Hyperuricemia: An Early Marker for Severity of Illness in Sepsis by Sana R. Akbar, Dustin M. Long, Kashif Hussain, Ahmad Alhajhusain, Umair S. Ahmed, Hafiz I. Iqbal, Ailia W. Ali, Rachel Leonard, Cheryl Dalton

“…Secondary end points were Acute Kidney Injury (AKI), mortality, Acute Respiratory Distress Syndrome (ARDS), and duration of stay. …”
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Cervical Bone Graft Candida albicans Osteomyelitis: Management Strategies for an Uncommon Infection by Carlo Brembilla, Luigi Andrea Lanterna, Andrea Risso, Giuseppe Bonaldi, Paolo Gritti, Bruno Resmini, Andrea Viscone

“…The current case concerns a 27-year-old man with a spinal cord injury who, after undergoing anterior cervical fixation and fusion surgery, developed postoperative systemic bacterial infection and required long-term antibiotic therapy. …”
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Timing of surgery in acute burn care: A multicentre registry-based cohort study by Roos F.C. Salemans, Denise van Uden, Ymke Lucas, Anouk Pijpe, Eelke Bosma, Esther Middelkoop, Michiel H.J. Verhofstad, Margriet E. van Baar, Cornelis H. van der Vlies

“…This study analysed the timing of surgery in Dutch burn care by examining patient, injury and treatment characteristics, and clinical outcomes. …”
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Clinical Outcome and Fusion Rates after the First 30 Extreme Lateral Interbody Fusions by Gregory M. Malham, Ngaire J. Ellis, Rhiannon M. Parker, Kevin A. Seex

“…Complications were observed: clinical subsidence, cage breakage upon insertion, new postoperative motor deficit and bowel injury. Approach side-effects were radiographic subsidence and anterior thigh sensory changes. …”
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Falls Reduction and Exercise Training in an Assisted Living Population by Kimberly J. Alvarez, Shannen Kirchner, Serena Chu, Sarah Smith, Wendy Winnick-Baskin, Thelma J. Mielenz

“…This study aimed to examine the association between the Boston FICSIT (Frailty and Injuries: Cooperative Studies of Intervention Techniques) exercise program (the original exercise program to demonstrate that nursing home residents can increase strength) and falls incidents in an assisted living community. …”
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Implementation of the seven steps of patient safety in primary healthcare by Nur Syarianingsih Syam, Linda Tri Maryuni, Siti Kurnia Widi Hastututi, Sely Aprianda Syah Putri

“…One of the quality management indicators is patient safety, the safety steps are building awareness of the value of patient safety, leading and supporting staff, integrating risk reporting activities, developing reporting systems, involving and communicating with patients, learning and sharing experiences about patient safety, and preventing injuries through the implementation of patient safety systems. …”
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The Causative Pathogen Determines the Inflammatory Profile in Cerebrospinal Fluid and Outcome in Patients with Bacterial Meningitis by Denis Grandgirard, Rahel Gäumann, Boubacar Coulibaly, Jean-Pierre Dangy, Ali Sie, Thomas Junghanss, Hans Schudel, Gerd Pluschke, Stephen L. Leib

“…The brain’s inflammatory response to the infecting pathogen determines the outcome of bacterial meningitis (BM), for example, the associated mortality and the extent of brain injury. The inflammatory cascade is initiated by the presence of bacteria in the cerebrospinal fluid (CSF) activating resident immune cells and leading to the influx of blood derived leukocytes. …”
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Global trends of delayed graft function in kidney transplantation from 2013 to 2023: a bibliometric analysis by Zhiling Yao, Mingqian Kuang, Zhen Li

“…These emerging trends include ‘brain death donors’, ‘blood absence re-injection injuries’, ‘tacrolimus’, ‘older donors and recipients’, and ‘artificial intelligence and DGF’. …”
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Liver diseases: epidemiology, causes, trends and predictions by Can Gan, Yuan Yuan, Haiyuan Shen, Jinhang Gao, Xiangxin Kong, Zhaodi Che, Yangkun Guo, Hua Wang, Erdan Dong, Jia Xiao

“…Various factors including viruses, alcohol, metabolites, toxins, and other pathogenic agents can compromise liver function, leading to acute or chronic injury that may progress to end-stage liver diseases. …”
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Assessment of Postresuscitation Volume Status by Bioimpedance Analysis in Patients with Sepsis in the Intensive Care Unit: A Pilot Observational Study by Bram Rochwerg, Jason H. Cheung, Christine M. Ribic, Faraz Lalji, France J. Clarke, Susheel Gantareddy, Nischal Ranganath, Aziz Walele, Ellen McDonald, Maureen O. Meade, Deborah J. Cook, Trevor T. Wilkieson, Catherine M. Clase, Peter J. Margetts, Azim S. Gangji

“…Secondary clinical outcomes included ventilator status and acute kidney injury. Proof of concept was sought by correlating baseline VL measurements with other known measures of volume status. …”
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Assessment of Anterior Loop of Inferior Alveolar Nerve and Its Anatomic Variations with Age, Gender, and Dentition Status in Indian Population: A CBCT Study by Anjali Gupta, Sandeep Kumar, Siddharth Kumar Singh, Arunoday Kumar, Abhishek Gupta, Palkin Mehta

