Roles of retinoic acid-related orphan receptor α in high glucose-induced cardiac fibroblasts proliferation by Wenqing San, Qianyou Zhou, Danning Shen, Danyi Cao, Yun Chen, Guoliang Meng

“…In conclusion, RORα antagonist SR3335 promoted cell injury and proliferation, enhanced collagen synthesis, facilitated oxidative stress and necroptosis in cardiac fibroblasts with high glucose stimulation, whereas RORα agonist SR1078 showed opposing effects. …”
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Optimizing implant positioning in total hip arthroplasty via the direct anterior approach: The role and technique of conventional traction table and fluoroscopy by Seiya Ishii, Tomonori Baba, Koju Hayashi, Yasuhiro Homma, Osamu Muto, Muneaki Ishijima

“…Complications were defined as dislocation, periprosthetic fracture, ankle fracture, implant loosening, nerve injury, surgical site infection, deep vein thrombosis, and revision surgery for any reason. …”
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Perioperative complications in primary intramedullary tumors of the spine in adults. A multicenter surveillance study of 307 patients from the German Spine Registry (DWG-Register) by Juan Manuel Vinas-Rios, Vincent J. Heck, Fatima Azucena Medina-Govea, Mario Alberto Islas-Aguilar, Nikolaus Kernich, DWG-Registry Group

“…The incidence of complications was: epidural hematoma n = 5 (8.4%), paresis n = 23 (38.9%), bowel/bladder dysfunction n = 15 (25.4%), wound infection n = 5 (8.4%), medullary injury n = 2 (3.4%), cerebrospinal fluid (CSF) leakage n = 15 (25.4%), and reintervention with hematoma, abscess, or surgical CSF leakage management in n = 22 (37.2%). …”
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Kinesiology Tape: A Descriptive Survey of Healthcare Professionals in the United States by Scott W Cheatham, Russell T Baker, Thomas E Abdenour

“…Most respondents used KT for post-injury treatment (74%), pain modulation (67%), and neuro-sensory feedback (60%). …”
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What do ultrasound vocalizations really mean in rats with different origins of pain? by Yang Yu, Chun-Li Li, Rui Du, Xiao-Liang Wang, Jun Chen

“…The major new gains were as follows: (1) naive rats staying alone and engaging dyadic social interaction with a naive or a conspecific in pain emitted similar power and amounts of both 22 kHz and 50 kHz spontaneous USV calls; however, rats suffering from various origins of pain emitted significantly less USV calls of both 22 kHz and 50 kHz in terms of both number and time. (2) Local blockade of the injury sites of inflammatory pain could reverse the impaired emission of both 22 kHz and 50 kHz spontaneous calls, so did the treatment of the rats with neuropathic pain by amitriptyline and gabapentin. …”
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Social determinants of the healthcare needs of undocumented migrants living with non-communicable diseases: a scoping review by Claudine Burton-Jeangros, Yves Jackson, Janeth Tenorio-Mucha, Corinne Jeffries-Tolksdorf, Jan-Erik Refle

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Peculiarities of Forming the Methodology for Investigating Criminal Offenses against the Authority of State Agencies in the Law Enforcement Sphere by V. O. Gusieva

“…It has been established that the specified group of criminal offenses includes: 1) interference in the activities of a law enforcement officer; 2) the threat of murder, bodily injury or destruction or damage to property in a generally dangerous manner in respect to an official or his relatives or in respect to a citizen performing public duties, used to terminate the activities of a citizen performing public duties or to change its nature in the interests of the person who makes threats; 3) unauthorized appropriation of powers combined with the commission of any socially dangerous actions. …”
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Conditional knockdown of hepatic PCSK9 ameliorates high-fat diet-induced liver inflammation in mice by Xue-Ying Zhang, Qing-Qing Lu, Yan-Jie Li, Shan-Rui Shi, Chao-Nan Ma, Miao Miao, Shou-Dong Guo

“…Moreover, the findings were verified in vitro using HepG2 cells.Results and DiscussionConditional knockdown of hepatic PCSK9 remarkably decreased plasma levels of total cholesterol and alleviated hyperlipidemia-induced liver injury. Mechanistically, conditional knockdown of hepatic PCSK9 significantly reduced the levels of pro-inflammatory factors by downregulating the expression of Toll-like receptors, mitogen-activated protein kinase (MAPK), and phosphoinositide-3 kinase/protein kinase B, which subsequently attenuated the expression of downstream molecules, namely nuclear factor kappa-B and activator protein-1. …”
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Construction of an lncRNA-mediated ceRNA network to investigate the inflammatory regulatory mechanisms of ischemic stroke. by Meimei Xu, Shan Yuan, Xing Luo, Mengsi Xu, Guangze Hu, Zhe He, Xinyuan Yang, Rui Gao

“…In this study, we established a cerebral ischemia-reperfusion injury model using middle cerebral artery occlusion (MCAO) in male Sprague-Dawley rats. …”
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Explaining the interactions of city and border with the sustainable development approach Based on the logic of fuzzy multi-criteria decision making Case study: Zahedan ,Mijaveh, D... by reza mohammadi, zyinab karkaabadi, ghlam reza miri

