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6041
Transcutaneous vagus nerve stimulation as a pain modulator in knee osteoarthritis: a randomized controlled clinical trial
Published 2025-01-01“…We used a variety of outcome measures, including the visual analog scale (VAS), pressure pain threshold (PPT), knee injury and osteoarthritis outcome score (KOOS), PainDETECT (PD-Q) and Douleur Neuropathique 4 (DN4) questionnaires. …”
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6042
Methyltransferase-like 7B participates in bladder cancer via ACSL3 m6A modification in a ferroptosis manner
Published 2025-01-01“…We, here, examined that ectopic METTL7B expression abolished ferroptosis markers in cells raised by Erastin treatment, including the production of lipid ROS, the increased cellular iron and MDA content, the decreased gene expression of ACSL3, FANCD2, and FADS2, as well as the mitochondrial injury observed by electron microscopy. Mechanically, ectopic METTL7B expression promoted m6A modification on ACSL3 mRNA. …”
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6043
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6044
Staphylococcus aureus vesicles impair cutaneous wound healing through p38 MAPK-MerTK cleavage-mediated inhibition of macrophage efferocytosis
Published 2025-01-01“…Targeting this pathway could open up a new therapeutic avenue facilitating the treatment of chronic, non-healing skin injuries.…”
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6045
Hubungan Tingkat Keteraturan Berolahraga Terhadap Komplikasi Penyakit pada Pasien DM Tipe 2 di Poliklinik Endokrin RSUP DR. M. Djamil Padang
Published 2016-08-01“…It </em><em> c</em><em>ould be the cause of</em><em> </em><em> micovascular and macrovascular injuries. Exercise regularity can lead blood glucose toward normal. …”
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6046
Circular RNA encoded by PPARG in the peripheral blood and a lipopolysaccharide-induced cardiomyocyte inflammation model is identified as a marker of fulminant myocarditis
Published 2025-02-01“…Circular RNAs (circRNAs) are highly stable in peripheral blood due to their special closed-loop structure, and reports have described their involvement in regulating inflammatory responses and cell injury in cardiomyocytes. This study attempted to identify the abnormal expression of circRNAs in the peripheral blood of patients with FM and to evaluate the potential diagnostic value. …”
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6047
Comprehensive approach to predictive analysis and anomaly detection for road crash fatalities
Published 2025-01-01“…Since traffic accidents are a major global cause of injury and death, it is essential to comprehend and reduce their effects. …”
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6048
Association of liver biopsy pathology on outcome of patients undergoing heart transplantation
Published 2025-02-01“…Lay summary: This study found that the presence of advanced liver injury did not confer a difference in the waitlist and post heart transplant (HT) survival rates of patients on the HT transplant list. …”
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6049
Effect of soluble dietary fiber extracted from Lentinula edodes (Berk.) Pegler on lipid metabolism and liver protection in mice on high-fat diet
Published 2025-01-01“…It is proved that the soluble dietary fiber of Lentinus edodes can alleviate the organ fat accumulation caused by high-fat diet to some extent, effectively combat the liver injury, oxidative stress pressure and lipid metabolism disorder caused by high-fat diet, and provide an experimental basis for the subsequent effective use of soluble dietary fiber of Lentinus edodes in fat reduction.…”
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6050
Does binge drinking between the age of 18 and 25 years predict alcohol dependence in adulthood? A retrospective case–control study in France
Published 2019-05-01“…Prevention measures for binge drinking during preadulthood, especially frequent binge drinking, should be implemented to prevent acute consequences as injury and death and long-term consequences as alcohol dependence.Trial registration number NCT03204214; Results.…”
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6051
Association Between GABRG2 and Self-Rating of the Effects of Alcohol in a French Young Adult Sample
Published 2025-01-01“…Box 104, Brumunddal, 2381, Norway, Email jenny.s.moe@uit.noPurpose: Alcohol use is a leading risk factor for preventable death, injury, and disease globally. Low sensitivity to the effects of alcohol is influenced by genes and predicts risk for harmful alcohol use and alcohol use disorder (AUD). …”
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6052
Beeswax Alcohol (BWA, Raydel<sup>®</sup>) Improved Blood Oxidative Variables and Ameliorated Severe Damage of Zebrafish Kidneys, Testes, and Ovaries Impaired by 24-Week Consumption...
