-2 in culture supernatants. Addition of VD3 into keratinocyte cultures caused the suppression of MMP and TIMP production, which was increased by LPS stimulation. …”
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Instruments for assessing healthcare professionals’ knowledge, attitudes and practices regarding deprescribing: a scoping review protocol by Luciane Cruz Lopes, Jardel Corrêa de Oliveira, Luis Phillipe Nagem Lopes, Mariana Del Grossi Moura, Ana Carolina Figueiredo Modesto, Laís Lessa Neiva Pantuzza

“…Data will be presented as absolute and relative frequencies, a world heatmap, heatmaps, bar plots or as a word cloud when appropriate.Ethics and dissemination The findings from this review will be discussed with stakeholders and healthcare professionals directly involved in deprescribing processes. Additionally, the results will be disseminated through publications and conference presentations.Protocol registration https://osf.io/tgjyc/…”
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Inhibition of Cathepsin S Produces Neuroprotective Effects after Traumatic Brain Injury in Mice by Jianguo Xu, Handong Wang, Ke Ding, Xinyu Lu, Tao Li, Jiawei Wang, Chunxi Wang, Jian Wang

“…Inhibition of CatS significantly reduced the level of TBI-induced inflammatory factors in brain tissue and alleviated brain edema. Additionally, administration of LHVS led to a decrease in neuronal degeneration and improved neurobehavioral function. …”
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Mechanisms of manganese uptake and long-distance transport in the hyperaccumulator Celosia argentea Linn. by Wenxuan Jiang, Pingping Jiang, Shaohong You, Hui Qiu, Jie Liu, Xuehong Zhang, Mouyixing Chen

“…High concentrations of Mn and three organic acids (oxalic, citric, and malic) were detected in the xylem sap under Mn treatment, and Mn may be chelated with them in the xylem for transport from the root to the shoot. Additionally, rooting and leaf-sourcing experiments confirmed that accumulated Mn in mature leaves could be re-transported via the phloem. …”
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Transcriptome size matters for single-cell RNA-seq normalization and bulk deconvolution by Songjian Lu, Jiyuan Yang, Lei Yan, Jingjing Liu, Judy Jiaru Wang, Rhea Jain, Jiyang Yu

“…By maintaining transcriptome size variation, CLTS-normalized scRNA-seq enhances the accuracy of bulk deconvolution. Additionally, ReDeconv mitigates gene length effects and models expression variances, thereby improving deconvolution outcomes, particularly for rare cell types. …”
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Possible impact of use of a ketogenic diet in pregnancy on the fetus: Review of animal and human studies by Agata Miłosz, Justyna Michalczyk, Iwona Morawik, Klaudia Długoborska, Monika Gesek

“…Balanced diet sufficient in all nutrients is crucial to human development and health, especially for pregnant women, whose diet has a direct impact on the appropriate development of the fetus [1]. In addition, it may lead to epigenetic changes in the fetus that affect the child's health and functioning in adulthood [2]. …”
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Biowastes as sustainable catalysts for water treatment: A comprehensive overview by Hirpha Adugna Areti, Abas Siraj Hamda, Lata Deso Abo, Abdisa Jabesa, Melkiyas Diriba Muleta

“…Integrating advanced technologies, such as membrane filtration and advanced oxidation processes, further enhances the efficacy of these catalysts. Additionally, artificial intelligence and machine learning provide tailored solutions for optimizing catalyst design and enabling real-time monitoring. …”
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Transplantation of fecal microbiota from low to high residual feed intake chickens: Impacts on RFI, microbial community and metabolites profiles by Chunlin Xie, Qiying Liang, Jiaheng Cheng, Yushan Yuan, Lu Xie, Jian Ji

“…Using 16S rDNA sequencing and RandomForest analysis, Slackia, Peptococcus, Blautia, and Dorea were identified as key microbial markers associated with feed efficiency. Additionally, untargeted metabolomics identified common differential metabolites between HFMT and LRFI vs. …”
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Accelerated Convergence Method for Flow Field Based on DMD-POD Combined Reduced-Order Optimization Model by Jianhui Li, Jun Huang, Yahui Sun, Guoqiang Li

“…For the nonlinear Burgers equation, the proposed method also reduces the number of convergence steps by nearly 70%. Additionally, the performance of the proposed accelerated convergence method was further validated through the complex flow around a high-dimensional dual ellipsoid.…”
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Mechanistic PKPD modeling to describe cytokine release associated with CD3 T-cell engager therapies by Apolline Lefèvre, Apolline Lefèvre, Zinnia P. Parra-Guillen, Zinnia P. Parra-Guillen, Iñaki F. Trocóniz, Iñaki F. Trocóniz, Iñaki F. Trocóniz, Christophe Boetsch, Nicolas Frances

“…The model was developed to explore and test hypotheses regarding the mechanisms behind the decrease of cytokine release following two repeated TCE administrations.ResultsThe model is able to successfully reproduce the observed dynamics of cytokine levels associated with the initial and subsequent TCE doses, accounting for different dosing intervals. In addition, the model suggests a mechanism of action that uncouples cytokine release from tumor cell killing.DiscussionThis model provides an initial mechanistic framework to support the design of experiments and paves the way for the application of mathematical modeling to support clinical dosing regimen selection of any TCE.…”
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