Simultaneous total hip and knee arthroplasties in hemophilic arthropathy: series of 5 cases by Özgür Mert Bakan, Arman Vahabi, Elcil Kaya Biçer, Fahri Şahin, Kaan Kavaklı

“…Preoperative and postoperative evaluations included Harris Hip Score (HHS), Knee Society Score (KSS), Knee Injury and Osteoarthritis Outcome Score (KOOS), range of motion, flexion contracture (FC), Visual Analog Scale (VAS), hip-knee angle, and leg length discrepancy. …”
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Management of Diabetes Mellitus in Patients with Chronic Liver Diseases by Yingying Zhao, Huichun Xing, Xiaomei Wang, Weini Ou, Hong Zhao, Ben Li, Yue Li, Ying Duan, Liwei Zhuang, Wei Li, Danying Cheng, Min Quan, Yu Zhang, Shibo Ji

“…In addition to growing DM populations, DM complications are involving injuries to more organs, such as the heart and cerebral vessel damage. …”
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Technical Report on the New Ultrasound Lateral Mid-Shaft Approach to the Sciatic Nerve: A Never-Ending Story by Giuseppe Sepolvere, Mario Tedesco, Mario Cibelli, Dario Cirillo, Angelo Sparaco, Giuseppe Gagliardi, Giuseppina Costagliola, Loredana Cristiano, Valeria Rita Scialdone, Maria Rosaria Pasquariello, Fabrizio Di Zazzo, Luigi Merola, Mirco Della Valle, Daniela Arminio, Leonardo Maria Bottazzo, Marco Folliero, Giorgio Ranieri, Domenico Pietro Santonastaso, Antonio Coviello

“…Finally, it is performed in the supine position without the need to mobilize the lower limbs, ensuring patient comfort, especially in cases of fractures or lower limb injuries. Further studies are needed to confirm these results.…”
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Luteolin: exploring its therapeutic potential and molecular mechanisms in pulmonary diseases by Jialian Lv, Xinyue Song, Zixin Luo, Duoqin Huang, Li Xiao, Kang Zou

“…Luteolin has therapeutic effects on chronic obstructive pulmonary disease (COPD), acute lung injury/acute respiratory distress syndrome (ALI/ARDS), pulmonary fibrosis, allergic asthma, and lung cancer. …”
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Heart-Kidney Biomarkers in Patients Undergoing Cardiac Stress Testing by Mikko Haapio, Andrew A. House, Massimo de Cal, Dinna N. Cruz, Paolo Lentini, Davide Giavarina, Antonio Fortunato, Luigi Menghetti, Matteo Salgarello, Andrea Lupi, Giuliano Soffiati, Alessandro Fontanelli, Pierluigi Zanco, Claudio Ronco

“…We examined association of inducible myocardial perfusion defects with cardiorenal biomarkers, and of diminished left ventricular ejection fraction (LVEF) with kidney injury marker plasma neutrophil gelatinase-associated lipocalin (NGAL). …”
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Intra-rater reliability and validity of navicular drop test for the assessment of medial longitudinal arch in patients having pronated feet with chronic low back pain by Md Farhan Alam, Saima Zaki, Saurabh Sharma, Mohammed Ghareeb, Shibili Nuhmani

“…Pronated feet (PF) are considered to be associated with lower limb injuries and low back pain (LBP). Hence, a highly reliable assessment method for accurately diagnosing foot protonation is essential. …”
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Chimonanthus nitens Oliv. leaves flavonoids alleviate hyperuricemia by regulating uric acid metabolism and intestinal homeostasis in mice by Wenya Meng, Lingli Chen, Kehui Ouyang, Suyun Lin, Yang Zhang, Jing He, Wenjun Wang

“…In addition, CLF repaired renal injury by significantly down-regulating mRNA and protein expressions of renal UA reabsorption-related proteins and up-regulating the mRNA and protein expressions of UA secretory-related proteins. …”
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Radiation Induces Pulmonary Fibrosis by Promoting the Fibrogenic Differentiation of Alveolar Stem Cells by Lu-Kai Wang, Tsai-Jung Wu, Ji-Hong Hong, Fang-Hsin Chen, John Yu, Chun-Chieh Wang

