Effect of Shangke Zhitong Ointment Kinesio Tape on Ankle Sprain by WANG Qiang, LIU Zhiyang, JU Shaohua, LI Xiaodong, HUANG Jichao, XIANG Ning

“…Compared with the control group, serum IL-1β, TNF-α, MDA, FGF-2 and MMP-9 in the combined group were significantly lower after treatment (<italic>P</italic>&lt;0.05); serum IL-1β, TNF-α, MDA, FGF-2, TGF-β1, MMP-9 in the Shangke kinesio tape group were significantly lower after treatment, SOD was significantly higher (<italic>P</italic>&lt;0.05). …”
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Treatment Efficacy of Open Kinetic Chain Combined with Closed Kinetic Chain Exercise Training on Patients after Anterior Cruciate Ligament Reconstruction by GAO Peng, JIANG Xin, WANG Junzhe, WANG Hongyu, LIU Chengyao

“…Before and after intervention, Lysholm score and the international knee documentation committee (IKDC) score were used to evaluate the function of the affected knee, the KT-1000 score of the knee ligament and the differences of bilateral active range and passive range of motions; the ratio of jump distance between the affected side and the healthy side during one foot jump and cross foot jump were used to evaluate the lower limb motor function; Fugl-Meyer balance scale and Berg balance scale (BBS) were used to evaluate the balance function; isokinetic muscle strength testing system was used to analyze peak torque (PT), average power (AP), total power (TW) and atrophy index of quadriceps femoris on the affected side.Results(1) Knee motor function: compared with that before intervention, Lysholm and IKDC scores in four groups after intervention increased significantly, and KT-1000 score, bilateral active and passive joint motion differences decreased significantly (<italic>P</italic>&lt;0.05). Compared with the OKC group, the Lysholm score in the CKC group after intervention was significantly higher, the IKDC scores were significantly higher in the CKC group and adjusted combination group after intervention, and the KT-1000 score, bilateral active and passive joint motion differences were significantly lower (<italic>P</italic>&lt;0.05); the difference of bilateral active joint motion in the equal combination group significantly decreased (<italic>P</italic>&lt;0.05). (2) Balance function: compared with that before intervention, Fugl-Meyer score and BBS score in four groups after intervention were significantly higher (<italic>P</italic>&lt;0.05); there were no significant differences in Fugl-Meyer score and BBS score in four groups after intervention (<italic>P</italic>&gt;0.05). (3) Lower limb motor function: compared with that before intervention, the ratio of jump distance between the affected side and the healthy side during one foot jump and cross foot jump in four groups after intervention significantly increased (<italic>P</italic>&lt;0.05); compared with the OKC group, the ratio of jump distance between the affected side and the healthy side during one foot jump and cross foot jump in the CKC group and the adjusted combination group after intervention significantly increased (<italic>P</italic>&lt;0.05). (4) Quadriceps isokinetic muscle strength and atrophy index: compared with that before intervention, PT, AP and TW scores in four groups after intervention were significantly higher and atrophy index was significantly lower (<italic>P</italic>&lt;0.05). …”
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冠心病临界病变患者残余胆固醇/高密度脂蛋白胆固醇比值水平与冠脉CT血流储备分数的相关性 by 吴祯, 税星, 吴震, 陈泽锋, 陈璘

“…FFRct以0.8为界，分为缺血组（FFRct≤0.8，<italic>N</italic>=108例）与非缺血组（FFRct＞0.8，<italic>N</italic>=111例）。…”
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RNA结合蛋白PTBP1与磷酸化-AXL共表达在骨肉瘤中的临床意义 by 李湘湘, 徐雯莉, 卢正宇, 何安芳, 王震, 刘妮, 乐雨婷, 彭挺生

