Impact of pharmacist-prescriber partnerships to track antibiotic prescribing in publicly funded primary care in the Cape Town metropole, South Africa: An implementation study by O Van Hecke, Y Adegoke, M Allwood, K von Pressentin, M Namane, C Butler, M Mendelson, R Coetzee

“…The majority come from socioeconomically disadvantaged communities, and bear the greatest burden from infectious diseases. However, there are very limited published data on and evaluation of antibiotic prescribing linked to clinical indication. …”
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Assessment of awareness of keratoconus and its relation to eye rubbing among Saudi Arabia population by Nuwayyir Abdullah Alqasimi, Lujain Hatim Aljohani, Renato Ambrósio, Renato Ambrósio, Renato Ambrósio, Renato Ambrósio, Renato Ambrósio, Bader Saad AlQahtani, Bader Saad AlQahtani, Nasser Saleh Al Haydar, Bdour Raja Alanazi, Danah Tariq Alfurayhan, Lina Sami Hussain Saber, Fatemah Saleh Alsalem, Nawaf Abdullah Alqahtani, Jose Manuel Vargas

“…Additionally, the study identified several KC risk factors, including but not limited to eye rubbing, allergies, and family history. To alleviate the burden of KC in Saudi Arabia, it is imperative to enhance public health awareness and discourage the habit of eye rubbing.…”
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Forecasting cardiovascular disease mortality using artificial neural networks in Sindh, Pakistan by Moiz Qureshi, Khushboo Ishaq, Muhammad Daniyal, Hasnain Iftikhar, Mohd Ziaur Rehman, S. A. Atif Salar

“…After comparing the results, it was found that the ANNAR model outperformed all the selected models, demonstrating its effectiveness in predicting CVD mortality and quantifying future disease burden in the Sindh province of Pakistan. The study concludes that the ANNAR model is the best-selected model among the competing models for predicting CVD mortality in the Sindh province. …”
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Total Adiponectin Is Inversely Associated with Platelet Activation and CHA2DS2-VASc Score in Anticoagulated Patients with Atrial Fibrillation by Roberto Carnevale, Daniele Pastori, Mariangela Peruzzi, Elena De Falco, Isotta Chimenti, Giuseppe Biondi-Zoccai, Ernesto Greco, Antonino G. M. Marullo, Cristina Nocella, Francesco Violi, Pasquale Pignatelli, Camilla Calvieri, Giacomo Frati

“…Atrial fibrillation (AF) is burdened by enhanced systemic inflammation and platelet activation, as documented by increased blood levels of soluble CD40L (sCD40L). …”
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Italian cultural policy: conclusions for Russia by M. S. Andreykina, D. L. Morozova

“…These are the drive to expand the boundaries and activities associated with the cultural sector, the significant burden on local and regional authorities in the field of cultural heritage preservation, the “quantitative approach” and the application of financial performance indicators to assess cultural organisations performance.The article’s scientific novelty lies in the complex approach to the study of Italian cultural policy using the criteria proposed by D. …”
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Association of quality of life in older patients with breast cancer: a cross-sectional study from China by Xi Chen, Qing Li, Xiang Wang, Lei Ji, Jintao Zhang, Qiao Li, Min Xiao, Shanshan Chen, Pin Zhang, Jiani Wang, Heng Cao, Xiaoyan Qian, Meng Xiu, Zhuoran Li, Yiqun Li, Xiaojuan Zheng

“…Objectives The purpose of this study was to investigate the quality of life (QoL) of older Chinese patients with breast cancer and to explore further the associations of functions, symptoms, financial burdens and comorbidities with global health/quality of life (gQoL).Design This was a cross-sectional study carried out following the Strengthening the Reporting of Observational Studies in Epidemiology checklist.Setting This study was conducted in two hospitals in Beijing from October 2021 to November 2022.Participants Patients with breast cancer aged over 65 years were included in the final analysis, which comprised a total of 481 patients.Primary and secondary outcome measures The European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 and the Charlson Comorbidity Index (CCI) were used to assess patients’ QoL and comorbidities. …”
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Imaging the Brainstem Raphe in Medication-Overuse Headache: Pathophysiological Insights and Implications for Personalized Care by Annika Mall, Christine Klötzer, Luise Bartsch, Johanna Ruhnau, Sebastian Strauß, Robert Fleischmann

