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  1. 5761

    Telehealth interventions for substance use disorders in low- and- middle income countries: A scoping review. by Margaret Isioma Ojeahere, Sarah Kanana Kiburi, Paul Agbo, Rakesh Kumar, Florence Jaguga

    Published 2022-11-01
    “…The increasing prevalence and magnitude of harmful effects of substance use disorders (SUDs) in low- and middle-income countries (LMICs) make it imperative to embrace interventions which are acceptable, feasible, and effective in reducing this burden. Globally, the use of telehealth interventions is increasingly being explored as possible effective approaches in the management of SUDs. …”
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  2. 5762

    Using artificial intelligence to predict post-operative outcomes in congenital heart surgeries: a systematic review by Ida Mohammadi, Shahryar Rajai Firouzabadi, Melika Hosseinpour, Mohammadhosein Akhlaghpasand, Bardia Hajikarimloo, Sam Zeraatian-Nejad, Peyman Sardari Nia

    Published 2024-12-01
    “…Abstract Introduction Congenital heart disease (CHD) represents the most common group of congenital anomalies, constitutes a significant contributor to the burden of non-communicable diseases, highlighting the critical need for improved risk assessment tools. …”
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  3. 5763

    Evaluating the cost-effectiveness of prosthetic rehabilitation for partially edentulous teeth in India: A comparative study of Clasp-Retained RPDs, Thermoplastic Resin RPDs, and Ca... by Subhash V, Aswini Kumar K, Vineetha Karuveettil

    Published 2025-03-01
    “…Background: With rising life expectancy, partial edentulism has increased, particularly in developing nations where economic constraints, limited awareness, and inadequate dental care exacerbate the burden on aging populations. Patients with fewer than 20 teeth often experience a reduction in Oral Health-Related Quality of Life (OHRQoL), emphasizing the need for effective tooth replacement. …”
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  4. 5764

    Depressive symptoms and overwork among physicians employed at a university hospital in Japan by Toru Maruyama

    Published 2017-11-01
    “…Methods: This study used a questionnaire recommended by the Japanese Ministry of Health for hospital physicians working overtime, administered through an interview carried out by an occupational physician during the health surveillance to evaluate: 1) the severity of chronic fatigue; 2) the burden of work; 3) an overwork score derived from these two measures; and 4) presence of depressive symptoms. …”
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  5. 5765

    Perceptions of Cardiovascular Healthcare Professionals Regarding Clinical Trials: A Survey-Based Study from the Middle East by Zainab Atiyah Dakhil, Hasan Ali Farhan, Mohammed Dheyaa Marsool, Mohammed Saad Qasim, Michele Peters, Jose Leal

    Published 2025-01-01
    “…Background: Low-middle income countries harbor the highest burden of cardiovascular diseases globally, but there is an under-representation of these countries in cardiovascular clinical trials. …”
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  6. 5766

    Risk factors for renal insufficiency and survival implications after radical nephrectomy and thrombectomy in renal cell carcinoma with tumor thrombus: a systematic review by Zhigao Huang, Zhuo Liu, Lin Zhuo, Xin Ma, Zhenbin Jiang, Kewei Chen, Jiyuan Chen, Yuxuan Li, Guoliang Wang, Xiaojun Tian, Hongxian Zhang, Lei Liu, Lulin Ma, Kai Hong, Shudong Zhang

    Published 2025-01-01
    “…Abstract Background Renal cell carcinoma (RCC) with venous tumor thrombus (VTT) is great burden over world. Radical nephrectomy (RN) with thrombectomy seems to be its gold standard operation, which might cause reduction of renal function. …”
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  7. 5767

    Prevalence and features of allergic bronchopulmonary aspergillosis, United States, 2016-2022. by Kaitlin Benedict, Jeremy A W Gold, Mitsuru Toda, Joy Hsu

    Published 2025-01-01
    “…Further studies could identify potential barriers to ABPA testing and investigate potential factors affecting payer-related differences in ABPA burden.…”
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  8. 5768

    Development of Virus-Like Particles (VLPs) for Hepatitis C Virus genotype 4: a novel approach for vaccine development in Egypt by Ahmed A. Ali, Rasha A. M. Azouz, Nahla A. Hussein, Reem El-Shenawy, Naiera M. Helmy, Yasmine S. El-Abd, Ashraf A. Tabll

    Published 2025-01-01
    “…Conclusions HCV genotype 4 remains an underexplored target in vaccine development, despite its significant public health burden, especially in Egypt. The successful generation of VLPs for this genotype represents a promising avenue for further vaccine development. …”
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  9. 5769

    Characteristics of exacerbators in the US Bronchiectasis and NTM Research Registry: a cross-sectional study by Nicole C. Lapinel, Radmila Choate, Timothy R. Aksamit, Joseph Feliciano, Kevin L. Winthrop, Andreas Schmid, Sebastian Fucile, Mark L. Metersky

    Published 2024-11-01
    “…Conclusions These findings demonstrate a high disease burden, including increased respiratory symptoms, healthcare resource utilisation, and P.  …”
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  10. 5770

    Maternal Postnatal Psychopathology Predicts Identity Diffusion in Young Adult Offspring by Jens Joas, Justine Hussong, Sena Aktürk, Kirstin Goth, Eva Möhler, Hannah Honecker-Gebauer

    Published 2024-12-01
    “…Linear regression models were used to investigate the amount of explanation of children’s identity diffusion by maternal symptom burden. Results: Maternal psychopathology significantly predicted identity diffusion at all time points with small effect sizes, while after 14 months, the explanation model showed a medium effect size. …”
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  11. 5771

