Effect of Lingnan Painless Apitherapy combined with McKenzie Therapy on Patients with Lumbar Disc Herniation by Hongbo WU, Xinghua CHEN, Ruike ZHANG, Qinglu LUO, Yongming CHENG

“…Objective:To observe the clinical efficacy of Lingnan painless apitherapy combined with McKenzie therapy on patients with lumbar disc herniation(LDH).Methods:A total of 80 patients with LDH who were treated in the department of rehabilitation medicine of the fifth affiliated hospital of Guangzhou medical university from February 2019 to June 2020 were randomly divided into the control group and the observation group according to the random number table method, with 40 cases in each group.The control group received magnetic thermal-vibration therapy and McKenzie therapy.The Japanese magnetic thermal-vibration therapy instrument(TM-3200)was used in the magnetic thermotherapy, the appropriate intensity(high, hot, warm and low temperature)was selected according to the patient's feeling and symptoms, 20 minutes each time, once a day, seven times a week, continuous treatment for two weeks.In addition, the patients with LDH received McKenzie therapy, which was assisted by the therapist or the patient actively completed the flowing training, such as prone position stretching, prone position stretching combined with compression, standing position lateral movement and so on.Each step rested for one minute, once every two days, continuous treatment for two weeks.The observation group received Lingnan painless apitherapy on the basis of treatment in the control group after half an hour's rest.Before treatment, the patients were given apitherapy tolerance test, performing apitherapy with one bee on each Zusanli acupoints on both sides.After apitherapy for 15 minutes, if there was no adverse reaction, the patients were given painless apitherapy with a quiet and comfortable environment, every other day.In this treatment, both sides of Huatuo Jiaji acupoints on the lumbar spinous processes were selected, and Huatuo Jiaji acupoints on both sides of the 5th lumbar spinous process were selected in the first treatment, one acupoint on the left and one on the right.After that, two acupoints were added each time, and each acupoint was treated by one bee.According to the order of Jiaji points on the 4th, 3rd, 2nd and 1st lumbar vertebrae, the number of bee needles increased to 10 bees.Before treatment and two weeks after treatment, visual analogue scales(VAS)was used to evaluate the pain degree, Oswestry disability index(ODI)was used to assess the lumbar spine dysfunction, and TCM syndrome score was used to evaluate the therapeutic effect, and the clinical efficacy was evaluated by <italic>the diagnosis and curative effect standards of TCM diseases</italic>.Results:Before treatment, there was no significant difference in the VAS score, ODI score and TCM syndrome score between the observation group and the control group(<italic>P</italic>&gt;0.05).Compared with treatment before, the VAS score, ODI score and TCM syndrome score after treatment for two weeks of the two groups were significantly reduced, with a statistically significant difference(<italic>P</italic>&lt;0.05).Compared with the control group, the VAS score and TCM syndrome score of the observation group were lower than those of the control group, with a statistically significant difference(<italic>P</italic>&lt;0.05), but there was no considerable difference in ODI score between the two groups(<italic>P</italic>&gt;0.05), and the clinical efficacy of the observation group(95%)was significantly higher than that of the control group(80%)(<italic>P</italic>&lt;0.05).Conclusion:Lingnan painless apitherapy combined with McKenzie therapy can significantly improve the pain degree and lumbar spine dysfunction of patients with LDH, which have a good effect and it is worthy of clinical promotion.However, it's necessary to develop large-sample randomized controlled trials and follow-up, to provide more reliable basis for clinical treatment of LDH.…”
Get full text

Mechanism of Delaying Cartilage Degeneration in Knee Osteoarthritis with Rongjin Niantong Recipe Based on lncRNA NEAT1 and Nrf2/ARE Pathway by FU Changlong, XIE Xinyu, QIU Zhiwei, HUANG Yanfeng, JIN Linglu, LI Xihai

