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4661
Innate Immune Signaling in the Pathogenesis of Necrotizing Enterocolitis
Published 2013-01-01“…In seeking to understand the molecular and cellular processes that lead to NEC development, we have identified a critical role for the receptor for bacterial lipopolysaccharide (LPS) toll like receptor 4 (TLR4) in the pathogenesis of NEC, as its activation within the intestinal epithelium of the premature infant leads to mucosal injury and reduced epithelial repair. The expression and function of TLR4 were found to be particularly elevated within the intestinal mucosa of the premature as compared with the full-term infant, predisposing to NEC development. …”
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4662
Validation of preoperative predictor score for difficult laparascopic cholecystectomy and a modified intraoperative grading score of the difficulty of laparascopic cholecystectomy:...
Published 2025-01-01“…Abstract Background Difficult laparascopic cholecystectomy has greater risk of biliary, vascular and visceral injuries. A tool to predict the difficulty help to prepare a head and avoid complications. …”
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4663
Comparison of Clinical Safety and Outcomes of Early versus Delayed Laparoscopic Cholecystectomy for Acute Cholecystitis: A Meta-Analysis
Published 2014-01-01“…There was no significant difference between the two groups in terms of bile duct injury (Peto odds ratio 0.49 (95% confidence interval 0.05 to 4.72); P=0.54) or conversion to open cholecystectomy (risk ratio 0.91 (95% confidence interval 0.69 to 1.20); P=0.50). …”
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4664
Characterization of patients with thoracic trauma treated at the Enrique Cabrera Hospital. 2014-2018
Published 2019-12-01“…The variables analyzed were: age, sex, cause and type of trauma, type of injury, treatment, complications and hospital stay. …”
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4665
Organization of Emergency Health Services and Problems in Flood Disasters: The Case of Hopa
Published 2022-07-01“…The Hopa flood disaster that occurred on August 24, 2015, caused many injuries, 3 people were lost in the flood waters and 8 people lost their lives in addition to financial losses. …”
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4666
Airway basal stem cell therapy for lung diseases: an emerging regenerative medicine strategy
Published 2025-01-01“…Airway BSCs, which are strongly capable of self-renewal and multi-lineage differentiation, can effectively attenuate airway epithelial injury caused by environmental factors or genetic disorders, such as cystic fibrosis. …”
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4667
“Pure Fat Flap”—Perforator-based Adiposal Layer Only Flap for Lateral Ankle Reconstruction
Published 2025-01-01“…Traditional reconstruction methods using fasciocutaneous flaps may result in donor site morbidity such as delayed wound healing or nerve injury. In this article, we present a case of diabetes-related lateral ankle defect successfully treated using adiposal layer only flap, also known as pure fat flap. …”
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4668
Ethylene Glycol Poisoning: An Unusual Cause of Altered Mental Status and the Lessons Learned from Management of the Disease in the Acute Setting
Published 2016-01-01“…We present the case of an elderly male with altered mental status, acute kidney injury, elevated anion gap metabolic acidosis, and profound lactate and osmolal gaps.…”
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4669
Effects of Carbon Dioxide Therapy on Skin Wound Healing
Published 2025-01-01“…The most researched type of injury was chronic wounds located on the extremities of the limbs. …”
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4670
In Situ Cytokine Expression and Morphometric Evaluation of Total Collagen and Collagens Type I and Type III in Keloid Scars
Published 2017-01-01“…Keloids are characterized by excessive collagen deposition and growth beyond the edges of the initial injury, and cytokines may be related to their formation. …”
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4671
Giant Cell Tumor of Lower End of Tibia
Published 2013-01-01“…A 35-year-old patient presented with complains of pain and swelling in left ankle since 1 year following a twisting injury to his left ankle. On examination, swelling was present over the distal and anterior part of leg and movements of ankle joint were normal. …”
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4672
Structural and Functional Fundamentals of Alcoholic Disease
Published 2018-11-01“…AD is defined as a condition, in which chronic ethanol intoxication leads to the development of morphological changes in organs and systems: from minimal injuries of the microcirculatory pathway to a multiple organ pathology showing signs of alcoholism. …”
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4673
Resolution of Crizotinib-Associated Fulminant Hepatitis following Cessation of Treatment
Published 2018-01-01“…Still, unintended, often idiosyncratic side effects, such as drug-induced liver injury, can occur. We discuss the case of a 26-year-old female with a history of ROS1-rearranged lung adenocarcinoma, undergoing treatment with the tyrosine kinase inhibitor crizotinib, who presented to our hospital with abdominal pain and scleral icterus. …”
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4674
Hominin heritage: How institutional repositories are managing collections, collaboration and repatriation
Published 2025-02-01“…We outline some of the complexities that museums, universities, and heritage bodies face in navigating human evolution research, site and material access, potential returns, repatriations or reburials, curation and the development of accessible educational content in a contemporary context. …”
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4675
Cervical Spine Mechanism for Reproduction of the Biomechanical Behaviours of the Human Neck during Rotation-Traction Manipulation
Published 2017-01-01“…However, a high rate of cervical injury occurs due to inexperienced physician interns who lack sufficient training. …”
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4676
BMSCs Interactions with Adventitial Fibroblasts Display Smooth Muscle Cell Lineage Potential in Differentiation and Migration That Contributes to Neointimal Formation
Published 2016-01-01“…In this study a model of simulated vascular injury in vitro was used to study the characterization of bone-marrow-derived mesenchymal stem cells (BMSCs) morphology and to investigate the differentiation and migration of BMSCs in the presence of adventitial fibroblasts. …”
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4677
Nasogastric Tube Feeding-Induced Esophageal Bezoar: Case Description
Published 2017-01-01“…Patient sustained anoxic brain injury after resuscitation, rendering him ventilator dependant along with nasogastric tube feeding, initially. …”
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4678
The effect of hamstring /quadriceps muscle strength ratio on plantar pressure distribution - A pilot study
Published 2024-12-01“…These insights may underscore the importance of balanced muscle function for maintaining proper gait mechanics and preventing lower extremity injuries. The study highlights the necessity of integrating muscle strength assessments in clinical evaluations to enhance musculoskeletal health and functional mobility.…”
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4679
Mesenchymal Stem Cells in Renal Fibrosis: The Flame of Cytotherapy
Published 2019-01-01“…Renal fibrosis, as the fundamental pathological process of chronic kidney disease (CKD), is a pathologic extension of the normal wound healing process characterized by endothelium injury, myofibroblast activation, macrophage migration, inflammatory signaling stimulation, matrix deposition, and remodelling. …”
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4680
Mitochondrial- and Endoplasmic Reticulum-Associated Oxidative Stress in Alzheimer's Disease: From Pathogenesis to Biomarkers
Published 2012-01-01“…In this paper we discuss the critical role of mitochondrial and ER dysfunction in oxidative injury in AD cellular and animal models, as well as in biological fluids from AD patients. …”
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