The Differential Expressions and Associations of Intracellular and Extracellular GRP78/Bip with Disease Activity and Progression in Rheumatoid Arthritis by Guoyin Liu, Jianping Wu, Yongqiang Wang, Yuansheng Xu, Chun Xu, Guilin Fang, Xin Li, Jianmin Chen

“…Patients with RA, osteoarthritis (OA), and traumatic meniscal injury (TMI) without radiographic OA were consecutively recruited for the study. …”
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Impact of Flexor Tendon Traction Tenolysis on Clinical Outcomes in Open A1 Pulley Release for Trigger Finger by Shalimar Abdullah, BMBS, MS, Syed Jeffrey Syed Ahmad Kabeer, MBChB, MD, Lim Chia Hua, MD, Jamari Sapuan, MD, MS, Parminder Singh Gill, MBBS, MS, Elaine Soh Zi Fan, MBBS, MD

“…Outcomes assessed include finger range of motion, hand function (Disabilities of the Arm, Shoulder, and Hand [QuickDASH] score), complications (eg, digital nerve injury, superficial infection, and residual trigger finger), and surgery duration. …”
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Associated adverse outcomes with tumor treating fields when combined to temozolomide versus temozolomide alone for the treatment of glioblastoma: a meta-analysis of randomized tria... by Yuanyuan Chen, Yan Chen, Hong Zhen, Danhua Lou

“…Results of this analysis showed that TTF in combination with temozolomide was not associated with significantly higher adverse outcomes related to blood and lymphatic system disorders (RR:0.87, 95% CI 0.30–2.48; P = 0.79), gastrointestinal disorders (RR: 0.83, 95% CI 0.14–4.72; P = 0.83), general deterioration and malaise (RR: 1.43, 95% CI 0.90–2.25; P = 0.13), infections and infestations (RR: 1.21, 95% CI 0.33–4.45; P = 0.78), injury/poison and procedural complications (RR: 1.78, 95% CI 0.88–3.61; P = 0.11), metabolic and nutritional disorders (RR: 0.61, 95% CI 0.34–1.08; P = 0.09), central nervous system disorders (RR: 1.14, 95% CI 0.89–1.46; P = 0.31), musculoskeletal and connective tissue disorders (RR: 0.99, 95% CI 0.48–2.07; P = 0.99), respiratory/thoracic/mediastinal disorders (RR: 0.85, 95% CI 0.44–1.62; P = 0.62), and psychiatric disorders (RR: 1.27, 95% CI 0.42–3.79; P = 0.67). …”
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Comparative study of arthroscopic autologous cancellous bone grafting and medial malleolar osteotomy combined with autologous periosteal iliac bone grafting for the treatment of os... by Xinyu Tang, Xinkun Han, Haitao Fu, Youliang Shen, Dongfang Zhang, Qinwei Guo, Chao Qi

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EpCare: Prototipe Sistem Detektor Pre-Iktal Pasien Epilepsi Berbasis Fitur CSI dari Sinyal EKG 1 Kanal Menggunakan AD8232 by Diah P. Wulandari, Arief Kurniawan, Alvin Nathanael, Santi W. Purnami, Anda L. Juniani, Wardah R. Islamiyah

“…Abstract Epileptic seizures may occur at anytime and anywhere, and in certain conditions may lead to fatal injury. Therefore, the need for wearable device that can alert user to an impending seizure is important. …”
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Regulation of LPS-Induced Inflammatory Responses in Bovine Mammary Epithelial Cells via TLR4-Mediated NF-κB and MAPK Signaling Pathways by Lactoferrin by Kai Zhang, Ruizhen Zhang, Yuanyuan Zhang, Min Zhang, Hong Su, Feifei Zhao, Daqing Wang, Guifang Cao, Yong Zhang

“…This study used bovine mammary epithelial cells (BMECs) cultured in vitro as the research model. An inflammatory injury model was established by stimulating BMECs with LPS to investigate whether LF at different concentrations (10, 50, 100, and 200 μg·mL⁻¹) could inhibit the inflammatory response before and after the onset of inflammation. …”
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Risk Factors and Outcome of Sepsis in Traumatic Patients and Pathogen Detection Using Metagenomic Next-Generation Sequencing by Yiqing Tong, Jianming Zhang, Yimu Fu, Xingxing He, Qiming Feng

“…The sepsis group and non-sepsis group exhibited significant differences regarding shock on admission, blood transfusion, mechanical ventilation, body temperature, heart rate, WBC count, neutrophil count, hematocrit, urea nitrogen, creatinine, CRP, D-D dimer, PCT, scores of APACHE II, sequential organ failure assessment (SOFA), and Injury Severity Score (ISS) on admission to the EICU, and Multiple Organ Dysfunction Syndromes (MODS) (P<0.05). …”
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Establishing an Electrophysiological Recording Platform for Epidural Spinal Cord Stimulation in Neuropathic Pain Rats by Yang CT, Shyu BC, Lin WT, Lu KH, Lin CR, Wen YR, Chen CC

“…This study comprehensively analyzed methodology and technical challenges and pitfalls encountered during the development and implementation of this model.Materials and Methods: Employing a newly developed pUHF-SCS (± 3 V, 2 Hz pulses with 500-kHz biphasic radiofrequency sinewaves), we assessed analgesic effect and changes of evoked local field potentials (eLFPs) in the bilateral primary somatosensory and anterior cingulate cortices in the rats with or without spared nerve injury (SNI) using the platform. The placement of stimulating needle electrodes in the hind paw was examined and optimized for functionality.Results: SNI enhanced the C component of eLFPs in bilateral cortexes elicited by stimulating the contralateral but not the ipsilateral lateral aspect of the hind paw. …”
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Development and Validation of Risk Stratification for Heart Failure After Acute Coronary Syndrome Based on Dynamic S100A8/A9 Levels by Jie Ma, Ke Ma, Jing Chen, Xinying Yang, Fei Gao, Hai Gao, Hui Zhang, Xin‐Liang Ma, Jie Du, Ping Li, Yulin Li

