Mechanism of Electroacupuncture on Neuropathic Pain via Regulation of CD137L in Hippocampal Glia by ZHENG Changyue, LAN Yanyan, HUANG Qiuling, JIANG Menghong, WANG Zhifu

“…Immunofluorescence was used for the cellular localization of CD137L and receptor CD137, and to measure the Iba-1 and GFAP expression in hippocampal CA1 region.Results1) Compared with the sham operation group, mechanical pain threshold and new object recognition index in the model group significantly decreased (<italic>P</italic>&lt;0.01); compared with the model group, mechanical pain threshold and new object recognition index in the electroacupuncture group significantly increased (<italic>P</italic>&lt;0.01). 2) Compared with the sham operation group, the concentrations of CD137L, Iba-1, GFAP and TNF-α in hippocampus of rats in the model group significantly increased (<italic>P</italic>&lt;0.01), and the number of positive Iba-1 and GFAP immune reactions significantly increased (<italic>P</italic>&lt;0.01); compared with the model group, the concentrations of CD137L, Iba-1, GFAP and TNF-α in hippocampus of rats in the electroacupuncture group significantly decreased (all <italic>P</italic>&lt;0.05), and the number of positive immune reactions of Iba-1 and GFAP significantly decreased (all <italic>P</italic>&lt;0.01). 3) Immunofluorescence detection showed that CD137L and its receptor CD137 were significantly co-expressed with microglia marker (Iba-1) and astrocyte marker (GFAP) in hippocampal CA1 region, suggesting that CD137L and CD137 were mainly expressed in microglia and astrocytes, but not in neurons.ConclusionElectroacupuncture may play an analgesic role by reducing the expression of glial CD137L, the amount of activated glial cells and the concentrations of TNF-α.…”
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Effect of Jin's Three-Needle Therapy Combined with Behavioral Intervention on Preschool Children with Mild-to-Moderate Autism Spectrum Disorder by HONG Yu, KANG Jie, GUO Jingmin, LIU Guihua, OU Ping, CHEN Xiaofang, HUANG Longsheng

“…Compared with the control group, the social cognition score, social communication score, social motivation score, autism behavior style score and SRS total score in the observation group significantly decreased after treatment (<italic>P</italic>&lt;0.05). (3) Anxiety disorder score: compared with before the treatment, the scores of fear of physical injury, social anxiety and generalized anxiety in the control group decreased significantly after treatment (<italic>P</italic>&lt;0.05), while the total score of SCAS and the scores of each factor of SCAS in the observation group decreased significantly after treatment (<italic>P</italic>&lt;0.05).ConclusionJin's three-needle therapy combined with behavioral intervention can alleviate the core symptoms of preschool children with mild-to-moderate ASD, and improve their social communication skills and their anxiety disorders, which is worthy of clinical application.…”
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荜茇酰胺通过诱导口腔鳞癌细胞自噬抑制增殖 by 许小鸿, 郅程, 袁忠民

“…结果与对照组比较，荜茇酰胺显著抑制Cal27及UM1细胞株增殖能力，呈浓度及时间依赖性（<italic>P</italic>&lt;0.05）；Western blot结果显示，不同浓度（1.0、3.0和5.0 μmol/L）荜茇酰胺处理细胞均使LC-I、LC3-Ⅱ表达水平显著高于对照组（<italic>P</italic>&lt;0.05），而Beclin1和p62表达低于对照组（<italic>P</italic>&lt;0.05）；荜茇酰胺处理组中p-mTOR和p-S6磷酸化水平显著低于对照组（<italic>P</italic>&lt;0.05）；与单独荜茇酰胺处理比较，3-MA和荜茇酰胺共处理使胞内LC3-I和LC3-Ⅱ表达水平明显下降，p62表达升高（<italic>P</italic>&lt;0.05），但BAFA1和荜茇酰胺共处理使细胞内p62表达升高（<italic>P</italic>&lt;0.05），LC3-Ⅱ表达水平无明显改变；3-MA和B AFA1处理都能拮抗荜茇酰胺对细胞活力的抑制效应。…”
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Effect of Music Therapy Combined with Rehabilitation Training on Reducing the Fall Risk in Elderly Patients with Multimorbidity by CHEN Xiaoya, YU Nannan, DING Jiajia, GUO Shanshan, DONG Hongsheng, DING Yuqing, ZHONG Na

