Problem of pain in the USA: evaluating the generalisability of high-impact chronic pain models over time using National Health Interview Survey (NHIS) data by Sean Mackey, Titilola Falasinnu, Md Belal Hossain, Mohammad Ehsanul Karim, Kenneth Arnold Weber

“…Introduction High-impact chronic pain (HICP) significantly affects the quality of life for millions of US adults, imposing substantial economic/healthcare burdens. Disproportionate effects are observed among racial/ethnic minorities and older adults.Methods We leveraged the National Health Interview Survey (NHIS) from 2016 (n=32 980), 2017 (n=26 700) and 2021 (n=28 740) to validate and develop analytical models for HICP. …”
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Glaucoma laser treatments: modern approaches and practice guidelines by M.H. Rabadanova, Zh.G. Oganezova, E.A. Egorov, D.V. Katz, V.V. Novoderezhkin

“…Filatov, Moscow, Russian Federation </p> <p> ³Research Center for Medical Genetics, Moscow, Russian Federation </p> <p> Glaucoma represents a significant medical, economical, and social burden for the healthcare system both in Russia and worldwide. …”
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Prevalence of depressive symptom and its associated factors among epilepsy patients in Amhara region, Ethiopia: cross-sectional study by Sintayehu Simie Tsega, Yilkal Abebaw Wassie, Alebachew Ferede Zegeye, Mekdes Kiflu, Sisay Maru Wubante, Kennean Mekonnen, Birhaneslasie Gebeyehu Yazew, Birye Dessalegn Mekonnen, Yeshambel Andargie Tarekegn

“…Epilepsy patients are identified as at higher risk of suffering depressive symptom explicitly in low- and middle-income countries due to poor mental health care systems and financial burdens. The co-occurrence of depressive symptom among epilepsy patients deteriorates the prognosis of the disease and diminishes the quality of life of both the patients and their families. …”
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CT45A1‐mediated MLC2 (MYL9) phosphorylation promotes natural killer cell resistance and outer cell fate in a cell‐in‐cell structure, potentiating the progression of microsatellite... by Hao‐Wei Teng, Hsiang‐Yueh Huang, Chun‐Chi Lin, Yuh‐Ching Twu, Wen‐Hao Yang, Wen‐Chun Lin, Hsin‐Yi Lan, Yen‐Yu Lin, Wei‐Lun Hwang

“…Patients with microsatellite instability‐high (MSI‐H) colorectal cancer (CRC) have high tumor mutation burden and tumor immunogenicity, exhibiting a higher response rate to immunotherapy and better survival. …”
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Dengue dynamics, predictions, and future increase under changing monsoon climate in India by Yacob Sophia, Mathew Koll Roxy, Raghu Murtugudde, Anand Karipot, Amir Sapkota, Panini Dasgupta, Kalpana Baliwant, Sujata Saunik, Abhiyant Tiwari, Rajib Chattopadhyay, Revati K. Phalkey

“…Abstract The global burden of dengue disease is escalating under the influence of climate change, with India contributing a third of the total. …”
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Flow Mediated Dilation and Its Correlation with Coronary and Systemic Atherosclerosis in Patients Scheduled for Surgical Myocardial Revascularization by Boieriu AM, Luca CD, Tint D

“…Additionally, we examined the association between the severity of EDevaluated throughFMD and the extent of atherosclerosis at the coronary arteries level (SYNTAX I score), carotid arteries and peripheral arteries.Methods: The study included 84 participants recruited between January 2020 and June 2021. Doppler ultrasonography was used to assess both FMD and the degree of carotid artery stenosis. …”
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Dual role of ramR mutation in enhancing immune activation and elevating eravacycline resistance in Klebsiella pneumoniae by Wei Yu, Peiyao Jia, Xiaobing Chu, Shengjie Li, Xinmiao Jia, Ying Zhu, Xiaoyu Liu, Yingchun Xu, Qiwen Yang

“…In mouse models, ramR L58P and F165L mutants showed lower bacterial burden in organs (spleen, lung, and kidney) 6 h post‐infection, and are fast cleared in 48 h. …”
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Prevalence and spectrum of haemoglobinopathies in females of reproductive age group- A first tertiary care center experience in Punjab, North India by Vikram Narang, Anshul Jain, Sumit Grover, Ankita Soni, Monika Narang, Ashima Taneja

“…According to estimates, approximately 7% of the world population is a carrier of Hb disorders, leading to high morbidity and mortality. To reduce the burden of these highly prevalent monogenic disorders, detecting them in the carrier stage is crucial to prevent disease progression. …”
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The prevalence and distribution of malaria in Mpumalanga Province before and during COVID-19 (2017 - 2022) by I Kleinhans, S Mahanjana, F Els, M Mabona, L A Pitso, G Malatje, G Kok, J Raman

“…To describe the trends and distribution of malaria before and during the pandemic and its associated lockdown strategies in one of the country’s malaria-endemic provinces, Mpumalanga Province. …”
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Early COVID-19 and protection from Omicron in a highly vaccinated population in Ontario, Canada: a matched prospective cohort study by Altynay Shigayeva, Christopher Kandel, Lubna Farooqi, Zoe Zhong, Anne-Claude Gingras, Brenda L. Coleman, Lois Gilbert, Wayne L. Gold, Maria Major, Tony Mazzulli, Samira Mubareka, Jelena Vojicic, Jingyan Yang, Pingping Zhang, Catherine Martin, Moe H. Kyaw, John M. McLaughlin, Allison McGeer

