Functional Connectivity and MRI Radiomics Biomarkers of Cognitive and Brain Reserve in Post-Stroke Cognitive Impairment Prediction—A Study Protocol by Hanna Maria Dragoș, Adina Stan, Livia Livinț Popa, Roxana Pintican, Diana Feier, Nicu Cătălin Drăghici, Dragoș-Cătălin Jianu, Diana Chira, Ștefan Strilciuc, Dafin F. Mureșanu

“…While the mechanisms behind PSCI are not fully understood, the brain and cognitive reserve concepts are topics of ongoing research exploring the ability of individuals to maintain intact cognitive performance despite ischemic injuries. Brain reserve refers to the brain’s structural capacity to compensate for damage, with markers like hippocampal atrophy and white matter lesions indicating reduced reserve. …”
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A Survey of the Knowledge, Attitudes and Practices of a Sample of Albanian Medical Students in Relation to Occupational Exposure to Biological Agents by Lorenzo Ippoliti, Luca Coppeta, Ersilia Buonomo, Giuseppina Somma, Giuseppe Bizzarro, Cristiana Ferrari, Andrea Mazza, Agostino Paolino, Claudia Salvi, Vittorio Caputi, Antonio Pietroiusti, Andrea Magrini

“…Healthcare workers (HCWs), including hospital-based medical students, face high and often under-reported rates of exposure to needlestick and sharps injuries. Previous studies have shown that students’ knowledge of infection control varies, highlighting the importance of pre-placement training. …”
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Ginsenoside Rg1: A bioactive therapeutic agent for diverse liver diseases by Mingyu Wu, Ke Li, Jiabin Wu, Xianyi Ding, Xiaotong Ma, Wenhong Wang, Weihua Xiao

“…To delay the transition from benign tissue lesions to a substantial organ injury, scientists have gradually applied natural compounds derived from plants as a complementary therapy in the field of hepatology. …”
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Cigarette and e-cigarette reversely regulated autophagy via distinct level of ROS in vitro by Yao Wang, Jialing Zhong, Zuyi Jin, An Luo, Zehong Wu, Xingtao Jiang, Jianwen Chen, Peiqing Liu, Min Li

“…This study aimed to compare the cytotoxicity of conventional cigarettes and e-cigarettes, identify the toxic components of e-cigarettes, and explore the mechanisms of cellular injury. In this study, the conventional cigarette and seven flavored e-cigarettes, along with their constituents, including solvents, nicotine, and seven flavoring agents were tested. …”
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Potentiality of algorithms and artificial intelligence adoption to improve medication management in primary care: a systematic review by Gianfranco Damiani, Antonio Oliva, Gerardo Altamura, Massimo Zedda, Mario Cesare Nurchis, Giovanni Aulino, Aurora Heidar Alizadeh, Francesca Cazzato, Gabriele Della Morte, Matteo Caputo, Simone Grassi, Maria Teresa Riccardi, Martina Sapienza, Giorgio Sessa

“…Specifically, the Population chosen was general population of all ages (ie, including paediatric patients) in primary care settings (ie, home setting, ambulatory and nursery homes); the Intervention considered was the analysis AI and/or algorithms (ie, intelligent programs or software) application in primary care for reducing medications errors, the Comparator was the general practice and, lastly, the Outcome was the reduction of preventable medication errors (eg, overprescribing, inappropriate medication, drug interaction, risk of injury, dosing errors or in an increase in adherence to therapy). …”
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Mirizzi Syndrome: Diagnosis and Management of a Challenging Biliary Disease by Gennaro Clemente, Andrea Tringali, Agostino M. De Rose, Elena Panettieri, Marino Murazio, Gennaro Nuzzo, Felice Giuliante

“…Furthermore, it increases the risk of intraoperative biliary injury during cholecystectomy. The aim of this study is to point out some particular aspects of diagnosis and treatment of this condition. …”
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Design, synthesis and biological evaluation of buthutin derivatives as cardioprotective agents by Yuan Liu, Fa-Qi Wang, Xin-Hao Hua, Shu-Han Yang, Li-Ning Wang, Yun-Sheng Xu, Chen-Yue Shao, Xiang-Bo Gou, Yu-Ming Liu