“…The use of the CBCT technique and appropriate preplanning prior to surgery or implant placement should be performed to prevent nerve injury.…”
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Evaluation of the Effects of Different Bacteroides vulgatus Strains against DSS-Induced Colitis by Sijia Li, Chen Wang, Chengcheng Zhang, Yanhong Luo, Qianqian Cheng, Leilei Yu, Zhen Sun

“…Compared to the other three tested strains, B. vulgatus 7K1 more strongly ameliorated the DSS-induced weight loss, shortening of the colon length, increased disease activity index scores, colonic tissue injury, and immunomodulatory disorder. In contrast, B. vulgatus 51K1 significantly worsened the DSS-induced alterations in the tumor necrosis factor-alpha (TNF-α) concentration and colonic histopathology. …”
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Recurrent Massive Hydrothorax in a Patient with Decompensated Liver Cirrhosis by K. S. Zemlyanukhina, I. N. Tikhonov, M. S. Zharkova, O. Yu. Kiseleva, R. Т. Rzayev, V. T. Ivashkin

“…Laboratory tests revealed signs of systemic inflammation, liver failure, and acute kidney injury. According to the results of instrumental studies, massive hydrothorax was noted in the right pleural cavity. …”
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Therapeutic Effect of Ginsenoside Rd on Experimental Autoimmune Encephalomyelitis Model Mice: Regulation of Inflammation and Treg/Th17 Cell Balance by Bo Jin, Chixiao Zhang, Yu Geng, Mei Liu

“…In this study, we investigated the therapeutic effect of Ginsenoside Rd on EAE in vivo and in vitro and also explored the potential mechanisms for alleviating the injury of EAE. The results indicated that Ginsenoside Rd was effective for the treatment of EAE in mice and splenocytes. …”
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Solo Sonographically Guided PCNL under Spinal Anesthesia: Defining Predictors of Success by Akbar Nouralizadeh, Hamid Pakmanesh, Abbas Basiri, Mohammad Aayanifard, Mohammad Hossein Soltani, Ali Tabibi, Farzaneh Sharifiaghdas, Seyed Amir Mohsen Ziaee, Naser Shakhssalim, Reza Valipour, Behzad Narouie, Mohammad Hadi Radfar

“…There was no cases of organ injury or death. Conclusion. Solo ultrasonographically guided PCNL under spinal anesthesia is feasible with an acceptable stone-free rate and complication rate.…”
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Integrated analysis of genetic, proteinic, and metabolomic alterations in Behcet’s disease by Yanlin Pu, Jing Liang, Yao Wang, Wanyun Zhang, Chuiren Zhou, Ju Shao, Jin Hu, Minghui Chen, Yunjie Shi, Yongdan Mao, Zhijun Chen

“…Collectively, this study showed that the hyperactivity of Th1 and Th17 responses played an essential role in the pathogenesis of BD, and the progression of this disease was associated with enhanced neutrophil chemotaxis, vascular endothelial injury, activation of haemostatic system, and oxidative stress.…”
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Subtoxic Concentrations of Hepatotoxic Drugs Lead to Kupffer Cell Activation in a Human In Vitro Liver Model: An Approach to Study DILI by Victoria Kegel, Elisa Pfeiffer, Britta Burkhardt, Jia L. Liu, Katrin Zeilinger, Andreas K. Nüssler, Daniel Seehofer, Georg Damm

“…Drug induced liver injury (DILI) is an idiosyncratic adverse drug reaction leading to severe liver damage. …”
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Reactive Metabolites and AGE-RAGE-Mediated Inflammation in Patients following Liver Transplantation by Thorsten Brenner, Thomas H. Fleming, David Spranz, Peter Schemmer, Thomas Bruckner, Florian Uhle, Eike O. Martin, Markus A. Weigand, Stefan Hofer

“…Recent investigations have indicated that reactive metabolites and AGE-RAGE-mediated inflammation might play an important role in the pathogenesis of ischemia-reperfusion injury in liver transplantation. In this observational clinical study, 150 patients were enrolled following liver transplantation from deceased donors. …”
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Biological activity produced by ruthenium chloride on perfusion pressure, left ventricular pressure and heart failure using an isolated rat heart model by Figueroa-Valverde Lauro, Rosas-Nexticapa Marcela, Alvarez-Ramirez Magdalena, Lopez-Ramos Maria, Aguilar-Sanchez Emilio, Mateu-Armand Virginia

“…Finally, biological activity of ruthenium chloride (1 to 100 nM) against heart failure was evaluated using an ischemia/reperfusion injury model. Results: The results showed that ruthenium chloride increased the perfusion pressure from 1 to 100 nM; ruthenium chloride increased LVP in a dose-dependent manner, whose effect was inhibited by prazosin and WB-4101; and the ruthenium derivative significantly decreased the infarct area (p = 0.05) compared with the control conditions. …”
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Dual functional hydrogel of osteoclastic-inhibition and osteogenic-stimulation for osteoporotic bone defect regeneration by Lei Yu, Wentao Wang, Chang Lv, Qian Chen, Peng Yang, Zhenrong Qi, Haomiao Yu, Ruiqi Cao, Wenhao Li, Yi Qin, Gaoran Ge, Peilai Liu, Lixin Zhu, Houyi Sun, Dechun Geng, Liang Zhang

“…This complicates the treatment of osteoporosis and its related bone injuries in clinical practice. Despite the development of various polymer scaffolds for bone defect repair, achieving effective regeneration in osteoporotic bones—especially when combined with osteoporosis medications—remains difficult. …”
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