Cardiovascular health in breast cancer patients: insight on BRCA1/2 mutations impact by Panagiotis Mallios, Mehdi Dehghan Manshadi, Laila Hubbert, Tajeri Aydin, Claudia Maes, Johanna Rantala, Annelie Liljegren, Narsis A. Kiani, Elham Hedayati

“…Sporadic-BC patients exhibited a higher overall cardiovascular burden, including arrhythmias, coronary artery disease, and stroke. …”
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Co-creation of a gender responsive TB intervention in Nigeria: a researcher-led collaborative study by Chukwuebuka Ugwu, Oluwatoyosi Adekeye, Beate Ringwald, Rachael Thomson, Obioma Chijioke-Akaniro, Chukwuma Anyaike, S Bertel Squire, John Bimba, Tom Wingfield

“…The higher TB risk and burden in men has implications for the whole population and reaching them earlier with TB services will reduce onward transmission in households, communities, and workplaces. …”
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Costs of outpatient services at selected primary healthcare centers in Bangladesh: A cross-sectional study. by Md Zahid Hasan, Gazi Golam Mehdi, Khadija Islam Tisha, Md Golam Rabbani, Mohammad Wahid Ahmed, Subrata Paul, Ziaul Islam, Shehrin Shaila Mahmood

“…Antenatal care had the highest cost burden at BDT 1,384, followed by respiratory illness at BDT 783 and urinary tract infection at BDT 670. …”
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Optimization, Characterization, and Antibacterial Activity of Copper Nanoparticles Synthesized Using Senna didymobotrya Root Extract by Bernard Otieno Sadia, Jackson Kiplagat Cherutoi, Cleophas Mecha Achisa

“…The economic burden and high mortality associated with multidrug-resistant bacteria is a major public health concern. …”
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A retrospective analysis of the malaria trend in Yemen over the sixteen-years, from 2006 to 2021 by Wadhah Hassan Edrees, Wadee Abdullah Al-Shehari

“…Conclusion It currently suggests a continuous increase in the malaria burden without specifying trends or fluctuations and is becoming a public health threat and causing widespread concern. …”
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Estimation of Knowledge, Attitude and Prevalence of Female Sex Dysfunction in Elderly Pakistani Women by Khola Noreen, Farah Ayyaz, Lubna Meraj, Tabinda Khalid, Javara Malik, Muhammad Akram Randhawa

“…Methods: A cross-sectional survey was conducted from 15 June 2022 to 15 June 2023, using a structured questionnaire after obtaining approval from the Ethical Review Board (ERB) of Rawalpindi Medical University (RMU), Rawalpindi. …”
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Measures of social connectedness in adult populations: a systematic review by Ruth Plackett, Joe Hulin, Clara Mukuria, Mark Clowes, Sheena E. Ramsay, Liam Spencer, Emma A. Adams, Jennifer Dykxhoorn, Kate Walters, David P. J. Osborn, Victoria Zamperoni, Oliver Jones, Scott Weich

“…Psychometric evidence was extracted relating to six general domains: conceptual model, content validity, reliability, construct validity, scoring and interpretability, and respondent burden and presentation. A narrative synthesis summarised these psychometric properties. …”
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Proposed framework for the integration of refractive error services into the eye health ecosystem in Kenya via social enterprise by Shadrack Muma, Kovin Shunmugam Naidoo, Rekha Hansraj

“…Abstract The global burden of uncorrected refractive error demands for adoption of different approaches inclined towards scaling effective refractive error coverage. …”
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Wnt/β-catenin signalling underpins juvenile Fasciola hepatica growth and development. by Rebecca Armstrong, Nikki J Marks, Timothy G Geary, John Harrington, Paul M Selzer, Aaron G Maule

“…Infection by the liver fluke, Fasciola hepatica, places a substantial burden on the global agri-food industry and poses a significant threat to human health in endemic regions. …”
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Impact of health education on knowledge retention among caregivers of hypertensive patients: A prospective cross-sectional study in rural Malawi. by Chikondi Maluwa, Sitalire Kapira, Hataichanok Chuljerm, Wason Parklak, Kanokwan Kulprachakarn

“…In low- and middle-income countries, like Malawi, the burden of hypertension is escalating due to inadequate healthcare resources and lifestyle changes. …”
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Prevalence of intestinal parasites and Helicobacter pylori co-infection in people with gastrointestinal symptoms in Africa: a systematic review and meta-analysis by Yenesew Mihret Wondmagegn, Getu Girmay, Gashaw Azanaw Amare, Muluneh Assefa, Mebratu Tamir, Zufan Yiheyis Abriham, Abebaw Setegn

