Medicinal Plants used for Cutaneous Wound Healing in Uganda; Ethnomedicinal Reports and Pharmacological Evidences. by Gang, Roggers, Okello, Denis, Kang, Youngmin

“…Background: Wounds have become a major health challenge worldwide, presenting marked humanistic and economic burdens such as disabilities and death. Annually, approximately 14 million people suffer from wounds worldwide and 80 % of these occur in developing countries like Uganda. …”
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Design and Simulation of a Cutting Mechanism for a Millet Harvesting Machine. by Twebazibwe, Edson

“…More so, this machine can harvest only millet heads and not the whole crop depending on the operator’s preference and therefore most farmers who are not livestock farmers will be relieved of the burden of sorting the millet heads from stalks as has been the case after harvesting. …”
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Genetic diversity and population structure of Plasmodium falciparum across areas of varied malaria transmission intensities in Uganda. by Mwesigwa, Alex, Tukwasibwe, Stephen, Cummings, Bryan, Kawalya, Hakiimu, Kiyaga, Shahiid, Okoboi, Stephen, Castelnuovo, Barbara, Bikaitwoha, Everd Maniple, Kalyango, Joan N., Nsobya, Samuel L., Karamagi, Charles, Byakika‑Kibwika, Pauline, Nankabirwa, Joaniter I.

“…Background: Malaria remains a significant global health threat, with sub-Saharan Africa (SSA) bearing the highest burden of the disease. Plasmodium falciparum is the predominant species in the region, leading to substantial morbidity and mortality. …”
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Tax Reforms and Domestic Revenue mobilization: A case Study of Uganda Revenue Authority Kabale Branch. by Hillary, Niwamanya

“…It was found out from 82% of the respondents that the challenges faced by tax authorities during domestic revenue mobilization in URA include; taxpayer compliance burden, lack of adequate resources to sustain and facilitate the operation of tax authorities, lack of modern technology, high levels of illiteracy and the problem of tax evasion and default. …”
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Charlson comorbidity index has no incremental value for mortality risk prediction in nursing home residents with COVID-19 disease by Anum Zahra, Maarten van Smeden, Petra J. M. Elders, Jan Festen, Jacobijn Gussekloo, Karlijn J. Joling, Anouk van Loon, Kim Luijken, René J. F. Melis, Simon P. Mooijaart, Karel G. M. Moons, Geeske Peeters, Harmke A. Polinder-Bos, Fenne Wouters, Anne de Hond

“…Abstract Background During the COVID-19 pandemic, nursing home (NH) residents faced the highest risk of severe COVID-19 disease and mortality. …”
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Integrated chronic care models for people with comorbid of HIV and non-communicable diseases in Sub-Saharan Africa: A scoping review. by Rumbidzai Chireshe, Tawanda Manyangadze, Keshena Naidoo

“…Duplication of limited resources is minimized, and a holistic care approach is promoted by shifting from acute and reactive care to care that embraces patient-centredness that includes promotive health and disease surveillance. The high burden of HIV disease in sub-Saharan Africa (SSA) combined with the increasing prevalence of chronic non-communicable diseases (NCDs) necessitates a review of how health systems has been doing to deliver quality integrated care for people living with HIV (PLWH) and comorbid chronic NCDs.…”
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Association between the triglyceride glucose body mass index and asthma: evidence from NHANES 2011–2018 by Sijia Yu, Shiping Wu, Shouxin Wei

“…Abstract Background Asthma is a common chronic respiratory disease whose increasing prevalence poses a significant burden to human health and the economy. Several studies indicate that insulin resistance (IR) is associated with asthma development. …”
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Atherogenic index of plasma and coronary artery disease: a systematic review and meta-analysis of observational studies by Ramin Assempoor, Mohammad Shahabaddin Daneshvar, Aryan Taghvaei, Alireza Sattari Abroy, Amir Azimi, John R. Nelson, Kaveh Hosseini

“…Abstract Background Atherogenic index of plasma (AIP), a novel logarithmic index that combines fasting triglyceride and high-density lipoprotein cholesterol concentrations, is associated with the burden of atherosclerosis. This study aimed to evaluate the relationship between AIP and coronary artery disease (CAD) risk, severity, and prognosis in populations with and without established CAD. …”
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Evaluation of the antidiarrheal activity of the 80% hydromethanolic crude extract and solvent fractions of Terminalia brownii Fresen (Combretaceae) leaves in Swiss Albino mice by Khalid Ibrahim Kassaw, Dawit Zewdu Wondafrash, Jibril Seid Yesuf, Mestayet Geta Mengistie

“…BackgroundAlthough diarrhea is a preventable disease, it continues to have a significant impact on global health, with the burden being much greater in Sub-Saharan Africa. Medicinal plants represent affordable and locally available resources to address many diseases, including diarrhea. …”
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Prevalence of Intestinal Parasites and Associated Factors Among Public Primary Second‐Cycle Schoolchildren in Debre Markos Town, Northwest Ethiopia: A Cross‐Sectional Study by Abtie Abebaw, Gebreselassie Demeke, Hylemariam Mihiretie Mengist, Mengistu Endalamaw, Gizew Damtie Demeke

“…ABSTRACT Background and Aims Intestinal parasitic infection is a common disease that causes significant morbidity and mortality in developing countries, including Ethiopia. The burden of intestinal parasites is worse in schoolchildren, which leads to absenteeism from school, lower cognitive ability, affects academic performance, and causes malnutrition and anemia. …”
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Spatiotemporal Correlation Analysis for the Incidence of Esophageal and Gastric Cancer From 2010 to 2019: Ecological Study by Zixuan Cui, Chen Suo, Yidan Zhao, Shuo Wang, Ming Zhao, Ruilin Chen, Linyao Lu, Tiejun Zhang, Xingdong Chen