“…结果GEO数据库分析结果显示PTBP1和AXL在骨肉瘤组织的表达具有高于正常组织的趋势，但尚未达到统计学意义；Target数据分析结果显示PTBP1高表达组骨肉瘤患者总生存期（OS）与无进展生存期（PFS）均短于低表达组，但差异尚未达统计学意义（<italic>P</italic>=0.064； <italic>P</italic>=0.134）。…”
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Effect of Qing'e Formula on OPN, BSP and Integrin ɑ_vβ₃Expression in Bone Tissue of Ovariectomized Rats by Yuqing SUN, Wenjuan LUO, Bingqi WANG, Xiang CHEN, Xiaokang JIA, Yanping LIN

“…The Qing'e formula can suppress osteoclastic bone resorption by reducing the expression of bone tissue OPN, BSP and its receptor Itgɑ_v, Itgβ₃. …”
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Correlation Analysis of the Entorhinal Cortex-Hippocampus Nerve Fiber Changes and Memory Dysfunction in P301L-Tau Mouse Model and Molecular Mechanism by CHEN Xiaocheng, LIANG Shengxiang, LIN Bingbing, LIU Weilin, HUANG Jia

“…Pearson correlation analysis was used to analyze the correlation between fractional anisotropy (FA) values in different brain regions of the entorhinal cortex-hippocampus and their corresponding learning and memory functions.Results(1) Learning and memory function test: compared with the control group, the learning and memory function of the model group significantly decreased, the escape latency significantly increased, the number of platform crossings and time ratio of target quadrant significantly decreased (<italic>P</italic>&lt;0.05). (2) Structure of nerve fibers in the entorhinal cortex and hippocampus: compared with the control group, FA values of the entorhinal cortex and hippocampus in the model group decreased more significantly, MD values of the entorhinal cortex in the model group increased more significantly, while there was no significant difference in the MD values of the hippocampus in the model group (<italic>P</italic>&gt;0.05). (3) Correlation analysis between FA values in the entorhinal cortex-hippocampus and learning and memory function: FA values in the entorhinal cortex and hippocampus were positively correlated with the number of platform crossings (<italic>r</italic>=0.76, <italic>P</italic>&lt;0.05; <italic>r</italic>=0.62, <italic>P</italic>&lt;0.05). (4) Expression of t-Tau, Ser262 and GSK3β protein in the entorhinal cortex-hippocampus: compared with the control group, the expression of t-Tau, p-Tau (Ser262) and GSK3β protein of entorhinal cortex and hippocamp increased more significantly in the model group (<italic>P</italic>&lt;0.05).ConclusionThe Tau protein in the entorhinal cortex-hippocampus of the P301LTau mouse model was hyperphosphorylated, which leads to destruction of the nerve fiber structures in the entorhinal cortex-hippocampus and learning and memory dysfunctions. …”
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Effect of Graphene Warm Abduction Orthosis on Hip Joint Development in Children with Spastic Cerebral Palsy by CUI Meiyu, LIU Jianjun, ZHANG Yan, ZENG Fanyong

“…The d-MP [3.75 (0.09,10.61)] %, d-NAS (2.28±9.54)° and d-GMFM (-3.80±1.97) of the treatment group were compared with those of the control group [0.00 (-3.70,2.80)] %,(-7.90±8.63)°, (-2.14±1.60), the differences were statistically significant (<italic>P</italic>&lt;0.05), while the d-AI and d-MTS were not statistically significant (<italic>P</italic>&gt;0.05).ConclusionThe graphene warm abduction orthosis can effectively improve hip dislocation or subluxation in children with spastic cerebral palsy, delay its progression, and improve the gross motor function.…”
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辅酶Q₁₀抑制过氧化氢诱导的血小板线粒体功能紊乱 by 施译琳, 杨奥林, 王锐杰, 牙甫礼, 陈彦球, 杨燕

“…结果在静息血小板中，CoQ₁₀对线粒体功能无影响（线粒体膜电位、PS外翻阳性率、胞内ROS、mtROS、ATP水平，<italic>P </italic>&gt; 0.05）。在氧化应激模型中，H₂O₂使血小板线粒体膜电位下降、PS外翻增加，而CoQ₁₀可以显著逆转H₂O₂诱导的血小板线粒体膜电位下降［（35.76%±3.94）% <italic>vs</italic>. （21.04%±1.69）%，<italic>P </italic>&lt;0.05］，但对PS外翻无抑制作用（<italic>P </italic>&gt;0.05）。…”
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Effect of Swimming on Gut Microbiota and Inflammation in Colorectal Cancer Cells Transplanted Mice by LI Jiapeng, XIE Qiurong, WEN Ying, CHEN Haichun, PENG Jun, SHEN Aling