“…Comprehensive clinical and psychometric assessments were performed to evaluate headache burden, medication use, and depressive symptoms. TCS was used to assess brainstem raphe echogenicity, with findings analyzed using generalized linear models adjusted for depression. …”
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Role of Chest Radiography in Diagnosing Pulmonary Tuberculosis, Does Every Suspected Case Needs GeneXpert MTB; A Cross-Sectional Study by Mujahid Raza, Saleh Khurshied, Altaf Hussain, Nawal Khurshid, Ali Khurshid

“…CXR is cost effective modality and can help to reduce the burden on health system if smear, culture, or rapid molecular tests are only done in patients where CXR shows suspicion of pulmonary TB. …”
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The Prediction of Necroptosis-Related lncRNAs in Prognosis and Anticancer Therapy of Colorectal Cancer by Hanyu Xiao, Qidan Pang, Yong Wang, Suhe Lai, Hong Chen

“…By analyzing the difference in the tumor microenvironment, microsatellite instability, and tumor mutation burden between the two groups, we explored the potential chemotherapy and immunotherapy drugs. …”
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Clinical and Radiological Outcomes of Corrective Surgery on Adult Spinal Deformity Patients: Comparison of Short and Long Fusion by Koichiro Ono, Kazuo Ohmori, Takeshi Hori

“…Despite the accumulated knowledge of spinal alignment and clinical outcomes the full corrective surgery cannot be applied to all the deformity patients as it requires considerable surgical burden to the patients. The aim of this study was to investigate the clinical and radiological outcomes of the patients who have received short and long fusion for ASD. …”
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Epidemiological analysis of Leishmaniasis prevalence in Pakistan during 2016-2023 by R. Uppal, U. Saeed, M. E. Khattak, A. A. Khan, M. R. Uppal, Z. Z. Piracha, M. N. Khan, D. Shaikh, U. Tariq, A. R. Mahmood, S. S. Ali, B. Muhammad, M. N. Tariq, S. S. Gilani, D. U. Ozsahin, B. Uzun, I. Ozsahin

“…Priority should be given to vulnerable populations and high-burden regions to mitigate leishmaniasis impact in Pakistan.…”
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HIV epidemic in fishing communities in Uganda: A scoping review. by Patou Masika Musumari, Teeranee Techasrivichien, Kriengkrai Srithanaviboonchai, Rhoda K Wanyenze, Joseph K B Matovu, Hemant Poudyal, S Pilar Suguimoto, Saman Zamani, Arunrat Tangmunkongvorakul, Masako Ono-Kihara, Masahiro Kihara

“…The current study describes the status of the HIV burden, prevention, and treatment in Ugandan fishing communities.…”
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Seroprevalence, incidence estimates, and environmental risk factors for dengue, chikungunya, and Zika infection amongst children living in informal urban settlements in Indonesia a... by Joelle I. Rosser, John J. Openshaw, Audrie Lin, Ruzka R. Taruc, Autiko Tela, Nursehang Tamodding, Nurul Pausi Emelia Abdullah, Murni Amiruddin, Esra Buyukcangaz, S. Fiona Barker, Amelia Turagabeci, Ansariadi, Karin Leder, Isra Wahid, on behalf of the RISE Consortium

“…Abstract Background The burden of Aedes aegypti-transmitted viruses such as dengue, chikungunya, and Zika are increasing globally, fueled by urbanization and climate change, with some of the highest current rates of transmission in Asia. …”
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Feasibility and psychometric quality of smartphone administered cognitive ecological momentary assessments in women with metastatic breast cancer by Ashley M Henneghan, Emily W Paolillo, Kathleen M Van Dyk, Oscar Y Franco-Rocha, Soyeong Bang, Rebecca Tasker, Tara Kaufmann, Darren Haywood, Nicolas H Hart, Raeanne C Moore

