Prevalence, comorbidities, and disease-related complications of rheumatoid arthritis in Colombia: a national cross-sectional study based on administrative claims data by Kevin Maldonado-Cañón, Giancarlo Buitrago, Gerardo Quintana-López

“…Conclusions We describe the first comprehensive assessment of the prevalence patterns of disease-related complications and comorbidities that define the RA burden of disease within a multimorbidity profile. …”
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Role of cumulative biological risk in mediating socioeconomic disparities in cognitive function in the elderly: a mediation analysis by Jimmy Akrivos, Carolyn Wei Zhu, Vahram Haroutunian

“…Of the 4976 elderly (60 years or older) who were selected, 3234 agreed to participate in the household and medical exam interviews (65% response rate).Primary and secondary outcome measures Performance on the Digit Symbol Substitution Test (DSST)—a measure of cognitive function.Results Relative to participants with the lowest level of education or family income, participants who were college graduates (β=24.4, 95% CI 22 to 26.8, p<0.0001) or in the highest income quartile (β=17.3, 95% CI 15.2 to 19.4, p<0.0001) had the highest DSST scores and the least AL burden (β=−0.72, 95% CI −0.98 to −0.47 and β=−0.82, 95% CI −1 to −0.57; p<0.0001, respectively). …”
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Underlying Anticancer Mechanisms and Synergistic Combinations of Phytochemicals with Cancer Chemotherapeutics: Potential Benefits and Risks by Muhammad Ayaz, Asif Nawaz, Sajjad Ahmad, Osama F. Mosa, Alashary Adam Eisa Hamdoon, Modawy Alnour Khalifa, Abdul Sadiq, Farhat Ullah, Abdul Wadood, Atul Kabra, H. C. Ananda Murthy

“…Nevertheless, some of the patients inform their physicians regarding herbal medicine during chemotherapy while others do not, and even most of the patients do not know the composition of herbal medicine they consume during chemotherapy. …”
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Examining associations between oral cancer mortality and economic development of 13 European countries: an ecological and correlational study by Klára Boruzs, Eszter Barbara Bán, Viktor Dombrádi, Gábor Bányai, Gergő József Szőllősi, Klára Bíró

“…The diagnosis, treatment and follow-up of cancer patients are a huge health, economic and social burden for societies. The link between the state of health of a country and its economic performance has been proven by numerous studies. …”
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The impact of chronic kidney disease on developed countries from a health economics perspective: A systematic scoping review. by Sarah Elshahat, Paul Cockwell, Alexander P Maxwell, Matthew Griffin, Timothy O'Brien, Ciaran O'Neill

“…The study has provided a comprehensive updated overview of the burden associated with different CKD stages and renal replacement therapy modalities across developed countries. …”
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Cost-effectiveness of tyrosine kinase inhibitor treatment strategies for chronic myeloid leukemia in South Africa by Rochelle Woudberg, Edina Sinanovic

“…BackgroundThe treatment of chronic myeloid leukemia through tyrosine kinase inhibitors (TKIs) has achieved promising efficacy and safety outcomes, however the costs are associated with a substantial economic burden. The objective of this study was to develop a Markov model with a 20-year time horizon to assess the cost effectiveness of TKIs from a public healthcare system perspective in South Africa.MethodsWe constructed a Markov model to compare three strategies in which treatment was initiated with either imatinib, nilotinib, or dasatinib. …”
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Epidemiological analysis of mental health morbidity in Tamil Nadu by Damodharan Dinakaran, Arpitha Krishna, Aravind Raj Elangovan, Senthil Amudhan, Selvi Muthuswamy, Chellamuthu Ramasubramanian, Palanimuthu T. Sivakumar, Girish N. Rao, Gopalkrishna Gururaj, Mathew Varghese, Vivek Benegal

“…Common mental disorders (depression, anxiety, and substance-use) accounted for most of the morbidity. Conclusion: The burden and treatment gap for mental health morbidity is high in Tamil Nadu. …”
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Navigating the Challenges of Sustainability in the Food Processing Chain: Insights into Energy Interventions to Reduce Footprint by Orlando Corigliano, Pietropaolo Morrone, Angelo Algieri

“…The study delineates the high energy demands and ecological burdens of food production, trade, and consumption through a comprehensive bibliographic analysis of high-impact research papers, authoritative reports, and databases. …”
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Nasopharyngeal carriage of Streptococcus pneumoniae in Latin America and the Caribbean: A systematic review and meta-analysis. by Martín Brizuela, María Carolina Palermo, Tomás Alconada, María Macarena Sandoval, Eugenia Ramirez Wierzbicki, Joaquín Cantos, Paula Gagetti, Agustín Ciapponi, Ariel Bardach, Silvina Ruvinsky

“…<h4>Objectives</h4>To estimate the pneumococcal nasopharyngeal burden in all age groups in Latin America and the Caribbean (LAC) before, during, and after the introduction of pneumococcal vaccine conjugate (PVC).…”
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Nationwide observational study of incidence, management and outcome of spontaneous coronary artery dissection: a report from the Swedish Coronary Angiography and Angioplasty regist... by Per Tornvall, Eva Swahn, Dimitrios Venetsanos, Troels Yndigegn, Sofia Sederholm Lawesson, Lena Jonasson, Nina Johnston, Henrik Wilander, Christos Pagonis, Christian Dworeck, Thomas Kellerth

