Update on long-term outcomes of a cohort of patients with TCF3::HLF positive acute lymphoblastic leukemia treated with blinatumomab and stem cell transplantation by Aida Zeckanovic, Brice Mouttet, Luciana Vinti, Philip Ancliff, Benoît Brethon, Gunnar Cario, Sarah Elitzur, Volkan Hazar, Joachim Kunz, Anja Möricke, Jerry Stein, Yöntem Yaman, Jochen Buechner, Magnus Aasved Hjort, David O’Connor, Angus Hodder, Jack Bartram, Julia Alten, Draga Barbaric, Gabriele Escherich, Nicolas Boissel, Loïc Vasseur, Emmanuelle Clappier, Laure Farnault, Sarah Bonnet, Katharine Patrick, Martin Schrappe, Sema Anak, André Baruchel, Franco Locatelli, Martin Stanulla, Arend von Stackelberg, Nicole Bodmer, Jean-Pierre Bourquin

Get full text

Shining light on knee osteoarthritis: an overview of vitamin D supplementation studies by Di Zhang, Miaoyu Ye, Yao Xu, Luyu Jiang, Yanmei Hu, Qi Zhang, Xiao Han, Qian Dai, Junhui Qian, Jian Luo, Qiang Yuan

“…Then, provides clinical evidence and recommendations the clinical use of vitamin D supplementation.MethodsTwo individuals reviewed and collected data from four databases until October 2023. AMSTAR-2, ROBIS, PRISMA 2020, and GRADE tools were used to evaluate the methodological quality, bias risk, reporting quality, and evidence strength of all SR/MA. …”
Get full text

Previous Exercise Training Reduces Markers of Renal Oxidative Stress and Inflammation in Streptozotocin-Induced Diabetic Female Rats by Liliany Souza de Brito Amaral, Cláudia Silva Souza, Rildo Aparecido Volpini, Maria Heloisa Massola Shimizu, Ana Carolina de Bragança, Daniele Canale, Antonio Carlos Seguro, Terezila Machado Coimbra, Amélia Cristina Mendes de Magalhães, Telma de Jesus Soares

“…The aim of this study is to evaluate the effects of regular moderate exercise training initiated previously or after induction of diabetes mellitus on renal oxidative stress and inflammation in STZ-induced diabetic female rats. For this purpose, Wistar rats were divided into five groups: sedentary control (SC), trained control (TC), sedentary diabetic (SD), trained diabetic (TD), and previously trained diabetic (PTD). …”
Get full text

Effects of Electroacupuncture at Fengchi Acupoint on Myosatellite Cells and TLR4/MyD88/NF-κB Signaling Pathway in Chronic Cervical Muscle Injury Rats by HUANG Yuting, CHEN Jiayan, KAN Yu, FANG Yanping, WANG Jinwei, ZHENG Linyao, JING Xianghong, LIAO Jun

“…ObjectiveTo observe effects of electroacupuncture at Fengchi acupoint on expression of myosatellite cells, myogenic determining factor (MyoD), proliferating cell nuclear antigen (PCNA), Toll-like receptor 4 (TLR4), myeloid differentiation primary response gene 88 (MyD88) and nuclear factor-kappa B p65 (NF-κBp65) protein in rat with chronic cervical muscle injury, so as to explore possible mechanism of electroacupuncture in promoting the repair of chronic cervical muscle injury.MethodsTen Wistar rats were selected from 45 Wistar rats as blank group, and the remaining rats were divided into model group, electroacupuncture group (EA group) and meloxicam group according to random number table method, with 10 rats in each group (5 rats were unsuccessful in modeling). …”
Get full text

Real-world survival outcomes with immune checkpoint inhibitors in large-cell neuroendocrine tumors of lung by Samuel Kareff, Jair Bar, Amir Onn, Alona Zer, Chul Kim, Stephen V Liu, Elizabeth Dudnik, Mor Moskovitz, Anastasiya Lobachov, Teodor Gottfried, Damien Urban, Ofer Rotem, Mira Wollner

Get full text

Pengaruh Papain Getah Pepaya Terhadap Pembentukan Jaringan Granulasi pada Penyembuhan Luka Bakar Tikus Percobaan by Meishinta Fitria, Deddy Saputra, Gusti Revilla

“…Subjek penelitian adalah 10 ekor tikus Wistar jantan yang dibagi menjadi dua kelompok, yaitu kelompok kontrol (K) dan kelompok perlakuan (P). …”
Get full text

Comparing the efficacy of 3D-printing-assisted surgery with traditional surgical treatment of fracture: an umbrella review by Lin Xiao, Peiyuan Tang, Shengwu Yang, Jingyue Su, Wenbo Ma, Han Tan, Ying Zhu, Wenfeng Xiao, Ting Wen, Yusheng Li, Shuguang Liu, Zhenhan Deng

“…Results Results from 14 meta-analyses were combined. AMSTAR 2 gave six meta-analyses a high rating, six MAs a moderate rating, and two MAs a low rating. …”
Get full text

Synergistic Effects of Cinnamomum verum and Stingless Bee Honey on Isoproterenol-induced Cardiac Hypertrophic Murine Model by Arul Mozhi Padmanabhan, Victor Arokia Doss

“…Materials and Methods: Isoproterenol (ISO-group II-30 mg/kg)-induced cardiac hypertrophic Wistar rats were used in this study. Hypertrophic rats were treated using the reference drug losartan (LOS Group III: 50 mg/kg) and aqueous extracts of C. verum barks and SBH (ACH Group IV: 250 mg/kg and 250 mg/kg). …”
Get full text

