Entre gouvernance locale et institutionnalisation des territoires by Vincent Andreu-Boussut, Claire Choblet

“…For less than a decade, the European Commission has been working towards the promotion of the concept of Integrated Coastal Zone Management (ICZM), which aims at identifying coherent coastal territories where all the various stakes and stakeholders could be taken into account. …”
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Effect of Transcranial Direct Current Stimulation in the Treatment of Aphasia after Stroke：A Meta-Analysis by CUI Ying, LI Bo, TIAN Guang

“…The results of meta-analysis showed that, (1) Clinical efficacy: compared with the control group, the clinical effect of the experimental group was higher [<italic>OR</italic>=3.46, 95% <italic>CI</italic> (2.30, 5.21), <italic>P</italic>&lt;0.001]. (2) WAB score: compared with the control group, the WAB- aphasia quotient (WAB-AQ) score of the experimental group was significantly higher [<italic>MD</italic>=14.06, 95% <italic>CI</italic> (11.82, 16.29), <italic>Z</italic>=12.32, <italic>P</italic>&lt;0.000 01]，WAB-spontaneous language score was significantly higher [<italic>MD</italic>=2.13, 95% <italic>CI</italic> (1.32, 2.94), <italic>Z</italic>=5.17, <italic>P</italic>&lt;0.000 01], WAB-listening comprehension score was significantly higher [<italic>MD</italic>=0.50, 95% <italic>CI</italic> (0.05,0.95)], <italic>Z</italic>=2.20, <italic>P</italic>=0.03], WAB-retelling score was significantly higher [<italic>MD</italic>=2.58,95% <italic>CI</italic> (2.18,2.98), <italic>Z</italic>=12.54, <italic>P</italic>&lt;0.000 01] and WAB-naming score was significantly higher [<italic>MD</italic>=2.07, 95% <italic>CI</italic> (1.63, 2.50), <italic>Z</italic>=9.28, <italic>P</italic>&lt;0.000 01]. (3) Picture naming test: compared with the control group, the score of picture naming test in the experimental group was higher [<italic>MD</italic>=23.17, 95% <italic>CI</italic> (10.11, 36.23), <italic>Z</italic>=3.48, <italic>P</italic>=0.000 5]. (4) CADL score: compared with the control group, the CADL score of the experimental group was higher [<italic>MD</italic>=15.08, 95% <italic>CI</italic> (10.88, 19.27), <italic>Z</italic>=7.05, <italic>P</italic>&lt;0.000 01].ConclusiontDCS can effectively improve the communication ability of daily life, picture naming ability and language abilities of spontaneous language, listening comprehension, retelling and naming in patients with aphasia after stroke, with clinical efficacy and good safety. …”
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组蛋白H3的22个赖氨酸去甲基化酶对胎鼠棕色脂肪细胞分化的调控作用 by 武晓慧, 徐玉乔, 张丰, 郜松, 魏佳昶, 许久航, 李青, 苏兴利

“…Realtime RT-qPCR法检测随着小鼠胚胎的发育成熟，棕色脂肪标志基因<italic>Ucp1</italic>、<italic>Cidea</italic>、<italic>Prdml6</italic>及脂肪细胞分化基因<italic>Pparγ</italic>的表达情况和棕色脂肪中组蛋白H3的22种赖氨酸去甲基化酶的基因表达情况。…”
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Meta-Analysis of Daoyin Therapy on Therapeutic Effect and Quality of Life in Patients with Stable Angina Pectoris by QIAO Meng, WANG Zhifei, TAN Chaoren, DAI Jingang