“…Compared with that before treatment, the result of the 10MWT in the treatment group increased significantly (<italic>P</italic>&lt;0.05). Compared with the control group, the 10MWT result of the treatment group was significantly better (<italic>P</italic>&lt;0.05). …”
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Effect of High Frequency Repetitive Transcranial Magnetic Stimulation on Depression after Cerebral Infarction by JIANG Linlin, NIU Lingchuan, WANG Yule, YANG Baotong, LI Hao, LI Jiani

“…Compared with the control group, the MoCA scores and subitem scores of MoCA (such as attention/calculation and delayed memory) of the observation group were significantly higher (<italic>P</italic>&lt;0.05), and HAMD score and P300 latency were significantly lower, the difference was statistically significant (<italic>P</italic>&lt;0.05). …”
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IVF-ET周期中胚胎污染的实验室与临床结局分析 by 杜凤娇, 李瑞岐, 朱玉琴, 欧阳能勇, 区颂邦, 王文军

“…结果在29 583个周期中共出现70例胚胎污染（0.24%），所有污染均为体外受精（IVF）来源的胚胎而非卵胞浆内单精子注射（ICSI）来源的胚胎；在体外培养不同天数中，D2污染发现率最高（54.3%），其次是D1（32.9%）和D3（12.9%）；与卵泡液相比，精液是导致D1-D3污染发现的主要原因；卵泡液的主要污染源是粪肠球菌（18.0%），精液和培养液的主要污染源是大肠杆菌（59.6%， 66.7%），同时有5例污染周期的培养液中出现与卵泡液、精液均不一致的细菌类型；与全污染组相比，部分污染组的无可用胚胎周期率显著性降低（6/28 <italic>vs. </italic>34/42， 21.4% <italic>vs</italic>. 81.0%， <italic>P </italic>&lt; 0.001），囊胚形成周期率有升高趋势（5/12 <italic>vs.…”
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血浆ADAMTS-13活性和NLR在急性肺血栓栓塞症中的诊断价值 by 胡子旋, 何婉媚, 曾勉

“…结果健康对照组与急性PTE组ADAMTS-13活性水平分别为83.8%（72.2%， 98.8%）、63.3%（49.6%， 74.8%），vWF活性水平分别为102.7%（89.7%， 117.2%）、122.6%（96.8%， 156.6%），组间差异均具有统计学意义（<italic>P</italic>＜0.05），ADAMTS-13活性与vWF活性、D-二聚体水平呈负线性相关（<italic>P</italic>＜0.05）。…”
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Effect of Extracorporeal Shock Wave combined with Rehabilitation Training on Patients with Chondromalacia Patellae by Yanna ZHU, Yupeng LIU, Xiaoyi FAN, Chunling LIU, Hui YU, Xin QI, Shunji SHEN

“…Objective:To observe the clinical effect of extracorporeal shock wave combined with rehabilitation training on patients with chondromalacia patellae (CP).Methods:Sixty patients with CP were treated in Weihaiwei People's Hospital were randomly divided into the control group (<italic>n</italic>=20), the shock wave group (<italic>n</italic>=20) and the combined group (<italic>n</italic>=20). …”
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异体真皮基质与自体耳屏软骨-软骨膜在鼓膜修补中临床研究分析 by 王博琛, 刘彩鹏, 陈炯垣, 刘振

“…结果两组术后鼓膜愈合率均为100%，差异无统计学意义（<italic>P</italic>&gt;0.05）。术后可见表面血管爬生时间A组为（3.74±1.05）周，B组为（2.22±0.42）周，B组血管爬生更快，且两组之间差异有统计学意义（<italic>t</italic>=6.70，<italic>P</italic>&lt;0.01）；鼓膜上皮化时间A组为（5.35±0.98）周；B组为（4.00±0.53）周，2组上皮化更快，且两组之间差异无统计学意义（<italic>t</italic>=6.19，<italic>P</italic>&lt;0.01）。…”
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产后腹直肌分离的相关危险因素分析 by 李玲, 崔金晖, 欧阳丽萍, 孟召然, 范建辉

