Prevalence of Coronary Endothelial and Microvascular Dysfunction in Women with Symptoms of Ischemia and No Obstructive Coronary Artery Disease Is Confirmed by a New Cohort: The NHL... by R. David Anderson, John W. Petersen, Puja K. Mehta, Janet Wei, B. Delia Johnson, Eileen M. Handberg, Saibal Kar, Bruce Samuels, Babak Azarbal, Kamlesh Kothawade, Sheryl F. Kelsey, Barry Sharaf, Leslee J. Shaw, George Sopko, C. Noel Bairey Merz, Carl J. Pepine

“…This study confirms prevalence of CMD in the contemporary WISE-CVD cohort similar to that of the original WISE cohort, despite a lower risk factor burden in WISE-CVD. Because these coronary functional abnormalities predict major adverse cardiac events, clinical trials of therapies targeting these abnormalities are indicated.…”
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ANTHROPOLOGICAL FOUNDATIONS OF THE CONCEPT OF "CRIME" IN HISTORICO-PHILOSOPHICAL DISCOURSE by I. O. Kovnierova

“…The second Theocentric considers a man the image and likeness of God, though he is at the same time burdened with original sin. In the era of early Modernism, the third paradigm, which we called cognitive-centric, becomes dominant, since the essence of a man is reduced primarily to his mind. …”
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Comprehensive analysis of heat shock protein 110, 90, 70, 60 families and tumor immune microenvironment characterization in clear cell renal cell carcinoma by Wenjing Liao, Mao Huang, Xiaoyi Du, Liangdan Tang, Junwu Li, Qin Tang

“…Our signature played a pivotal role in predicting tumor immune microenvironment, immune checkpoint gene expression, drug sensitivity, and tumor mutational burden (TMB) in patients with ccRCC. Our cellular experiments confirmed HSPA7 promotes the proliferation, invasion and metastasis of ccCRC cells. …”
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GPR55 in the tumor microenvironment of pancreatic cancer controls tumorigenesis by Dušica Ristić, Thomas Bärnthaler, Eva Gruden, Melanie Kienzl, Laura Danner, Karolina Herceg, Arailym Sarsembayeva, Julia Kargl, Rudolf Schicho

“…Notably, anti-PD-1 immunotherapy increased tumor burden in WT mice, while this effect was absent in the GPR55 KO mice. …”
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Measurement and Spatial Transfer of Blue Water Footprint in Urumqi-Changji-Shihezi Megalopolis——Based on MRIO Model by LYU Zhengyin, SUN Jianguang

“…To find a way to alleviate the pressure on water resources during the coordinated development of the Urumqi-Changji-Shihezi megalopolis,this paper calculated the blue water footprint in the megalopolis from the perspectives of production and consumption with a city-scale multi-region input-output (MRIO) model.The pattern of spatial transfer among the sectors of the region and between the region and the rest of the country was also measured.The results lead to the following conclusions:① In 2012,the blue water footprint of production in the Urumqi-Changji-Shihezi megalopolis was 3.383 billion m³,mainly due to the large production scale of the agriculture,forestry,animal husbandry,and fishery in Changji.In contrast,the blue water footprint of consumption was as high as 6.403 billion m³ because Urumqi and Shihezi imported a lot of blue water footprint in the primary industry (mainly from inside Xinjiang) and the tertiary industry (mainly from outside Xinjiang).② The self-sufficiency of the Urumqi-Changji-Shihezi megalopolis is limited.Nevertheless,the various sectors of each city are closely related to each other,and those in Shihezi are especially prominent in pulling the region's water consumption up to a high level.③ The Urumqi-Changji-Shihezi megalopolis has a net import of blue water footprint from within Xinjiang that is higher than its net export to outside Xinjiang.Specifically,Urumqi achieves a net import from both inside and outside Xinjiang and has a net export only in the sectors of petroleum,coking products,and processed nuclear fuel products.In contrast,Changji,presenting itself with a net export,and Shihezi,with a net import,rely on the inflow from the primary and tertiary industries within Xinjiang on the one hand and are burdened with the demand of major agricultural provinces outside Xinjiang and the developed provinces and cities in Southeast China for agricultural and livestock products and primary industrial products on the other hand.This research can thus provide a reference for the rational allocation of water resources in the Urumqi-Changji-Shihezi megalopolis and the strategic arrangement for foreign trade.…”
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Interest in digital health tools for miscarriage support: A qualitative assessment of Canadian women facing early pregnancy loss by Breanna Flynn, Anjali Sergeant, Genevieve Tam, Megan Gomes, Roopan Gill