“…Meta-analysis showed that compared with the control group, Daoyin therapy can significantly reduce the number of angina pectoris attacks [<italic>MD</italic>=-1.70, 95%<italic>CI </italic>(-2.07, -1.34), <italic>P</italic>&lt;0.000 01], shorten the duration of angina pectoris [<italic>MD</italic>=-1.17, 95%<italic>CI </italic>(-1.38, -0.96), <italic>P</italic>&lt;0.000 01], reduce SAS scores [<italic>MD</italic>=-4.71, 95%<italic>CI </italic>(-7.12, -2.31), <italic>P</italic>=0.000 1] and SDS scores [<italic>MD</italic>=-3.91, 95%<italic>CI </italic>(-5.75, -2.07), <italic>P</italic>&lt;0.000 1], and improve METs [<italic>MD</italic>=1.20, 95%<italic>CI </italic>(0.39, 2.01), <italic>P</italic>=0.004] and SAQ scores [<italic>MD</italic>=7.62, 95%<italic>CI </italic>(5.97, 9.27), <italic>P</italic>&lt;0.000 01]; Taijiquan [<italic>MD</italic>=39.52, 95%<italic>CI</italic> (19.30, 59.74), <italic>P</italic>=0.000 1] and Shaolin Neigong (<italic>P</italic>&lt;0.000 1) can improve 6MWT, while Baduanjin [<italic>MD</italic>=1.39, 95%<italic>CI </italic>(-9.13, 11.92), <italic>P</italic>=0.80] and Yixincao (<italic>P</italic>=0.30) have no statistical difference in improving 6MWT.ConclusionDaoyin therapy is effective to treat patients with stable angina pectoris of coronary heart disease by improving clinical efficacy, alleviating depression and anxiety symptoms and improving quality of life when applied alone or as an add-on measure to the conventional therapy/exercise.…”
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Systematic Evaluation of Clinical Efficacy of Shiyiwei Shenqi (Ginseng and Astraglus, Eleven Ingredients) Preparation in Adjuvant Chemotherapy for Malignant Tumor by Bowei HUANG, Yuhui ZENG, Lisha LU, Huijuan GAN

“…According to the systematic evaluation manual provided by Cochrane Collaboration, the continuity variables used mean difference (<italic>MD</italic>) and 95%confidence interval (<italic>CI</italic>) as effect indexes, the dichotomous used odds ratio (<italic>OR</italic>) and 95%<italic>CI</italic> as effect indexes. …”
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儿童全身¹⁸F-FDG PET/CT有效剂量的临床研究 by 庞春兰, 关邵翔, 杨小春, 肖子正, 林晓平

“…方法2019年7月至2020年4月在中山大学肿瘤防治中心核医学科行¹⁸F-FDG PET/CT检查的50例儿童患者，在自动曝光条件下根据ICRP102用剂量长度乘积（<italic>DLP</italic>）值估算全身CT扫描所致辐射的有效剂量（ED）及根据ICRP128推荐的方法计算¹⁸F-FDG所致辐射的有效剂量，两剂量相加得到¹⁸F-FDG PET/CT受检儿童所受辐射的总有效剂量（<italic>ED_TOTAL</italic>）。…”
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Influencing Factors of Pressure Ulcer in Critically Ill Patients by Li WANG, Qianting CAI, Ping CHEN

“…Univariate <italic>logistic</italic> regression showed that higher age (<italic>OR</italic>=1.055,95%<italic>CI</italic>: 1.015-1.097), urinary incontinence (<italic>OR</italic>=4.500,95%<italic>CI</italic>: 1.094-18.503), higher fall score (<italic>OR</italic>=3.201,95%<italic>CI</italic>: 1.769-5.792) were risk factors, while higher education level (<italic>OR</italic>=0.318,95%<italic>CI</italic>: 0.108-0.938), higher Braden score (<italic>OR</italic>=0.396,95%<italic>CI</italic>: 0.233-0.675), Q2H turning over (<italic>OR</italic>=0.222,95%<italic>CI</italic>: 0.054-0.914) and more caregivers (<italic>OR</italic>=0.058,95%<italic>CI</italic>: 0.008-0.424) were the protective factors for pressure ulcer. …”
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Effect of Robot-Assisted Gait Training on Lower Limb Motor Function of Children with Cerebral Palsy： A Meta-Analysis by JIANG Xiaoyu, BI Hongyan, SUN Wenyu, LIU Huifen, SU Hang, JIANG Jiahui

“…If <italic>P</italic>≥0.1 and <italic>I</italic>²≤50%, a fixed effects model would be used. …”
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Clinical Efficacy of Repetitive Transcranial Magnetic Stimulation Combined with Cognitive Training on Patients with Post Stroke Cognitive Impairment： A Meta-Analysis by LIU Changxing, GUO Xinyi, CHANG Xiang

“…The heterogeneity was determined according to the <italic>P</italic> value and <italic>I</italic>² value. …”
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Meta Analysis of Efficacy and Safety of Moxibustion on Neurogenic Bladder after Spinal Cord Injury by Xueqi HAN, Huirong HUANG, Zhongbiao XIU, Jingling WU, Qinyu LIU, Shaofang MIAO, Xiaona YAN

“…According to the systematic review manual provided by the Cochrane Collaboration Network, continuous variables use mean difference (<italic>MD</italic>) and 95%confidence interval (<italic>CI</italic>) as indicators, and binary variables use risk ratio (<italic>RR</italic>) and 95%<italic>CI</italic> as indicators. …”
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Meta Analysis of the Randomized Controlled Trial of Acupuncture for Ankylosing Spondylitis by Ping LI, Yinjie WANG, Jigang TIAN