Published 2024-12-01“…Objectives: The present study describes the comparative effect of 24-week supplementation of beeswax alcohol (BWA, Raydel<sup>®</sup>, 0.5% and 1.0%, wt/wt) and coenzyme Q<sub>10</sub> (CoQ<sub>10</sub>, 0.5% and 1.0%, wt/wt) on plasma oxidative variables and the prevention of organ injury in adult zebrafish subjected to a high-cholesterol (HC, 4%, wt/wt) and -D-galactose (Gal, 30%, wt/wt) diet. …”
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6053
The clinical application and anatomical analysis of proximal peroneal artery perforator in free fibula flap based on CTA
Published 2025-01-01“…In scenarios where the distal peroneal perforator is absent or suffers intraoperative injury, the proximal peroneal perforator can serve as a reliable alternative for preparing a free fibula osteal flap combined with a proximal peroneal perforator skin paddle.…”
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6054
The Impact of Complete Revascularization in Symptomatic Severe Left Ventricular Dysfunction between Coronary Artery Bypass Graft and Percutaneous Coronary Intervention
Published 2023-01-01“…There was no significant difference in the incidence values of in-hospital course and those of in-hospital mortality, acute kidney injury, and postprocedural hemodialysis. There was no significant difference in the 1-yearfollow-up of recurrent MI, revascularization, or stroke between the groups. …”
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6055
A Data-Driven Deep Learning Framework for Prediction of Traffic Crashes at Road Intersections
Published 2025-01-01“…We argue that TCP for roads, especially for crashes at or near road intersections which account for more than 50% of the fatal or injury crashes based on the Federal Highway Administration, has a significant practical and research value and thus deserves more research. …”
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6056
Creatinine- and Cystatin C-Based Incidence of Chronic Kidney Disease and Acute Kidney Disease in AKI Survivors
Published 2018-01-01“…Renal dysfunction after acute kidney injury (AKI) is common, potentially modifiable, but poorly understood. …”
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6057
Nd:YAG Laser Vitreolysis for Symptomatic Vitreous Floaters: Application of Infrared Fundus Photography in Assessing the Treatment Efficacy
Published 2019-01-01“…No severe Nd:YAG vitreolysis procedure-related complications occurred in all patients except one mild retinal injury. There were no significant changes in intraocular pressure and visual acuity after the laser treatment. 43 eyes had improved symptoms; in 8, floaters had disappeared; and 4 had no changes according to VFQ-25 scores. …”
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6058
Argonaute2 and Argonaute4 Involved in the Pathogenesis of Kawasaki Disease via mRNA Expression Profiles
Published 2025-01-01“…(<i>p</i> > 0.05) Conclusion: Endothelial cell inflammation and injury, two basic pathological mechanisms, are thought to be involved in coronary endothelial dysfunction in KD. …”
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6059
Metagenomic Sequencing Combined with Metabolomics to Explore Gut Microbiota and Metabolic Changes in Mice with Acute Myocardial Infarction and the Potential Mechanism of Allicin
Published 2025-02-01“…Moreover, Spearman correlation analysis suggested a significant association between the allicin-induced alterations in microbiota and metabolites with cardiac function and inflammatory cytokines.Conclusion: Our study demonstrated that allicin alleviated myocardial injury and reduced inflammatory response by inhibiting the NF-κB-mediated NLRP3/Caspase-1/GSDMD pathway while remodeling microbiota disturbance, improving serum metabolic disorder, and enhancing the intestinal barrier. …”
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6060
Public insight into knee osteoarthritis: a cross-sectional study from the West Bank, Palestine
Published 2025-02-01“…The majority identified high BMI (87%, n = 632), advancing age (94%, n = 683), and previous knee injury (72%, n = 520) as risk factors, although only 42% (n = 306) acknowledged genetics as one. …”
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