Exploring the Molecular Modalities in the Pathogenesis of Diabetic Kidney Disease with a Focus on the Potential Therapeutic Implications by Lyubomir Gaydarski, Kristina Petrova, Ivan Angushev, Stancho Stanchev, Alexandar Iliev, Nikola Stamenov, Vidin Kirkov, Boycho Landzhov

“…Preclinical studies highlight its dual role in renal protection and injury through anti-inflammatory and antioxidant pathways, while other evidence suggests that it may exacerbate DKD through podocyte damage and angiogenesis. …”
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Ultrasound-based abdominal muscles and diaphragm assessment in predicting extubation failure in patients requiring neurointensive care: a single-center observational study by Xiang Qiu, Chuanjuan Chen, Lan Lv, Bihui Yang, Zhiqiang Wang, Jun Ni

“…Patients with primary central nervous system injury requiring invasive mechanical ventilation were included. …”
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Investigation of PACAP Fragments and Related Peptides in Chronic Retinal Hypoperfusion by Dora Werling, Dora Reglodi, Peter Kiss, Gabor Toth, Krisztina Szabadfi, Andrea Tamas, Zsolt Biro, Tamas Atlasz

“…Pituitary adenylate cyclase activating polypeptide (PACAP) has neuroprotective effects in different neuronal and retinal injuries. Retinal ischemia can be effectively modelled by permanent bilateral common carotid artery occlusion (BCCAO), which causes chronic hypoperfusion-induced degeneration in the entire rat retina. …”
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Upregulation of α3β1-Integrin in Podocytes in Early-Stage Diabetic Nephropathy by Kaichiro Sawada, Masao Toyoda, Noriko Kaneyama, Sawako Shiraiwa, Hitomi Moriya, Han Miyatake, Eitaro Tanaka, Naoyuki Yamamoto, Masaaki Miyauchi, Moritsugu Kimura, Takehiko Wada, Masafumi Fukagawa

“…Background. Podocyte injury plays an important role in the onset and progression of diabetic nephropathy (DN). …”
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Parthenolide improves sepsis-induced coagulopathy by inhibiting mitochondrial-mediated apoptosis in vascular endothelial cells through BRD4/BCL-xL pathway by Jun Zhang, Xing Zhu, Yong Li, Yinyu Wu, Yunxia Du, Hai Yang, Zhengchao Liu, Haoyu Pei, Rui Li, Huan Luo, Deyu Zuo, Han She, Qingxiang Mao

“…Results PTL has been shown to mitigate lung injury in septic rats, significantly reduce tumor necrosis factor-α (TNF-α) levels, and increase survival rates. …”
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The Effect of Antivascular Endothelial Growth Factor on the Development of Adhesion Formation in Laparotomized Rats: Experimental Study by Murat Basbug, Nurullah Bulbuller, Cemalettin Camci, Refik Ayten, Erhan Aygen, Ibrahim Hanifi Ozercan, Zulfu Arikanoglu, Sami Akbulut

“…All rats underwent laparotomy at which time cecal wall abrasion and abdominal wall injuries were induced. Group I (control) underwent only the abrasion procedure; Groups II and III received saline or bevacizumab intraperitoneally, respectively, following the abrasion. …”
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Importance of Cheese Whey Processing: Supplements for Sports Activities – a Review by Patricia Fassina, Gabriela Quadros Nunes, Fernanda Scherer Adami, Márcia Inês Goettert, Claucia Fernanda Volken de Souza

“…In this context, the objective of this review was to explore current evidence regarding the consumption of different WP supplements in sports nutrition to elucidate their efficiency in affecting muscle hypertrophy, physical performance, response to muscle injury, weight loss, and body composition changes. …”
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Frequency of Diplopia in Zygomatic Complex Fractures—A Cross-Sectional Descriptive Study by Maria Shabbir, Ruqaya Shah, Muhtada Ahmad, Rakhi Issrani, Zafar Khan, Salah Nazal Alotha, Basant Mousa Alsiyat, Mohammed Saad Alqarni, Ahmed Saleh Albalawi, Namdeo Prabhu, Mohammad Khursheed Alam, Zahid Qayyum

“…The prominent convex shape of the zygoma makes it vulnerable to traumatic injury. Diplopia is one of the serious complications of zygomatic complex fracture and is a common subjective complaint. …”
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Highly Proliferative Immortalized Human Dental Pulp Cells Retain the Odontogenic Phenotype when Combined with a Beta-Tricalcium Phosphate Scaffold and BMP2 by Xiangfen Li, Liu Wang, Qin Su, Ling Ye, Xuedong Zhou, Dongzhe Song, Dingming Huang

“…Conclusively, the established iHDPCs are a valuable resource for mechanistic study of dental pulp cell differentiation and dental pulp injury repair, as well as for applications in tooth regeneration.…”
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CXC chemokine receptor 7 ameliorates renal fibrosis by inhibiting β-catenin signaling and epithelial-to-mesenchymal transition in tubular epithelial cells by Ping Meng, Chunli Liu, Jingchun Li, Ping Fang, Bo Yang, Wei Sun, Yunfang Zhang

“…CXCR7 expression is decreased in unilateral ischemia–reperfusion injury (UIRI) and unilateral ureteral obstruction mouse models. …”
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An injectable, expandable polyacrylamide cryogel decreases blood loss and improves survival in a porcine model of junctional hemorrhage by Al-Murtadha Al-Gahmi, Syed Muntazir Andrabi, S. M. Shatil Shahriar, Carlos P. Jara, Jingwei Xie, Mark A. Carlson