“…Compared with the model group, the protein expression levels of Keap1 and iNOS in the Rongjin Niantong Recipe group significantly decreased (<italic>P</italic>&lt;0.05), while the protein expression levels of Nrf2, HO-1 and NQO-1 significantly increased (<italic>P</italic>&lt;0.05). 3) Expressions of lncRNA NEAT1 in cartilage: compared with the blank group, the expression level of lncRNA NEAT1 in the model group was significantly higher (<italic>P</italic>&lt;0.05); compared with the model group, the expression level of lncRNA NEAT1 in the Rongjin Niantong Recipe group significantly decreased (<italic>P</italic>&lt;0.05).ConclusionRongjin Niantong Recipe can delay cartilage degeneration in rats with osteoarthritis. …”
Get full text

BeatProfiler: Multimodal In Vitro Analysis of Cardiac Function Enables Machine Learning Classification of Diseases and Drugs by Youngbin Kim, Kunlun Wang, Roberta I. Lock, Trevor R. Nash, Sharon Fleischer, Bryan Z. Wang, Barry M. Fine, Gordana Vunjak-Novakovic

“…<italic>Goal:</italic> Contractile response and calcium handling are central to understanding cardiac function and physiology, yet existing methods of analysis to quantify these metrics are often time-consuming, prone to mistakes, or require specialized equipment&#x002F;license. …”
Get full text

Effect of Mirror Feedback Therapy of Contralaterally Controlled Functional Electrical Stimulation on Hand Function of Apoplectic Hemiplegic Patients by Yafei ZHOU, Qingzhen CHEN, Shihong HU, Yingying LI, Lei YU, Jiaran JIN

“…The differences were statistically significant (<italic>P</italic>&lt; 0.05). The U-FMA scores of the three groups were (25.85±8.38) in group A, (25.40±9.25) in group B and (27.20±9.21) in group C. …”
Get full text

双能CT用于房颤患者左心耳部血栓的诊断 by 赵君雅, 陈梦婷, 周旭辉, 余太慧

“…两组间性别、身体质量指数分布差异性无统计学意义（<italic>P</italic> &gt; 0.05）。LAAT/SEC 组CHA₂DS₂-VASC评分、左心房前后径大于非LAAT/SEC 组（<italic>P </italic>= 0.047；<italic>P </italic>&lt; 0.001）。…”
Get full text

Preliminary Clinical Study on Therapy of Lidocaine Local Block Combined with Acupuncture-rehabilitation in Treatment of Post-stroke Upper Limb Spasticity by Ji LI, Li ZHANG, Ying GUAN, Lu WANG, Guile XIN, Yanli XING, Qiang TANG

“…The MAS grade, FMA-UE, MBI, and AROM scores of the two groups improved significantly after treatment compared with those before treatment, as the differences were statistically significant(<italic>P</italic>&lt;0.01).In addition, MAS grade in the observation group exhibited a substantial improvement compared with the control group after treatment(<italic>P</italic>&lt;0.01). …”
Get full text

C反应蛋白和嗜酸性粒细胞百分比在青年输血不良反应危险因素分析中的作用 by 李楠, 张怡宇, 谢双锋, 黎燕玲

“…结果与对照组患者相比，观察组发生非溶血性发热反应（FNHTR）患者输血前CRP更高；观察组发生过敏性输血反应（ATR）患者输血前CRP更高，有输血史者占比更高，输血前EO%更低，差异有统计学意义（<italic>P</italic>＜0. 05）。输入不同血液品种对发生ATR和FNHTR具有差异性（<italic>P</italic>＜0. 05）。…”
Get full text

胰腺神经内分泌肿瘤CT征象与SSTR2、VEGFR2及MGMT表达的关系 by 李璐杰, 宋晨宇, 周小琦, 罗宴吉, 冯仕庭, 彭振鹏

“…回顾性分析pNENs的CT特征与SSTR2、VEGFR2及MGMT表达情况的相关性，采用独立样本<italic>t</italic>检验或非参数检验及ROC曲线进行分析。结果SSTR2（+）组及SSTR2（-）组在性别、边界的差异有统计学意义（<italic>P</italic>&lt;0.05），VEGFR2（+）组及VEGFR2（-）组在性别、最大径线≥20 cm、边界、强化率（动脉期、静脉期）及CT值比率（静脉期）的差异有统计学意义（<italic>P</italic>&lt;0.05），MGMT（+）组及MGMT（-）组在最大径线≥20 cm、最大径、边界、强化率（动脉期）及CT值比率（平扫、动脉期、静脉期）的差异有统计学意义（<italic>P</italic>&lt;0.05）。…”
Get full text