BEHAVIOR OF RAT NEONATES WITH INHERITED STRESS-INDUCED ARTERIAL HYPERTENSION by I. O. Meshkov, T. A. Alekhina, T. A. Moreva

“…The strains were: rats with inherited stress-induced arterial hypertension (ISIAH) and Wistar Albino Glaxo (WAG) rats as control. Different dynamics of weight gain and vibrissae growth were shown. …”
Get full text

Comparative Evaluation of Enalapril and Losartan in Pharmacological Correction of Experimental Osteoporosis and Fractures of Its Background by D. S. R. Rajkumar, A. V. Faitelson, O. S. Gudyrev, G. M. Dubrovin, M. V. Pokrovski, A. V. Ivanov

“…In the experiment on the white Wistar female rats (222 animals), the osteoprotective effect of enalapril and losartan was studied on experimental models of osteoporosis and osteoporotic fractures. …”
Get full text

Classification of Buried Objects From Ground Penetrating Radar Images by Using Second-Order Deep Learning Models by Douba Jafuno, Ammar Mian, Guillaume Ginolhac, Nickolas Stelzenmuller

Get full text

Educação Financeira: Tomar Decisão a Partir da Comparação de Dados de Amortização by Paulo Victor Delgado Pereira, Chang Kuo Rodrigues, Denise Mansoldo Salazar

“…Conhecer os procedimentos e as técnicas de amortização definirá, sobretudo, a postura que o indivíduo irá adotar, ao tomar decisões relativas à sua atuação consciente no mundo que o cerca. …”
Get full text

Slow Late Component in Conditioned Stimulus-Evoked Potentials From the Amygdala After Fear Conditioning in the Rat by J. M. J. Knippenberg, E. L. J. M. van Luijtelaar, J. H. R. Maes

“…Male Wistar rats were subjected to a differential Pavlovian fear conditioning procedure in which one of two tones (6 or 10 kHz) was followed by an electric shock (CS+) and the other was not (CS-). …”
Get full text

Development, Characterization, and Pharmacodynamic Evaluation of Hydrochlorothiazide Loaded Self-Nanoemulsifying Drug Delivery Systems by Pankajkumar S. Yadav, Ekta Yadav, Amita Verma, Saima Amin

“…In vivo pharmacodynamic evaluation in Wistar rats showed considerable increase in pharmacological effect of HCT by SNEDDS formulation as compared with plain HCT.…”
Get full text

Pluriactividad del trabajo femenino: recurrencias y transiciones. Un estudio de caso en Tlaxcala, México by Janett Vallejo Román, Juan Carlos Rodríguez Torrent

“…En el contexto de globalización neoliberal se aprecia una redirección y decantación de las mujeres al mercado del trabajo en los espacios rurales, poniendo de manifiesto: a) la necesidad de incorporación de más miembros del grupo doméstico en la búsqueda de ingresos, b) la multiplicación de sus jornadas de trabajo, c) prácticas poco justas y equitativas dentro y fuera del hogar con respecto al trabajo, y d) mayor tensión entre los miembros del hogar en el momento de la toma de decisiones respecto al trabajo fuera del hogar por parte de éstas. …”
Get full text

Los hijos e hijas y la percepción de pobreza en hogares caleños by Maribel Castillo, Geovanny Castro, Oscar Andrés González

“…Como los hogares que decidieron dejar a sus hijos e hijas menores de 5 años al cuidado de una persona adulta lo hicieron motivados por generar mayores ingresos, recomendamos el fortalecimiento de políticas que permitan mejorarlos, sin restar el tiempo que deben dedicarle a sus hijos e hijas.…”
Get full text

Fiber isolated from discarded fruits and vegetables reduces valproic acid-induced hepatotoxicity in rats by Maria Rosana Ramirez, Debora Manuale, Juan Carlos Yori

“…Subsequently, its potential protective effect against hepatotoxicity induced by valproic acid (VPA) was investigated in Wistar rats, both as preventive and curative treatments. …”
Get full text

Participación infantil como aproximación a la democracia: desafíos de la experiencia chilena by Daniela Díaz-Bórquez, Nicolás Contreras-Shats, Natalia Bozo-Carrillo

“…A partir de estándares establecidos por Save the Children, este estudio analiza la calidad de la participación infantil explorando percepciones de 299 profesionales vinculados al mundo de la niñez en todo Chile, y reflexionando respecto de los alcances y limitaciones de la participación infantil como expresión democrática, en un país que ha demorado 26 años en ajustar su legislación e institucionalidad a la Convención de los Derechos del Niño. …”
Get full text

Few-Shot Contrail Segmentation in Remote Sensing Imagery With Loss Function in Hough Space by Junzi Sun, Esther Roosenbrand

Get full text

Rosuvastatin, Sildenafil and Their Combination in Monocrotaline-Induced Pulmonary Hypertension in Rat by Jasińska-Stroschein Magdalena, Owczarek Jacek, Wesołowska Anna, Orszulak-Michalak Daria

“…Seven days after pulmonary hypertension induction, hydrophilic rosuvastatin and sildenafil were given for 14 days to male Wistar outbred rats. Right ventricular pressure, right ventricle mass and three biomarkers were evaluated after 21 days: brain natriuretic peptide, high-density lipoprotein cholesterol and vascular endothelial growth factor. …”
Get full text