“…However, the role of lung stem cells (LSCs) in the development of radiation-induced lung injury is still unclear. In this study, we found that both LSCs and LSC-derived type II alveolar epithelial cells (AECII) can repair radiation-induced DNA double-strand breaks, but the irradiated LSCs underwent growth arrest and cell differentiation faster than the irradiated AECII cells. …”
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Influence of <i>Apis mellifera syriaca</i> Bee Venom on Nociception and Inflammatory Cytokine Profiles in Experimental Hyperalgesia by Mohamad Ayoub, Salma Fayjaloun, Rabih Roufayel, Dany El Obeid, Ziad Fajloun, Mohamad Rima, Marc Karam

“…Hyperalgesia is a condition marked by an abnormal increase in pain sensitivity, often occurring in response to tissue injury, inflammation, or prolonged exposure to certain medications. …”
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Protein Kinase A Is Involved in Neuropathic Pain by Activating the p38MAPK Pathway to Mediate Spinal Cord Cell Apoptosis by Yajun Deng, Liang Yang, Qiqi Xie, Fengbiao Yang, Guoqiang Li, Guangzhi Zhang, Shaoping Li, Zuolong Wu, Jing Wang, Xuewen Kang

“…A neuropathic pain-related gene expression dataset was downloaded from Gene Expression Omnibus, and differentially expressed genes were screened using the R software. cytoHubba was used to screen for hub genes. A spared nerve injury (SNI) rat model was established, and the paw withdrawal threshold was determined using von Frey filaments. …”
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Anti-Inflammatory Functions of Protein C Require RAGE and ICAM-1 in a Stimulus-Dependent Manner by Natascha Braach, Kirsten Buschmann, Johanna Pflaum, Hannes Hudalla, Lutz Koch, Eduard Ryschich, Johannes Poeschl, David Frommhold

“…In contrast to WT and Icam-1−/− mice, PC had no effect on bronchoalveolar neutrophil emigration in RAGE−/− mice during LPS-induced acute lung injury, suggesting that RAGE critically mediates PC effects during acute lung inflammation. …”
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Time-lapse imaging of identified granule cells in the mouse dentate gyrus after entorhinal lesion in vitro reveals heterogeneous cellular responses to denervation by Davide Greco, Alexander Drakew, Nina Rößler, Nina Rößler, Tassilo Jungenitz, Peter Jedlicka, Peter Jedlicka, Thomas Deller

“…Denervation of neurons is a network consequence of brain injury. The effects of denervation on neurons can be readily studied in vitro using organotypic slice cultures of entorhinal cortex and hippocampus. …”
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Expression of Glutathione Peroxidase and Glutathione Reductase and Level of Free Radical Processes under Toxic Hepatitis in Rats by Igor Y. Iskusnykh, Tatyana N. Popova, Aleksander A. Agarkov, Miguel Â. A. Pinheiro de Carvalho, Stanislav G. Rjevskiy

“…Correlation between intensity of free radical processes estimated by biochemiluminesce parameters, content of lipoperoxidation products, and changes of glutathione peroxidase (GP, EC 1.11.1.9) and glutathione reductase (GR, EC 1.6.4.2) activities at rats liver injury, after 12, 36, 70, 96, 110, and 125 hours & tetrachloromethane administration have been investigated. …”
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The impact of uric acid on musculoskeletal diseases: clinical associations and underlying mechanisms by Jing Zhang, Na Sun, Wanhao Zhang, Wenjie Yue, Xiaochen Qu, Xiaochen Qu, Zhonghai Li, Zhonghai Li, Gang Xu, Gang Xu