骨肉瘤细胞外泌体激活肺组织成纤维细胞炎性信号通路 by 谢显彪, 温丽丽, 吕东明, 李洪波, 刘伟海, 邹雨桐, 姚浩, 沈靖南

“…结果143B细胞外泌体中TSG101、Flotillin-1、CD63、CD9表达，Calnexin表达缺失(<italic>P</italic>&lt;0.05)；电镜外泌体呈“茶托”样形状，大小为(141.92±52.85) nm；外泌体经裸鼠尾静脉注射后进入肺组织含量显著高于肝、肾、脾、脑等器官（<italic>P</italic>&lt;0.05）；外泌体与人肺成纤维细胞共培养后炎性因子IL-1β、IL-6及TNF-α mRNA水平明显升高（<italic>P</italic>&lt;0.05），同时p-p65，p-ERK及p-p38均显著上调（<italic>P</italic>&lt;0.05）。…”
Get full text

高强钢组合K形偏心支撑结构的结构影响系数和位移放大系数研究 by 李慎, 王泽宇, 田建勃, 李晓蕾

“…耗能梁段在大震作用下剪切屈服耗散能量，而梁柱构件基本处于弹性受力状态，保证地震作用下的塑性变形仅集中于耗能梁段。结构影响系数<italic>R</italic>是基于性能的抗震设计方法中至关重要的部分，<italic>R</italic>取值合理是结构抗震性能设计的关键。…”
Get full text

喹吡罗诱导的慢性强迫症小鼠模型的改进 by 罗宇翀, 韦淳仁, 陈晓, 李沫演, 温盛霖

“…目的为了获得造模时间更短且症状维持时间更长的慢性强迫症小鼠模型，我们尝试对已有的喹吡罗诱导的慢性强迫症小鼠模型的造模方式进行优化。方法将22只小鼠随机分成实验组（<italic>n</italic>=11）和对照组（<italic>n</italic>=11），分别在其颈后皮下注射0.75 mg/kg的喹吡罗溶液或等量的生理盐水后放入强迫行为训练装置中训练，连续重复19 d，并记录两组小鼠训练期间的饮水行为及饮水量，评估喹吡罗对小鼠行为的影响。…”
Get full text

珠三角地区变应性鼻炎和/或支气管哮喘患者皮下特异性免疫治疗依从性的真实世界研究 by 江育蔺, 王心悦, 唐隽, 鲍燕敏, 王桂兰, 白珺, 廖振鹏, 黎雅婷

“…结果纳入1 244例接受SCIT的患者，中止治疗427例（脱落率为34.3%）；儿童、已婚、过敏家族史阳性、总IgE （tIgE）&gt;200 U/mL的患者表现出相对良好的SCIT依从性（<italic>P</italic>值均&lt;0.05），而单纯AR患者依从性较AR合并BA组低（<italic>P</italic>&lt;0.05），治疗前症状评分和药物评分高的患者脱落率低（<italic>P</italic>值均&lt;0.001）。…”
Get full text

术前中性粒细胞与淋巴细胞比在食管鳞癌中的预后意义 by 田界勇, 徐广文, 熊燃, 梅新宇

“…根据ROC曲线得出NLR最佳Cut-off值，根据最佳Cut-off值分为高NLR组和低NLR组，使用<italic>χ</italic>²检验比较两组患者临床病理特征。使用Kaplan Meier生存曲线和Cox比例风险模型研究NLR对食管癌预后的影响。…”
Get full text

Wearable Loop Sensors for Knee Flexion Monitoring: Dynamic Measurements on Human Subjects by Ian Anderson, Christopher Cosma, Yingzhe Zhang, Vigyanshu Mishra, Asimina Kiourti

“…<italic>Goals:</italic> We have recently introduced a new class of wearable loop sensors for joint flexion monitoring that overcomes limitations in the state-of-the-art. …”
Get full text