“…</italic> 26.8%和41.3% <italic>vs.</italic> 19.6%，<italic> P </italic>&lt;0.001）。…”
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基于贝叶斯权重估计方法的两栖动物多样性分析——以广东粤北华南虎省级自然保护区为例 by 康桐铭, 谢和平, 李文, 周阳阳, 张新旺, 蒋磊, 钟文勇

“…调查到的两栖动物包括国家二级重点保护野生动物1种（虎纹蛙<italic>Hoplobatrachus chinensis</italic>），广东省重点保护陆生野生动物4种（福建掌突蟾<italic>Paramegophrys liui</italic>、浦式短腿蟾 <italic>Brachytarsophrys popei</italic>、东方短腿蟾<italic>Brachytarsophrys orientalis</italic>、莽山刘角蟾<italic>Liuophrys mangshanensis</italic>）。…”
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Exploring the Functional Brain Activity of Motor Control of Abdominal Muscle Associated with Voluntary Voiding Based on Functional Near-Infrared Spectroscopy by SHI Yinshuang, WANG Menghuan, PAN Yingying, LIN Feng

“…Brain activity under the corresponding no-abdominal muscle-contraction task was used as a baseline to analyze the cortical activities specific to abdominal muscle contractions in these two different states.ResultsAbdominal muscle contractions during the strong desire to urinate primarily activated the bilateral pre-motor/supplementary motor area (BA6), bilateral dorsolateral prefrontal cortex (BA9/46), bilateral frontal pole area (BA10), the anterior portion of the right inferior frontal gyrus (BA47), the right middle temporal gyrus (BA21), the right primary motor cortex (BA4), and the left primary somatosensory cortex (BA1/2/3) in conjunction with the left inferior frontal of pars triangularis Broca's area (BA45) (<italic>P</italic>&lt;0.05). In contrast, abdominal muscle contractions with no desire to urinate primarily activated the bilateral pre-motor/supplementary motor area (BA6) (<italic>P</italic>&lt;0.05), the right primary motor cortex (BA4), the right primary somatosensory cortex (BA1/2/3), the right inferior frontal of pars triangularis Broca's area (BA45), and the right supramarginal gyrus part of Wernicke's area (BA40) (<italic>P</italic>&lt;0.05). …”
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Remote Sensing of Sun-Induced Fluorescence in a Deep Lake: Disentangling Quenching Mechanisms Improves Relationship With Chlorophyll-a Concentration Estimates by Remika S. Gupana, Daniel Odermatt, Abolfazl Irani Rahaghi, Camille Minaudo, Mortimer Werther, Claudia Giardino, Alexander Damm

“…It increases strongly when comparing PQ (<italic>R</italic>² &#x003D; 0.72 and MAPD &#x003D; 49&#x0025;) and NPQ cases (<italic>R</italic>² &#x003D; 0.48 and MAPD &#x003D; 68&#x0025;) separately. …”
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Biomechanical Gait Analysis in Children with Spastic Cerebral Palsy Using Foot Sole Model by ZHANG Qi, TOLENTINO Janel, SUN Chengyan, SHENG Bo, ZHANG Yanxin

“…The distance between the center of pressure and the origin of foot sole coordinate system, and the ankle and knee lever arms and external moments in AP and ML directions at maximal propulsion were also compared among three groups.Results(1) Characteristics of plantar center of pressure progression: compared with the normal developing group, COP-AJC₀ significantly increased in the equinus gait group and the crouch gait group (<italic>P</italic>&lt;0.05). Compared with the equinus gait group, the crouch gait group had an increased COP-AJC₀, a greater anterioposterior displacement, and a lower center of pressure displacement slope (<italic>P</italic>&lt;0.05). (2) The ankle and knee lever arms and external moments: compared with the normal developing group, the crouch gait group and the equinus gait group had longer anteroposterior lever arms around the knee and ankle joints (<italic>P</italic>&lt;0.05). …”
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单纯口服地屈孕酮在自然周期冻融胚胎移植中的临床疗效 by 冯书梅, 潘萍, 黄佳, 李予

