不同病毒载量的乙型肝炎病毒在不同ALT状态下对肝星状细胞增殖、细胞周期及细胞分泌的影响 by 高鹏, 刘才周, 朱陇东, 李俊峰, 于海涛, 姚立琼

“…而在ALT异常状态下，特别是 ALT ≥2UNL组中，随着病毒载量的增加，HSC增殖加速，处于G0/G1期的明显减少，而处于S期，G2/M期的明显增多以及<italic>TGF-β1、Smad3、Collagen Ⅰ、Collagen Ⅲ、α-SMA</italic> mRNA及相应蛋白的表达明显增高，<italic>Smad7 </italic>mRNA及蛋白明显减少，差异有统计学意义。…”
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变应性鼻炎患者血浆细胞外囊泡对树突状细胞和巨噬细胞的调控作用 by 方淑斌, 付清玲

“…用AR-EVs刺激Mφ 2天后，PCR显示Mφ中IL-6（<italic>P</italic>＜0.001）和TNF-α（<italic>P</italic>＜0.05）的表达水平显著下降，TGM2的表达水平显著上升（<italic>P</italic>＜0.05），而MRC1和IL-10的表达水平则无显著变化。…”
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Analysis of Gait and Foot Pressure in Patients with Different Severity of Knee Osteoarthritis by LING Xingjin, OU Jianlin, XIE Wenhao, CHEN Zhuoming, OUYANG Hui

“…The peak plantar pressure points included the toe area, metatarsal area, medial area, lateral area, medial heel area and lateral heel area.ResultsAmong the spatiotemporal parameters of gait measured in both groups, stride length, stride speed, stride frequency, single support phase time, single support phase percentage, and swing phase time were smaller in the medium-severe group than in the mild group (<italic>P</italic>&lt;0.05), while stride time, stride width, double support phase time, and double support phase percentage were larger than in the mild group (<italic>P</italic>&lt;0.05). …”
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Effects of Neural Stem Cells combine with Nerve Growth Factor Nanoparticles Transplantation in Alzheimer's Disease Transgenic Mice by Qing ZHU, Shuai SHAO, Nan HU, Yan CHEN

“…Thioflavine-T staining was used to detect the numbers of Aβ plaques in the hippocampus and cortex.Results:①After transplantation for four weeks, EGFP-positive NSC survived in the brain, migrated extensively to corpus callosum, cortex and deep hippocampus, and differentiated into neurons and glial cells, NSC in the combined group survived more than those in the NSC transplant group and showed more complex synaptic morphology.②The number of ChAT neurons in the basal forebrain of the NSC transplant group and the combined group increased significantly(<italic>P</italic>&lt;0.05), compared with the NSC transplant group, the gene expression of ChAT and Lhx8 in the combined group were increased significantly(<italic>P</italic>&lt;0.05).③The number of Aβ plaques in hippocampus and cortex of the NSC transplant group and the combined group didn't decreased significantly(<italic>P</italic>&gt;0.05).Conclusion:NSC combined with NGF nanoparticles transplantation could indirectly protect cholinergic neurons in the basal forebrain and the survival and maturation of transplanted NSC, and promote the gene expression of ChAT and Lhx8 in the basal forebrain, but could not reduce the number of Aβ plaques in the hippocampus and cortex.…”
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白细胞过滤器对红细悬液中血小板的去除效率 by 刘浩强, 彭琳, 林宇霆, 冯宝莹, 巴桑, 嘎玛格列, 陆英

“…结果四组红细胞悬液中过滤前血小板的计数分别为（286.5±62.34）×10⁹/L、（238.0±57.37）×10⁹/L、（193.6±56.21）×10⁹/L和（167.8±24.76）×10⁹/L，储存3周（<italic>P </italic>&lt;0.01）和4周（<italic>P</italic> &lt;0.0001）组血液中的血小板计数明显低于储存1周组。…”
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窄翼缘PEC中长柱轴压整体稳定性能试验研究 by 张文轩, 石韵, 苏明周, 兰寒枫, 庄向平, 蔡仁武

“…当试件的正则化长细比大于1.0，初始弯曲大于<italic>L</italic>/1 000时，试件的破坏模式表现为整体极值点失稳；当试件的正则化长细比大于1.0，初始弯曲小于<italic>L</italic>/ 2 000时，试件的破坏模式表现为弹性平衡分岔失稳；当试件的正则化长细比小于1.0，初始弯曲小于<italic>L</italic>/2 000时，试件的破坏模式介于弹塑性极值点失稳和平衡点分岔失稳之间；初始弯曲一致时，试件的极限承载力随着长细比的增大迅速降低。…”
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皮下注射巨噬细胞集落刺激因子诱导机械痛超敏的性别二态性 by 彭湘格, 林震嘉, 张辉, 冷世泽, 唐源, 郑钰凡, 谈智, 周利君