“…Abstract Background Gastrointestinal infections caused by intestinal parasites and Helicobacter pylori are significant public health issues in Africa, where poor sanitation and limited access to healthcare contribute to high disease burden. Since there was no previous pooled data regarding the intestinal parasites and Helicobacter pylori co-infections among gastrointestinal symptomatic patients in the African context, this review aimed to determine the overall prevalence of intestinal parasites and Helicobacter pylori co-infection in people with gastrointestinal symptoms in Africa. …”
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Mathematical Modelling and Analysis of Transmission Dynamics of Lassa Fever by E. A. Bakare, E. B. Are, O. E. Abolarin, S. A. Osanyinlusi, Benitho Ngwu, Obiaderi N. Ubaka

“…Sub-Saharan Africa harbours the majority of the burden of Lassa fever. Clinical diseases, as well as high seroprevalence, have been documented in Nigeria, Sierra Leone, Liberia, Guinea, Ivory Coast, Ghana, Senegal, Upper Volta, Gambia, and Mali. …”
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Prevalence of Active Trachoma and Associated Factors in Areka Town, South Ethiopia, 2018 by Melese Menta Alambo, Eyasu Alam Lake, Shimelash Bitew Workie, Addisu Yeshambel Wassie

“…Globally, 1.2 billion people live in trachoma endemic areas, 40.6 million people are suffering from active trachoma, and 48.5% of the global burden of active trachoma is distributed in five countries including Ethiopia. …”
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Comprehensive Analysis of the Mechanism of Anoikis in Hepatocellular Carcinoma by Dongqian Li, Qian Bao, Shiqi Ren, Haoxiang Ding, Chengfeng Guo, Kai Gao, Jian Wan, Yao Wang, MingYan Zhu, Yicheng Xiong

“…Hepatocellular carcinoma (HCC), ranking as the second-leading cause of global mortality among malignancies, poses a substantial burden on public health worldwide. Anoikis, a type of programmed cell death, serves as a barrier against the dissemination of cancer cells to distant organs, thereby constraining the progression of cancer. …”
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Correlation analysis of the impact of Clonorchis sinensis juvenile on gut microbiota and transcriptome in mice by Xueling Deng, Shitao Li, Yuhong Wu, Jiali Yao, Wei Hou, Jiangyao Zheng, Boying Liang, Xiaole Liang, Qiping Hu, Zhanshuai Wu, Zeli Tang

“…ABSTRACT Clonorchiasis remains a non-negligible global zoonosis, imposing serious socio-economic burdens in endemic regions. The interplay between gut microbiota and the host transcriptome is crucial for maintaining health; however, the impact of Clonorchiasis sinensis juvenile infection on these factors is still poorly understood. …”
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Causal Inference for Hypertension Prediction With Wearable E lectrocardiogram and P hotoplethysmogram Signa... by Ke Gon g, Yifan Chen, Xinyue Song, Zhizhong Fu, Xiaorong Ding

“… Abstract Background Hypertension is a leading cause of cardiovascular disease and premature death worldwide, and it puts a heavy burden on the healthcare system. Therefore, it is very important to detect and evaluate hypertension and related cardiovascular events to enable early prevention, detection, and management. …”
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Review of Postgraduate Dissertations on Alzheimer's Patients in Nursing Care by Fadime Toru

“…When the subject distribution of the theses was analyzed, 42.8% were found to be related to the difficulties experienced by the caregivers (care burden). In the study, 76.2% of the theses were made as master's theses. …”
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Shed antigen-induced blocking effect on CAR-T cells targeting Glypican-3 in Hepatocellular Carcinoma by Wei Gao, Tong Ding, Beicheng Sun, Nan Li, Fang Gao, Meng Jia, Mitchell Ho, Na Li, Luan Sun, Zhanhui Gao, Lei Ao, Sujuan Ma, Peihua Lu, Shaochang Jia

“…In animal models, mice carrying Hep3B xenograft tumors expressing sGPC3 exhibited a worse response to the treatment with CAR-T cells under both a low and high tumor burden. sGPC3 bound to CAR-T cells but failed to induce the effective activation of CAR-T cells. …”
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Using positive deviance to enhance HIV care retention in South Africa: development of a compassion-focused program to improve the staff and patient experience by Allison J. Ober, Donald H. Skinner, Laura M. Bogart, Leletu Busakwe, Wadene Davids, Hassan Mahomed, Debbie Ling, Virginia Zweigenthal

“…Abstract Background HIV burden remains high in South Africa despite intensive efforts to curtail the epidemic. …”
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Under-nutrition and its associated factors among adult second-line antiretroviral treatment users in Northern Ethiopia by Seteamlak Adane Masresha, Atitegeb Abera Kidie, Getahun Fentaw Mulaw, Fentaw Wassie Feleke, Mesfin Wudu Kassaw, Tadesse Mamo Dejene, Aychew Kassie Gidafie, Fassikaw Kebede Bizuneh

“…Those populations also had a baseline undernutrition status of 39.1% (95%CI: 34.11–44.15) during their transition to SLART. The risk of being malnourished at six months of SLART initiation was fifteen times higher among those who were undernourished at SLART start (AOR:15.099, 95%CI: 8.532, 26.720) reflecting the high burden of the problem in the advanced courses of HIV/AIDS treatment and care. …”
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