“…Bi-categorized variables were represented by risk rate(<italic>RR</italic>)or odds ratio(<italic>OR</italic>)and its 95%confidence interval(<italic>CI</italic>)and continuous variables were represented by weighted mean difference(<italic>MD</italic>)and its 95%<italic>CI</italic>.Results:Finally, 11 clinical randomized controlled trials were included. …”
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Topological Analysis of Brain Glucose Metabolic Connectivity Networks of Patients with Type 2 Diabetes Mellitus Combined with Mild Cognitive Impairment by LIANG Shengxiang, YANG Junchao, ZHANG Yusi, YIN Xiaolong, HUANG Li, LI Zuanfang

“…Compared with the control group, the degree centralities of the left parahippocampal gyrus (<italic>P</italic>=0.005), left hippocampus (<italic>P</italic>=0.013), left subparietal marginal angular gyrus (<italic>P</italic>=0.031), left angular gyrus (<italic>P</italic>=0.034), right angular gyrus (<italic>P</italic>=0.013), right subparietal marginal angular gyrus (<italic>P</italic>=0.044), and right parahippocampal gyrus (<italic>P</italic>=0.024) of the observation group were significantly lower. …”
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紫云英苷抑制APP/PS1小鼠大脑皮质神经元凋亡 by 王姝涵, 杨翠珠, 张润恒, 林佳泓, 杨雅琪, 刘靖, 李国营, 马宇昕

“…腹腔注射给药AST，每日一次，连续给药一个月后，Tunel染色法检测APP/PS1小鼠大脑皮质内神经元凋亡情况；免疫荧光染色法检测APP/PS1小鼠大脑皮质内神经元凋亡相关蛋白<italic>Bax</italic>、<italic>Bcl-2</italic>、<italic>Caspase9</italic>、<italic>Cleaved-Caspase3</italic>表达情况；Western blot法检测APP/PS1小鼠大脑皮质内<italic>Bax</italic>、<italic>Bcl-2</italic>、<italic>Caspase9</italic>及<italic>Caspase3</italic>表达水平的变化。…”
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家庭亲密度和适应性与学龄前儿童饮食行为的关联 by 黄诗雅, 周海山, 张超宇, 牟劲松, 梁鸿迪, 张彩霞

“…结果家庭亲密度类型和适应性类型与饮食行为的七个维度：挑食（<italic>R²</italic>=0.252， <italic>F</italic>=114.457，<italic> P</italic>&lt;0.001）、食物响应（<italic>R²</italic> = 0.111， <italic>F</italic>=24.973， <italic>P</italic>&lt;0.001）、不良进食习惯（<italic>R²</italic>= 0.304， <italic>F</italic>=139.658， <italic>P</italic>&lt;0.001）、过饱响应（<italic>R² </italic>= 0.259， <italic>F</italic>=105.332， <italic>P</italic>&lt;0.001）、外因性进食（<italic>R²</italic> = 0.182， <italic>F</italic>=50.150， <italic>P</italic>&lt;0.001）、情绪性进食（<italic>R²</italic> = 0.234， <italic>F</italic>=91.084， <italic>P</italic>&lt;0.001）、主动进食能力（<italic>R² </italic>= 0.349， <italic>F</italic>=168.608， <italic>P</italic>&lt;0.001）均显著相关。…”
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台状蚀坑阶梯形貌对锈蚀结构钢应力集中效应的影响 by 古松, 曾生辉, 任松波, 顾颖, 孔超

“…采用数值分析方法，建立了台状蚀坑损伤三维有限元模型，分别讨论了台状蚀坑体态倾角<italic>θ</italic>、台阶宽度比<italic>R</italic>以及台阶宽高比<italic>S</italic>等对应力集中系数<italic>K</italic>_t的影响规律。…”
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Ziwuliuzhu Acupuncture on Primary Insomnia Therapy: A Meta-Analysis by Dunbing HUANG, Shinong GU, Fanping ZHOU, Sai'e HUANG