“…相应地，脊髓背角浅层的<italic>p</italic>-ERK与CGRP⁺末梢在M-CSF处理后显著增多，且雄性小鼠多于雌性小鼠。…”
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抗病毒治疗HIV/AIDS患者抑郁状况及其影响因素分析 by 袁欣, 徐园园, 朱正平, 张敏, 吴苏姝, 王静文, 王少康

“…结果本研究共收集有效问卷1 879份，抑郁检出率为50.1%，多因素logistic回归分析结果显示：相较于初中及以下文化程度的患者，研究生及以上文化程度抑郁的风险更低［OR=0.534，95%CI（0.341，0.835），<italic>P</italic>=0.006］；相较于抗病毒治疗时长&lt;1年，抗病毒治疗时长1~5年［OR=0.729，95%CI（0.536，0.991）］、&gt;5~10年［OR=0.516，95%CI（0.379，0.702）］、&gt;10年［OR=0.603，95%CI（0.375，0.969）］抑郁的风险更低；相较于中低社会支持水平，高社会支持水平是HIV/AIDS患者抑郁保护性因素［OR=0.430，95%CI（0.349，0.530），<italic>P</italic>＜0.001］；相较于未存在治疗药物副作用，存在药物副作用发生抑郁的风险更高［OR=2.260，95%CI（1.833，2.786），<italic>P</italic>＜0.001］；同时在HIV耻辱感量表得分越高，抑郁的可能性越高。…”
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Effect of Sling Exercise Therapy on Adolescent Patients with Idiopathic Non-double-curved Scoliosis by Wudong SUN, Qian CAI, Jianye GUO, Xiaorui SHANG, Xianghu ZHAO, Liang XU, Ming MA

“…Before treatment and after treatment for six months, Cobb angle was used to evaluate the severity of scoliosis; clavicular angle(CA)was used to evaluate the degree of shoulder imbalance; pelvic obliquity(PO)was used to evaluate the degree of pelvic imbalance; scoliosis research association-22 item questionnaire(SRS-22)was used to evaluate the patients'self-image satisfaction.Results:Before treatment, there were no significant differences in Cobb angle, CA, PO and SRS-22 scores between the two groups(<italic>P</italic>&gt;0.05).Compared with before treatment, Cobb angle, CA and PO in both groups were significantly decreased, and SRS-22 score was significantly increased, with statistical significance(<italic>P</italic>&lt;0.05).Compared with the control group, Cobb Angle, CA, PO in the observation group were lower, and SRS-22 score in the observation group was higher, with statistical significance(<italic>P</italic>&lt;0.05).Conclusion:The sling exercise therapy can effectively improve AIS patients'scoliosis, shoulder imbalance, pelvic imbalance and self-image satisfaction, which is worthy of clinical promotion.…”
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Assessment Standard for the International Classification of Functioning, Disability and Health Rehabilitation Set (I) by Tiebin YAN, Yan GAO, Malan ZHANG, Liming YOU

“…For further use utilization of the international classification of functioning, disability and health rehabilitation set, the expertise group combined literature research, based on relevant fundamental principles to formulate assessment standard for"<italic>the International Classification of Functioning, Disability and Health Rehabilitation Set</italic>".The standard consist of 30 categories including 9 body functions,14 activities,7 participations. …”
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Effect of Floating Needle Perfusion Therapy combined with Joint Mobilization on Shoulder Pain of Hemiplegia after Stroke by Xin WANG, Hu LI, Xiuyan LU

“…Before treatment and after treatment for four weeks, the visual analogue scale (VAS) was used to assess shoulder pain, the Fugl-Meyer assessment (FMA) was used to assess upper extremity motor function, the modified Barthel index (MBI) was used to assess activities of daily living, and the goniometer was used to measure the passive range of motion of the shoulder joint.Results:Before treatment, there were no significant differences in VAS scores, FMA scores, MBI scores and PROM of the shoulder joint in three groups, with no statistically significant differences (<italic>P</italic>&gt; 0.05). Compared with before treatment, the VAS score of the three groups after treatment for four weeks decreased significantly, while the FMA score, MBI score and PROM of the shoulder joint increased significantly, with statistically significant differences (<italic>P</italic>&lt; 0.05). …”
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静脉输注利多卡因对腹腔镜疝修补术患儿苏醒期躁动的临床观察 by 许冬妮, 刘婷, 王培宗, 卢桠楠

“…主要观察指标包括WATCHA量表躁动评分，拔管后躁动发生率，补救加药次数；次要观察指标包括术中平均七氟烷吸入浓度，术后早期疼痛评分，拔管时间，恢复室停留时间，48h内术后镇痛药物曲马多使用量，结果① D组、L组患儿术后WATCHA躁动评分均低于C组； D组、L组患儿躁动发生率分别为15%、20%，均低于C组70%；补救加药人次均为10%，低于C组55%；采用Bonferroni校正，两两对比差异有统计学意义 （<italic>P</italic>&lt;0.017）。② D组和L组患儿，术中平均七氟醚吸入浓度低于C组；L组拔管时间（12.05±2.96）min低于D组；恢复室停留时间（51.50±9.61）min最短，少于D组和C组，Bonferroni校正后两两对比，差异有统计学意义（<italic>P</italic>&lt;0.017）。…”
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圆钢管掺镍铁渣再生混凝土柱抗震性能及恢复力模型研究 by 罗才松, 许力, 陈华艳, 付朝江, 祁皑