“…In Canada, resources to support individuals and their partners facing EPL remain scarce despite a high burden of psychosocial sequelae. Digital health tools hold the potential to fill important gaps in reproductive healthcare. …”
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Risk factors of multidrug resistant tuberculosis among patients with tuberculosis at selected multidrug resistance treatment initiative centres in southern Ethiopia: a case-control... by Fantahun Admassu, Ermias Abera, Addisalem Gizachew, Tagesse Sedoro, Taye Gari

“…Controls were all patients with bacteriological (molecular) proven drug-susceptible TB strains and whose recent smear results were turned to negative and registered as cured. Both bivariate and multivariable logistic regression analysis was used to identify risk factors of MDR-TB infections.Main outcome measure Identifying the risk factors for MDR-TB.Results A total of 392 participants (79 cases and 313 controls) were interviewed. …”
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Examining the reach of a diabetes screening program in an urban emergency department by Ruth A. Pobee, Kirstie K. Danielson, Angela Kong, Yuval Eisenberg, Brian T. Layden, Janet Lin

“…Furthermore, most patients screened for prediabetes and diabetes reside in resource poor neighborhoods on the west and south sides of Chicago. Conclusion: The burden of prediabetes and diabetes were greater among non-Hispanic Black females, with a high prevalence of prediabetes observed among younger individuals, particularly those residing in resource poor neighborhoods in the west and south sides of Chicago. …”
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Activity of ceftolozane/tazobactam and comparators against gram-negative bacilli: Results from the Study for Monitoring Antimicrobial Resistance Trends (SMART – Brazil), 2018‒2021... by Amanda Azevedo Bittencourt, Vinicius Lima Faustino, Paula de Mendonça Batista, Lays Paulino Leonel, Marina Della Negra de Paula, Thales José Polis

“…Ceftolozane/tazobactam remained highly active against E. coli isolates during both 2018‒2019 (96.0 %) and 2020‒2021 (98.5 %). …”
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Cost-effectiveness and budget impact of covering Burkitt lymphoma in children under Ghana’s National Health Insurance Scheme by Richmond Owusu, Dakota Pritchard, Lieke Fleur Heupink, Godwin Gulbi, Brian Asare, Ivy Amankwah, Joycelyn Azeez, Martha Gyansa-Lutterodt, Lydia Dsane-Selby, Ruby Aileen Mensah, William Omane-Adjekum, Francis Ruiz, Mohamed Gad, Justice Nonvignon, Lumbwe Chola, Ghana Health Technology Assessment Technical Working Group

“…Delayed care seeking and treatment abandonment, often due to the financial burden of care seeking to families, are common reasons for a relatively low overall survival (OS) in low-and middle-income countries. …”
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A scoping review and prevalence analysis of soil-transmitted helminth infections in Honduras. by Ana Lourdes Sanchez, José Antonio Gabrie, María Mercedes Rueda, Rosa Elena Mejia, Maria Elena Bottazzi, Maritza Canales

“…<h4>Methods</h4>A systematic search was conducted of the published and grey literature to identify scientific work on the impact and prevalence of STH infections done between May 1930 and June 30, 2012. International databases and Honduran journals were searched. …”
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A comparison of CXR-CAD software to radiologists in identifying COVID-19 in individuals evaluated for Sars CoV-2 infection in Malawi and Zambia. by Sam Linsen, Aurélie Kamoun, Andrews Gunda, Tamara Mwenifumbo, Chancy Chavula, Lindiwe Nchimunya, Yucheng Tsai, Namwaka Mulenga, Godfrey Kadewele, Eunice Nahache Kajombo, Veronica Sunkutu, Jane Shawa, Rigveda Kadam, Matthew Arentz

“…AI based software, including computer aided detection software for chest radiographs (CXR-CAD), was developed during the pandemic to improve COVID-19 case finding and triage. …”
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Strategies to Promote ResiliencY (SPRY): a randomised embedded multifactorial adaptative platform (REMAP) clinical trial protocol to study interventions to improve recovery after s... by Derek C Angus, Jennifer Holder-Murray, Katherine Moll Reitz, Christopher W Seymour, Jennifer Vates, Melanie Quintana, Kert Viele, Michelle Detry, Michael Morowitz, Alison Morris, Barbara Methe, Jason Kennedy, Brian Zuckerbraun, Timothy D Girard, Oscar C Marroquin, Stephen Esper, Anne B Newman, Scott Berry, Matthew Neal