    Using Targeted Virotherapy to Treat a Resistant Ewing Sarcoma Model: From the Bedside to the Bench and Back by Hesham Abdelbary, Christopher W. Brown, Joel Werier, John Bell

    Published 2014-01-01
    “…Our hypothesis is that systemic delivery of VSVΔM51 can demonstrate tumor-specific killing of resistant EWS cells, as well as a significant decrease of tumor burden in EWS bearing mice. Methods. A biopsy sample was obtained from a patient with metastatic EWS and was used to establish a novel EWS cell line. …”
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  12. 5772

    Prevalence, aetiology, and service mapping of dementia in rural Uganda. Part of DEPEND Uganda (Dementia Epidemiology, unmet Need and co-Developing Solutions in Uganda). [version 2;... by Joseph Mugisha, Nicholas J Ashton, Claire J Steves, Racheal Alinaitwe, Josephine Prynn, Tunde Peto, Beatrice Kimono, Martin Prince

    Published 2025-01-01
    “…Crucial risk factors differ in Africa from more intensively studied global areas, including a higher burden of cerebrovascular disease and HIV, but lower rates of other risk factors like physical inactivity. …”
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  13. 5773

    Global disparities in cancer supportive care: An international survey by Alexandre Chan, Lawson Eng, Changchuan Jiang, Mary Dagsi, Yu Ke, Mary Tanay, Cristiane Bergerot, Niharika Dixit, Ana Cardeña Gutiérrez, Ana I. Velazquez, Farhad Islami, Enrique Soto‐Perez‐de‐Celis

    Published 2024-09-01
    “…Abstract Background The global cancer burden is rising, particularly in low‐ and middle‐income countries (LMIC), highlighting a critical research gap in understanding disparities in supportive care access. …”
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  14. 5774

    Cluster randomised controlled trial on the effects of long-term home-based exercise for patients with chronic obstructive pulmonary disease with recent exacerbation: research proto... by Ulla Møller Weinreich, Lars Pilegaard Thomsen, Jane Andreasen, Anna Lei Stoustrup, Thorvaldur S Palsson

    Published 2025-01-01
    “…Background Chronic obstructive pulmonary disease (COPD) is a highly prevalent respiratory disease associated with significant health decline and economic burdens. Pulmonary rehabilitation is an effective intervention, but securing adherence to exercise is difficult, particularly for frail and disabled patients, challenged by leaving their home. …”
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  15. 5775

    Using the Circular Economy to Mitigate the Global Electronic Waste Challenge: A Systematic Literature Review Approach by Mfowabo Maphosa, Vusumuzi Maphosa

    Published 2024-12-01
    “…This systematic literature review evaluates how the knowledge economy and modernisation growth have contributed to the e-waste burden, and how the circular economy can mitigate environmental and health effects. …”
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  16. 5776

    Effects of Pickleball Intervention on the Self-Esteem and Symptoms of Patients with Schizophrenia by Tsai-Chieh Chien, Chao-Chien Chen

    Published 2025-01-01
    “…<i>Background:</i> Schizophrenia is classified by the World Health Organization (WHO) as one of the top ten diseases contributing to the global medical economic burden. Some studies have pointed out that exercise is effective for physical and mental health, as well as cognition. …”
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  17. 5777

    GPR176 Is a Biomarker for Predicting Prognosis and Immune Infiltration in Stomach Adenocarcinoma by Lin Ni, Shuming Chen, Jianyong Liu, He Li, Hu Zhao, Chunhua Zheng, Yawei Zhang, Hancong Huang, Junjie Huang, Bing Wang, Chengzhi Lin

    Published 2023-01-01
    “…Interestingly, GPR176 induced the conversion of TIM while reducing the tumor immune burden (TMB). The expression of GRP176 is closely related to the level of various immunomodulators. …”
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  18. 5778

    Biological and psychosocial factors associated with the persistence of pruritus symptoms: protocol for a prospective, exploratory observational study in Germany (individual project... by Sonja Ständer, Stefan W Schneider, Gudrun Schneider, Stefan Kahnert, Manuel Pedro Pereira, Christian Mess, Volker Huck, Konstantin Agelopoulos, Gina Frank

    Published 2022-07-01
    “…CP has a prevalence of ~20% in the general population and is therefore a significant burden on society, but the transition from acute pruritus to CP is not well understood. …”
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  19. 5779

    Exploring socio-demographic determinants of obesity in Jordanian women of reproductive age: insights from a nationwide survey by Mahmoud Shaaban Abdelgalil, Sara Hosny El-Farargy, Mohamed Adel Dowidar, Mohamed Abd-ElGawad

    Published 2025-01-01
    “…This rising trend, exacerbates the burden of non-communicable diseases and places increasing strain on the healthcare system. …”
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  20. 5780

    Feasibility of integrated, multilevel care for cardiovascular diseases (CVD) and HIV in low- and middle-income countries (LMICs): A scoping review. by Temitope Ojo, Lynette Lester, Juliet Iwelunmor, Joyce Gyamfi, Chisom Obiezu-Umeh, Deborah Onakomaiya, Angela Aifah, Shreya Nagendra, Jumoke Opeyemi, Mofetoluwa Oluwasanmi, Milena Dalton, Ucheoma Nwaozuru, Dorice Vieira, Gbenga Ogedegbe, Bernadette Boden-Albala

    Published 2019-01-01
    “…<h4>Background</h4>Integrated cardiovascular disease (CVD) and HIV (CVD-HIV) care interventions are being adopted to tackle the growing burden of noncommunicable diseases (NCDs) in low-and middle-income countries (LMICs) but there is a paucity of studies on the feasibility of these interventions in LMICs. …”
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