Evaluation of Efficacy and Safety of Transdermal Electrical Stimulation in Treatment of Knee Osteoarthritis by Kaiming LI, Shangquan WANG, Linghui LI, Qing ZHANG, Long LIANG, Ming CHEN, Jiawen ZHAN, Jing YIN, Zhuo WANG

“…Meta-analysis results showed that the overall effective rate[<italic>RR</italic>=0.08, 95%<italic>CI</italic>(0.01, 0.61), <italic>P</italic>=0.02], visual analogue pain (VAS) score[<italic>MD</italic>=1.47, 95%<italic>CI</italic>(1.16, 1.77), <italic>P</italic>&lt; 0.001]and incidence of adverse reactions[<italic>RR</italic>=0.08, 95%<italic>CI</italic>(0.01, 0.61), <italic>P</italic>=0.02]in the experimental group were significantly better than those in the control group. …”
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不同反刍思维类型大学生对情绪面孔的注意偏向及时间进程 by 范熙, 李晓乐, 温煜煊, 杨子殷, 王辉

“…结果反应时指标显示，在负性-中性面孔对条件下，被试类型对注意偏向分数（BI）和注意脱离困难指数（DI）的影响均有统计学意义（<italic>F </italic>= 20.11，<italic>P</italic> &lt; 0.001， <italic>η</italic>²= 0.33）、（<italic>F</italic> = 11.46，<italic>P</italic> &lt; 0.001， <italic>η</italic>²= 0.22）。…”
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Pien Tze Huang Attenuates Neuro-inflammatory Injury in BV2 Microglial Cells Induced by Lipopolysaccharide via Inhibition of TLR4/MAPK Signaling Pathway by Zhenwei HUANG, Qing ZHANG, Lili HUANG, Xiaoqin ZHANG, Mingqing HUANG

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Effect of Suspension Massage Exercise Technique on Core Muscle Mass and Postural Control Ability of Patients with Stroke by SUN Jie, CHEN Guijuan, XU Han, ZHANG Tianyu, DING Yi, WANG Shurui, LI Li

“…Correlation analysis revealed that the PASS score was positively correlated with the MF value of the affected erector spinae muscle (<italic>r</italic>=0.404, <italic>P</italic>=0.030), and the PASS score was positively correlated with the MF value and iEMG value of the affected multifidus muscle (<italic>r</italic>=0.443, <italic>P</italic>=0.016; <italic>r</italic>=0.412, <italic>P</italic>=0.026), The PASS score was positively correlated with the MF value and iEMG value of the healthy multifidus muscle (<italic>r</italic>=0.728, <italic>P</italic>=0.000; <italic>r</italic>=0.407, <italic>P</italic>=0.028), and the postural transformation dimension score was positively correlated with the MF value of the healthy multifidus muscle and iEMG value of the affected multifidus muscle (<italic>r</italic>=0.609, <italic>P</italic>=0.000; <italic>r</italic>=0.381, <italic>P</italic>=0.042).ConclusionThe suspension massage exercise technique is effective for postural control disorders after stroke, improve the contraction efficiency and posture control ability of trunk core muscles, and reduce muscle fatigue, which is recommended for clinical application .…”
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外伸端板半刚性钢结构连接节点的弯矩-转角智能模型研究 by 刘坚, 肖海鹏, 刘长江, 张专涛, 王飞程, 马宏伟, 戚玉亮, 招渝, 彭林苗, 任达, 陈原, 童华炜

“…为了寻找一种耗费人力更少、预测效果更好的外伸端板半刚性钢结构连接节点的弯矩-转角（<italic>M</italic>-<italic>θ</italic>_r）关系模型，提出将智能模型引入对该种半刚性连接节点<italic>M</italic>-<italic>θ</italic>_r曲线的预测。…”
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三氧化二砷对T急淋白血病及DNA转甲基酶1的影响 by 苏嘉茵, 吴忠道, 罗学群