“…根据不同黄体支持方案分为三组：A组单纯口服地屈孕酮片（<italic>n</italic>=524），B组阴道用黄体酮软胶囊（<italic>n</italic>=401），C组A+B联合用药（<italic>n</italic>=605），比较三种黄体支持患者的临床结局和成本-效果比。…”
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主动脉瓣狭窄对升主动脉瘤流场特征的影响 by 李昊天, 吕磊, 杨淞然, 华平

“…结果主动脉瓣狭窄组升主动脉的SSR（191.70 ［117.22~248.78］ s^-1）和WSS（2.87 ［1.88~4.00］ Pa）与非狭窄组的SSR（93.23 ［68.59~145.35］ s^-1）和WSS（1.20 ［1.04~2.18］ Pa）相比，差异具有统计学意义 （SSR： <italic>Z</italic> = 2.167， <italic>P</italic> = 0.030； WSS： <italic>Z</italic> = 2.233， <italic>P</italic> = 0.026），且差异主要表现在升主动脉近端及小弯侧 （<italic>P </italic>&lt;0.05）。…”
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Effect of Meridian Scraping Therapy Combined with Rehabilitation Training on sEMG and Dynamics of Upper Limb of Hemiplegic Stroke by Zhiqiang HUANG, Ning ZHAO, Zhaoyuan SU, Jiafu SU, Qiang WU

“…Modified Ashworth scale, range of elbow joint motion and Fugl-Meyer assessment were applied to evaluate biceps brachii muscle tonus changes of spastic upper limb when the affected elbow flexion, range changes of elbow joint motion and recovery of motor function.Results:After the treatment, the elbow flexion and extension torque of both groups were higher than those before (<italic>P</italic>&lt;0.05), and the co-contraction ratio was lower than that before (<italic>P</italic>&lt;0.05). …”
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Converting the Functional Independence Measures (FIM)-motor Scores to Modified Barthel Index (MBI) Scores —A Data Mining Approach by WONG Lik-hang Gary, WONG Kam-man Simon, NG Hin-Po Bobby

“…Using the data from subset (B) we found the Cohen's <italic>Kappa</italic> coefficients (k) for either "single-pair" items or "multiple-pair" items ranged from 0.770 to 0.913 — which indicated "substantial" to "almost perfect" agreement between the rated MBI scores and the derived MBI scores.ConclusionA "user-friendly" and yet methodologically sound conversion method is recommended for application in stroke rehabilitation program.…”
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Evaluating Curative Effects of Different Moxibustion Temperatures on Patients with Spastic Hemiplegia after Stroke by Liu YANG, Haili MA, Li GE, Qiaojing LIAO, Qiong HAN, Ling YE

“…Comparison of two groups showed that the major effects of time were statistically different (<italic>P</italic>&lt;0.05), but the major effects of intervention with no significant different (<italic>P</italic>&gt;0.05).After four treatments, two groups of motor function, daily life ability were greater than the corresponding minimum clinically important difference, with statistical significance (<italic>P</italic>&lt;0.05), thermal burning groups was more obvious.Conclusion:Different moxibustion temperature has a certain therapeutic effect on limb paralysis in patients with stroke, which can improve physical paralysis effectively, improve motor function and daily life ability, the thermal burning group is superior to the temperature-sensing group, and with low incidence of adverse events is low.…”
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DDTs沿扎龙湿地典型食物网的传递与富集规律 by 罗金明, 高忠燕, 李洪影

“…使用逸度模型模拟有机氯农药DDTs沿扎龙湿地典型食物网的传递和富集特征，评估环境中残留的DDTs对丹顶鹤（<italic>Grus japonensis</italic>）等大型水禽带来的潜在生态风险水平。结果表明：扎龙湿地生物的逸度比值与物种的营养位呈显著正相关（<italic>p</italic>=0.001），大型水禽与其食物之间的逸度比值较高，绿头鸭（<italic>Anas platyrhynchos</italic>）的逸度比值达到6.33，丹顶鹤及东方白鹳（<italic>Ciconia boyciana</italic>）的逸度比值分别高达13.17和14.55。…”
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