Addressing the “Black Hole” of Low Back Pain Care With Clinical Decision Support: User-Centered Design and Initial Usability Study by Robert S Rudin, Patricia M Herman, Robert Vining

“… Abstract BackgroundLow back pain (LBP) is a highly prevalent problem causing substantial personal and societal burden. Although there are specific types of LBP, each with evidence-based treatment recommendations, most patients receive a nonspecific diagnosis that does not facilitate evidence-based and individualized care. …”
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Characterization of Shigella flexneri serotype 6 strains from geographically diverse low- and middle-income countries by Caitlin E. Gabor, Charlotte E. Chong, Jose M. Lemme-Dumit, Tracy H. Hazen, Kate S. Baker, Karen L. Kotloff, Irene N. Kasumba, Sharon M. Tennant, Henry Badji, M. Jahangir Hossain, Richard Omore, Benjamin Ochieng, Alex O. Awuor, Billy Ogwel, Jane Juma, Eileen M. Barry, David A. Rasko

“…This level of conservation has not been noted for other S. flexneri serotypes and is promising for vaccine and diagnostic assays to provide global Sf6-specific coverage.IMPORTANCEShigellosis is an ongoing global public health crisis with >270 million annual episodes among all age groups; however, the greatest disease burden is among children in low- and middle-income countries (LMIC). …”
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Cigarette Smoking Patterns Among Racial and Ethnic Groups With Chronic Lung Diseases During the COVID-19 Pandemic by Vijaya L. Seegulam, MPH, Caretia J. Washington, BS, Parvathy P. Surendran, BPT, Alyssa M. Falise, PhD, MSPH, Diana Gomez-Manjarres, MD, Catalina Lopez-Quintero, MD, MPH, PhD

“…Hispanic individuals had the lowest prepandemic rates of current cigarette smoking (10.5%); however, it was the only racial/ethnic group showing a significant change during the pandemic, with rates increasing to 14.9% during the pandemic. …”
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Assessing the Effect of Groundnut Shell Ash-Lime Stabilization of Reclaimed Asphalt Pavement for Road Construction. by Tumusiime, Innocent

“…RAP acceptance in road bases and subbases has been limited, because of the lack of laboratory and field performance data while large quantities of groundnut shell ash (GSA) are generated from the combustion of groundnut shell and also disposed in large quantities on production sites and production of Lime not only imposes financial burdens but also contributes to environmental degradation and carbon emissions. …”
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Factors Associated with Stunting in Children Under Five Years of Age: A Case of Buhara Sub County, Kabale District. by Namanya, Oliver

“…Under nutrition, especially stunting has continued to be a health burden among children of less than five years of age living in low- and middle-income countries. …”
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Effects of Switching to Netarsudil/Latanoprost Fixed Dose Combination from Various Latanoprost Regimens: The Phase 4 MORE Study by Bacharach J, Sadri E, Sawhney G, Kopczynski C, Merchea MM

“…The once-daily administration of netarsudil/latanoprost FDC and reduced treatment burden for those on latanoprost combined with additional agents may prove more manageable for patients.Keywords: glaucoma, intraocular pressure, prostaglandin analog, rho-kinase inhibitor…”
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A study of the psychological experience of patients with thromboembolism during pregnancy and after childbirth (孕产期血栓栓塞症患者真实心理体验的研究) by HU Jiali (胡嘉丽), HUANG Xuefang (黄学芳), XU Xiaoyun (徐晓耘), MENG Ya (孟雅)

“…Qualitative findings were distilled into two major themes: low disease knowledge and awareness among patients with thromboembolism during pregnancy and after childbirth; increased psychological burden as excessive fear of disease and concerns about fetus and newborns. …”
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The Concentration of Micronutrients and Heavy Metals in Maternal Serum, Placenta, and Cord Blood: A Cross-Sectional Study in Preterm Birth by Rima Irwinda, Noroyono Wibowo, Atikah Sayogo Putri

“…A cross-sectional study was conducted during January–June 2017 in Cipto Mangunkusumo Hospital and Budi Kemuliaan Hospital, Jakarta, Indonesia. …”
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Assessing the Effectiveness of Interactive Robot-Assisted Virtual Health Coaching for Health Literacy and Disease Knowledge of Patients with Chronic Kidney Disease: Quasiexperiment... by Nai-Jung Chen, Ching-Hao Chang, Chiu-Mieh Huang, Fen-He Lin, Li-Ting Lu, Kuan-Yi Liu, Chih-Lin Lai, Chin-Yao Lin, Yi-Chou Hou, Jong-Long Guo

“… BackgroundChronic kidney disease (CKD) imposes a significant global health and economic burden, impacting millions globally. Despite its high prevalence, public awareness and understanding of CKD remain limited, leading to delayed diagnosis and suboptimal management. …”
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DigiLoCS: A leap forward in predictive organ-on-chip simulations. by Manoja Rajalakshmi Aravindakshan, Chittaranjan Mandal, Alex Pothen, Stephan Schaller, Christian Maass