基于“心与小肠相表里”探讨阿尔茨海默病小鼠全肠道菌群移植对回肠肠道微环境的影响 by 熊伟, 胡林, 许青, 李熙, 丁贤, 窦重阳, 陈芳芳, 闫智勇

“…结果AD小鼠全肠道菌群移植到正常小鼠后，病理分析表明仅回肠组织出现粘膜层破坏和隐窝腺上皮细胞变性、坏死脱落；测序分析发现，仅回肠菌群的种类数量（<italic>P</italic>&lt;0.01）、Chao1指数（<italic>P</italic>&lt;0.01）和Simpson指数（<italic>P</italic>&lt;0.01）降低且菌群组成和AD模型小鼠更相似。…”
Get full text

Effect of Electroacupuncture at Baihui and Shenting on Learning and Memory of Cerebral Ischemia-reperfusion Injuried Rats Via Magnetic Resonance Spectroscopy by Congkuai ZHAO, Weilin LIU, Ruhui LIN, Jing TAO

“…Morris water maze was used to evaluate learning and memory ability, T2-weighted imaging was used to assess the cerebral infarct volume, and magnetic resonance spectroscopy (MRS) was used to observe the nerve cell metabolism of hippocampus.Results:After seven days of EA treatment, the numbers of crossing platform of FCIR rats were significantly increased in Morris water maze (<italic>P</italic>&lt;0.01). The cerebral infarct volume of FCIR rats was decreased (<italic>P</italic>&lt;0.01). …”
Get full text

PCCN: Polarimetric Contexture Convolutional Network for PolSAR Image Super-Resolution by Lin-Yu Dai, Ming-Dian Li, Si-Wei Chen

“…The proposed PCCN method is trained with one <italic>X</italic>-band polarimetric and interferometric synthetic aperture radar (PiSAR) data, while evaluated with the same scene but different PiSAR imaging direction and with different sensors data including the <italic>C</italic>-band Radarsat-2 and the <italic>X</italic>-band COSMO-SkyMed of various imaging scenes. …”
Get full text

北京首都国际机场鸟击物种鉴定及防控建议 by 王业, 李壹, 徐静, 罗伏兵, 何宏轩

“…收集2020年5月—2021年4月北京首都国际机场的鸟击残留物，使用DNA条形码技术对138份鸟击残留物进行鉴定，共鉴定出61个物种。分析发现：鸟击物种以云雀（<italic>Alauda arvensis</italic>）、金腰燕（<italic>Cecropis daurica</italic>）和红胁蓝尾鸲（<italic>Tarsiger cyanurus</italic>）等小型鸟为主；雀形目（Passeriformes）发生鸟击的次数最多，占鸟击总次数的74.64%。…”
Get full text

Feasibility Study of Swallowing Assistive Gel during Capsule Swallowing in Post-Stroke Patients by Videofluoroscopic Swallowing by Meng DAI, Delian AN, Ke ZHANG, Yaowen ZHANG, Zulin DOU

“…We analyzed quantitative parameters included oral transit time (OTT), stage transition time (STT), pharyngeal transit time (PTT), UES opening time (UOT), delay time (DT), hyoid bone superior movement (HSM), hyoid bone anterior movement (HAM) and UES opening diameter (UOD).Results:Successful swallowing ratio was 80.65%by using SAG, which was significantly higher than 54.84%by using water (χ²=4.724, <italic>P</italic>=0.030). Oral transit time of taking capsules with SAG(3 688.2±3 370.6) ms tended to be longer (<italic>P</italic>&lt; 0.05) than water (1 886.2±1 467.4) ms, while HSM tended to be larger (<italic>P</italic>&lt; 0.05) by using water (15.61±5.59) mm than by using SAG(11.74±4.94) mm.Conclusion:With the advantages in lubrication and smoothness, SAG can ease capsule swallowing in post-stroke patients and bring safety as well. …”
Get full text

AppAuth: Authorship Attribution for Android App Clones by Guoai Xu, Chengpeng Zhang, Bowen Sun, Xinyu Yang, Yanhui Guo, Chengze Li, Haoyu Wang

“…However, there still remains one open challenge that has not been well addressed in previous work, <italic>i.e.</italic>, <italic>the authorship attribution for the detected app clones</italic>. …”
Get full text