“…目的本研究旨在探索三氧化二砷（ATO）对急性T淋巴细胞白血病（T-ALL）细胞中DNA转甲基酶1（<italic>DNMT1</italic>）表达的影响及其抗白血病作用机制。方法体外培养T-ALL细胞株（Jurkat、CCRF-CEM、Molt-4），依据不同ATO干预浓度，分为对照组（0 μmol/L）、低浓度组（3 μmol/L）、高浓度组（6 μmol/L），应用RT-qPCR和western blot研究 ATO（0、3、6 μmol/L）干预24 h后细胞内<italic>DNMT1</italic>和<italic>cleaved-caspase-3</italic>表达的变化；应用流式细胞术测定 T-ALL 细胞系（Jurkat、CCRF-CEM、MOLT-4）的细胞死亡率；在ATO的干预下，应用Z-DEVD-FMK后检测<italic>DNMT1</italic>和<italic>cleaved-caspase-3</italic>表达和细胞死亡率的变化；在ATO的干预下，过表达<italic>DNMT1</italic>检测T-ALL细胞死亡率的变化。…”
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蓝孔雀肠道菌群中整合子及其水平转移相关性 by 陶芬, 张饶, 廖琦, 李芬仙, 刘垒成, 姜玉莎, 苗睿, 吴培福

“…为了解蓝孔雀（<italic>Pavo cristatus</italic>）肠道菌群中整合子及其基因盒的分布特征，以2个动物园蓝孔雀粪便为材料，采用CTAB法提取肠道菌群宏基因组DNA，共计139份；通过PCR法扩增整合子、基因盒，选取部分PCR产物测序。…”
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MG53蛋白对小鼠阿霉素急性心肌毒性的影响及机制 by 卢维哲, 刘海琼, 杨涵滟, 宋旭东, 陈爱华

“…采用小动物心脏超声分析小鼠心脏功能，观察左室射血分数、缩短分数的变化；通过qPCR技术分析心脏重构相关基因<italic>ANP、BNP、α-MHC</italic>，自噬相关基因<italic>Beclin1、LC3</italic>及凋亡基因<italic>CASPASE3</italic>的表达改变；采用免疫印迹技术检测自噬相关蛋白Beclin1、LC3及凋亡相关蛋白caspase3的表达水平；采用透射电镜观察心肌组织中的自噬小体；采用TUNEL试剂盒检测原代心肌细胞的凋亡水平。…”
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Emotions and Behaviors of Children Aged 0-6 during the Period of Epidemic Prevention at Home by Xuechang HE, Hui OUYANG, Hanzhang GUO, Zhuoming CHEN, Longbin SHEN, Jianlin OU

“…The only child [χ²=8.82, <italic>P</italic>=0.003, <italic>OR</italic>=11.10(2.27-54.40) ] and increased screen time [χ²=8.79, <italic>P</italic>=0.003, <italic>OR</italic>=5.80(1.81-18.53) ] were independent risk factor for children's mood swings. …”
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ANALYSIS OF THE CONSTRAINT EFFECT AND CREEP CRACK INITIATION TIME FOR STRUCTURE WITH ЕMBEDDED CRACKS by LI YuPeng, LI WenPeng, LI DingHe, WU DongQuan, WANG YuFeng, ZHENG YuXiang

“…The results revealed that the max value of constraint parameter was located at the end of major axis of elliptical crack, and the constraint levels enlarge with increasing the crack length or the crack depth, which meant that embedded cracks with a larger <italic>a</italic>/<italic>t</italic> or <italic>a</italic>/<italic>c</italic> would suffer from worse condition of stress concentration and there would be more dangerous. …”
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Systematic Review on Effect of Tai Chi Regarding to Glucolipid Metabolism and Life Quality of Type 2 Diabetes Mellitus by Yongjin LIU, Bo DU, Bowei HUANG, Liuqing YANG, Suping HUANG

“…The results of Metaanalysis demonstrated that Tai Chi exercise had positive effect on the levels of FBG [SMD=-0.39, 95%<italic>CI</italic> (-0.54, -0.24), <italic>P</italic>&lt;0.01], HbA1c [WMD=-0.59, 95%<italic>CI</italic> (-0.73, -0.44), <italic>P</italic>&lt;0.01], TG [SMD=-0.52, 95%<italic>CI</italic> (-0.85, -0.19), <italic>P</italic>&lt;0.01], HDL-C [SMD=0.31, 95%<italic>CI</italic> (0.14, 0.47), <italic>P</italic>&lt;0.01], LDL-C [WMD=-0.32, 95%<italic>CI</italic> (-0.59, -0.05), <italic>P</italic>&lt;0.05] and most items of quality of life; while there was no statistically significant on the levels of TC [SMD=-0.24, 95%<italic>CI</italic> (-0.58, 0.10), <italic>P</italic>&gt;0.05], physical function and body pain.Conclusion:Tai Chi exercise is effective to improve the levels of glucolipid metabolism and life quality of T2DM. …”
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Meta Analysis on Rehabilitation Effect of Proprioception Training on Ankle Sprainof Athletes by Yuxiao CHEN, Jiaojiao LIU, Changsong Yi, Mengguang CHAI, Qing WANG, Lei JIANG