“…试验结果表明，RFCFST柱的破坏模式与传统钢管混凝土柱相似。<italic>P</italic>-<italic>Δ</italic>效应会显著降低柱的抗侧能力和变形能力，尤其是在高轴压比和高剪跨比情况。…”
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癌相关成纤维细胞促进胃癌细胞迁移与侵袭 by 周畅, 陈伟强, 王宇恒, 杨晓夏, 涂幸, 刘靖, 罗利

“…结果我们成功分离培养NFs及CAFs；与NFs-CM 组相比，CAFs-CM组胃癌细胞的迁移与侵袭能力均增强（<italic>P</italic> &lt; 0.05），胃癌细胞形态由扁圆的上皮细胞形态演变为梭形的间质细胞形态，胃癌细胞中上皮细胞标志E-钙粘蛋白（E-cadherin）表达降低，间质细胞标志波形蛋白（Vimentin）和 N-钙粘蛋白（N-cadherin）表达上升（<italic>P</italic> &lt; 0.05）。…”
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Design and Performance Analysis of ISFET Using Various Oxide Materials for Biosensing Applications by Sankararao Majji, Asisa Kumar Panigrahy, Depuru Shobha Rani, Muralidhar Nayak Bhukya, Chandra Sekhar Dash

“…The results show that the ISFET possesses drain-induced barrier lowering (DIBL), greater ON-current <italic>(I_ON</italic>) and switching ratio (<italic>I_ON&#x002F;I_OFF</italic>), and decreased subthreshold swing (SS). …”
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薄壁型钢混凝土梁抗弯性能试验研究 by 任重, 张志鹏, 何逸鸣, 程亮, 戴柳丝

“…研究结果表明：TSC梁的失效模式为薄壁钢管加载点处发生局部屈曲，外围混凝土保护层出现贯通斜裂缝，混凝土保护层沿抗剪螺杆开裂；TSC梁试件在加载过程中未发生脆性破坏，表现出较好的延性；TSC梁开裂荷载较小，处于0.11<italic>P</italic>_u ~ 0.15<italic>P</italic>_u之间，裂缝总数较少，稳定在6~10条；满布螺杆、增大钢管截面、减小剪跨比以及增加保护层厚度均可提高TSC梁试件的承载力。…”
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Research on Role of Connexin 36 in Pathogenesis of Rats with Levodopa-induced Dyskinesia by Bingtian ZHANG, Zhibin CHEN, Xiaowu CHEN, Xiaokuo HE, Chao HAN

“…The behavioral changes in the experimental group and the control group were observed by abnormal involuntary movement (AIM) score, the Cx36 expression in the right striatum in the five groups were detected by immunohistochemisty, and the relationship between Cx36 expression and behavior was investigated.Results:The AIM scores in the experimental group was higher than that of the control group (<italic>P</italic>&lt;0.05); the expression of Cx36 in the injured side of striatum in the experimental group was higher than that of the other four groups (<italic>P</italic>&lt;0.01); and the Cx36 expression was positively related to AIM scores.Conclusion:The increase of Cx36 expression is closely related to the pathogenesis of LID. …”
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早期湿疹婴儿的气质特征研究 by 韦茹, 王静, 杨延萍, 肖玉联, 陈力, 谭美珍, 查彩慧

“…结果湿疹组与对照组气质类型总体分布比较，湿疹组男婴D型和I-D型明显高于对照组，E型和I-E型显著低于对照组（<italic>P</italic>＜0.001）；气质维度的单因素条件Logistic回归分析显示婴儿湿疹气质的影响因素有婴儿活动水平、节律性、适应性和反应强度四个维度（<italic>P</italic>＜0.05）；进一步气质维度的多因素条件Logistic回归分析（向后法）显示，适应性和反应强度两个维度为独立影响因素，湿疹组婴儿适应性较强、反应强度较弱。…”
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一例鸡尾鹦鹉鸟肠球菌感染的临床报道 by 黄潇航, 王海论, 彭佳佳, 李诗艺, 张龙, 贺金峪, 王诗晨, 黄志坚, 殷光文

“…为探究临床具有神经症状的宠物鸡尾鹦鹉（<italic>Nymphicus hollandicus</italic>）的死因，对 1只死亡鸡尾鹦鹉的心、肝、脾和肾等脏器进行病原菌分离纯化、革兰氏染色和生化鉴定，采用PCR方法对16S rRNA进行分子生物学鉴定，并对分离致病细菌进行体外药敏试验，采用RT-PCR方法检测NDV、IBV和CIAV。…”
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Anti-oxidative Effect of Complex Prescription Pien Tze Huang Gan Bao on Chemical Liver Injury by Jinming HUANG

Subjects: “…Pien Tze Huang Gan Bao…”
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