“…In this study, twenty-nine buthutin derivatives were designed, synthesized, and evaluated for their NHE-1 inhibition and protective effects on cardiomyocyte injury. The structure of the newly synthesized compounds had been confirmed by 1H-NMR, 13C-NMR, and HR-ESI-MS spectra. …”
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Immune system effectors as biomarkers of prognosis after acute burns in a case-control study by Alejandro Ferrari, Lorena Di Croce, Sabrina Saavedra, Marisel Hartwig, Omar Perrone, María Alejandra Guzmán

“…Following the initial injury, it has been demonstrated that the immune system plays a key role in early inflammation, tissue regeneration, and the response against pathogens. …”
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Regeneration of Rabbit Auricular Cartilage After the Intravenous Stem Cell Injection by Pavlo Virych, Nadiia Shuvalova, Anton Karas, Galina Karas, Svitlana Chaika, Tetiana Kucherenko, Ganna Minina, Marina Timchenko, Oleg Melnykov, Yurii Minin

“…Tissue samples from the site of the injury were collected after 1, 2, and 3 months. Histological examinations of the tissues were carried out after staining with fuchsin-eosin, azure II–eosin, and according to Weigert. …”
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Telephone coaching supports exercise in people with prediabetes and diabetes: A mixed-methods study by Ana Paula Delgado Bomtempo, Gabriela Lima de Melo Ghisi, Mariana Balbi Seixas, Adriano Luiz Pereira, Paul Oh, Danielle Aparecida Gomes Pereira, Lilian Pinto da Silva

“…The most frequently reported barriers to exercise were weather, pain or physical injuries, and lack of adequate space. The average self-reported time exercising was higher than 150 minutes/week in all phone calls. …”
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Cytokines TNF-α, IL-6, IL-17F, and IL-4 Differentially Affect Osteogenic Differentiation of Human Adipose Stem Cells by Angela P. Bastidas-Coral, Astrid D. Bakker, Behrouz Zandieh-Doulabi, Cornelis J. Kleverlaan, Nathalie Bravenboer, Tim Forouzanfar, Jenneke Klein-Nulend

“…During the initial stages of bone repair, proinflammatory cytokines are released within the injury site, quickly followed by a shift to anti-inflammatory cytokines. …”
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Mechanisms Predisposing Penile Fracture and Long-Term Outcomes on Erectile and Voiding Functions by Leonardo O. Reis, Marcelo Cartapatti, Rafael Marmiroli, Eduardo Jeronimo de Oliveira Júnior, Ricardo Destro Saade, Adriano Fregonesi

“…Six (14.3%) patients had urethral injury and two (4.8%) had erectile dysfunction, treated by penile prosthesis and PDE-5i. …”
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Serum Levels of IL-33 and Correlation with IL-4, IL-17A, and Hypergammaglobulinemia in Patients with Autoimmune Hepatitis by Ma Liang, Zhang Liwen, Zhuang Yun, Ding Yanbo, Chen Jianping

“…Additionally, the serum levels of IL-33 in AIH patients were correlated positively with markers of hypergammaglobulinemia (IgG, IgM, and IgA) and liver injury (γ-GT/ALP). Also, the serum levels of IL-33 in AIH patients were correlated positively with proinflammatory cytokine levels (IL-17A and IL-4). …”
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Outcomes of anterior cruciate ligament reconstruction surgery from private and public healthcare services in AustraliaKey points by Thomas J. West, Andrea M. Bruder, Kay M. Crossley, Michael A. Girdwood, Laura K. To, Jamon L. Couch, Mark J. Scholes, Sebastian C.S. Evans, Melissa J. Haberfield, Christian J. Barton, Ewa M. Roos, Alysha De Livera, Adam G. Culvenor