“…Abstract Objectives Predictions regarding the on-going burden of SARS-CoV-2, and vaccine recommendations, require an understanding of infection-associated immune protection. …”
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Costs and Resource Use Among Patients with Cervical Cancer, Cervical Intraepithelial Neoplasia, and Genital Warts in Algeria by Ali-Chakib Bennacef, Aomar Ammar Khodja, Fadl Allah Abou-Bekr, Tidiane Ndao, Ryan Holl, Goran Benčina

“…To assess the potential benefits of cervical cancer screening and HPV vaccination in North African countries, country-specific data on the prevalence and burden of HPV-related conditions are needed. **Objectives:** To describe the patterns and estimate the costs of management of cervical cancer, cervical intraepithelial neoplasia (CIN), and genital warts in Algeria. …”
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Factors associated with malnutrition inflammation score among hemodialysis patients: A cross-sectional investigation in tertiary care hospital, Palestine. by Zakaria Hamdan, Zaher Nazzal, Fatima Masoud Al-Amouri, Sanaa Ishtayah, Sarah Sammoudi, Lawra Bsharat, Manal Badrasawi

“…This study highlights the significant association between malnutrition and various demographic, clinical, functional, and dietary factors in hemodialysis patients, revealing the burden of malnutrition during HD. It also necessitates targeted intervention to address these risk factors and improve nutritional status and the overall health outcomes of HD patients.…”
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Nutritional assessment of adolescents: A cross-sectional study from public schools of North India. by Sandeep Kaur, Rajesh Kumar, Manmeet Kaur

“…Dietary patterns were recorded using two 24-hour recalls, and analyzed with PURE study software based on 2010 Indian dietary data from ICMR-NIN. …”
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Nature, prevalence and determinants of mental health problems experienced by adolescents in south Asia: a systematic reviewResearch in context by Chethana Mudunna, Medhavi Weerasinghe, Thach Tran, Josefine Antoniades, Lorena Romero, Miyuru Chandradasa, Jane Fisher

“…Mental health policies and programs and research appropriate to the cultural context, that address social determinants of MHPs and evidence gaps, are needed to tackle the significant mental health burden among south Asian adolescents. Funding: Authors CM and MW are supported by a Monash University Research Training Program Scholarship. …”
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Lifestyle risk factors for overweight and obesity among rural Indian adults: a community-based prospective cohort study by Rajesh Kumar Rai, Sabri Bromage, Jan-Walter De Neve, Anamitra Barik

“…India’s nutrition transition has led to an increased burden of overweight/obesity (body mass index of ≥23 kg/m2), driven by lifestyle factors like poor diet, inactivity, and substance use, prompting public health interventions. …”
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Cancer mortality and sectors of employment: a cohort study in Italy by Stefania Massari, Lisa Bauleo, Claudio Gariazzo, Paola Michelozzi, Luca Dei Bardi, Nicolas Zengarini, Sara Maio, Massimo Stafoggia, Marina Davoli, Giovanni Viegi, Giulia Cesaroni, Alessandro Marinaccio, on behalf of the BIGEPI Collaborative Group

“…The large impact of occupational exposure on the burden of cancer continues to be a paramount public health concern that deserves more attention. …”
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Knowledge, Attitude, and Practice towards COVID-19 among Mothers in Dessie Town, Northeast Ethiopia, 2020 by Debrnesh Goshiye, Zinet Abegaz, Sisay Gedamu

“…Coronavirus disease 2019 (COVID-19) is a highly infectious disease causing a catastrophic effect, and many of us are worried to find a new normal. Many burdens are occurring in households, predominantly to women and mothers. …”
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Anti-VEGF agents for the treatment of diabetic macular edema by S.G. Sergushev, E.N. Khomyakova

“…They result in a significant burden on patients and society. Until recently, laser retinal photocoagulation was recognized as the only treatment for DME. …”
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Worldwide patterns and trends in ovarian cancer incidence by histological subtype: a population-based analysis from 1988 to 2017Research in context by Yi-Fan Wei, Li Ning, Yi-Lin Xu, Jing Ma, Dong-Run Li, Zan-Fei Feng, Fang-Hua Liu, Yi-Zi Li, He-Li Xu, Peng Li, Yong-Pei Yu, Dong-Hui Huang, Xiao-Ying Li, Song Gao, Chun-Qing Lin, Ting-Ting Gong, Qi-Jun Wu, Jing-He Lang

“…Data were extracted from the Cancer Incidence in Five Continents (CI5 Ⅻ) and CI5plus databases (accessed in June 2024). Annual percent changes were computed to describe trends in age-standardized rates (ASRs) of OC and its subtypes. …”
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Prevalence of hypertension in Shenzhen, China: a population-based, cross-sectional study by Ke Peng, Ji Peng, Yirong Wang, Weicong Cai, Lin Lei, Rencheng Zhao, Fangjiang Liu, Kaihao Lin, Fengzhu Xie

“…Effective multifaceted implementation strategies are highly needed to combat the emerging burden of HTN.…”
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