“…High satisfaction (median 90%), low burden (median 19%), high adherence rates (mean 94%), and 100% retention rate were observed. …”
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Latent Tuberculosis Infections in Different Intensity of Exposure within Moroccan Population: Influence of Age and Bacille Calmette–Guérin Vaccination by Chaimae Kadi, Nouhaila Najimi, Sara El Fakihi, Aicha El Allam, Elmahfoud Akil, Noureddine El Mtili, Rajae El Aouad, Jamaleddine Bourkadi, Fouad Seghrouchni

“…Background: In Morocco, latent tuberculosis infection (LTBI) is a public health concern affected by the country’s location as transit area between sub-Saharan Africa with high TB burden to Europe. This study aimed to assess the influence of exposure intensity to Mycobacterium tuberculosis (Mtb), age, and Bacille Calmette–Guérin (BCG) vaccination on LTBI prevalence in Morocco. …”
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Did the resurgence of childhood lower respiratory infections offset the initial benefit of COVID-19-related non-pharmaceutical interventions in children? A time-series analysis by Inès Fafi, Zein Assad, Léa Lenglart, Zaba Valtuille, Florentia Kaguelidou, Camille Aupiais, Aurélie Bourmaud, Alexis Rybak, Stéphane Bechet, Corinne Levy, Robert Cohen, Bruno Frandji, Andreas Werner, François Angoulvant, Romain Basmaci, Naïm Ouldali

“…The implementation of some societally acceptable NPI, particularly during epidemics, may be considered in the future to further reduce the burden of paediatric LRTI.…”
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Protocol for a prospective observational cohort study of cutaneous leishmaniasis in Ethiopia [version 2; peer review: 2 approved, 1 approved with reservations] by Fewzia Shikur Mohammed, Amel Beshir Mohammed, Shimelis Doni Nigusse, Feleke Tilahun Zewdu, Abebaw Yeshambel Alemu, Teklu Cherkose, Kidist Bobosha, Eshetu Molla, Iris Mosweu, Vanessa Yardley, Saba Maria Lambert, Mirgissa Kaba, Endalamaw Gadisa, Yohannes Hailemichael, Catherine Pitt, Elizabeth Allen, Stephen L. Walker, Michael Marks

“…Aim The overall aim of this study is to improve the understanding of the health and economic burden of CL. Methods We have designed an observational, multi-centre cohort study to examine treatment outcomes for CL in Ethiopia which includes clinical outcomes, laboratory outcomes, patient reported outcome measures, scar assessments and cost effectiveness. …”
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Exploring the link between Multimorbidity and direct healthcare costs in Ireland: A cross-sectional study by Sharon Walsh, Paddy Gillespie

“…Background Multimorbidity has emerged as a major challenge facing health services globally, which will place a substantial burden on health systems going forward. This paper seeks to estimate the association between multimorbidity and direct healthcare costs among older people in Ireland from a healthcare system perspective. …”
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ANALYSIS OF RAT PLATELET COUNT AFTER ELECTRICAL EXPOSURE IN ACUTE AND SUBACUTE PHASE OF BURN INJURY by Fransiska Nooril F P H, Ulfa Elfiah, Laksmi Indreswari, Desie Dwi Wisudanti

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A pan-immune panorama of bacterial pneumonia revealed by a large-scale single-cell transcriptome atlas by Kun Xiao, Yan Cao, Zhihai Han, Yuxiang Zhang, Laurence Don Wai Luu, Liang Chen, Peng Yan, Wei Chen, Jiaxing Wang, Ying Liang, Xin Shi, Xiuli Wang, Fan Wang, Ye Hu, Zhengjun Wen, Yong Chen, Yuwei Yang, Haotian Yu, Lixin Xie, Yi Wang

“…Abstract Bacterial pneumonia is a significant public health burden, contributing to substantial morbidity, mortality, and healthcare costs. …”
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