“…Compared with non-SCAD MI, SCAD patients were younger, with lower cardiovascular risk burden, yet suffered substantial mortality and morbidity and more frequently underwent acute coronary reangiography.…”
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Next-generation diabetes diagnosis and personalized diet-activity management: A hybrid ensemble paradigm. by Muhammad Sajid, Kaleem Razzaq Malik, Ali Haider Khan, Sajid Iqbal, Abdullah A Alaulamie, Qazi Mudassar Ilyas

“…The proposed framework has substantial potential to facilitate early detection, provide tailored dietary guidance, and alleviate the economic burden associated with diabetes-related healthcare expenses.…”
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Relationship between kidney function and healthy life expectancy: A historical cohort study by Hisayuki Ogura, Tadashi Toyama, Hikaru Samuta, Kohei Hirako, Tomoya Itatani, Shiori Nakagawa, Megumi Oshima, Shinji Kitajima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Tomoyuki Takura, Takashi Wada, Yasunori Iwata

“…This study examined associations between CKD and healthy life expectancy, and its economic burden. Methods This study of community-dwelling adults residing in Hakui City, Ishikawa Prefecture, Japan used data from the National Health Insurance database between 2012 and 2022. …”
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The Impact of Atorvastatin on Intraprostatic Biomarkers – Prognostic Value of 3LS-score – Follow-up of ESTO1-Trial by Eemil Lehtonen, Maiju Vertanen, Heimo Syvälä, Teemu Tolonen, Seppo Auriola, Teuvo Tammela, Aino Siltari, Teemu Murtola

“…Background: Prostate cancer (PCa) remains a global health burden, with limited reliable biomarkers beyond prostate-specific antigen (PSA). …”
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Public health programmes to promote mental health in young people: a systematic integrative review protocol by Mihiri Chami Wettasinghe, Nuwan Darshana Wickramasinghe, Tine Van Bortel, Antony Morgan, Antonis A Kousoulis, Nelum Samarutilake, Julie Feiler

“…Introduction In light of the ever-growing mental health disease burden among young people worldwide, we aim to systematically review the global literature to identify the public health programmes targeted at promoting mental health and well-being in young people, the reported/anticipated mental health-related outcomes of the implemented public health programmes and the reported facilitators and barriers in relation to the implementation of those public health programmes.Methods and analysis A comprehensive literature search will be carried out in the following electronic bibliographic databases: MEDLINE, EMBASE, PsycINFO, Scopus, ASSIA, Web of Science, Global Health, AMED, Health Source and The Cochrane Library. …”
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Intravenous thrombolysis prevents neurological deterioration in patients with acute pontine infarction by Zhenxiao Chai, Weili Chen, Yichan Ye, Mengwan Song, Lingling Lin, Dongdong Lin, Xuerong Huang, Lifen Chi, Ruyue Huang

“…The incidence of intracranial hemorrhagic transformation (P = 0.351) and major visceral organ hemorrhage (P = 0.122) was similar in both groups.ConclusionsIVT may prevent early ND after acute pontine infarction without increasing intracranial hemorrhagic transformation, possibly by decreasing the total thrombotic burden.…”
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Comparing diagnostic accuracy of Kato-Katz, Koga agar plate, ether-concentration, and FLOTAC for Schistosoma mansoni and soil-transmitted helminths. by Dominik Glinz, Kigbafori D Silué, Stefanie Knopp, Laurent K Lohourignon, Kouassi P Yao, Peter Steinmann, Laura Rinaldi, Giuseppe Cringoli, Eliézer K N'Goran, Jürg Utzinger

“…<h4>Background</h4>Infections with schistosomes and soil-transmitted helminths exert a considerable yet underappreciated economic and public health burden on afflicted populations. Accurate diagnosis is crucial for patient management, drug efficacy evaluations, and monitoring of large-scale community-based control programs.…”
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“I think people have been in survival mode”: a qualitative study of community connectivity in a neighbourhood of North East England before and during COVID-19 by Mandy Cheetham, Alice Wiseman, Stephen Ward, Sarah Gorman, Fiona Pollard

“…Stakeholders reported that these approaches can help alleviate some of the health, social and financial burdens facing communities that are marginalised. …”
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A new and automated risk prediction of coronary artery disease using clinical endpoints and medical imaging-derived patient-specific insights: protocol for the retrospective GeoCAD... by Louisa Jorm, Daniel Moses, Dona Adikari, Ramtin Gharleghi, Shisheng Zhang, Arcot Sowmya, Sze-Yuan Ooi, Susann Beier

“…The ‘anatomy of risk’ hypothesis recognises that adverse anatomical features of coronary arteries enhance atherogenic haemodynamics, which in turn mediate the localisation and progression of plaques. …”
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Epidemiology and Antimicrobial Resistance of Stenotrophomonas maltophilia in China, 2014–2021 by Hanli Wang, Shirong Li, Haoyu Ji, Yixin Hu, Susheng Zhou, Xingwu Chen, Zhiwei Lu, Qinghai You, Yusheng Cheng, Lei Zha

“…Future research should focus on measuring the true burden of these infections and monitoring the susceptibility of the newly introduced antibiotics, such as cefiderocol.…”
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DIGITAL AND NON-DIGITAL GAMES IN YOUNG LEARNER EFL CLASSROOMS AT WARTIME IN UKRAINE by Ilona Huszti, Enikő Nagy-Kolozsvári, Márta Fábián

“…These games were perceived by YLs as a means offering them to alleviate the burdens of everyday stress while simultaneously facilitating lively and engaging peer interaction in English. …”
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