“…Embedding reduces the administrative burden of a traditional trial while accessing and rapidly analysing routine patient care EHR data. …”
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Moderate regular physical exercise can help in alleviating the systemic impact of schistosomiasis infection on brain cognitive function by Inssaf Berkiks, Inssaf Berkiks, Nada Abdel Aziz, Nada Abdel Aziz, Nada Abdel Aziz, Blessing Moses, Blessing Moses, Tiroyaone Brombacher, Tiroyaone Brombacher, Frank Brombacher, Frank Brombacher

“…In our study, we utilized a murine model of Schistosoma mansoni infection to investigate the cognitive impact of schistosomiasis. …”
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The incidence of outpatient care within 24 months from SARS-CoV-2 infection in the general population: a multicenter population-based cohort study by Federico Banchelli, Carlo Gagliotti, Angela De Paoli, Rossella Buttazzi, Elena Narne, Enrico Ricchizzi, Silvia Pierobon, Ugo Fedeli, Gisella Pitter, Elisa Fabbri, Michele Tonon, Elisa Gentilotti, Maurizia Rolli, Evelina Tacconelli, Maria Luisa Moro, Francesca Russo, Elena Berti

“…Conclusion Long-term effects of COVID-19 include an increase in the healthcare burden especially in the first months after the acute infection. …”
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A scoping review of lesbian, gay, bisexual, transgender, queer, and intersex (LGBTQI+) people's health in India. by Venkatesan Chakrapani, Peter A Newman, Murali Shunmugam, Shruta Rawat, Biji R Mohan, Dicky Baruah, Suchon Tepjan

“…Overall, studies reported high prevalence of HIV and sexually transmitted infections; multilevel risk factors for HIV; high levels of mental health burden linked to stigma, discrimination, and violence victimization; and non-availability of gender-affirmative medical care in government hospitals. …”
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An assessment of compliance with proposed regulations to restrict on-package marketing of packaged foods to improve nutrition in South Africa by Safura Abdool Karim, Tamryn Frank, Alice S. Khan, Morongoa G. Tlhako, Sikhumbule K. Joni, Elizabeth C. Swart

“…Abstract Background Ultra-processed products (UPPs), high in sugar, fat and sodium, contribute to increasing burdens of obesity and non-communicable diseases in South Africa (SA). …”
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Kidney Disease-Specific Quality of Life among Patients on Hemodialysis by Issa Al Salmi, Pramod Kamble, Eilean Rathinasamy Lazarus, Melba Sheila D’Souza, Yaqoob Al Maimani, Suad Hannawi

“…People on low incomes experienced social difficulties, while the maximum burden was found in physical activities and minimum social function. …”
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COVID-19 vaccination and cerebral small vessel disease progression—A prospective cohort study by Yiu Ming Bonaventure Ip, Sangqi Pang, Alan Yao, Lucas Lau, Anki Miu, Katarina Chiu, Ho Ko, Andrew Kwok, Helen Y Chan, Sharon Lee, Howard Chan, Trista Hung, Bonnie Lam, Vincent Hui, Haipeng Li, Lin Shi, Jill Abrigo, Xinyi Leng, Yannie Soo, Sze Ho Ma, Vincent CT Mok, Hugh S Markus, Chris Mok, David SC Hui, Thomas W Leung

“…Conclusions: BNT162b2 and CoronaVac did not increase cSVD burden in community-dwelling citizens. The association between surrogate virus neutralization test and cSVD progression among BNT162b2 recipients requires further investigation.…”
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Integration of a specialist pharmacist-led multidisciplinary team in primary care: preventing strokes in people with atrial fibrillation across North East London by Riyaz Patel, Sotiris Antoniou, Shabana Ali, Mital Patel, Matt Kearney, Jagjot Kaur Chahal, John Robson, Paul Wright, Afzal Sohaib, Richard Clements, Angela Theodoulou

“…Using digital ‘proactive care frameworks’ created by UCLPartners and the Clinical Effectiveness Group, Queen Mary University of London, baseline searches of GP records enabled clinical teams to risk stratify and prioritise patients with AF for review. …”
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