“…MethodsThe data of esophageal and gastric cancer were sourced from the Global Burden of Disease (GBD). Spatial autocorrelation analysis using Moran I in ArcGIS 10.8 (Esri) was performed to determine spatial clustering of each cancer incidence. …”
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Study protocol for a Prospective Observational study of Safety Threats and Adverse events in Trauma (PrO-STAT): a pilot study at a level-1 trauma centre in Canada by Melissa McGowan, Charles Keown-Stoneman, Brodie Nolan, Teodor Grantcharov, Eliane M Shore, Anisa Nazir

“…Introduction Traumatic injuries are a significant public health concern globally, resulting in substantial mortality, hospitalisation and healthcare burden. Despite the establishment of specialised trauma centres, there remains considerable variability in trauma-care practices and outcomes, particularly in the initial phase of trauma resuscitation in the trauma bay. …”
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Pulmonary granuloma formation during latent Cryptococcus neoformans infection in C3HeB/FeJ mice involves progression through three immunological phases by Jovany J. Betancourt, Minna Ding, J. Marina Yoder, Issa Mutyaba, Hannah M. Atkins, Gabriela De la Cruz, David B. Meya, Kirsten Nielsen

“…We found that latently infected mice progress through three phases of granuloma formation where different immune profiles dominate: an early phase characterized by eosinophilia, high IL-4/IL-13, and C. neoformans proliferation in the lungs; an intermediate phase characterized by multinucleated giant cell formation, high IL-1α/IFNγ, granuloma expansion, and increased blood antigen levels; and a late phase characterized by a significant expansion of T cells, granuloma condensation, and decreases in lung fungal burden and blood antigen levels. These findings highlight a complex series of immune changes that occur during the establishment of granulomas that control C. neoformans in the lungs and lay the foundation for studies to identify critical beneficial immune responses to Cryptococcus infections.IMPORTANCECryptococcus neoformans is a fungal pathogen that disseminates from the lungs to the brain to cause fatal disease. …”
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Spatiotemporal dynamics and prevention strategies of cervical cancer incidence in Addis Ababa, Ethiopia: an ecological study by Mathewos Assefa, Eva Johanna Kantelhardt, Teferi Gedif Fenta, Tariku Shimels

“…These strategies are essential to effectively reduce the cervical cancer burden and improve health outcomes in the community.…”
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Development and feasibility of an mHealth intervention for psychoeducational support of Nigerian women diagnosed with breast cancer undergoing chemotherapy: A pilot randomized cont... by Oluwadamilare Akingbade, Ka Yi Hong, Oluwabukola Sharon Ayo, Adetutu Sefinat Alade, Moshood Akinwumi Lawal, Ibironke Elizabeth Somoye, Victoria Adediran, Olamide Sado, Ka Ming Chow

“…<h4>Background</h4>Breast cancer (BC) remains a significant health burden globally, with high incidence and mortality rates, particularly in Nigeria. …”
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Collaborative design of a care pathway for pharmacy-based PrEP delivery in Nigeria: insights from stakeholder consultation by Obinna I. Ekwunife, Theodora C. Omenoba, Ugochi Eyong, Valentine Okelu, Michael Alagbile, Ifeanyi Ume, Ambrose Eze, Aderinola Fisayo, Gloria Aidoo-Frimpong, Farah Shroff, Chimezie Anyakora

“…Nigeria is among the three countries with the highest burden. Despite free access to pre- and post-exposure prophylaxis (PrEP and PEP) in Nigerian hospitals, stigma, distance, and restrictive clinic hours hinder uptake, especially among vulnerable populations. …”
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lncRNA-KCNQ1OT1: A Potential Target in Exosomes Derived from Adipose-Derived Stem Cells for the Treatment of Osteoporosis by Shan-zheng Wang, Jun Jia, Chang-hong Chen

“…Osteoporosis is a worldwide medical and socioeconomic burden characterized by systemic impairment of bone strength and microstructure. …”
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Co-creation and application of a framework for the de-prioritization of urban communities during insecticide-treated bed net mass campaigns for malaria prevention and control in Kwara State, Nigeria by Ifeoma D. Ozodiegwu, Laurette Mhlanga, Eniola A. Bamgboye, Adeniyi F. Fagbamigbe, Cyril Ademu, Chukwu Okoronkwo, Joshua O. Akinyemi, Akintayo O. Ogunwale, IkeOluwapo O. Ajayi, Beatriz Galatas

“…Abstract Background Malaria continues to be a major cause of illness and death worldwide, particularly affecting children under the age of five and those living in high-burden countries like Nigeria. Long-lasting insecticidal nets (LLINs) are one of the effective interventions for malaria control and prevention. …”
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Perinatal outcomes and predictors of placental abruption: a retrospective study in an Ethiopian tertiary care center by Mesfin Tadese, Gebresenbet Getachew, Tirusew Nigussie Kebede, Toyba Ebrahim Yesuf, Saba Desta Tessema, Wogene Asefa Damesa, Gebeyehu Shumet Solomon

“…Despite its severity, there is a lack of comprehensive data on the burden, risk factors, and outcomes associated with placental abruption in the Ethiopian context. …”
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Nephroprotective Effect of Mesenchymal Stem Cell-Based Therapy of Kidney Disease Induced by Toxicants by Shujun Lin, Wenshan Lin, Chunling Liao, Tianbiao Zhou

“…Furthermore, a difference in blood urea nitrogen levels between the MSC treatment group and control group was observed for 2-3, 4-5, 6-8, and ≥28 days. …”
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