“…EPC application for junctional-type injury produced wound tamponade with better survival, reduced blood loss, and better hemodynamic and laboratory parameters compared to no treatment, with trending improvements over XStat and CG.…”
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Poly-γ-Glutamic Acid Attenuates Angiogenesis and Inflammation in Experimental Colitis by Munkhtugs Davaatseren, Jin-Taek Hwang, Jae Ho Park, Myung-Sunny Kim, Shuaiyu Wang, Mi Jeong Sung

“…We found that γ-PGA significantly attenuated weight loss, DAI, and colon shortening. γ-PGA also significantly reduced histopathological evidence of injury. Moreover, γ-PGA significantly attenuated DSS-induced blood vessel densities. …”
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Correlation of ferritin and glutathione peroxidase 4 (GPX4) level as a marker of ferroptosis process in endometrioma by Rina Nulianti, Hartanto Bayuaji, Mulyanusa Amarullah Ritonga, Tono Djuwantono, Dian Tjahyadi, Anita Rachmawati, Sri Ratna Dwiningsih, Aisyah Shofiatun Nisa, Putri Nadhira Adinda Adriansyah

“…This disruption can trigger oxidative injury and an inflammatory response, leading to ferroptosis, particularly in the endometrioma phenotype. …”
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Investigating the Relationship between Traffic Violations and Crashes at Signalized Intersections: An Empirical Study in China by Ze-Hao Jiang, Xiao-Guang Yang, Tuo Sun, Tao Wang, Zheng Yang

“…Among the chosen 7 independent variables, four are significantly related to the dependent variable, namely, driving commercial vehicle during internship, wrong-way entry, speeding, and traffic-light violation. (3) With the increase of annual average daily traffic (AADT), the number of total crashes goes up; however, the injury-or-fatality rate decreases, which means that intersections with smaller traffic volumes tend to have higher traffic crash severity. …”
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PPARγ Agonist Rosiglitazone Suppresses Renal mPGES-1/PGE2 Pathway in db/db Mice by Ying Sun, Zhanjun Jia, Gang Liu, Li Zhou, Mi Liu, Baoxue Yang, Tianxin Yang

“…In line with the reduction of glomerular mPGES-1, the glomerular injury score showed a tendency of improvement after 1 week of Rosi therapy. …”
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Influence of Patient Gender on In‐Hospital Mortality: A Population‐Based Cross‐Sectional Study by Nahikari Vizuete‐Aldave, Maider Ugartemendia‐Yerobi, Beatriz Pereda‐Goikoetxea, Nagore Zinkunegi‐Zubizarreta, Josune Zubeldia‐Etxeberria, Udane Elordi‐Guenaga, Haritz Arrieta, Ainitze Labaka

“…In contrast, men were at greater risk of in‐hospital death from neoplasms (OR 0.86 [0.83–0.94], p < 0.05), diseases of the nervous system (OR 0.83 [0.70–0.97], p < 0.05), diseases of the genitourinary system (OR 0.83 [0.71–0.96], p < 0.05), endocrine diseases (OR 0.67 [0.54–0.84], p < 0.05), injury, poisoning and other consequences of external causes (OR 0.60 [0.54–0.67], p < 0.05) and diseases of the musculoskeletal system and connective tissue (OR 0.69 [0.50–0.93], p < 0.05). …”
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A qualitative analysis of unintended effects of a digital conditional cash transfer intervention to encourage healthcare utilization in Southern Madagascar by Mara Anna Franke, Anne Neumann, Kim Nordmann, Daniela Suleymanova, Onja Gabrielle Ravololohanitra, Samuel Knauss, Julius Valentin Emmrich

“…The intervention offered partial cost coverage for patients seeking care for potentially life-threatening conditions, accidents and injuries, maternal or pediatric care between February 2021 and June 2022. …”
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Changing Trends in Eye-Related Complaints Presenting to the Emergency Department in Beirut, Lebanon, over 15 Years by Haytham I. Salti, Carl-Joe Mehanna, Bachir Abiad, Nicola Ghazi, Samih Raad, Anita Barikian, Randa Haddad, Adnan Ashkar, Elie Harmouche, Elie Zaghrini, Afif Mufarrij

“…Diagnoses were classified into 4 categories according to the International Society of Ocular Trauma and include penetrating eye injuries, nonpenetrating eye trauma, nontraumatic ophthalmic emergencies, and nontraumatic, nonurgent ophthalmic conditions. …”
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Cangfudaotan Decoction Alleviates Insulin Resistance and Improves Follicular Development in Rats with Polycystic Ovary Syndrome via IGF-1-PI3K/Akt-Bax/Bcl-2 Pathway by Chenye Wang, Caifei Ding, Zhoujia Hua, Chunyue Chen, Jia Yu

“…CFD was able to improve IR, restore the serum hormone levels, inhibit the inflammatory cytokines in PCOS rat, and alleviate ovary morphological injury and apoptosis in PCOS rats. In granulosa cells of PCOS, the result showed that the cell viability was improved, and cell apoptosis was inhibited after CFD administration. …”
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Nitrooleic Acid Attenuates Lipid Metabolic Disorders and Liver Steatosis in DOCA-Salt Hypertensive Mice by Haiping Wang, Jing Sun, Zhanjun Jia, Tianxin Yang, Liang Xu, Bing Zhao, Kezhou Yu, Rong Wang

“…These findings indicated that OA-NO2 had the protective effect on liver injury against DOCA-salt administration and the beneficial effect could be attributed to its antihyperlipidemic activities.…”
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