“…Objective:To explore the effects of proprioception training on the incidence of athletes' ankle sprains, dynamic neuromuscular control, postural stability and joint position perception.Methods:Data were searched from the databases of PubMed, Cochrane Library, EMbase, China National Knowledge Infrastructure(CNKI), Wanfang Database(Wangfang Data), Chinese Journal Full-text Database(VIP), China Biomedical Literature Database(CBMdisc).Athletes were included in the randomized controlled trials(RCTs)who were treated with proprioception training to improve the function of athlete's ankle joint.The retrieval time for each database was from the establishment of the database to December 31, 2019, and the references of related documents were traced.Two researchers independently searchered the literature, extracted data, and evaluated the quality of the literature.RevMan5.3 software was used to analyze the data.According to the systematic review manual provided by the Cochrane Collaboration Network, the continuous variables use mean difference(<italic>MD</italic>)and 95%confidence interval(<italic>CI</italic>)as indicators, and binary variables use risk ratio(RR)and 95%<italic>CI</italic> as indicators.The statistical heterogeneity was judged comprehensively by chi-square test(χ²test)and the Heterogeneity test(<italic>I</italic>²test).If <italic>P</italic>≥0.1 and <italic>I</italic>²≤50%, a fixed effects model would be used.In contrast, if <italic>P</italic>&lt;0.1 or <italic>I</italic>²&gt;50%, a random effects model would be used.Results:A total of 11 RCTs and 1 776 athletes were included.The results of Meta analysis showed that compared with the control group, the incidence of ankle sprains in the experimental group was significantly reduced after proprioceptive training[<italic>RR</italic>=0.61, 95%<italic>CI</italic>(0.41, 0.90), <italic>P</italic>=0.01]; compared with the control group, the posterolateral and posterior medical maximum extension distances of the experimental group increased significantly after proprioception training[<italic>MD</italic>=4.44, 95%<italic>CI</italic>(3.66, 5.23), <italic>P</italic>&lt;0.00 001;<italic>MD</italic>=4.21, 95%<italic>CI</italic>(3.18, 5.24), <italic>P</italic>&lt;0.00 001]and the difference was statistically significant;but there was no significant difference in the improvement effect of the anterior maximum extension distance, and the difference was not statistically significant(<italic>P</italic>&gt;0.05).The postural sway of the affected ankle joint in the experimental group was significantly lower than that in the control group;the athletes in the experimental group had better position perception ability in the ankle joint plantar flexion, dorsiflexion, middle and lateral directions than the control group.Conclusion:Proprioceptive training can effectively reduce the incidence of athletes' ankle sprains, improve dynamic neuromuscular control, improve postural stability, and enhance ankle joint position perception, which is worthy of clinical application.However, the absolute effect is not yet clear, so large samples and high-quality randomized controlled trials are still needed to further verify the efficacy of proprioception training, so as to provide more reliable evidence-based evidence for clinical rehabilitation.…”
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补体系统C1q/C3介导的胶质细胞激活在小鼠抑郁样行为中的作用 by 王睿, 王清波, 谢婷, 郭开华

“…行为学测试系统悬尾实验（TST）、强迫游泳实验（FST）测试小鼠抑郁状态，采用免疫荧光染色法检测小鼠杏仁核中突触素（Syn）和突触后致密物（PSD95）变化情况，小胶质细胞（Iba-1）和星形胶质细胞（GFAP）细胞荧光强度，C1q、C3含量。② 6只8周<italic>CX3CR1-GFP</italic>雄性鼠，随机分为<italic>GFP</italic>组以及<italic>GFP</italic>模型（<italic>GFP</italic>+CRS）组，各3只，采用免疫荧光染色法观察小胶质细胞及星形胶质细胞相互作用情况。…”
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胆漏的位置可能是影响首次内镜逆行胰胆管造影术成功的相关因素 by 魏章均, 曹良启, 陈世荣

“…两组患者手术前后白细胞计数、肝功能及改善情况比较差异无统计学意义（<italic>P</italic>&gt;0.05）。把首次ERCP成功者分为A组（<italic>n</italic>=11），失败者为B组（<italic>n</italic>=8）。…”
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方中空夹层钢管混凝土叠合构件受弯性能试验研究与有限元分析 by 李明伦, 任庆新, 王庆贺, 丁纪楠