“…This review discusses the mechanisms linking SU to musculoskeletal disorders, as well as the clinical associations of SU with conditions such as sarcopenia, T2D with sarcopenia, McArdle disease, heart failure, gout, OA, IDD, OP and exercise-induced acute kidney injury (EIAKI), offering valuable insights for improved prevention and treatment strategies. …”
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Spontaneous Physical Activity Downregulates Pax7 in Cancer Cachexia by Dario Coletti, Paola Aulino, Eva Pigna, Fabio Barteri, Viviana Moresi, Daniela Annibali, Sergio Adamo, Emanuele Berardi

“…We evaluated the muscle regenerative potential after acute injury in C26 colon carcinoma tumor-bearing mice and healthy controls. …”
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Evaluating the Relationship of GDF-15 with Clinical Characteristics, Cardinal Features, and Survival in Multiple Myeloma by Małgorzata Banaszkiewicz, Jolanta Małyszko, Krzysztof Batko, Ewa Koc-Żórawska, Marcin Żórawski, Paulina Dumnicka, Artur Jurczyszyn, Karolina Woziwodzka, Joanna Tisończyk, Marcin Krzanowski, Jacek Małyszko, Anna Waszczuk-Gajda, Ryszard Drożdż, Marek Kuźniewski, Katarzyna Krzanowska

“…Increased GDF-15 concentrations were associated with more advanced MM stage, anemia, renal impairment (lower glomerular filtration and higher markers of tubular injury), and inflammation. Most of the results were confirmed in the subgroup analysis. …”
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Examining the effect of salbutamol use in ozone air pollution by people with exercise‐induced bronchoconstriction by Bennett T. Stothers, Andy Hung, Patric E. O. Gonçalves, Lulu X. Pei, Tessa van deKerkhof, Jem I. Arnold, Owen D. Harris, Nadine Borduas‐Dedekind, Andrew W. Sheel, Michael S. Koehle

“…Abstract Previous studies based on animal models have raised concerns about salbutamol use in ozone air pollution with regard to ozone related lung injury. We conducted a double‐blind, randomized, placebo‐controlled crossover study including 18 subjects diagnosed with EIB by a eucapnic voluntary hyperpnea (EVH) test. …”
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Increased Expression of VEGF and CD31 in Postradiation Rectal Tissue: Implications for Radiation Proctitis by G. Karamanolis, I. Delladetsima, V. Kouloulias, K. Papaxoinis, I. Panayiotides, D. Haldeopoulos, K. Triantafyllou, N. Kelekis, S. D. Ladas

“…Our results showed that in postradiation rectal biopsy specimens neoangiogenesis seems to be inflammation-related and constitutes a significant postradiation component of the tissue injury.…”
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Prophylactic Subacute Administration of Zinc Increases CCL2, CCR2, FGF2, and IGF-1 Expression and Prevents the Long-Term Memory Loss in a Rat Model of Cerebral Hypoxia-Ischemia by Victor Manuel Blanco-Alvarez, Guadalupe Soto-Rodriguez, Juan Antonio Gonzalez-Barrios, Daniel Martinez-Fong, Eduardo Brambila, Maricela Torres-Soto, Ana Karina Aguilar-Peralta, Alejandro Gonzalez-Vazquez, Constantino Tomás-Sanchez, I. Daniel Limón, Jose R. Eguibar, Araceli Ugarte, Jeanett Hernandez-Castillo, Bertha Alicia Leon-Chavez

“…We explored whether zinc prevents the cerebral cortex-hippocampus injury through regulation of CCL2, CCR2, FGF2, and IGF-1 expression following a 10 min of common carotid artery occlusion (CCAO). …”
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Protective Effect of Liposome-Encapsulated Glutathione in a Human Epidermal Model Exposed to a Mustard Gas Analog by Victor Paromov, Sudha Kumari, Marianne Brannon, Naga S. Kanaparthy, Hongsong Yang, Milton G. Smith, William L. Stone

“…HD/CEES are rapidly absorbed in the skin causing extensive injury. We hypothesize that antioxidant liposomes that deliver both water-soluble and lipid-soluble antioxidants protect skin cells from immediate CEES-induced damage via attenuating oxidative stress. …”
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