“…There was more biodiversity of intestinal flora in the swimming group than that in the model group (<italic>P</italic>&lt;0.05), with a significant difference in species classification from phylum, class, order, family and genus (<italic>P</italic>&lt;0.05). …”
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拮抗剂方案新鲜单囊胚移植患者妊娠失败的独立危险因素分析 by 周文, 刘瑜亮, 李涛, 邢卫杰, 张曦亚, 欧建平

“…结果两组患者间的基础资料差异无统计学意义，促性腺激素（Gn）使用天数（8.9±1.3 <italic>vs. </italic>8.6±1.2）、人绒毛膜促性腺激素（HCG）注射日的卵泡刺激素（FSH）水平（12.1±3.7 <italic>vs.…”
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齐齐哈尔百鸟湖鸭类空间分布及鸟击预防对策 by 张美琦, 严雪洁, 许青

“…结果表明： （1）全年记录鸭类18种，12 385只；鸭类优势种为绿头鸭（<italic>Anas</italic> <italic>platyrhynchos</italic>）、斑嘴鸭（<italic>A.zonorhyncha</italic>）、罗纹鸭（<italic>Mareca falcata</italic>）、赤膀鸭（<italic>M.strepera</italic>）、普通秋沙鸭（<italic>Mergus merganser</italic>）和红头潜鸭（<italic>Aythya ferina</italic>），数量占总数90%以上。…”
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YKL-40对特发性肺动脉高压患者预后的意义 by 易诗欣, 何洁欣, 陈果, 谭虹, 张莹

“…结果IPAH死亡组患者的血清YKL-40水平明显高于存活［95.3 （13.1~217.3） ng/mL <italic>vs.</italic> 11.0 （5.7~47.7） ng/mL，<italic>P</italic>=0.006］，三尖瓣环收缩期峰值速度（TAPSV）低于存活组［7（6.0~8.0） cm/s <italic>vs</italic>. 9 （7.0~11.0） cm/s，<italic>P</italic>=0.001］。…”
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基于简化基因组测序技术的喜马拉雅旱獭遗传多样性分析 by 李优, 南新营, 赵坤钰, 李耀东

“…为揭示喜马拉雅旱獭（<italic>Marmota himalayana</italic>）的遗传进化机制，基于双酶切RAD（dd-RAD）测序技术，对青海省3个地区（乐都、玉树、黄南）44例喜马拉雅旱獭简化基因组测序分析，通过SNP位点刻画其遗传特性，构建系统进化树，分析种群结构特征，从基因水平分析不同地区个体之间的遗传进化关系。…”
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基于熵权TOPSIS模型的中国候鸟疫病监测质量评价 by 李景浩, 秦思源, 孙贺廷

“…结果表明：2015—2022年，中国候鸟疫病监测综合评价、监测投入和监测成效整体上呈现增加趋势，2017年之前监测成效（<italic>T</italic>）小于0.3，质量水平偏低，2017年之后质量水平达到一般标准（0.3&lt;<italic>T</italic>&lt;0.6）；2015—2017年东部沿海和2015—2019年西部高山湿地区监测成效均小于0.3，质量水平偏低，其余年份质量水平一般（0.3&lt;<italic>T</italic>&lt;0.6）；2015—2022年，中部湖泊水网候鸟疫病监测成效质量水平一般（0.3&lt;<italic>T</italic>&lt;0.6）。…”
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白骨顶的种内巢寄生行为及对不同类型寄生卵的反应 by 赵紫寒, 渠畅, 杨月, 周永青, 宗诚, 程鲲