“…研究结果表明CECFDST构件具有良好的受弯性能，各部件间协同工作；剪跨比对构件受弯过程和受弯性能的影响不明显，受弯承载力变化不到4.5%；增大中空夹层钢管混凝土（CFDST）部件的含CFDST率<italic>D</italic>_o/<italic>B</italic>和名义含钢率<italic>α</italic>_n能够有效提高其力矩占比和强度发挥效率，外部配筋率<italic>ρ</italic>和<italic>α</italic>_n应分别与<italic>D</italic>_o/<italic>B</italic>保持正向和反向协调配置，建议0.50≤<italic>D</italic>_o/<italic>B</italic>≤0.75、0.25≤<italic>χ</italic>_n≤0.75、0.06≤<italic>α</italic>_n≤0.20。…”
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云南元阳哈尼梯田鸟类群落组成及季节动态分析 by 卜匀皓, 耿吉恒, 张健嵩, 段玉宝

“…结果显示：共记录到鸟类86种，隶属10目37科，其中包括国家二级重点保护野生动物4种，分别是褐翅鸦鹃（<italic>Centropus sinensis</italic>）、小鸦鹃（<italic>C.bengalensis</italic>）、普通鵟（<italic>Buteo japonicus</italic>）和红隼（<italic>Falco tinnunculus</italic>）；中国脊椎动物红色名录近危（NT）物种1种，即银耳相思鸟（<italic>Leiothrix argentauris</italic>）；数据缺乏（DD）1种，为蓝喉拟啄木鸟（<italic>Psilopogon asiatica</italic>）。…”
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乳酸脱氢酶A在肾细胞癌中的表达及意义 by 邱文瀚, 廖定准, 盛义雨, 熊海云, 李骏

“…目的分析乳酸脱氢酶A（<italic>LDHA</italic>）在肾细胞癌组织及细胞系中的表达情况并探讨其影响肾细胞癌细胞进展的方式。…”
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艾纳香油通过NF-κB非经典信号影响花生四烯酸代谢缓解LPS所致巨噬细胞的炎症反应 by 何贤芳, 王万林, 王鸿颖, 刘瑞秀, 易琼, 王鲁

“…方法采用豚鼠离体回肠法检测BBO对慢反应物质（SRS-A）生成的影响，ELISA法检测BBO对脂多糖（LPS） 诱导巨噬细胞前列腺素E₂（PGE₂）及白三烯 B₄（LTB₄）产生的影响，qRT-PCR检测BBO对LPS诱导巨噬细胞<italic>COX-2、5-LOX、FLAP</italic>和<italic>RelB</italic>表达的影响，Western blot检测BBO对NF-κB非经典通路蛋白肿瘤坏死因子受体作用因子3（TRAF3）、肿瘤坏死因子受体作用因子2（TRAF2）、NF-κB 诱导激酶（NIK）、p100和RelB浓度的影响。…”
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长白山区三条河流鱼类生物量与中华秋沙鸭数量关系 by 罗玉梅, 王卓聪, 史国强, 张国利, 姜权, 邱宝鸿, 张德文, 朴正吉, 朴龙国

“…2018—2021年，对长白山区中华秋沙鸭（<italic>Mergus</italic> <italic>squamatus</italic>）繁殖流域的富尔河、古洞河、头道白河开展鱼类资源调查，同时记录中华秋沙鸭繁殖情况，并分析鱼类生物量和中华秋沙鸭雌鸟和幼鸟数量的相关性。…”
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Ice/cold Stimulation on Post-stroke with Dysphagia: A Systematic Review by Rongqing LI, Wenying LIN, Jinxiu CHEN, Zhuangmiao LI

“…The results of meta-analyses showed that the total effective rate was not affected by the means of ice/cold stimulation and duration, the total effective rate of the intervention group was higher than that in the control group, with statistical significance (<italic>P</italic>&lt;0.05), swallowing disorder functional score [SMD=-1.91, 95%<italic>CI</italic> (-2.48, -1.34), <italic>P</italic>&lt;0.000 01], the prevalence rates of aspiration pneumonia [<italic>RR</italic>=0.30, 95%<italic>CI</italic> (0.18, 0.48), <italic>P</italic>&lt;0.000 01] and malnutrition [<italic>RR</italic>=0.27, 95%<italic>CI</italic> (0.09, 0.77), <italic>P</italic>=0.01] in the intervention group was lower than that in the control group, and the difference was statistically significant (<italic>P</italic>&lt;0.05).Conclusion:Ice/cold stimulation on post-stroke with dysphagia can improve the swallowing function, and can reduce the prevalence rates of aspiration pneumonia and malnutrition. …”
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