“…The aim is to develop digital twins capable of determining better predictions of clinical outcomes, ultimately reducing the time, cost, and patient burden associated with drug development. Various hepatic in vitro systems are compared and their effectiveness for predicting human clearance is investigated. …”
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Predicting Treatment Outcomes in Patients with Low Back Pain Using Gene Signature-Based Machine Learning Models by Youzhi Lian, Yinyu Shi, Haibin Shang, Hongsheng Zhan

“…Abstract Introduction Low back pain (LBP) is a significant global health burden, with variable treatment outcomes and an unclear underlying molecular mechanism. …”
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Research status and future prospect of carbon capture technology using steel slag in the context of carbon neutrality by Lei AN, Xiaoyuan ZHANG, Yu LIU

“…As the world’s largest steel producer, China generates substantial amounts of steel slag byproducts during the steel-making process, posing serious threats to the ecosystem. …”
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Frau im Rechtsalltag von Vilnius und Kaunas in der ersten Halfte des 16. Jhs: Zeichen des modem werdenden Lebens by Jolanta Karpavičienė

“… Die Forschungen der Frauengeschichte gewinnen in den letzten Jahren in Litauen an Intensität. Aber noch wenig ist das Thema über die Stellung der Frau in den litauischen Städten des Spätmittelalters und zu Beginn der Neuzeit erforscht. …”
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Beyond Chemistry: Investigating the Physical, Pharmacological, and Computational Aspects of Polyoxometalate Integrated Solid Lipid Nanoparticles for Cancer Treatment by Khan R, Tulain UR, Shah HS, Usman F, Chohan TA, Iqbal J, Kazi M, Ijaz M, Erum A, Malik NS, Mahmood A

“…The effectiveness of P5W30-BW-SLNs in inhibiting the growth of HeLa cells was found to be higher (IC50 = 3.02± 2.14 μg/mL) compared to pure P5W30 (IC50 = 7.93± 5.08 μg/mL). Further examinations of DNA damage were made through comet test and flow cytometry techniques. …”
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Effectiveness of a Mobile Health Intervention (DOT Selfie) in Increasing Treatment Adherence Monitoring and Support for Patients With Tuberculosis in Uganda: Randomized Controlled... by Juliet Nabbuye Sekandi, Esther Buregyeya, Sarah Zalwango, Damalie Nakkonde, Patrick Kaggwa, Trang Ho Thu Quach, David Asiimwe, Lynn Atuyambe, Kevin Dobbin

“…This evidence highlights the potential of digital technologies to improve treatment adherence monitoring and support in high TB burden settings with limited human resources. …”
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Endothelial Dysfunction and Oxidative Stress in Patients with Severe Coronary Artery Disease: Does Diabetes Play a Contributing Role? by Alexandra Maria Boieriu, Cezar Dumitrel Luca, Carmen Daniela Neculoiu, Alina Bisoc, Diana Țînț

“…<i>Results:</i> The coronary atherosclerotic burden, assessed using the SYNTAX I score, was more severe in patients with CAD and associated T2DM compared to those with CAD without T2DM (30.5 (17–54) vs. 29 (17–48); <i>p</i> = 0.05). …”
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Performance Evaluation of Large Language Models in Cervical Cancer Management Based on a Standardized Questionnaire: Comparative Study by Warisijiang Kuerbanjiang, Shengzhe Peng, Yiershatijiang Jiamaliding, Yuexiong Yi

“… BackgroundCervical cancer remains the fourth leading cause of death among women globally, with a particularly severe burden in low-resource settings. A comprehensive approach—from screening to diagnosis and treatment—is essential for effective prevention and management. …”
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Internal Facilitation by Health Assistants for the &ldquo;WHO Lay Health Worker Dementia Care&rdquo; in Rural Uganda: A Formative Evaluation by Wakida EK, Obua C, Rukundo GZ, Samantha M, Maling S, Karungi CK, Talib ZM, Haberer J, Bartels SJ

“…Early diagnosis and tailored care are essential for managing these symptoms, improving quality of life, and reducing caregiver burden. Dementia affects a substantial portion of older people globally, especially in low- and middle-income countries like Uganda, where rural healthcare systems face challenges in dementia care access. …”
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Biologic Therapy and Cardiometabolic Risk in Psoriasis: A Retrospective Review by Annika Smith, Aidin Karahasan, Deborah Yi, Sanjay Yapabandara, James Elhindi, Pablo Fernandez-Penas, Clara Chow, Sarah Zaman

“…Biologic therapy effectively treats the cutaneous inflammatory burden of psoriasis and evolving evidence suggests potential to reduce systemic inflammatory sequalae that can elevate cardiovascular risk. …”
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Proportion, quality of life and factors associated with perinatal urinary incontinence among pregnant women attending at Muhimbili national hospital by Geofrey P. Chiloleti, Fransia Arda Mushi, Aboud Muhsin, Ally Mwanga

Subjects: “…Perinatal urine incontinence…”
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