“…S100A8/A9 is not only rapidly released after myocardial ischemia, but is also involved in reperfusion injury, which is an important predictor of HF after ACS. …”
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Exosomes Derived from Mesenchymal Stem Cells Ameliorate Hypoxia/Reoxygenation-Injured ECs via Transferring MicroRNA-126 by Qunwen Pan, Yan Wang, Qing Lan, Weiquan Wu, Zhenxuan Li, Xiaotang Ma, Liming Yu

“…Mesenchymal stem cells (MSCs) show protective effects on ischemia/reperfusion- (I/R-) induced endothelial cell (EC) injury and vascular damage. Stem cell-released exosomes (EXs) could modulate target cell functions by delivering their cargos, and exert therapeutic effects as their mother cells. miR-126 is an important regulator of EC functions and angiogenesis. …”
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Spinally targeted paired associative stimulation with high-frequency peripheral component induces spinal level plasticity in healthy subjects by Anna Nätkynmäki, Leena Lauronen, Piia Haakana, Erika Kirveskari, Janne Avela, Anastasia Shulga

“…Abstract A novel variant of paired-associative stimulation (PAS) consisting of high-frequency peripheral nerve stimulation (PNS) and high-intensity transcranial magnetic stimulation (TMS) above the motor cortex, called high-PAS, can lead to improved motor function in patients with incomplete spinal cord injury. In PAS, the interstimulus interval (ISI) between the PNS and TMS pulses plays a significant role in the location of the intended effect of the induced plastic changes. …”
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Patent Ductus Arteriosus Stenting via Percutaneous Common Carotid Artery Access for Ductus Dependent Pulmonary Blood Flow in Newborns and Infants: Experience in Latvia by Zanda Grīnberga, Elizabete Zaharāne, Pauls Sīlis, Valts Ozoliņš, Normunds Sikora, Elīna Ligere

“…Carotid access for newborn cardiac catheterisation avoids femoral arterial injury and improves the catheter course for certain transvasal procedures. …”
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The Genealogy of Šemetas' in 15th-16th century by Saulė Viskantaitė-Saviščevienė

“…At first, Stanislovas, the brother of Merkelis, was vice-prefect of Telšiai, and after that, he became the governor of Pajūris. Eventually, he occupied the office of the GDL as a kuchmistrz (Lat. magister coquille).   …”
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Perbandingan Nilai Apgar antara Persalinan Normal dengan Seksio Sesarea Elektif by Neila Azka, Syahredi ., Eva Chundrayetti

“…Several factor are contributing, such as fears of injury to the fetus, increased women's request to do a cesarean section deliveries and socioeconomic factors. …”
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Use of Go-Beyond as a Self-Directed Internet-Based Program Supporting Veterans’ Transition to Civilian Life: Preliminary Usability Study by Karolina Katarzyna Alichniewicz, Sarah Hampton, Madeline Romaniuk, Darcy Bennett, Camila Guindalini

“…Mental health issues, physical injuries, difficulties in relationships, and identity loss compound the reintegration process. …”
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April 15th war and hemodialysis patients in Sudan: a cross-sectional study by Malaz Hassan Dafaalla Idrees, Moez Mohammed Ibrahim Bashir, Balqees Abdeen Ahmed Mohamed, Amal Essam Ali Ahmed, Hamid Mohieldin Mohamed Abdalla, Kamil Mirghani Ali Shaaban

“…Hemodialysis patients are among the most affected by this war’s aftermath, which ranges from obvious dangers like violence-related injuries and deaths to more indirect effects like the suspension of access to preventive and curative medical care. …”
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Noninvasive Assessment of Liver Fibrosis in Patients with Chronic Hepatitis B or C by Contrast-Enhanced Magnetic Resonance Imaging by René Hako, Pavol Kristian, Peter Jarčuška, Ivana Haková, Ivana Hockicková, Ivan Schréter, Martin Janičko

“…The first group (n=19) was a control group of healthy individuals without liver injury and remaining 59 subjects were chronic hepatitis B and C patients who underwent liver biopsy. …”
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Psychological peculiarities of professional development in late adulthood by E. F. Zeer, E. E. Symanyuk, A. A. Ryabukhina, G. I. Borisov

“…The data obtained are important for developing a strategy of professional development in late adulthood, which will allow for determining the methods of the psychological support of employees, the improvement of productivity and the reduction of occupational injuries. Based on the specifics of motivation of professional activity in late adulthood and the characteristics of quality of life, the relevant programmes can be developed to overcome the professional loss crisis.…”
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Exosome miR-199a-5p modulated vascular remodeling and inflammatory infiltration of Takayasu’s arteritis by Shuning Guo, Jiehan Li, Shurui Pang, Jing Li, Xinping Tian

“…Moreover, exosome miR-199a-5p and MMP2 derived from serum possess potential as future biomarkers for vascular injury.…”
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Booster Vaccination against Yellow Fever in Gambian children-(BoVY) -a Phase 3 clinical trial to establish safety and immunogenicity of repeated YF vaccination in healthy Gambian c... by David Jeffries, Caitlin Pley, Beate Kampmann, Mam Nabou Leigh, Julia Strandmark, Ed Clarke, Peter Ndow, Ebrima Kanteh, Amadou Faal, Elishia Roberts

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