Pooled prevalence and subgroup variations of Tetralogy of Fallot among children and adolescents with congenital heart defect in Sub-Saharan Africa: A systematic review and meta-ana... by Biniam Endale Geleta, Abay Mulu

“…Identifying the true scope of Tetralogy of Fallot burden may help policymakers and healthcare providers to prioritize interventions, optimize resource allocation, and potentially improve its outcomes in Sub-Saharan Africa.…”
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What are the Thoughts of Women Whose Husbands’ Frozen Testicular Sperm Is Thawed for in vitro Fertilization on the Day of Oocyte Retrieval? A Qualitative Study by He Y, Wei Q, Chen X, Zhang C, Wang Z

“…Yu He, Qun Wei, Xiaojie Chen, Chen Zhang, Zilian Wang Nursing Department, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou City, Zhejiang Province, People’s Republic of ChinaCorrespondence: Zilian Wang, Email Yanchen517@126.comObjective: The psychological experiences will be analyzed to understand the needs and burdens of women on the day of oocyte retrieval when the thawed testicular sperm of their husbands is used for in vitro fertilization, in order to provide a basis for the subsequent formulation of relevant nursing measures.Methods: This study utilized a descriptive phenomenological research approach. …”
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Assessing caregiver stress and resource needs in pediatric cancer care by Shaimaa Mohamed Amin, Mahmoud Abdelwahab Khedr, Azza Medhat Aziz Mansy, Ahmed Hashem El-Monshed, Mohamed Gamal Noaman Malek, Ayman Mohamed El-Ashry

“…Future research should explore sustainable strategies to further reduce caregiver burden. Clinical trial number Not applicable.…”
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Current challenges and implications for dengue, chikungunya and Zika seroprevalence studies worldwide: A scoping review. by Camille Fritzell, Dominique Rousset, Antoine Adde, Mirdad Kazanji, Maria D Van Kerkhove, Claude Flamand

“…<h4>Background</h4>Arboviral infections are a public health concern and an escalating problem worldwide. Estimating the burden of these diseases represents a major challenge that is complicated by the large number of unapparent infections, especially those of dengue fever. …”
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Errors Associated With Medication Administration by a Nurse During Hospitalisation: A Prospective Observational Multicentric Study by Ondrej Tesar, Martin Dosedel, Ales Antonin Kubena, Katerina Mala‐Ladova, Radka Prokesova, Iva Brabcova, Hana Hajduchova, Martin Cerveny, Ivana Chloubova, Jiri Vlcek, Valerie Tothova, Josef Maly

“…Implication for the Profession and Patient Care The identified determinants of MAE should be considered by hospital stakeholders in their support programs to reduce the level of burden for nurses during medication administration. …”
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Clinical and cost-effectiveness of a guided internet-based Acceptance and Commitment Therapy to improve chronic pain–related disability in green professions (PACT-A): study protoco... by Claudia Buntrock, Harald Baumeister, Yannik Terhorst, Lina Braun, Ingrid Titzler, Johanna Freund, Janika Thielecke, David Ebert

“…Introduction Chronic pain is highly prevalent, associated with substantial personal and economic burdens, and increased risk for mental disorders. …”
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Cost-effectiveness and budget impact analysis of peritoneal dialysis and haemodialysis in South Africa by Evelyn Thsehla, Micheal Kofi Boachie, Susan Goldstein

“…The cost of these therapies poses a significant burden to the health care system in South Africa. …”
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Enhancing food security while reducing environmental impacts: Life cycle assessment of cultivation-irrigation systems and yield gap closure in paddy fields by Abdullah Darzi-Naftchali, Markus Berger, Fereshteh Batoukhteh, Ali Motevali

“…Enhancing food and water security is crucial, not only by preventing additional burdens on the environment but also by significantly mitigating existing environmental challenges. …”
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Cardiovascular wellness in low-resource settings: A mobile app-based risk prediction study among fuel filling station employees in Puducherry district by Divyabharathy Ramadass, Jyothi Vasudevan, Madonna J. Dsouza, Baalaji Subramanian

“…Risk prediction assessment should be made mandatory during the annual examination of employees.…”
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Modelling the health, financial protection and equity impacts of upscaling the ACT NOW early intervention breast cancer pilot program in the Philippines: an extended cost-effective... by Blake Angell, Stephen Jan, Mark Woodward, Sanne Peters, Merel Kimman, Alexander Chye, Nirmala Bhoo Pathy, Herdee Gloriane C Luna, Soledad B Lim, Helen Monaghan, Corazon A Ngelangel

“…Introduction Women in the Philippines experience significant health and economic burdens of breast cancer. The Philippines has reformed financial protection for breast cancer but does not have a national early detection and treatment programme. …”
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Generating evidence on screening, diagnosis and management of non-communicable diseases during pregnancy; a scoping review of current gap and practice in India with a comparison of Asian context. by Theophilus Lakiang, Sonali Abner Daniel, Kauma Kurian C, Minashree Horo, Shumayla Shumayla, Sunil Mehra

“…There are no national guidelines for PIH diagnosis and management despite the increasing burden and contribution to maternal and perinatal morbidity and mortality. …”
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RUSSIA'S RELATIONS WITH THE EUROPEAN UNION AND CHINA: COMPARATIVE ANALYSIS OF MUTUAL PERCEPTION IN THE BORDER REGIONS by R. H. Simonyan, T. M. Kochegarova

