Showing 3,041 - 3,060 results of 3,238 for search 'Journal of Clinical Investigation', query time: 0.12s Refine Results
  1. 3041
  2. 3042
  3. 3043

    Diagnostic accuracy of CCTA-derived versus angiography-derived quantitative flow ratio (CAREER) study: a prospective study protocol by Liang Zhang, Yang Chen, Cheng Li, Ming Li, Shaofeng Guan, Xinkai Qu, Tingwen Weng, Qian Gan, Zehang Li, Wenzheng Han, Xinrong Zhai, Lin Qi, Xifeng Chang, Shengxian Tu

    Published 2022-06-01
    “…The objective of this investigator-initiated, prospective, single-centre clinical trial is to evaluate the diagnostic performance of CT-QFR with respect to angiography-derived QFR, using FFR as the reference standard.Methods and analysis A total of 216 patients who have at least one lesion with a diameter stenosis of 30%–90% in an artery with ≥2.0 mm reference diameter will be enrolled in the study. …”
    Get full text
    Article
  4. 3044
  5. 3045
  6. 3046
  7. 3047
  8. 3048
  9. 3049

    How many stroke survivors develop problematic spasticity requiring pharmacological therapy? An international (Europe and USA) observational study protocol by Pascal Maisonobe, Sergiu Groppa, Simon Page, Richard D Zorowitz, Laura Serrano Barrenechea, Simon Butet, David Hernández Herrero, Rama Prasad, Susan Sandars, Seema Meloni, Alessandro Picelli

    Published 2025-01-01
    “…Results will be published at international meetings and in an international peer-reviewed journal. Lay summaries will be prepared to accompany the primary paper and will also be provided to study participants.Trial registration number ClinicalTrials.gov NCT06055725.…”
    Get full text
    Article
  10. 3050
  11. 3051
  12. 3052

    Effect of maternal cigarette smoking and alcohol consumption during pregnancy on birth weight and cardiometabolic risk factors in infants, children and adolescents: a systematic re... by Eunice Bolanle Turawa, Tammy Charlene Hartel, André Oelofse, Juléy Janice Abigail De Smidt

    Published 2022-07-01
    “…Therefore, this review aims to provide a summary of the most recent evidence on birth outcomes and cardiometabolic risk in children associated with alcohol and/or tobacco exposure in utero.Methods and analysis PubMed, Scopus and Web of Science will be searched to identify published articles from 1 January 2001. Clinical studies that investigate the association between maternal cigarette smoking or alcohol consumption and birth weight and cardiometabolic risk factors in infants, children and adolescents will be included. …”
    Get full text
    Article
  13. 3053
  14. 3054

    Efficacy and safety of perioperative analgesia in PENG block for children undergoing hip surgery with developmental dysplasia: study protocol for a randomized, double-blinded, non-... by Mingzhe Xu, Yi He, Zhi Li, Bin Du

    Published 2025-01-01
    “…All data will be collected by blinded investigators. The trial’s final results will be published in a peer-reviewed scientific journal. …”
    Get full text
    Article
  15. 3055
  16. 3056
  17. 3057

    Levosimendan and Global Longitudinal Strain Assessment in Sepsis (GLASSES 1): a study protocol for an observational study by Iacopo Cappellini, Alessandra Melai, Lucia Zamidei, Maddalena Parise, Simone Cipani, Guglielmo Consales

    Published 2020-09-01
    “…The primary endpoint is recovery of GLS ≥15% and the secondary endpoint is a relative reduction in mortality of 15%.Ethics and dissemination The investigators declare that the study will be conducted in full compliance with international regulations (EU Directive 2016/679/EC) and national implementation (DM 15 July 1997; 211/2003; 200/2007) regarding the clinical trial and the principles of the Declaration of Helsinki. …”
    Get full text
    Article
  18. 3058
  19. 3059

    Protocol for project recovery after cardiac surgery: a single-center cohort study leveraging digital platform to characterise longitudinal patient-reported postoperative recovery p... by Harlan M Krumholz, Erica Spatz, Sanket S Dhruva, Yawei Zhang, Makoto Mori, Cornell Brooks, Bobak J Mortazavi, George C Linderman, Lawrence A Grab, Arnar Geirsson, Sarwat I Chaudhry

    Published 2020-09-01
    “…We are using a health-information exchange platform to collect patient-reported outcome measures (PROMs) and wearable device data to phenotype recovery patterns in the 30-day period after cardiac surgery hospital discharge, to identify factors associated with these phenotypes and to investigate phenotype associations with clinical outcomes.Methods and analysis We designed a prospective cohort study to enrol 200 patients undergoing valve, coronary artery bypass graft or aortic surgery at a tertiary centre in the USA. …”
    Get full text
    Article
  20. 3060