Incidence of methicillin, inducible clindamycin, and vancomycin resistance in Staphylococcus aureus clinical isolates in Gombe, Northeastern Nigeria by Haruna Adamu, Celestina T. Otegwu, Fatima B. Abdullahi, Babajide A. Tytler, Busayo O. Olayinka

“…Conclusion: This study highlights the incidence of MRSA and VRSA which poses a significant burden on healthcare systems.…”
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Realizing Decent Work in a "Sandwich" Position: Assessing VET Trainers' Working Conditions in Times of Multiple Transformations by Manuel Nicklich, Marco Blank, Sabine Pfeiffer

“…Although the VET trainers are accustomed to mastering different requirements and interests, in transformative times new challenges arise and intensify the already heavy burden on VET personnel. If these are not addressed and VET work is not organized as decent, this will also jeopardize the quality of the vocational training system in the medium term.  …”
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Exclusive Breast-Feeding Practice and Associated Factors among HIV-Positive Mothers in Governmental Health Facilities, Southern Ethiopia by Lewam Mebratu, Selamawit Mengesha, Yadessa Tegene, Abraham Alano, Alemayehu Toma

“…Globally, over 90% of HIV infections among children are due to mother-to-child transmission and breastfeeding accounts for 5–20% of the burden. Avoidance of inappropriate feeding practices and practicing exclusive breastfeeding is recommended to reduce mother-to-child HIV transmission, but it is hardly practiced. …”
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Pain medication tapering for patients with Persistent Spinal Pain Syndrome Type II, treated with Spinal Cord Stimulation: A RCT-study protocol of the PIANISSIMO study. by Maarten Moens, Cleo Lina Crunelle, Koen Putman, Elke Wuyts, Frenn Bultinck, Hubert Van Puyenbroeck, PIANISSIMO consortium, Lisa Goudman

“…Despite the evidence that SCS can reduce disability and reduce pain medication usage, only 25% of the patients is able to completely omit pain medication usage after 12 months of SCS. To tackle the high burden of patients who consume a lot of pain medication, tapering programs could be initiated before starting a trajectory with SCS. …”
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Impact of low-dose CT screening for lung cancer on ethnic health inequities in New Zealand: a cost-effectiveness analysis by Sue Crengle, Giorgi Kvizhinadze, Melissa McLeod, Peter Sandiford, Karen Bartholomew

“…Objective There are large inequities in the lung cancer burden for the Indigenous Māori population of New Zealand. …”
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Endovascular versus Surgical Lower Extremity Revascularization among Patients with Chronic Kidney Disease by Qingzheng Chen, Jialin Han, Gomathy Parvathinathan, Elsie Ross, Margaret R. Stedman, Tara I. Chang

“…Multiple factors must be considered when counseling patients with CKD, who have a high burden of comorbid conditions. Clinical trials should include more patients with kidney disease, who are often otherwise excluded from participation, to better understand the most effective treatment strategies for this vulnerable patient population.…”
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Infestation of Ixodidae Ticks in Cattle: Prevalence and Associated Risk Factors in Ambo District, Western Ethiopia by Addis Kassahun Gebremeskel, Berhanu Mekibib, Bekele Dabesa

“…A cross sectional study was conducted in Ambo district, Western Ethiopia from October, 2018 to June, 2019 with the objectives of determining the prevalence, identifying the associated risk factors and the tick species of cattle in the area. …”
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Gender differences in use of cigarette and non-cigarette tobacco products among adolescents aged 13–15 years in 20 African countries by Israel T. Agaku, Rose Sulentic, Adriana Dragicevic, Gibril Njie, Candace K. Jones, Satomi Odani, Tina Tsafa, Joy Gwar, Constantine I. Vardavas, Olalekan Ayo-Yusuf

“…Differential gender patterns of cigarette and non-cigarette tobacco product use among youth may have implications for future disease burden. As the tobacco control landscape evolves, tobacco prevention efforts should focus on all tobacco products, not just cigarettes.…”
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Population Health Management to identify and characterise ongoing health need for high-risk individuals shielded from COVID-19: a cross-sectional cohort study by Adrian Pratt, Richard Wood, Charlie Kenward, Sam Creavin, Jennifer A Cooper

“…The study was performed at a time considered to be relatively early in the COVID-19 pandemic in the UK.Participants 1 013 940 individuals from 78 contributing general practices.Results Compared with the groups considered at ‘low’ and ‘moderate’ risk (ie, eligible for the annual influenza vaccination), individuals at high risk were older (median age: 68 years (IQR: 55–77 years), cf 30 years (18–44 years) and 63 years (38–73 years), respectively), with more primary care/community contacts in the previous year (median contacts: 5 (2–10), cf 0 (0–2) and 2 (0–5)) and had a higher burden of comorbidity (median Charlson Score: 4 (3–6), cf 0 (0–0) and 2 (1–4)). …”
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The impact of intermittent preventive treatment in school aged children with dihydroartemisinin piperaquine and artesunate amodiaquine on IgG response against six blood stage Plasm... by Eric Lyimo, Geofrey Makenga, Louise Turner, Thomas Lavstsen, John P A Lusingu, Jean-Pierre Van Geertruyden, Daniel T R Minja, Christian W Wang, Vito Baraka