“…In the upcoming modernization, the main burden of its implementation will fall on the current young generation of Russians. …”
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Prevalence and Factors Associated with Intestinal Parasitic Infections among Pregnant Women in West Gojjam Zone, Northwest Ethiopia by Tadesse Hailu, Bayeh Abera, Wondemagegn Mulu, Simachew Kassa, Ashenafi Genanew, Arancha Amor

“…Intestinal parasitic infections are the major causes of morbidity and mortality in sub-Saharan countries. The disease burden of these parasites is significantly high among pregnant women in developing countries like Ethiopia. …”
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mRNA-LNP vaccines combined with tPA signal sequence elicit strong protective immunity against Klebsiella pneumoniae by Ting Huang, Siyou Che, Zheng Lv, Danrui Hao, Runyu Wang, Qinxuan Yi, Ling Mei, Yang Yuan, Hang Zou, Yidong Guo, Xinrong Wang, Yiwen Chu, Kelei Zhao

“…This opportunistic pathogen causes severe infectious diseases, including urinary tract infection and pneumonia, and causes a concerning global public burden. Despite efforts having been created to develop different types of K. pneumoniae vaccines, there is no licensed vaccine for preventing K. pneumoniae infection. …”
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Unlocking the Potential of Receptor-Based Approaches in Diabetes Treatment by Mohsina Patwekar, Faheem Patwekar, J. Pavan Kumar, P. Dharani Prasad, Nazia Malik, A. Venkata Badarinath, Prashanth Parupathi, Konatham Teja Kumar Reddy, Selvaraja Elumalai, Zainul Abedeen Ab Samad

“…Diabetes, a common metabolic condition, poses a substantial health burden worldwide. To revolutionize diabetes management, enhance glycemic control, and decrease the risk of complications, recent research has revealed innovative targets and therapeutic options. …”
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Retinal optical coherence tomography intensity spatial correlation features as new biomarkers for confirmed Alzheimer’s disease by Zi Jin, Xinmin Wang, Ying Lang, Yufeng Song, Huangxiong Zhan, Wuge Shama, Yingying Shen, Guihua Zeng, Faying Zhou, Hongjian Gao, Shuling Ye, Yanjiang Wang, Fan Lu, Meixiao Shen

“…Moreover, the retinal OCT-ISCF were more strongly correlated with brain Aβ plaque burden and MoCA scores than retinal thickness. The accuracy using retinal OCT-ISCF (AUC = 0.935, 0.830) was better than that using retinal thickness (AUC = 0.795, 0.705) in detecting ADD and MCI. …”
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VACCIMEL, an allogeneic melanoma vaccine, efficiently triggers T cell immune responses against neoantigens and alloantigens, as well as against tumor-associated antigens by Ibel Carri, Ibel Carri, Erika Schwab, Juan Carlos Trivino, Erika M. von Euw, Morten Nielsen, Morten Nielsen, José Mordoh, María Marcela Barrio

“…We previously demonstrated that vaccination in the adjuvant setting prolonged the distant-metastasis-free survival of cutaneous melanoma patients and that T cells reactive to TAA and the patient’s private neoantigens increased during treatment. However, immune responses directed to vaccine antigens that may arise from VACCIMEL’s somatic mutations and human polymorphisms remain unexplored. …”
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Macrofocal multiple myeloma in the era of novel agents in China by Xuelin Dou, Ruixia Liu, Yang Liu, Nan Peng, Lei Wen, Daoxing Deng, Leqing Cao, Qian Li, Liru Wang, Fengrong Wang, Xiaodong Mo, Jin Lu

“…Prognostic staging and cytogenetic guidance for MFMM are often insufficient due to the low tumor burden in the bone marrow. Large cohort studies on this subgroup during the era of novel agents are limited. …”
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Human proximal tubular epithelial cell interleukin-1 receptor signalling triggers G2/M arrest and cellular senescence during hypoxic kidney injury by Kurt T. K. Giuliani, Purba Nag, Benjamin C. Adams, Xiangju Wang, Seokchan Hong, Anca Grivei, Rebecca L. Johnston, Nicola Waddell, Kenneth K. C. Ho, Yilin Tian, Muhammad Ali Khan, Chang Seong Kim, Monica S. Y. Ng, Glenda Gobe, Jacobus P. J. Ungerer, Josephine M. Forbes, Helen G. Healy, Andrew J. Kassianos

“…Treatment of Hypoxia+IL-1β-treated PTECs with either a type I IL-1 receptor (IL-1RI) neutralizing antibody or a senolytic drug combination, quercetin+dasatinib, attenuated senescent cell burden. In vitro findings were validated in human CKD bio-specimens (kidney tissue, urine), with elevated PTEC IL-1RI expression and senescence (SA-β-gal activity) detected in fibrotic kidneys and numbers of senescent (SA-β-gal+) urinary PTECs correlating with urinary IL-1β levels and severity of interstitial fibrosis. …”
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Long term outcomes associated with the use of perioperative systemic chemotherapy on low grade appendiceal mucinous neoplasms with pseudomyxoma peritonei treated with cytoreductive... by Samantha M. Ruff, Gyulnara Kasumova, Manoj Palavalli, Oliver S. Eng, Laura Lambert, Callisia Clarke, Sameer Patel, Jula Veerapong, Keith Fournier, Daniel Abbott, Charles Staley, Travis Grotz, Fabian Johnston, Mustafa Raoof, Sean Dineen, Jordan M. Cloyd, Alex C. Kim

“…Patients selected for systemic chemotherapy had a higher burden of disease (mean peritoneal cancer index: 18.8 +/- 8.6 versus 14.3 +/- 8.8, p&lt;0.001). …”
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