“…Findings and results showed.the most important effective factor on city-boundary relations is social factors with a mean of 3.55 and among weaknesses, Most affected were social weaknesses with a mean of 3.63 and among the opportunities examined, economic and managerial factors with a mean of 3.53 and Finally, they have the most impact on all types of threats, injuries and social threats with an average of 3.75. …”
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The Impact of Visual Perturbation Neuromuscular Training on Landing Mechanics and Neural Activity: A Pilot Study by Timothy R Wohl, Cody R Criss, Adam L Haggerty, Justin L Rush, Janet E Simon, Dustin R Grooms

“…# Background Athletes at risk for anterior cruciate ligament (ACL) injury have concurrent deficits in visuocognitive function and sensorimotor brain functional connectivity…”
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A Systematic Review on Serious Games in Attention Rehabilitation and Their Effects by Leila Shahmoradi, Fatemeh Mohammadian, Meysam Rahmani Katigari

“…Attention is a basic and main mental task and can play an important role in the functioning of other brain abilities such as intelligence, memory, learning, and perception, and its deficit occurs in 80% of patients with traumatic brain injury. The use of game-based tools for rehabilitation is rapidly expanding. …”
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Multiple Organ Failure Associated with SARS-CoV-2 Infection in a Child with Down Syndrome: Is Trisomy 21 Associated with an Unfavourable Clinical Course? by Perla Idalia Vazquez-Hernández, Alan Cárdenas-Conejo, Manuel Alejandro Catalán-Ruiz, Karla Navar-Gallegos, Emilio Zenteno-Salazar, Jose Rafael-Parra-Bravo, Ranferi Aragon-Nogales, Maribel Ibarra-Sarlat, Juan Carlos Núñez-Enríquez

“…Nonetheless, the patient developed respiratory and cardiac failure, acute renal injury (AKIN-III), and septic shock. After 24 days of hospitalization, the patient died. …”
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Traumatic Ulceration of the Vestibular Mucous Membrane After Insertion of Four Mini-Implants in the Atrophied Mandible: A Case Report by Domagoj Kilić, Sanja Peršić-Kiršić, Asja Čelebić

“…A few days after the implant insertion, injury, inflammation, and induration of the vestibular movable mucous membrane were observed on the movable vestibular mucosa on the right side, opposing the mini-implants. …”
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Impact of Endurance Exercise Training on Biomarkers of Aortic Endothelial Damage in Diabetic Rats by Mahtab Fouladi, Maryam Mahmoudabady, Zahra Gholamnezhad, Sadegh Shabab, Saeed Niazmand, Hossein Salmani

“…The aim is to elucidate the impact of different exercises (interval and continuous training) and metformin on biochemical parameters, aortic injury, oxidative stress, and inflammation to provide insights into potential therapeutic interventions for diabetes-associated vascular complications. …”
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Acute Effects of Dry Needling on Myofascial Trigger Points in the Triceps Surae of Ballet Dancers: A Pilot Randomized Controlled Trial by Jennifer A Janowski, Deanna M L Phelan-Smith, Maria N Kroat Brady, Kelsey L Michels, Alexandra H Timm, Nicole M Boucher, Kedron D Casteen, David Village, Mark D Sleeper

“…# Background There is convincing evidence that dancers suffer injuries to the triceps surae musculature. Research on the immediate effects of dry needling (DN) is limited, and it is important to understand the acute effects of this treatment prior to performance…”
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Analysis of the Renal Protection and Antioxidative Stress Effects of Panax notoginseng Saponins in Diabetic Nephropathy Mice by Wei Mi, Min Yu, Shuying Yin, Yuhan Ji, Tala Shi, Ning Li

“…SOD activity and GSH content in renal tissues of the model group mice decreased markedly versus the control group, and MDA, CRP, IL-6, and TGF-β1 contents elevated statistically, while different doses of PNS effectively reduced the OS injury and IFs in mice. Compared with the model group, PNS dose-dependently increased Nrf2 and HO-1 levels in DN mice. …”
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Alterations of triple network dynamic connectivity and repetitive behaviors after mini-basketball training program in children with autism spectrum disorder by Weike Zhang, Kelong Cai, Xuan Xiong, Lina Zhu, Zhiyuan Sun, Sixin Yang, Wei Cheng, Haiyong Mao, Aiguo Chen

“…Furthermore, a reduction in the RBS-R Total score was observed in the exercise group, reflecting improvements in self-injurious behavior and restricted behavior. Correlation analysis revealed that the amelioration of repetitive behaviors was associated with enhanced dynamic connectivity in parts of the triple network. …”
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Effect of Scapular Retraction on Lower Trapezius, Infraspinatus, and Deltoid Muscle Electromyographic Activity During the Side-Lying Abduction Exercise by Masaaki Tsuruike, Todd S. Ellenbecker

“…# Background The lower trapezius (LT) muscle, which stabilizes the scapula posteriorly during arm elevation, has been interesting to both clinicians and researchers for its importance in throwing-related shoulder rehabilitation and injury prevention. # Purpose The purpose of this study was to investigate the electromyographic activity of the LT and other relevant muscles during scapular and shoulder activities in the side-lying position…”
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CircTRRAP Knockdown Has Cardioprotective Function in Cardiomyocytes via the Signal Regulation of miR-370-3p/PAWR Axis by Yuan Zhang, Zhenggong Li, Jiao Wang, Hao Chen, Rui He, Hongkun Wu

“…Human cardiomyocyte AC16 was exposed to hypoxia to induce cell injury. Cell viability was detected through Cell Counting Kit-8. …”
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