“…Several interventional strategies have been implemented in malaria endemic areas where the burden is high, that include among others, intermittent preventive treatment (IPT), a tactic that blocks transmission and can reduce disease morbidity. …”
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Distinguishing classes of neuroactive drugs based on computational physicochemical properties and experimental phenotypic profiling in planarians. by Danielle Ireland, Christina Rabeler, Sagar Rao, Rudy J Richardson, Eva-Maria S Collins

“…Mental illnesses put a tremendous burden on afflicted individuals and society. Identification of novel drugs to treat such conditions is intrinsically challenging due to the complexity of neuropsychiatric diseases and the need for a systems-level understanding that goes beyond single molecule-target interactions. …”
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Association between drinking patterns and diabetic kidney disease in United States adults: a cross-sectional study based on data from NHANES 1999–2016 by Xusheng Yang

“…These findings suggest that moderate drinking frequency may not exacerbate renal burden in individuals with diabetes and provide new perspectives for clinical interventions.…”
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Trends in incidence, prevalence, and mortality of non-communicable diseases in Iraq (2003–2021) by Mohammed Merzah

“…Methods Data from the Global Burden of Disease (GBD) Study 2021 were utilized. …”
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The safety and efficacy of neutral electrolyzed water solution for wound irrigation: post-market clinical follow-up study by Veronika Valdová, Vladimíra Štěpánová, Lenka Lapčíková

“…IntroductionChronic wounds are a significant public health challenge, representing a considerable burden on the healthcare system. There are numerous gaps in knowledge in the treatment of chronic wounds. …”
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Determinants of mortality and prolonged hospital stay among dengue patients attending tertiary care hospital: a cross-sectional retrospective analysis by Yusra Habib Khan, Tauqeer Hussain Mallhi, Amer Hayat Khan, Azmi Sarriff, Azreen Syazril Adnan

“…Objectives Dengue imposes substantial economic, societal and personal burden in terms of hospital stay, morbidity and mortality. …”
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Prognostic significance of MRD and its correlation with arsenic concentration in pediatric acute promyelocytic leukemia: a retrospective study by SCCLG-APL group by Zhong Fan, Liang-Chun Yang, Yi-Qiao Chen, Wu-Qing Wan, Dun-Hua Zhou, Hui-Rong Mai, Wan-Li Li, Li-Hua Yang, He-Kui Lan, Hui-Qin Chen, Bi-Yun Guo, Zi-Jun Zhen, Ri-Yang Liu, Guo-Hua Chen, Xiao-Qin Feng, Cong Liang, Li-Na Wang, Yu-Li, Jie-Si Luo, Dan-Ping Huang, Xue-Qun Luo, Bin Li, Li-Bin Huang, Xiao-Li Zhang, Yan-Lai Tang

“…We also demonstrate a negative correlation between blood arsenic concentration levels and MRD, suggesting that lower arsenic concentrations during induction therapy may contribute to a higher MRD burden. …”
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Predictive role of modifiable factors in stroke: an umbrella review by Yue Wang, Lu Wen, Xiaotong Wang, Man Liang, Fanxin Zeng, Yuetian Yang, Fangfang Nie, Mengke Shang, Na Ta, Lanxin Ou, Zhibin Yang, Wanyang Liu

“…After sensitivity analyses, evidence of DASH diet, magnesium and depression turned to weak. No publication bias existed, except only one study which could be explained by reporting bias.Discussion Diet with rich macronutrients and micronutrients, healthy dietary patterns and favourable physical, emotional health and environmental management should be promoted to decrease the burden of stroke.PROSPERO registration number CRD42021249921.…”
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Associations of urinary caffeine metabolites with sex hormones: comparison of three statistical models by Jianli Zhou, Linyuan Qin, Linyuan Qin

“…In the BKMR model, despite no significant difference in the overall association between caffeine metabolites and the sex hormones (E2, TT, SHBG), there was nonetheless a declining trend in the male population E2 group, in the male and female population SHBG groups also observed a downward trend.ConclusionWhen considering the results of these three models, the whole-body burden of caffeine metabolites, especially the caffeine metabolites in the PC2 metabolic pathway was significantly negatively associated with E2 in males. …”
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A longitudinal study of the association between the outcome of bariatric surgery and mental health indicators in Chinese patients: an examination of the interaction effect by Hung-Yen Lin, Te-Chang Changchien, Tsung-Jen Hsieh, Cheng-Sheng Chen, Yung-Chieh Yen

“…Besides the physical burden, obesity is also associated with mental health issues. …”
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Identifying high-risk population segments for underweight, overweight, and obesity among reproductive-age women in sub-Saharan Africa by Amare Abera Tareke, Amare Abera Tareke, Anissa Mohammed, Amare Muche, Yeshimebet Ali

“…BackgroundDespite significant progress in addressing underweight in developing countries, the recent rise in the number of overweight and obese individuals has confirmed that the double burden of malnutrition will remain a crucial problem in the foreseeable future. …”
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