“…Multivariable linear regression assessed the association between healthcare service used (private versus public) with self-reported outcomes (Knee injury and Osteoarthritis Outcome Score (KOOS) subscales of pain, symptoms, sport/recreation, knee-related quality of life (QoL); 0–100 scale), adjusting for potential confounders. …”
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Strategies to Improve the Quality and Freshness of Human Bone Marrow-Derived Mesenchymal Stem Cells for Neurological Diseases by Da Yeon Lee, Sung Eun Lee, Do Hyeon Kwon, Saraswathy Nithiyanandam, Mi Ha Lee, Ji Su Hwang, Shaherin Basith, Jung Hwan Ahn, Tae Hwan Shin, Gwang Lee

“…Human bone marrow-derived mesenchymal stem cells (hBM-MSCs) have been studied for their application to manage various neurological diseases, owing to their anti-inflammatory, immunomodulatory, paracrine, and antiapoptotic ability, as well as their homing capacity to specific regions of brain injury. Among mesenchymal stem cells, such as BM-MSCs, adipose-derived MSCs, and umbilical cord MSCs, BM-MSCs have many merits as cell therapeutic agents based on their widespread availability and relatively easy attainability and in vitro handling. …”
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YKL-40 as a Novel Factor Associated with Inflammation and Catabolic Mechanisms in Osteoarthritic Joints by Tuija Väänänen, Anna Koskinen, Erja-Leena Paukkeri, Mari Hämäläinen, Teemu Moilanen, Eeva Moilanen, Katriina Vuolteenaho

“…YKL-40 is associated with tissue injury and inflammation, and consequently to diseases in which these mechanisms lead to tissue degradation, for example, asthma and rheumatoid arthritis. …”
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Disparity of serum uric acid threshold for CKD among hypertensive and non-hypertensive individuals by Bowen Zhu, Fang Li, Weidong Zhang, Shuan Zhao, Nana Song, Shi Jin, Ziyan Shen, Yufei Lu, Yang Li, Hong Liu

“…For the hospital-based population, kidney injury was marked by a KIM-1 positive area.Results Our results indicate a higher prevalence of CKD in the community population with hypertension (10.2% vs. 3.9%, p < .001). …”
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Global, regional, and national epidemiology of allergic diseases in children from 1990 to 2021: findings from the Global Burden of Disease Study 2021 by Jun Zheng, Yi-jing Jin, Cheng-hai Wang, Chu Feng, Xin-yuan Lai, Shu-qing Hua, Jia-hui Tai

“…Methods The study utilized information from the Global Burden of Disease (GBD), Injuries, and Risk Factors Study 2021. The sample size for this study consisted of children with asthma or AD between the ages of 0 and 14. …”
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Respiratory Impairment after Early Red Cell Transfusion in Pediatric Patients with ALI/ARDS by Surender Rajasekaran, Dominic Sanfilippo, Allen Shoemaker, Scott Curtis, Sandra Zuiderveen, Akunne Ndika, Michael Stoiko, Nabil Hassan

“…In the first 48 hours of ventilating patients with acute lung injury (ALI)/acute respiratory distress syndrome (ARDS), a multipronged approach including packed red blood cell (PRBC) transfusion is undertaken to maintain oxygen delivery. …”
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Naringenin Protects against Acute Pancreatitis in Two Experimental Models in Mice by NLRP3 and Nrf2/HO-1 Pathways by Yong Li, Yiyuan Pan, Lin Gao, Jingzhu Zhang, Xiaochun Xie, Zhihui Tong, Baiqiang Li, Gang Li, Guotao Lu, Weiqin Li

“…In contrast, glutathione peroxidase (GPx), glutathione reductase (GR), glutathione S-transferase (GST), total sulfhydryl (T-SH), and non-proteinsulthydryl (NP-SH) were markedly increased in both MAP and SAP after Nar treatment. The injury in pancreatic and pulmonary tissues was markedly improved as evidenced by the inhibited expression of myeloperoxidase, nod-like receptor protein 3, and interleukin 1 beta as well as the enhanced expression of nuclear factor erythroid 2-related factor 2/heme oxygenase-1 in pancreatic tissues. …”
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