Vascular injury in glomerulopathies: the role of the endothelium by Géssica Sabrine Braga Barbosa, Niels Olsen Saraiva Câmara, Felipe Lourenço Ledesma, Amaro Nunes Duarte Neto, Cristiane Bitencourt Dias

“…The endothelial cell, which naturally has anti-inflammatory and anti-thrombotic regulatory mechanisms, is particularly susceptible to damage caused by various etiologies and can become dysfunctional due to direct/indirect injury or a deficiency of protective factors. In addition, endothelial regulation and protection involve participation of the complement system, factors related to angiogenesis, the renin–angiotensin system (RAS), endothelin, the glycocalyx, the coagulation cascade, interaction between these pathways, interactions between glomerular structures (the endothelium, mesangium, podocyte, and basement membrane) and interstitial structures (tubules, arterioles and small vessels). …”
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Biomaterial-assisted organoid technology for disease modeling and drug screening by Yunyuan Shao, Juncheng Wang, Anqi Jin, Shicui Jiang, Lanjie Lei, Liangle Liu

“…In this review, we will explore the roles that various biomaterials play in organoid development, examine the fundamental principles and advantages of utilizing these technologies in constructing disease models, and highlight recent advances and practical applications in drug screening using disease-specific organoid models. Additionally, the challenges and future directions of organoid technology are discussed. …”
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How to support recovery phase for landslide through livelihoods? case study: Kulon Progo Regency, Indonesia by Setyawati Dewanti Diah, Jaenul Haq Jejen, Viviani Nurhanifah Nita, Bi Chuanchen

“…The findings reveal that human capital (0.376**), social capital (0.279***), physical capital (0.182*), and TSP (0.263***) have a direct effect on the recovery phase. Additionally, social capital (0.352***) and physical capital (0.180**) indirectly influence the recovery phase through TSP as a mediator. …”
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Experimental Evaluation of the Pathogenicity of Different Strains of Schistosoma mansoni by Antônio Aurélio Euzébio, Nádia Regina Borim Zuim, Arício Xavier Linhares, Luiz Augusto Magalhães, Eliana Maria Zanotti-Magalhães

“…The comparison among the three strains indicated that the SD strain, isolated in Campinas, presented a higher worm recovery relative to the number of penetrating cercariae. In addition, when compared to the SJ and BH strains, the SD strain demonstrated similar pathogenicity to the BH strain, with a greater quantity of granulomas in the viscera, as well as larger granulomas and eggs. …”
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Machine Learning and hybrid models for assessing climate change impacts on runoff in the Kasilian catchment, Northern Iran by Farhad Hajian, Hossein Monshizadeh Naeen

“…Input variables (temperature and rainfall) were generated using LARS-WG software, incorporating five climate models and the SSP585 scenario for future climate change studies. Additionally, these hybrid models were used to forecast runoff changes for the observed period (2007-2018) and future periods (2031-2050 and 2051-2070). …”
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Molecular and cellular mechanisms underlying peripheral nerve injury-induced cellular ecological shifts: Implications for neuroregeneration by Limao Wu, Jinglan He, Na Shen, Song Chen

“…This paper analyses the phenotypic changes of these cells after injury, the relevant factors affecting these changes, and how they coordinate with neurons and other cell types. In addition, it explores the potential mechanisms that mediate the behaviour of these cells. …”
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Current status of developed electrocatalysts for water splitting technologies: from experimental to industrial perspective by Duy Thanh Tran, Phan Khanh Linh Tran, Deepanshu Malhotra, Thanh Hai Nguyen, Tran Thien An Nguyen, Nguyen Tram Anh Duong, Nam Hoon Kim, Joong Hee Lee

“…Herein, we provide an overview of the current state and future directions of electrocatalysts and water electrolyzers for electrochemical H2 production. Additionally, we describe in detail the technological framework of electrocatalysts and water electrolyzers for H2 production as utilized by relevant global companies. …”
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Metaanalyzing Foucault’s Archaeology Theory by Masoud Zare Mehrjardy, Ali Yousofi, Saeideh Mirabi

“…The results show that although archeology is less important to researchers than genealogy; however, in addition to being an efficient theoretical approach to historical, sociological research, it provides a different perspective on society, history, knowledge, and knowledge; It is also a methodological approach with separate guidelines and with a fluid and flexible structure that can be used effectively in dynamic sociological, historical research and make it dynamic. …”
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Impact of Geological Factors on Marine Shale Gas Enrichment and Reserve Estimation: A Case Study of Jiaoshiba Area in Fuling Gas Field by Siyu Yu, Xixin Wang, Shaohua Li, Yuming Liu, Liming Xiao, Xin Liu, Wen Zhao, Jiaen Zhang

“…The results show that adsorbed gas content is positively correlated with total organic carbon and porosity; the larger specific surface area of samples with more clay minerals essentially contributes to shale gas enrichment. Additionally, the sealing of faults imposes a significant impact on shale gas accumulation. …”
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Anti-Inflammatory Effect of Emblica officinalis in Rodent Models of Acute and Chronic Inflammation: Involvement of Possible Mechanisms by Mahaveer Golechha, Vikas Sarangal, Shreesh Ojha, Jagriti Bhatia, Dharmveer S. Arya