“…种内巢寄生是鸟类的条件性繁殖策略，具有特定的进化历史和地域特征。白骨顶（<italic>Fulica atra</italic>）作为古北界广泛分布的湿地水禽，其种内巢寄生和反寄生行为策略对于巢寄生理论假说的验证具有重要意义。…”
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膳食菊苣酸对过敏性哮喘小鼠的体内调节作用 by 李琴, 申云琴, 郭兴悦, 徐艺璇, 李灵杰, 武音帆, 杨燕, 陈彦球

“…结果与过敏性哮喘模型组相比，膳食菊苣酸干预组的体质量减轻现象和挠鼻症状明显改善（<italic>P</italic>&lt;0.05），外周血嗜酸性粒细胞数量、嗜酸性粒细胞/淋巴细胞比值显著下降（<italic>P</italic>&lt;0.05），肺部炎症浸润情况以及杯状细胞增生情况缓解（<italic>P</italic>&lt;0.05），肺组织Th2、Th17、Tc2、Tc17百分比降低（<italic>P</italic>&lt;0.001），Th1和Tc1百分比则没有变化（<italic>P</italic>&gt;0.05）。…”
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Research on Gear Profile Modification based on Thermal-fluid-solid Coupling by Yi Yangfan Lan Huiqing Yu Sitai

“…Then, when <italic>b</italic>=2, and when <italic>b</italic>=1.22，the modification show the best effect. …”
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Development of Wrist Rehabilitation Device based on Coaxial Spherical Parallel 3RRR Mechanism by Shuaixu Ji, Yongguo Liang, Huimin Hao, Li'na Li, Jiahai Huang

“…On this basis，the inverse kinematics mathematical model of the wrist rehabilitation device is established，and the relationship between the motor input angle and the output pose of the robot end is obtained，and the robot working space is determined，the maximum angle of rotation around the <italic>X</italic> axis is 32°，the maximum angle of rotation around the <italic>Y</italic> axis is 37°，and the full rotation around the <italic>Z</italic> axis. …”
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Mechanism of Bushen Huoxue Recipe on Improving Arterial Calcification in Rats with Osteoporosis Based on OPG/RANKL Signaling Pathway by LIN Xiaorong, YANG Na, ZHENG Bei, ZHAO Hu, XU Junxia

“…Compared with the osteoporosis group, the level of PⅠNP and BGP in the Bushen Huoxue group increased significantly (<italic>P</italic>&lt;0.05), and there was no significant difference in CTX-Ⅰ level (<italic>P</italic>&gt;0.05). 3) The expression level of OPG and RANKL protein in thoracic aorta: compared with the control group, the expression level of OPG in the osteoporosis group decreased significantly while the expression level of RANKL increased significantly, the difference was statistically significant (<italic>P</italic>&lt;0.05); compared with the osteoporosis group, the expression level of OPG protein in thoracic aorta of the Bushen Huoxue group increased significantly, and the expression level of RANKL protein decreased significantly, the difference was statistically significant (<italic>P</italic>&lt;0.05).ConclusionBushen Huoxue Recipe can improve BMD of osteoporosis rats, promote bone formation, and improve the condition of artery calcification induced by osteoporosis. …”
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Effect of Electroacupuncture on Chondrocyte Apoptosis in Knee Osteoarthritis Rat Based on PI3K/Akt Signaling Pathway by Yuanyuan ZHANG, Xinyu JIANG, Xihai LI, Mingxia WU

“…Compared with the model group, the cartilage morphology of the experimental group 1 and the experimental group 2 was neat, the number of chondrocytes was increased, the matrix staining was deepened, the tidal line was complete, Mankin's score was significantly decreased (<italic>P</italic>&lt; 0.01), the expressions of IL-1β and TNF-α in the synovium were significantly decreased (<italic>P</italic>&lt; 0.01), the expressions of PI3K, Akt and Bcl-2 mRNA and protein were significantly increased (<italic>P</italic>&lt; 0.01), and the expression of Bax mRNA and protein were significantly decreased (<italic>P</italic>&lt; 0.01). …”
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