“…The results of Meta-analysis indicated that to improve the effective rate, Ziwuliuzhu acupuncture was better than non-Ziwuliuzhu acupuncture [<italic>RR</italic>=1.20; 95%<italic>CI</italic>(1.13, 1.27); <italic>Z</italic>=6.23, <italic>P</italic>&lt;0.000 01]; to improving the effective cure rate, Ziwuliuzhu acupuncture was better than non-Ziwuliuzhu acupuncture [<italic>RR</italic>=1.71; 95%<italic>CI</italic>(1.33, 2.19); <italic>Z</italic>=4.18, <italic>P</italic>&lt;0.000 1]; to improving the PSQI score, Ziwuliuzhu acupuncture was better than non-Ziwuliuzhu acupuncture [<italic>MD</italic>=-2.05; 95%<italic>CI</italic>(-2.43, -1.66); <italic>Z</italic>=10.31, <italic>P</italic>&lt;0.000 01]; to improving the sleep rate, Ziwuliuzhu acupuncture was better than non-Ziwuliuzhu acupuncture [<italic>MD</italic>=6.09; 95%<italic>CI</italic>(2.32, 9.85); <italic>Z</italic>=3.17, <italic>P</italic>=0.002].Conclusion:Ziwuliuzhu acupuncture has a great advantage compare ith non-Ziwuliuzhu acupuncture in the treatment of primary insomnia, but larger scale and high quality RCTs are needed to verify the aforementioned conclusion.…”
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基于CUMS模型探究抑郁症对细菌感染的影响及作用 by 徐磊, 赵润平, 陈洁云, 杨艳鲜, 郭锡龙, 代敏, 田国宝, 秦丽娜

“…此外，对感染前收集的小鼠粪便样本进行肠道菌群16S rDNA基因测序分析，并检测未感染小鼠结肠组织中<italic>NF-κB</italic>/<italic>NLRP3</italic>信号通路的表达水平。…”
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阿魏酸通过胰岛素/IGF信号通路和DAF-16促进秀丽隐杆线虫寿命和应激抵抗力 by 况琪斐, 陈巧超, 张玲, 何文, 裴中

“…方法使用秀丽隐杆线虫作为抗衰老模型，给予不同浓度的阿魏酸（0、1、10、50 mmol/L），探究其对线虫寿命、抗应激能力、脂褐素水平的调控作用；使用qPCR筛选衰老相关基因，采用<italic>daf-2</italic>（<italic>DR1572</italic>）、<italic>daf-16</italic>（<italic>CF1038</italic>）突变体线虫，对阿魏酸的潜在作用机理进行初步探讨。…”
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Effect of Task Oriented Training on Gross Motor Dysfunction for Children with Cerebral Palsy： A Meta-Analysis by LI Yang, CHEN Ying, ZHU Xiangyu, SHI Jiehong, FENG Yuan, WU Wenlei, FU Ruochen

“…Meta-analysis results showed that, compared with the control group, the GMFM scale standing score in the experimental group was higher [<italic>SMD</italic>=0.78, 95% <italic>CI</italic> (0.59, 0.98), <italic>P</italic>&lt;0.000 01], walking, running and jumping scores was higher [<italic>SMD</italic>=4.05, 95% <italic>CI</italic> (2.06, 6.05), <italic>P</italic>&lt;0.000 01], GMFM scale overall score was higher [<italic>SMD</italic>=10.23, 95% <italic>CI</italic> (7.00, 13.46), <italic>P</italic>&lt;0.000 01], PEDI score was higher [<italic>SMD</italic>=6.87, 95% <italic>CI</italic> (4.19, 9.54), <italic>P</italic>&lt;0.000 01], TUG test time was shorter [<italic>SMD</italic>=-3.17, 95% <italic>CI</italic> (-4.84, -1.49), <italic>P</italic>=0.000 2], and BBS score was higher [<italic>SMD</italic>=5.26, 95% <italic>CI</italic> (4.05, 6.46), <italic>P</italic>&lt;0.000 01].ConclusionTask oriented training can effectively improve the gross motor function (such as walking, running, jumping, etc.) of children with cerebral palsy, shorten the TUG test time, and improve their balance function and activities of daily living.…”
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狼疮肾炎DN2细胞的CRAC和病情活动相关性分析 by 李雪, 曾琴, 王双, 叶宝奎, 杨念生

“…目的探讨狼疮肾炎（LN）患者外周血双阴性B细胞2（DN2）细胞的比例，以及DN2细胞钙离子释放激活的钙离子通道（CRAC）蛋白表达情况及其与临床相关性。方法流式细胞学检测健康对照者（HC， <italic>n</italic>=15）、狼疮肾炎（LN， <italic>n</italic>=30）、类风湿关节炎（RA， <italic>n</italic>=15）和原发性干燥综合征（pSS， <italic>n</italic>=15）患者外周血DN2细胞的比例以及DN2细胞CRAC蛋白Orai1表达情况；用单因素方差分析四组间差异，用Pearson相关性分析探讨Orai1表达与LN疾病活动指标的相关性。…”
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