“…However, at the dose of 700 mg/kg, HAEEO exhibited maximum anti-inflammatory activity in all experimental models, and the effects were comparable to that of the standard anti-inflammatory drugs. Additionally, in paw tissue the antioxidant activity of HAEEO was also measured and it was found that HAEEO significantly (P<0.001) increased glutathione, superoxide dismutase, and catalase activity and subsequently reduced lipid peroxidation evidenced by reduced malondialdehyde. …”
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Method development and application for the analysis of chiral organic marker species in ice cores by J. Schäfer, A. Beschnitt, F. Burgay, F. Burgay, T. Singer, T. Singer, T. Singer, M. Schwikowski, M. Schwikowski, M. Schwikowski, T. Hoffmann

“…The method combines a reversed-phase column in the first dimension and a chiral column in the second dimension in a simple instrumental setup with only one additional six-port valve. This novel method was successfully applied to selected ice-core samples from the Belukha Glacier in the Siberian Altai spread over the period 1870–1970 CE. …”
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Overexpression of a sorghum SnRK1βγ2 gene increases the biomass in Setaria viridis but not in rice by Chudamani Sharma Prakash, Lihua Wang, Qi Shen, Jieqin Li, Yi-Hong Wang

“…In addition, SbSnRK1βγ2 did not affect the panicle weight in sorghum, but its overexpression doubled the panicle weight in S. viridis in all four evaluated transgenic lines. …”
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Experimental Study on the Tensile Property of a Novel Oriented Linear Porous Metal by Bin Liu, Xin-gang Wang, Yong Tang, Wei Yuan, Chao-bin Fang, Zhen-ping Wan

“…A higher sintering temperature produced a higher tensile strength for the OLPM sintered in the temperature range of 700°C–900°C, but the strength decreased at 1000°C. In addition, the extension of holding time could also slightly affect the tensile strength. …”
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Finite Element Method Using a Characteristic-Based Split for Numerical Simulation of a Carbonate Fracture-Cave Reservoir by Liehui Zhang, Yuhui Zhou, Lei Zhao, Deliang Zhang

“…After discrete modeling, the Galerkin finite element method was used for numerical calculation of the single-phase free flow; the method maintains a high-precision result with low grid orientations during the simulation. In addition, because only one linear equation requires solving at each step, the solution is obtained quickly. …”
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Procedure of Active Residual Heat Removal after Emergency Shutdown of High-Temperature-Gas-Cooled Reactor by Xingtuan Yang, Yanfei Sun, Huaiming Ju, Shengyao Jiang

“…The results show that steam generator should be discharged and precooled; otherwise, boiling will arise and introduce a cold shock to the boiling tubes and tube sheet when coolant began to circulate prior to the helium. Additionally, in avoiding heat shock caused by the sudden load of helium, the helium circulation should be restricted to start with an extreme low flow rate; meanwhile, the coolant of steam generator (water) should have flow rate as large as possible. …”
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Thermodynamics and solar radiative analysis in Jeffery-Hamel flow through non-parallel channel by novel improved residual power series method by Mohamed Bouzidi, Mohsin Ul Haq, Ikram Ullah, Saira Shukat, Hijaz Ahmad, Mohammad Mahtab Alam, Hamid Khan, Marouan Kouki

“…It is observed that increasing thermal radiation parameter leads to a substantial increase in the temperature profile. Additionally, the heat transfer rate is 15 % more in diverging channel when compared with converging channel.…”
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Application of the Bayesian Model Averaging in Analyzing Freeway Traffic Incident Clearance Time for Emergency Management by Yajie Zou, Bo Lin, Xiaoxue Yang, Lingtao Wu, Malik Muneeb Abid, Jinjun Tang

“…The results show that the BMA approach has the capability of interpreting the causal relationship between explanatory variables and clearance time. In addition, the BMA approach can provide better prediction performance than the Cox proportional hazards model and the accelerated failure time models. …”
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Combined therapeutic option for NDM-producing Serratia Marcescens – an in vitro study from clinical samples by Balbina Chilombo Albano, Leticia Ramos Dantas, Gabriel Burato Ortis, Paula Hansen Suss, Felipe Francisco Tuon

“…However, time-kill curve analysis revealed no synergism or additive effect for combinations with the tested antimicrobials. …”
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Patient-derived xenografts from circulating cancer stem cells as a preclinical model for personalized pancreatic cancer research by Benedikt J. Wagner, Andreas Ettner-Sitter, Nicolas A. Ihlo, Merle Behr, Sebastian Koelbl, Stefan M. Brunner, Florian Weber, Bettina M. Rau, Hans J. Schlitt, Christoph Brochhausen, Rebecca Schoenmehl, Annalena Artinger, Dorothea Schott, Monika Pizon, Katharina Pachmann, Thiha Aung, Silke Haerteis, Christina Hackl

“…The number of tumorspheres and CETCs/CTCs was analyzed perioperatively in 25 pancreatic cancer patients. Additionally, an individual in vivo chorioallantoic membrane (CAM) culture system was used to generate PDXs from these tumorspheres. …”
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Role of Platelet Indices as a Potential Marker for Malaria Severity by Biruk Bayleyegn, Fikir Asrie, Aregawi Yalew, Berhanu Woldu

“…Hence, after reviewing recent literatures, elevation of mean platelet volume and platelet distribution width in addition to decreased plateletcrit and platelet counts is the known potential risk factor associated with warning signs of severe malaria. …”
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